Does erythropoietin regulate TRPC channels in red blood cells?

Autores
Danielczok, Jens; Hertz, Laura; Ruppenthal, Sandra; Kaiser, Elisabeth; Petkova-Kirova, Polina; Bogdanova, Anna; Krause, Elmar; Lipp, Peter; Freichel, Marc; Kaestner, Lars; Birnbaumer, Lutz
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Fil: Danielczok, Jens. Saarland University. Research Centre for Molecular Imaging and Screening; Alemania
Fil: Hertz, Laura. Saarland University. Research Centre for Molecular Imaging and Screening; Alemania
Fil: Ruppenthal, Sandra. Saarland University. Research Centre for Molecular Imaging and Screening; Alemania
Fil: Kaiser, Elisabeth. Saarland University. Research Centre for Molecular Imaging and Screening; Alemania
Fil: Petkova-Kirova, Polina. Saarland University. Research Centre for Molecular Imaging and Screening; Alemania
Fil: Bogdanova, Anna. University of Zuerich. Vetsuisse Faculty; Suiza
Fil: Krause, Elmar. Saarland University. Physiology; Alemania
Fil: Lipp, Peter. Jens. Saarland University. Research Centre for Molecular Imaging and Screening; Alemania
Fil: Freichel, Marc. University Heidelberg. Institute for Pharmacology; Alemania
Fil: Kaestner, Lars. Saarland University. Experimental Physics; Alemania
Fil: Kaestner, Lars. Saarland University Theoretical Medicine and Biosciences; Alemania
Fil: Birnbaumer, Lutz. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina
Fil: Birnbaumer, Lutz. National Institute of Environmental Health Sciences. Neurobiology Laboratory; Estados Unidos
Abstract: Cation channels play an essential role in red blood cells (RBCs) ion homeostasis. One set of ion channels are the transient receptor potential channels of canonical type (TRPC channels). The abundance of these channels in primary erythroblasts, erythroid cell lines and RBCs was associated with an increase in intracellular Ca2+ upon stimulation with Erythropoietin (Epo). In contrast two independent studies on Epo-treated patients revealed diminished basal Ca2+ concentration or reduced phosphatidylserine exposure to the outer membrane leaflet.
Fuente
Cellular Physiology and Biochemistry. 2017;41(3):1219-1228
Materia
GLOBULOS ROJOS
METABOLISMO
CALCIO
CELULAS
SANGRE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
Repositorio Institucional (UCA)
Institución
Pontificia Universidad Católica Argentina
OAI Identificador
oai:ucacris:123456789/8729
Acceder
id RIUCA_5cd2b92e0a39c653a55a2e2237c6a963
oai_identifier_str oai:ucacris:123456789/8729
network_acronym_str RIUCA
repository_id_str 2585
network_name_str Repositorio Institucional (UCA)
spelling Does erythropoietin regulate TRPC channels in red blood cells?Danielczok, JensHertz, LauraRuppenthal, SandraKaiser, ElisabethPetkova-Kirova, PolinaBogdanova, AnnaKrause, ElmarLipp, PeterFreichel, MarcKaestner, LarsBirnbaumer, LutzGLOBULOS ROJOSMETABOLISMOCALCIOCELULASSANGREFil: Danielczok, Jens. Saarland University. Research Centre for Molecular Imaging and Screening; AlemaniaFil: Hertz, Laura. Saarland University. Research Centre for Molecular Imaging and Screening; AlemaniaFil: Ruppenthal, Sandra. Saarland University. Research Centre for Molecular Imaging and Screening; AlemaniaFil: Kaiser, Elisabeth. Saarland University. Research Centre for Molecular Imaging and Screening; AlemaniaFil: Petkova-Kirova, Polina. Saarland University. Research Centre for Molecular Imaging and Screening; AlemaniaFil: Bogdanova, Anna. University of Zuerich. Vetsuisse Faculty; SuizaFil: Krause, Elmar. Saarland University. Physiology; AlemaniaFil: Lipp, Peter. Jens. Saarland University. Research Centre for Molecular Imaging and Screening; AlemaniaFil: Freichel, Marc. University Heidelberg. Institute for Pharmacology; AlemaniaFil: Kaestner, Lars. Saarland University. Experimental Physics; AlemaniaFil: Kaestner, Lars. Saarland University Theoretical Medicine and Biosciences; AlemaniaFil: Birnbaumer, Lutz. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; ArgentinaFil: Birnbaumer, Lutz. National Institute of Environmental Health Sciences. Neurobiology Laboratory; Estados UnidosAbstract: Cation channels play an essential role in red blood cells (RBCs) ion homeostasis. One set of ion channels are the transient receptor potential channels of canonical type (TRPC channels). The abundance of these channels in primary erythroblasts, erythroid cell lines and RBCs was associated with an increase in intracellular Ca2+ upon stimulation with Erythropoietin (Epo). In contrast two independent studies on Epo-treated patients revealed diminished basal Ca2+ concentration or reduced phosphatidylserine exposure to the outer membrane leaflet.Karger Publishers2017info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://repositorio.uca.edu.ar/handle/123456789/87291015-89871421-977810.1159/00046438428268218Danielczok J, Hertz L, Ruppenthal S, et al. Does Erythropoietin Regulate TRPC Channels in Red Blood Cells? [en línea] Cellular Physiology and Biochemistry. 2017;41(3):1219-1228. doi:10.1159/000464384 Disponible en: https://repositorio.uca.edu.ar/handle/123456789/8729Cellular Physiology and Biochemistry. 2017;41(3):1219-1228reponame:Repositorio Institucional (UCA)instname:Pontificia Universidad Católica Argentinaenginfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/4.0/2025-07-03T10:56:54Zoai:ucacris:123456789/8729instacron:UCAInstitucionalhttps://repositorio.uca.edu.ar/Universidad privadaNo correspondehttps://repositorio.uca.edu.ar/oaiclaudia_fernandez@uca.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:25852025-07-03 10:56:55.131Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentinafalse
dc.title.none.fl_str_mv Does erythropoietin regulate TRPC channels in red blood cells?
title Does erythropoietin regulate TRPC channels in red blood cells?
spellingShingle Does erythropoietin regulate TRPC channels in red blood cells?
