Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina

Autores
Bella, Santiago Rafael; Llugdar, José Roberto; Biagi Bistoni, Marta Inés; Pellicioni, Patricia; Lerda, Daniel Enrique; Labrador, Jorge; Fernández Cruz, G.; Martins, C.
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión aceptada
Descripción
The discovery of BRCA1 and BRCA2 genes has led to the introduction of increasingly sophisticated genetic tests to measure the risk of hereditary breast cancer, among other things. The aim of this study was to determine the prevalence of the mutation in 24 women from Córdoba with breast / ovarian cancer (BC / OC) and with at least two relatives with breast cancer. Although there are recurrent mutations, which appear repeatedly in unrelated families, with highest prevalence as in the Jewish ethnicity, this is the first study on the population of the province of Córdoba, Argentina.
Fil: Lerda, Daniel Enrique. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina
Fil: Bella, Santiago Rafael. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina
Fil: Biagi Bistoni, Marta Inés. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina
Fuente
Bella, Santiago Rafael, Llugdar, José Roberto, Biagi Bistoni, Marta Inés, Pellicioni, Patricia, Lerda, Daniel Enrique ORCID: https://orcid.org/0000-0002-1257-0954 , Labrador, Jorge, Fernández Cruz, G. and Martins, C. (2015) Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina. ARC Journal of Cancer Science (AJCS), 1 (1). pp. 11-16. ISSN 2455-6009
Materia
R Medicina (General)
RC0254 Neoplasias. Los tumores. Oncología (incluyendo cáncer)
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
Repositorio
Producción Académica (UCC)
Institución
Universidad Católica de Córdoba
OAI Identificador
oai:pa.bibdigital.uccor.edu.ar:1466
Acceder
id PAUCC_324b4dec78c669b75b69247f56ca06a5
oai_identifier_str oai:pa.bibdigital.uccor.edu.ar:1466
network_acronym_str PAUCC
repository_id_str 2718
network_name_str Producción Académica (UCC)
spelling Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, ArgentinaBella, Santiago RafaelLlugdar, José RobertoBiagi Bistoni, Marta InésPellicioni, PatriciaLerda, Daniel EnriqueLabrador, JorgeFernández Cruz, G.Martins, C.R Medicina (General)RC0254 Neoplasias. Los tumores. Oncología (incluyendo cáncer)The discovery of BRCA1 and BRCA2 genes has led to the introduction of increasingly sophisticated genetic tests to measure the risk of hereditary breast cancer, among other things. The aim of this study was to determine the prevalence of the mutation in 24 women from Córdoba with breast / ovarian cancer (BC / OC) and with at least two relatives with breast cancer. Although there are recurrent mutations, which appear repeatedly in unrelated families, with highest prevalence as in the Jewish ethnicity, this is the first study on the population of the province of Córdoba, Argentina.Fil: Lerda, Daniel Enrique. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; ArgentinaFil: Bella, Santiago Rafael. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; ArgentinaFil: Biagi Bistoni, Marta Inés. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; ArgentinaAcademicians' Research Center2015-03-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://pa.bibdigital.ucc.edu.ar/1466/1/A_Lerda_Bella_Llugdar.pdf Bella, Santiago Rafael, Llugdar, José Roberto, Biagi Bistoni, Marta Inés, Pellicioni, Patricia, Lerda, Daniel Enrique ORCID: https://orcid.org/0000-0002-1257-0954 <https://orcid.org/0000-0002-1257-0954>, Labrador, Jorge, Fernández Cruz, G. and Martins, C. (2015) Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina. ARC Journal of Cancer Science (AJCS), 1 (1). pp. 11-16. ISSN 2455-6009 reponame:Producción Académica (UCC)instname:Universidad Católica de Córdobaenghttp://pa.bibdigital.ucc.edu.ar/1466/https://www.arcjournals.org/journal-of-cancer-scienceinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es2025-09-29T14:29:03Zoai:pa.bibdigital.uccor.edu.ar:1466instacron:UCCInstitucionalhttp://pa.bibdigital.uccor.edu.ar/Universidad privadaNo correspondehttp://pa.bibdigital.uccor.edu.ar/cgi/oai2bibdir@uccor.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:27182025-09-29 14:29:04.168Producción Académica (UCC) - Universidad Católica de Córdobafalse
dc.title.none.fl_str_mv Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina
title Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina
spellingShingle Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina
Bella, Santiago Rafael
R Medicina (General)
RC0254 Neoplasias. Los tumores. Oncología (incluyendo cáncer)
title_short Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina
title_full Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina
title_fullStr Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina
title_full_unstemmed Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina
title_sort Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina
dc.creator.none.fl_str_mv Bella, Santiago Rafael
Llugdar, José Roberto
Biagi Bistoni, Marta Inés
Pellicioni, Patricia
Lerda, Daniel Enrique
Labrador, Jorge
Fernández Cruz, G.
