Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)

Autores: Förster, Daniel W.; Jones, Eleanor P.; Jóhannesdóttir, Fríða; Gabriel, Sofia I.; Giménez, Mabel Dionisia; Panithanarak, Thadsin; Hauffe, Heidi Christine; Searle, Jeremy B.
Año de publicación: 2016
Idioma: inglés
Tipo de recurso: artículo
Estado: versión publicada
Descripción: Fil: Förster, Daniel W. Universidad de York. Departamento de Biología; Reino Unido.
Fil: Förster, Daniel W. Leibniz-Institute for Zoo and Wildlife Research. Department of Evolutionary Genetics; Alemania.
Fil: Jones, Eleanor P. Universidad de York. Departamento de Biología; Reino Unido.
Fil: Jones, Eleanor P. Fera Science; Reino Unido.
Fil: Jóhannesdóttir, Fríða. Universidad de York. Departamento de Biología; Reino Unido.
Fil: Jóhannesdóttir, Fríða. Universidad de Uppsala. Departamento de Ecología y Genética; Suecia.
Fil: Jóhannesdóttir, Fríða. Universidad de Cornell. Departamento de Ecología y Evolución; Estados Unidos.
Fil: Gabriel, Sofia I. Universidad de Aveiro. Centro de Estudio del Ambiente y del Mar; Portugal.
Fil: Gabriel, Sofia I. Universidad de Lisboa. Facultad de Ciencias. Departamento de Biología Animal; Portugal.
Fil: Giménez, Mabel Dionisia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico (Nordeste). Instituto de Biología Subtropical. Instituto de Biología Subtropical Nodo Posadas; Argentina.
Fil: Giménez, Mabel Dionisia. Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales. Instituto de Biología Subtropical. Instituto de Biología Subtropical Nodo Posadas; Argentina.
Fil: Giménez, Mabel Dionisia. Universidad de York. Departamento de Biología; Reino Unido.
Fil: Panithanarak, Thadsin. Universidad de Burapha. Instituto de Ciencias Marinas; Tailandia.
Fil: Hauffe, Heidi Christine. Universidad de York. Departamento de Biología; Reino Unido.
Fil: Hauffe, Heidi Christine. Instituto Agrario San Michele All'adige. Fondazione Edmund Mach. Centro Ricerca e Innovazione. Departamento de Biodiversidad y Ecología Molecular; Italia.
Fil: Searle, Jeremy B. Universidad de York. Departamento de Biología; Reino Unido.
Fil: Searle, Jeremy B. Universidad de Cornell. Departamento de Ecología y Evolución; Estados Unidos.
The importance of chromosomal rearrangements for speciation can be inferred from studies of genetic exchange between hybridising chromosomal races within species. Reduced fertility or recombination suppression in karyotypic hybrids has the potential to maintain or promote genetic differentiation in genomic regions near rearrangement breakpoints. We studied genetic exchange between two hybridising groups of chromosomal races of house mouse in Upper Valtellina (Lombardy, Italy), using microsatellites. These groups differ by Robertsonian fusions and/or whole-arm reciprocal translocations such that F1 hybrids have a chain-of-five meiotic configuration. Previous studies showed genetic differentiation in two chromosomes in the chain-of-five (10 and 12) close to their centromeres (i.e. the rearrangement breakpoints); we have shown here that the centromeric regions of the other two chromosomes in the chain (2 and 8) are similarly differentiated. The internal chromosomes of the chain (8 and 12) show the greatest differentiation, which may reflect pairing and recombination properties of internal and external elements in a meiotic chain. Importantly, we found that centromeric regions of some non-rearranged chromosomes also showed genetic differentiation between the hybridising groups, indicating a complex interplay between chromosomal rearrangements and other parts of the genome in maintaining or promoting differentiation and potentially driving speciation between chromosomal races.
