Assessment of ataxia rating scales and cerebellar functional tests : critique and recommendations

• Autores: Pérez Lloret, Santiago; Warrenburg, Bart van de; Rossi, Malco Damián; Rodríguez-Blázquez, Carmen; Zesiewicz, Theresa; Saute, Jonas A. M.; Durr, Alexandra; Nishizawa, Masatoyo; Martinez-Martin, Pablo; Stebbins, Glenn T.; Schrag, Anette; Skorvanek, Matej
• Año de publicación: 2020
• Idioma: inglés
• Tipo de recurso: artículo
• Fuente: Movement Disorders 2020
• Materia: ATAXIA; DESORDENES CEREBRALES; ENSAYO CLINICO; ESCALA DE CLASIFICACION; NEUROLOGIA
• Institución: Pontificia Universidad Católica Argentina

Fil: Pérez Lloret, Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Pérez Lloret, Santiago. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas; Argentina
Fil: Pérez Lloret. Universidad de Buenos Aires. Facultad de Medicina; Argentina
Fil: Warrenburg, Bart van de. Radboud University Medical Center. Center of Expertise for Parkinson and Movement Disorders. Department of Neurology. 4Donders Institute for Brain, Cognition and Behavior; Países Bajos
Fil: Rossi, Malco. Raul Carrea Institute for Neurological Research. Movement Disorders Section; Argentina
Fil: Rodríguez-Blázquez, Carmen. Institute of Health Carlos III and CIBERNED. National Centre of Epidemiology; España
Fil: Zesiewicz, Theresa. University of South Florida. Department of Neurology; Estados Unidos
Fil: Saute, Jonas A. M. Hospital de Clínicas de Porto Alegre; Brasil
Fil: Saute, Jonas A. M. Universidade Federal do Rio Grande do Sul; Brasil
Fil: Durr, Alexandra. 12Sorbonne Université. Institut du Cerveau-Paris Brain Institute; Francia
Fil: Durr, Alexandra. University Hospital Pitié-Salpêtrière; Francia
Fil: Nishizawa, Masatoyo. Niigata University. Brain Research Institute; Japón
Fil: Martinez-Martin, Pablo. Carlos III Institute of Health. Center for Networked Biomedical Research in Neurodegenerative Diseases; España
Fil: Stebbins, Glenn T. Rush University Medical Center. Department of Neurological Sciences; Estados Unidos
Fil: Schrag, Anette. Royal Free Campus. UCL Institute of Neurology. Department of Clinical Neurosciences; Reino Unido
Fil: Skorvanek, Matej. P. J. Safarik University. Department of Neurology, Faculty of Medicine; Eslovaquia
Fil: Skorvanek, Matej. University Hospital L. Pasteur. Department of Neurology; Eslovaquia
Background: We assessed the clinimetric properties of ataxia rating scales and functional tests, and made recommendations regarding their use. Methods: A systematic literature search was conducted to identify the instruments used to rate ataxia symptoms. The identified rating scales and functional ability tests were reviewed and ranked by the panel as “recommended,” “suggested,” or “listed” for the assessment of patients with discrete cerebellar disorders, using previously established criteria. Results: We reviewed 14 instruments (9 rating scales and 5 functional tests). “Recommended” rating scales for the assessment of symptoms severity were: for Friedreich’s ataxia, the Friedreich’s Ataxia Rating Scale, the International Cooperative Ataxia Rating Scale (ICARS), and the Scale for the Assessment and Rating of Ataxia (SARA); for spinocerebellar ataxias, ICARS and SARA; for ataxia telangiectasia: ICARS and SARA; for brain tumors, SARA; for congenital disorder of glycosylation-phosphomannomutase-2 deficiency, ICARS; for cerebellar symptoms in multiple sclerosis, ICARS; for cerebellar symptoms in multiple system atrophy: Unified Multiple System Atrophy Rating Scale and ICARS; and for fragile X–associated tremor ataxia syndrome, ICARS. “Recommended” functional tests were: for Friedreich’s ataxia, Ataxia Functional Composite Score and Composite Cerebellar Functional Severity Score; and for spinocerebellar ataxias, Ataxia Functional Composite Score, Composite Cerebellar Functional Severity Score, and SCA Functional Index.