Martins, C.
author Bella, Santiago Rafael
author_facet Bella, Santiago Rafael
Llugdar, José Roberto
Biagi Bistoni, Marta Inés
Pellicioni, Patricia
Lerda, Daniel Enrique
Labrador, Jorge
Fernández Cruz, G.
Martins, C.
author_role author
author2 Llugdar, José Roberto
Biagi Bistoni, Marta Inés
Pellicioni, Patricia
Lerda, Daniel Enrique
Labrador, Jorge
Fernández Cruz, G.
Martins, C.
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv R Medicina (General)
RC0254 Neoplasias. Los tumores. Oncología (incluyendo cáncer)
topic R Medicina (General)
RC0254 Neoplasias. Los tumores. Oncología (incluyendo cáncer)
dc.description.none.fl_txt_mv The discovery of BRCA1 and BRCA2 genes has led to the introduction of increasingly sophisticated genetic tests to measure the risk of hereditary breast cancer, among other things. The aim of this study was to determine the prevalence of the mutation in 24 women from Córdoba with breast / ovarian cancer (BC / OC) and with at least two relatives with breast cancer. Although there are recurrent mutations, which appear repeatedly in unrelated families, with highest prevalence as in the Jewish ethnicity, this is the first study on the population of the province of Córdoba, Argentina.
Fil: Lerda, Daniel Enrique. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina
Fil: Bella, Santiago Rafael. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina
Fil: Biagi Bistoni, Marta Inés. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina
description The discovery of BRCA1 and BRCA2 genes has led to the introduction of increasingly sophisticated genetic tests to measure the risk of hereditary breast cancer, among other things. The aim of this study was to determine the prevalence of the mutation in 24 women from Córdoba with breast / ovarian cancer (BC / OC) and with at least two relatives with breast cancer. Although there are recurrent mutations, which appear repeatedly in unrelated families, with highest prevalence as in the Jewish ethnicity, this is the first study on the population of the province of Córdoba, Argentina.
publishDate 2015
dc.date.none.fl_str_mv 2015-03-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://pa.bibdigital.ucc.edu.ar/1466/1/A_Lerda_Bella_Llugdar.pdf
url http://pa.bibdigital.ucc.edu.ar/1466/1/A_Lerda_Bella_Llugdar.pdf
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv http://pa.bibdigital.ucc.edu.ar/1466/
https://www.arcjournals.org/journal-of-cancer-science
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Academicians' Research Center
publisher.none.fl_str_mv Academicians' Research Center
dc.source.none.fl_str_mv Bella, Santiago Rafael, Llugdar, José Roberto, Biagi Bistoni, Marta Inés, Pellicioni, Patricia, Lerda, Daniel Enrique ORCID: https://orcid.org/0000-0002-1257-0954 <https://orcid.org/0000-0002-1257-0954>, Labrador, Jorge, Fernández Cruz, G. and Martins, C. (2015) Frequency of Mutations in Brca1 and Brca2 Genes in Women with Breast Cancer in Córdoba, Argentina. ARC Journal of Cancer Science (AJCS), 1 (1). pp. 11-16. ISSN 2455-6009
reponame:Producción Académica (UCC)
instname:Universidad Católica de Córdoba
reponame_str Producción Académica (UCC)
collection Producción Académica (UCC)
instname_str Universidad Católica de Córdoba
repository.name.fl_str_mv Producción Académica (UCC) - Universidad Católica de Córdoba
repository.mail.fl_str_mv bibdir@uccor.edu.ar
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score 12.559606

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