Materia: Chromosomal hybrid zone
Introgression
Microsatellites
Robertsonian fusión
Speciation
Nivel de accesibilidad: acceso abierto
Condiciones de uso: Atribución-NoComercial-CompartirIgual 4.0 Internacional
Repositorio
Institución: Universidad Nacional de Misiones
OAI Identificador: oai:rid.unam.edu.ar:20.500.12219/4477

Acceder

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repository_id_str
network_name_str	Repositorio Institucional Digital de la Universidad Nacional de Misiones (UNaM)
spelling	Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)Förster, Daniel W.Jones, Eleanor P.Jóhannesdóttir, FríðaGabriel, Sofia I.Giménez, Mabel DionisiaPanithanarak, ThadsinHauffe, Heidi ChristineSearle, Jeremy B.Chromosomal hybrid zoneIntrogressionMicrosatellitesRobertsonian fusiónSpeciationFil: Förster, Daniel W. Universidad de York. Departamento de Biología; Reino Unido.Fil: Förster, Daniel W. Leibniz-Institute for Zoo and Wildlife Research. Department of Evolutionary Genetics; Alemania.Fil: Jones, Eleanor P. Universidad de York. Departamento de Biología; Reino Unido.Fil: Jones, Eleanor P. Fera Science; Reino Unido.Fil: Jóhannesdóttir, Fríða. Universidad de York. Departamento de Biología; Reino Unido.Fil: Jóhannesdóttir, Fríða. Universidad de Uppsala. Departamento de Ecología y Genética; Suecia.Fil: Jóhannesdóttir, Fríða. Universidad de Cornell. Departamento de Ecología y Evolución; Estados Unidos.Fil: Gabriel, Sofia I. Universidad de Aveiro. Centro de Estudio del Ambiente y del Mar; Portugal.Fil: Gabriel, Sofia I. Universidad de Lisboa. Facultad de Ciencias. Departamento de Biología Animal; Portugal.Fil: Giménez, Mabel Dionisia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico (Nordeste). Instituto de Biología Subtropical. Instituto de Biología Subtropical Nodo Posadas; Argentina.Fil: Giménez, Mabel Dionisia. Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales. Instituto de Biología Subtropical. Instituto de Biología Subtropical Nodo Posadas; Argentina.Fil: Giménez, Mabel Dionisia. Universidad de York. Departamento de Biología; Reino Unido.Fil: Panithanarak, Thadsin. Universidad de Burapha. Instituto de Ciencias Marinas; Tailandia.Fil: Hauffe, Heidi Christine. Universidad de York. Departamento de Biología; Reino Unido.Fil: Hauffe, Heidi Christine. Instituto Agrario San Michele All'adige. Fondazione Edmund Mach. Centro Ricerca e Innovazione. Departamento de Biodiversidad y Ecología Molecular; Italia.Fil: Searle, Jeremy B. Universidad de York. Departamento de Biología; Reino Unido.Fil: Searle, Jeremy B. Universidad de Cornell. Departamento de Ecología y Evolución; Estados Unidos.The importance of chromosomal rearrangements for speciation can be inferred from studies of genetic exchange between hybridising chromosomal races within species. Reduced fertility or recombination suppression in karyotypic hybrids has the potential to maintain or promote genetic differentiation in genomic regions near rearrangement breakpoints. We studied genetic exchange between two hybridising groups of chromosomal races of house mouse in Upper Valtellina (Lombardy, Italy), using microsatellites. These groups differ by Robertsonian fusions and/or whole-arm reciprocal translocations such that F1 hybrids have a chain-of-five meiotic configuration. Previous studies showed genetic differentiation in two chromosomes in the chain-of-five (10 and 12) close to their centromeres (i.e. the rearrangement breakpoints); we have shown here that the centromeric regions of the other two chromosomes in the chain (2 and 8) are similarly differentiated. The internal chromosomes of the chain (8 and 12) show the greatest differentiation, which may reflect pairing and recombination properties of internal and external elements in a meiotic chain. Importantly, we found that centromeric regions of some non-rearranged chromosomes also showed genetic differentiation between the hybridising groups, indicating a complex interplay between chromosomal rearrangements and other parts of the genome in maintaining or promoting differentiation and potentially driving speciation between chromosomal races.Springer2016-04-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdf323.9 KBhttps://hdl.handle.net/20.500.12219/4477enginfo:eu-repo/semantics/altIdentifier/urn/https://link.springer.com/content/pdf/10.1007/s10577-016-9520-1.pdfinfo:eu-repo/semantics/openAccessAtribución-NoComercial-CompartirIgual 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-sa/4.0/reponame:Repositorio Institucional Digital de la Universidad Nacional de Misiones (UNaM)instname:Universidad Nacional de Misiones2025-09-29T15:01:51Zoai:rid.unam.edu.ar:20.500.12219/4477instacron:UNAMInstitucionalhttps://rid.unam.edu.ar/Universidad públicahttps://www.unam.edu.ar/https://rid.unam.edu.ar/oai/rsnrdArgentinaopendoar:2025-09-29 15:01:52.285Repositorio Institucional Digital de la Universidad Nacional de Misiones (UNaM) - Universidad Nacional de Misionesfalse
dc.title.none.fl_str_mv	Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)
title	Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)
spellingShingle	Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus) Förster, Daniel W. Chromosomal hybrid zone Introgression Microsatellites Robertsonian fusión Speciation
title_short	Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)
title_full	Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)
title_fullStr	Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)
title_full_unstemmed	Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)
title_sort	Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)
dc.creator.none.fl_str_mv	Förster, Daniel W. Jones, Eleanor P. Jóhannesdóttir, Fríða Gabriel, Sofia I. Giménez, Mabel Dionisia Panithanarak, Thadsin Hauffe, Heidi Christine Searle, Jeremy B.
author	Förster, Daniel W.
author_facet	Förster, Daniel W. Jones, Eleanor P. Jóhannesdóttir, Fríða Gabriel, Sofia I. Giménez, Mabel Dionisia Panithanarak, Thadsin Hauffe, Heidi Christine Searle, Jeremy B.
author_role	author
author2	Jones, Eleanor P. Jóhannesdóttir, Fríða Gabriel, Sofia I. Giménez, Mabel Dionisia Panithanarak, Thadsin Hauffe, Heidi Christine Searle, Jeremy B.
