Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)

Autores
Förster, Daniel W.; Jones, Eleanor P.; Jóhannesdóttir, Fríða; Gabriel, Sofia I.; Giménez, Mabel Dionisia; Panithanarak, Thadsin; Hauffe, Heidi C.; Searle, Jeremy B.
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The importance of chromosomal rearrangements for speciation can be inferred from studies of genetic exchange between hybridising chromosomal races within species. Reduced fertility or recombination suppression in karyotypic hybrids has the potential to maintain or promote genetic differentiation in genomic regions near rearrangement breakpoints. We studied genetic exchange between two hybridising groups of chromosomal races of house mouse in Upper Valtellina (Lombardy, Italy), using microsatellites. These groups differ by Robertsonian fusions and/or whole-arm reciprocal translocations such that F1 hybrids have a chain-of-five meiotic configuration. Previous studies showed genetic differentiation in two chromosomes in the chain-of-five (10 and 12) close to their centromeres (i.e. the rearrangement breakpoints); we have shown here that the centromeric regions of the other two chromosomes in the chain (2 and 8) are similarly differentiated. The internal chromosomes of the chain (8 and 12) show the greatest differentiation, which may reflect pairing and recombination properties of internal and external elements in a meiotic chain. Importantly, we found that centromeric regions of some non-rearranged chromosomes also showed genetic differentiation between the hybridising groups, indicating a complex interplay between chromosomal rearrangements and other parts of the genome in maintaining or promoting differentiation and potentially driving speciation between chromosomal races.
Fil: Förster, Daniel W.. University of York; Reino Unido. Leibniz-Institute for Zoo and Wildlife Research; Alemania
Fil: Jones, Eleanor P.. University of York; Reino Unido. Fera Science; Reino Unido
Fil: Jóhannesdóttir, Fríða. University of York; Reino Unido. Uppsala University; Suecia. Cornell University; Estados Unidos
Fil: Gabriel, Sofia I.. University of York; Reino Unido. Universidade de Lisboa; Portugal
Fil: Giménez, Mabel Dionisia. University of York; Reino Unido. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Biología Subtropical. Universidad Nacional de Misiones. Instituto de Biología Subtropical; Argentina
Fil: Panithanarak, Thadsin. Burapha University; Tailandia
Fil: Hauffe, Heidi C.. University of York; Reino Unido. Instituto Agrario San Michele All'adige Fondazione Edmund Mach. Centro Ricerca E Innovazione; Italia
Fil: Searle, Jeremy B.. Cornell University; Estados Unidos. University of York; Reino Unido
Materia
Chromosomal Hybrid Zone
Introgression
Microsatellites
Robertsonian Fusion
Speciation
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/39516
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/39516
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)Förster, Daniel W.Jones, Eleanor P.Jóhannesdóttir, FríðaGabriel, Sofia I.Giménez, Mabel DionisiaPanithanarak, ThadsinHauffe, Heidi C.Searle, Jeremy B.Chromosomal Hybrid ZoneIntrogressionMicrosatellitesRobertsonian FusionSpeciationhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The importance of chromosomal rearrangements for speciation can be inferred from studies of genetic exchange between hybridising chromosomal races within species. Reduced fertility or recombination suppression in karyotypic hybrids has the potential to maintain or promote genetic differentiation in genomic regions near rearrangement breakpoints. We studied genetic exchange between two hybridising groups of chromosomal races of house mouse in Upper Valtellina (Lombardy, Italy), using microsatellites. These groups differ by Robertsonian fusions and/or whole-arm reciprocal translocations such that F1 hybrids have a chain-of-five meiotic configuration. Previous studies showed genetic differentiation in two chromosomes in the chain-of-five (10 and 12) close to their centromeres (i.e. the rearrangement breakpoints); we have shown here that the centromeric regions of the other two chromosomes in the chain (2 and 8) are similarly differentiated. The internal chromosomes of the chain (8 and 12) show the greatest differentiation, which may reflect pairing and recombination properties of internal and external elements in a meiotic chain. Importantly, we found that centromeric regions of some non-rearranged chromosomes also showed genetic differentiation between the hybridising groups, indicating a complex interplay between chromosomal rearrangements and other parts of the genome in maintaining or promoting differentiation and potentially driving speciation between chromosomal races.Fil: Förster, Daniel W.. University of York; Reino Unido. Leibniz-Institute for Zoo and Wildlife Research; AlemaniaFil: Jones, Eleanor P.. University of York; Reino Unido. Fera Science; Reino UnidoFil: Jóhannesdóttir, Fríða. University of York; Reino Unido. Uppsala University; Suecia. Cornell University; Estados UnidosFil: Gabriel, Sofia I.. University of York; Reino Unido. Universidade de Lisboa; PortugalFil: Giménez, Mabel Dionisia. University of York; Reino Unido. