Nonalcoholic fatty liver disease: biomarkers as diagnostic tools for liver damage assessment in adult patients from Argentina

Autores
Bertot, Gustavo
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Fil: Bertot, Gustavo. Instituto Universitario de Ciencias de la Salud. Fundación Barceló; Argentina..
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease whose prevalence has been increasing constantly and linked to the global obesity epidemic. The NAFLD histologic spectrum ranges from simple steatosis to nonalcoholic steatohepatitis (NASH), which can progress to cirrhosis and hepatocellular carcinoma. Liver biopsy is the only reliable means to diagnose and stage NASH, but its invasive nature limits its use. Therefore, the prediction of hepatic injury by means of the development of new noninvasive tests represents a growing medical need. Our aim was to evaluate matrix deposition and cell-death markers, which correlate with liver injury in an NAFLD patient cohort.
Materia
ARTICULO
METABOLISMO
HIGADO GRASO
Nivel de accesibilidad
acceso abierto
Condiciones de uso
Repositorio
Repositorio Institucional (Fundacion Barceló)
Institución
Fundación H. A. Barceló
OAI Identificador
oai:fbarcelo:snrd:HASH01206b55572e1e6592587e17
Acceder
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oai_identifier_str oai:fbarcelo:snrd:HASH01206b55572e1e6592587e17
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network_name_str Repositorio Institucional (Fundacion Barceló)
spelling Nonalcoholic fatty liver disease: biomarkers as diagnostic tools for liver damage assessment in adult patients from ArgentinaBertot, GustavoARTICULOMETABOLISMOHIGADO GRASOFil: Bertot, Gustavo. Instituto Universitario de Ciencias de la Salud. Fundación Barceló; Argentina..Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease whose prevalence has been increasing constantly and linked to the global obesity epidemic. The NAFLD histologic spectrum ranges from simple steatosis to nonalcoholic steatohepatitis (NASH), which can progress to cirrhosis and hepatocellular carcinoma. Liver biopsy is the only reliable means to diagnose and stage NASH, but its invasive nature limits its use. Therefore, the prediction of hepatic injury by means of the development of new noninvasive tests represents a growing medical need. Our aim was to evaluate matrix deposition and cell-death markers, which correlate with liver injury in an NAFLD patient cohort.European Journal of Gastroenterology & Hepatology 2018. 30(6)2020-02-27info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://repositorio.barcelo.edu.ar/greenstone/collect/snrd/index/assoc/HASH0120.dir/BRC_76_MED_BA.pdfenginfo:eu-repo/semantics/openAccessreponame:Repositorio Institucional (Fundacion Barceló)instname:Fundación H. A. Barceló2025-09-18T10:48:55Zoai:fbarcelo:snrd:HASH01206b55572e1e6592587e17instacron:BARCELOInstitucionalhttp://repositorio.barcelo.edu.ar/greenstone/cgi-bin/library.cgiUniversidad privadaNo correspondehttp://repositorio.barcelo.edu.ar/greenstone/cgi-bin/oaiserver.cgilrodriguezares@barcelo.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:a2025-09-18 10:48:56.108Repositorio Institucional (Fundacion Barceló) - Fundación H. A. Barcelófalse
dc.title.none.fl_str_mv Nonalcoholic fatty liver disease: biomarkers as diagnostic tools for liver damage assessment in adult patients from Argentina
title Nonalcoholic fatty liver disease: biomarkers as diagnostic tools for liver damage assessment in adult patients from Argentina
spellingShingle Nonalcoholic fatty liver disease: biomarkers as diagnostic tools for liver damage assessment in adult patients from Argentina
Bertot, Gustavo
ARTICULO
METABOLISMO
HIGADO GRASO
title_short Nonalcoholic fatty liver disease: biomarkers as diagnostic tools for liver damage assessment in adult patients from Argentina
title_full Nonalcoholic fatty liver disease: biomarkers as diagnostic tools for liver damage assessment in adult patients from Argentina
title_fullStr Nonalcoholic fatty liver disease: biomarkers as diagnostic tools for liver damage assessment in adult patients from Argentina
title_full_unstemmed Nonalcoholic fatty liver disease: biomarkers as diagnostic tools for liver damage assessment in adult patients from Argentina
title_sort Nonalcoholic fatty liver disease: biomarkers as diagnostic tools for liver damage assessment in adult patients from Argentina
dc.creator.none.fl_str_mv Bertot, Gustavo
author Bertot, Gustavo
author_facet Bertot, Gustavo
author_role author
dc.subject.none.fl_str_mv ARTICULO
METABOLISMO
HIGADO GRASO
topic ARTICULO
METABOLISMO
HIGADO GRASO
dc.description.none.fl_txt_mv Fil: Bertot, Gustavo. Instituto Universitario de Ciencias de la Salud. Fundación Barceló; Argentina..
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease whose prevalence has been increasing constantly and linked to the global obesity epidemic. The NAFLD histologic spectrum ranges from simple steatosis to nonalcoholic steatohepatitis (NASH), which can progress to cirrhosis and hepatocellular carcinoma. Liver biopsy is the only reliable means to diagnose and stage NASH, but its invasive nature limits its use. Therefore, the prediction of hepatic injury by means of the development of new noninvasive tests represents a growing medical need. Our aim was to evaluate matrix deposition and cell-death markers, which correlate with liver injury in an NAFLD patient cohort.
description Fil: Bertot, Gustavo. Instituto Universitario de Ciencias de la Salud. Fundación Barceló; Argentina..
publishDate 2020
dc.date.none.fl_str_mv 2020-02-27
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://repositorio.barcelo.edu.ar/greenstone/collect/snrd/index/assoc/HASH0120.dir/BRC_76_MED_BA.pdf
url http://repositorio.barcelo.edu.ar/greenstone/collect/snrd/index/assoc/HASH0120.dir/BRC_76_MED_BA.pdf
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv European Journal of Gastroenterology & Hepatology 2018. 30(6)
publisher.none.fl_str_mv European Journal of Gastroenterology & Hepatology 2018. 30(6)
dc.source.none.fl_str_mv reponame:Repositorio Institucional (Fundacion Barceló)
instname:Fundación H. A. Barceló
reponame_str Repositorio Institucional (Fundacion Barceló)
collection Repositorio Institucional (Fundacion Barceló)
instname_str Fundación H. A. Barceló
repository.name.fl_str_mv Repositorio Institucional (Fundacion Barceló) - Fundación H. A. Barceló
repository.mail.fl_str_mv lrodriguezares@barcelo.edu.ar
_version_ 1843611758499987456
score 13.070432

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