author2_role	author author author author author author author
dc.subject.none.fl_str_mv	Chromosomal hybrid zone Introgression Microsatellites Robertsonian fusión Speciation
topic	Chromosomal hybrid zone Introgression Microsatellites Robertsonian fusión Speciation
dc.description.none.fl_txt_mv	Fil: Förster, Daniel W. Universidad de York. Departamento de Biología; Reino Unido. Fil: Förster, Daniel W. Leibniz-Institute for Zoo and Wildlife Research. Department of Evolutionary Genetics; Alemania. Fil: Jones, Eleanor P. Universidad de York. Departamento de Biología; Reino Unido. Fil: Jones, Eleanor P. Fera Science; Reino Unido. Fil: Jóhannesdóttir, Fríða. Universidad de York. Departamento de Biología; Reino Unido. Fil: Jóhannesdóttir, Fríða. Universidad de Uppsala. Departamento de Ecología y Genética; Suecia. Fil: Jóhannesdóttir, Fríða. Universidad de Cornell. Departamento de Ecología y Evolución; Estados Unidos. Fil: Gabriel, Sofia I. Universidad de Aveiro. Centro de Estudio del Ambiente y del Mar; Portugal. Fil: Gabriel, Sofia I. Universidad de Lisboa. Facultad de Ciencias. Departamento de Biología Animal; Portugal. Fil: Giménez, Mabel Dionisia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico (Nordeste). Instituto de Biología Subtropical. Instituto de Biología Subtropical Nodo Posadas; Argentina. Fil: Giménez, Mabel Dionisia. Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales. Instituto de Biología Subtropical. Instituto de Biología Subtropical Nodo Posadas; Argentina. Fil: Giménez, Mabel Dionisia. Universidad de York. Departamento de Biología; Reino Unido. Fil: Panithanarak, Thadsin. Universidad de Burapha. Instituto de Ciencias Marinas; Tailandia. Fil: Hauffe, Heidi Christine. Universidad de York. Departamento de Biología; Reino Unido. Fil: Hauffe, Heidi Christine. Instituto Agrario San Michele All'adige. Fondazione Edmund Mach. Centro Ricerca e Innovazione. Departamento de Biodiversidad y Ecología Molecular; Italia. Fil: Searle, Jeremy B. Universidad de York. Departamento de Biología; Reino Unido. Fil: Searle, Jeremy B. Universidad de Cornell. Departamento de Ecología y Evolución; Estados Unidos. The importance of chromosomal rearrangements for speciation can be inferred from studies of genetic exchange between hybridising chromosomal races within species. Reduced fertility or recombination suppression in karyotypic hybrids has the potential to maintain or promote genetic differentiation in genomic regions near rearrangement breakpoints. We studied genetic exchange between two hybridising groups of chromosomal races of house mouse in Upper Valtellina (Lombardy, Italy), using microsatellites. These groups differ by Robertsonian fusions and/or whole-arm reciprocal translocations such that F1 hybrids have a chain-of-five meiotic configuration. Previous studies showed genetic differentiation in two chromosomes in the chain-of-five (10 and 12) close to their centromeres (i.e. the rearrangement breakpoints); we have shown here that the centromeric regions of the other two chromosomes in the chain (2 and 8) are similarly differentiated. The internal chromosomes of the chain (8 and 12) show the greatest differentiation, which may reflect pairing and recombination properties of internal and external elements in a meiotic chain. Importantly, we found that centromeric regions of some non-rearranged chromosomes also showed genetic differentiation between the hybridising groups, indicating a complex interplay between chromosomal rearrangements and other parts of the genome in maintaining or promoting differentiation and potentially driving speciation between chromosomal races.
description	Fil: Förster, Daniel W. Universidad de York. Departamento de Biología; Reino Unido.
publishDate	2016
dc.date.none.fl_str_mv	2016-04-05
dc.type.none.fl_str_mv	info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo
format	article
status_str	publishedVersion
dc.identifier.none.fl_str_mv	https://hdl.handle.net/20.500.12219/4477
url	https://hdl.handle.net/20.500.12219/4477
dc.language.none.fl_str_mv	eng
language	eng
dc.relation.none.fl_str_mv	info:eu-repo/semantics/altIdentifier/urn/https://link.springer.com/content/pdf/10.1007/s10577-016-9520-1.pdf
dc.rights.none.fl_str_mv	info:eu-repo/semantics/openAccess Atribución-NoComercial-CompartirIgual 4.0 Internacional http://creativecommons.org/licenses/by-nc-sa/4.0/
eu_rights_str_mv	openAccess
rights_invalid_str_mv	Atribución-NoComercial-CompartirIgual 4.0 Internacional http://creativecommons.org/licenses/by-nc-sa/4.0/
dc.format.none.fl_str_mv	application/pdf application/pdf 323.9 KB
dc.publisher.none.fl_str_mv	Springer
publisher.none.fl_str_mv	Springer
dc.source.none.fl_str_mv	reponame:Repositorio Institucional Digital de la Universidad Nacional de Misiones (UNaM) instname:Universidad Nacional de Misiones
reponame_str	Repositorio Institucional Digital de la Universidad Nacional de Misiones (UNaM)
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Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)

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