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Biología Subtropical. Universidad Nacional de Misiones. Instituto de Biología Subtropical; ArgentinaFil: Panithanarak, Thadsin. Burapha University; TailandiaFil: Hauffe, Heidi C.. University of York; Reino Unido. Instituto Agrario San Michele All'adige Fondazione Edmund Mach. Centro Ricerca E Innovazione; ItaliaFil: Searle, Jeremy B.. Cornell University; Estados Unidos. University of York; Reino UnidoSpringer2016-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/39516Förster, Daniel W.; Jones, Eleanor P.; Jóhannesdóttir, Fríða; Gabriel, Sofia I.; Giménez, Mabel Dionisia; et al.; Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus); Springer; Chromosome Research; 24; 2; 5-2016; 271-2800967-38491573-6849CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1007/s10577-016-9520-1info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs10577-016-9520-1info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:44:16Zoai:ri.conicet.gov.ar:11336/39516instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:44:16.281CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)
title Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)
spellingShingle Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)
Förster, Daniel W.
Chromosomal Hybrid Zone
Introgression
Microsatellites
Robertsonian Fusion
Speciation
title_short Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)
title_full Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)
title_fullStr Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)
title_full_unstemmed Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)
title_sort Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus)
dc.creator.none.fl_str_mv Förster, Daniel W.
Jones, Eleanor P.
Jóhannesdóttir, Fríða
Gabriel, Sofia I.
Giménez, Mabel Dionisia
Panithanarak, Thadsin
Hauffe, Heidi C.
Searle, Jeremy B.
author Förster, Daniel W.
author_facet Förster, Daniel W.
Jones, Eleanor P.
Jóhannesdóttir, Fríða
Gabriel, Sofia I.
Giménez, Mabel Dionisia
Panithanarak, Thadsin
Hauffe, Heidi C.
Searle, Jeremy B.
author_role author
author2 Jones, Eleanor P.
Jóhannesdóttir, Fríða
Gabriel, Sofia I.
Giménez, Mabel Dionisia
Panithanarak, Thadsin
Hauffe, Heidi C.
Searle, Jeremy B.
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Chromosomal Hybrid Zone
Introgression
Microsatellites
Robertsonian Fusion
Speciation
topic Chromosomal Hybrid Zone
Introgression
Microsatellites
Robertsonian Fusion
Speciation
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The importance of chromosomal rearrangements for speciation can be inferred from studies of genetic exchange between hybridising chromosomal races within species. Reduced fertility or recombination suppression in karyotypic hybrids has the potential to maintain or promote genetic differentiation in genomic regions near rearrangement breakpoints. We studied genetic exchange between two hybridising groups of chromosomal races of house mouse in Upper Valtellina (Lombardy, Italy), using microsatellites. These groups differ by Robertsonian fusions and/or whole-arm reciprocal translocations such that F1 hybrids have a chain-of-five meiotic configuration. Previous studies showed genetic differentiation in two chromosomes in the chain-of-five (10 and 12) close to their centromeres (i.e. the rearrangement breakpoints); we have shown here that the centromeric regions of the other two chromosomes in the chain (2 and 8) are similarly differentiated. The internal chromosomes of the chain (8 and 12) show the greatest differentiation, which may reflect pairing and recombination properties of internal and external elements in a meiotic chain. Importantly, we found that centromeric regions of some non-rearranged chromosomes also showed genetic differentiation between the hybridising groups, indicating a complex interplay between chromosomal rearrangements and other parts of the genome in maintaining or promoting differentiation and potentially driving speciation between chromosomal races.