Danielczok, Jens
GLOBULOS ROJOS
METABOLISMO
CALCIO
CELULAS
SANGRE
title_short Does erythropoietin regulate TRPC channels in red blood cells?
title_full Does erythropoietin regulate TRPC channels in red blood cells?
title_fullStr Does erythropoietin regulate TRPC channels in red blood cells?
title_full_unstemmed Does erythropoietin regulate TRPC channels in red blood cells?
title_sort Does erythropoietin regulate TRPC channels in red blood cells?
dc.creator.none.fl_str_mv Danielczok, Jens
Hertz, Laura
Ruppenthal, Sandra
Kaiser, Elisabeth
Petkova-Kirova, Polina
Bogdanova, Anna
Krause, Elmar
Lipp, Peter
Freichel, Marc
Kaestner, Lars
Birnbaumer, Lutz
author Danielczok, Jens
author_facet Danielczok, Jens
Hertz, Laura
Ruppenthal, Sandra
Kaiser, Elisabeth
Petkova-Kirova, Polina
Bogdanova, Anna
Krause, Elmar
Lipp, Peter
Freichel, Marc
Kaestner, Lars
Birnbaumer, Lutz
author_role author
author2 Hertz, Laura
Ruppenthal, Sandra
Kaiser, Elisabeth
Petkova-Kirova, Polina
Bogdanova, Anna
Krause, Elmar
Lipp, Peter
Freichel, Marc
Kaestner, Lars
Birnbaumer, Lutz
author2_role author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv GLOBULOS ROJOS
METABOLISMO
CALCIO
CELULAS
SANGRE
topic GLOBULOS ROJOS
METABOLISMO
CALCIO
CELULAS
SANGRE
dc.description.none.fl_txt_mv Fil: Danielczok, Jens. Saarland University. Research Centre for Molecular Imaging and Screening; Alemania
Fil: Hertz, Laura. Saarland University. Research Centre for Molecular Imaging and Screening; Alemania
Fil: Ruppenthal, Sandra. Saarland University. Research Centre for Molecular Imaging and Screening; Alemania
Fil: Kaiser, Elisabeth. Saarland University. Research Centre for Molecular Imaging and Screening; Alemania
Fil: Petkova-Kirova, Polina. Saarland University. Research Centre for Molecular Imaging and Screening; Alemania
Fil: Bogdanova, Anna. University of Zuerich. Vetsuisse Faculty; Suiza
Fil: Krause, Elmar. Saarland University. Physiology; Alemania
Fil: Lipp, Peter. Jens. Saarland University. Research Centre for Molecular Imaging and Screening; Alemania
Fil: Freichel, Marc. University Heidelberg. Institute for Pharmacology; Alemania
Fil: Kaestner, Lars. Saarland University. Experimental Physics; Alemania
Fil: Kaestner, Lars. Saarland University Theoretical Medicine and Biosciences; Alemania
Fil: Birnbaumer, Lutz. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina
Fil: Birnbaumer, Lutz. National Institute of Environmental Health Sciences. Neurobiology Laboratory; Estados Unidos
Abstract: Cation channels play an essential role in red blood cells (RBCs) ion homeostasis. One set of ion channels are the transient receptor potential channels of canonical type (TRPC channels). The abundance of these channels in primary erythroblasts, erythroid cell lines and RBCs was associated with an increase in intracellular Ca2+ upon stimulation with Erythropoietin (Epo). In contrast two independent studies on Epo-treated patients revealed diminished basal Ca2+ concentration or reduced phosphatidylserine exposure to the outer membrane leaflet.
description Fil: Danielczok, Jens. Saarland University. Research Centre for Molecular Imaging and Screening; Alemania
publishDate 2017
dc.date.none.fl_str_mv 2017
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://repositorio.uca.edu.ar/handle/123456789/8729
1015-8987
1421-9778
10.1159/000464384
28268218
Danielczok J, Hertz L, Ruppenthal S, et al. Does Erythropoietin Regulate TRPC Channels in Red Blood Cells? [en línea] Cellular Physiology and Biochemistry. 2017;41(3):1219-1228. doi:10.1159/000464384 Disponible en: https://repositorio.uca.edu.ar/handle/123456789/8729
url https://repositorio.uca.edu.ar/handle/123456789/8729
identifier_str_mv 1015-8987
1421-9778
10.1159/000464384
28268218
Danielczok J, Hertz L, Ruppenthal S, et al. Does Erythropoietin Regulate TRPC Channels in Red Blood Cells? [en línea] Cellular Physiology and Biochemistry. 2017;41(3):1219-1228. doi:10.1159/000464384 Disponible en: https://repositorio.uca.edu.ar/handle/123456789/8729
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/4.0/
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Karger Publishers
publisher.none.fl_str_mv Karger Publishers
dc.source.none.fl_str_mv Cellular Physiology and Biochemistry. 2017;41(3):1219-1228
reponame:Repositorio Institucional (UCA)
instname:Pontificia Universidad Católica Argentina
reponame_str Repositorio Institucional (UCA)
collection Repositorio Institucional (UCA)
instname_str Pontificia Universidad Católica Argentina
repository.name.fl_str_mv Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentina
repository.mail.fl_str_mv claudia_fernandez@uca.edu.ar
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score 12.993085

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