Fil: Förster, Daniel W.. University of York; Reino Unido. Leibniz-Institute for Zoo and Wildlife Research; Alemania
Fil: Jones, Eleanor P.. University of York; Reino Unido. Fera Science; Reino Unido
Fil: Jóhannesdóttir, Fríða. University of York; Reino Unido. Uppsala University; Suecia. Cornell University; Estados Unidos
Fil: Gabriel, Sofia I.. University of York; Reino Unido. Universidade de Lisboa; Portugal
Fil: Giménez, Mabel Dionisia. University of York; Reino Unido. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Biología Subtropical. Universidad Nacional de Misiones. Instituto de Biología Subtropical; Argentina
Fil: Panithanarak, Thadsin. Burapha University; Tailandia
Fil: Hauffe, Heidi C.. University of York; Reino Unido. Instituto Agrario San Michele All'adige Fondazione Edmund Mach. Centro Ricerca E Innovazione; Italia
Fil: Searle, Jeremy B.. Cornell University; Estados Unidos. University of York; Reino Unido
description The importance of chromosomal rearrangements for speciation can be inferred from studies of genetic exchange between hybridising chromosomal races within species. Reduced fertility or recombination suppression in karyotypic hybrids has the potential to maintain or promote genetic differentiation in genomic regions near rearrangement breakpoints. We studied genetic exchange between two hybridising groups of chromosomal races of house mouse in Upper Valtellina (Lombardy, Italy), using microsatellites. These groups differ by Robertsonian fusions and/or whole-arm reciprocal translocations such that F1 hybrids have a chain-of-five meiotic configuration. Previous studies showed genetic differentiation in two chromosomes in the chain-of-five (10 and 12) close to their centromeres (i.e. the rearrangement breakpoints); we have shown here that the centromeric regions of the other two chromosomes in the chain (2 and 8) are similarly differentiated. The internal chromosomes of the chain (8 and 12) show the greatest differentiation, which may reflect pairing and recombination properties of internal and external elements in a meiotic chain. Importantly, we found that centromeric regions of some non-rearranged chromosomes also showed genetic differentiation between the hybridising groups, indicating a complex interplay between chromosomal rearrangements and other parts of the genome in maintaining or promoting differentiation and potentially driving speciation between chromosomal races.
publishDate 2016
dc.date.none.fl_str_mv 2016-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/39516
Förster, Daniel W.; Jones, Eleanor P.; Jóhannesdóttir, Fríða; Gabriel, Sofia I.; Giménez, Mabel Dionisia; et al.; Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus); Springer; Chromosome Research; 24; 2; 5-2016; 271-280
0967-3849
1573-6849
CONICET Digital
CONICET
url http://hdl.handle.net/11336/39516
identifier_str_mv Förster, Daniel W.; Jones, Eleanor P.; Jóhannesdóttir, Fríða; Gabriel, Sofia I.; Giménez, Mabel Dionisia; et al.; Genetic differentiation within and away from the chromosomal rearrangements characterising hybridising chromosomal races of the western house mouse (Mus musculus domesticus); Springer; Chromosome Research; 24; 2; 5-2016; 271-280
0967-3849
1573-6849
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1007/s10577-016-9520-1
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs10577-016-9520-1
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.885934

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