Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina : Clinical, histopathological and molecular studies

Autores
Sosa, Fabiana Evangelina; Anello, Melina; Ferreyra, Hebe del Valle; Medina Vallejo, Diego M.; Micheloud, Juan Francisco; Borsetti, Hugo M.; Hernández, Nancy; Florin-Christensen, Monica; Romero, Sandra Raquel
Año de publicación
2025
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Sarcoptic mange, caused by the mite Sarcoptes scabiei, is a highly contagious and potentially fatal skin disease that affects a wide range of mammals, including South American Camelids (SAC). Although the presence of mange has been described in vicuñas and llamas in northwestern Argentina, there are no previous records documenting its presence in guanacos (Lama guanicoe) of this region. We here describe a case of S. scabiei in a free-ranging guanaco in the Department of Tilcara, Jujuy Province. The animal presented alopecic, erythematous and hyperkeratotic lesions with abundant crusts in the ventral region of the body and limbs. Histopathology revealed periadnexal dermatitis with inflammatory infiltrate, severe hyperemia, orthokeratotic and parakeratotic epidermal hyperplasia, and stratum corneum thickening. The etiological agent was identified as S. scabiei by microscopic examination of adult mites. This result was confirmed by sequencing of a cytochrome oxidase subunit I gene fragment, that showed 100 % identity with sequences of isolates from SAC and other mammals. Genotyping of three mites isolated from different parts of the guanaco's body using a set of ten microsatellite markers indicated the infection with a single genetic variant that showed a similar profile to those found in S. scabiei isolates from vicuñas and llamas of the same region. However, genetic differences with guanaco isolates from midwestern Argentina were observed. This work presents the first record of sarcoptic mange in a guanaco in Jujuy Province and in the northwestern region of Argentina, as well as the molecular characterization of the etiological agent. The case highlights an uncertain scenario regarding the health situation of the guanaco population in this region, which is small, fragmented, and locally categorized as endangered. Epidemiological surveillance programs for guanacos and further research on the impact of sarcoptic mange on the conservation of this species are needed.
Instituto de Patobiología
Fil: Sosa, Fabiana Evangelina. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación y Desarrollo Tecnológico para la Agricultura Familiar Región NOA; Argentina
Fil: Sosa, Fabiana Evangelina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Anello, Melina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Anello, Melina. Universidad Nacional del Comahue. Instituto de Investigaciones en Biodiversidad y Medioambiente. Grupo de Investigaciones en Ecología y Fisiología de Fauna Silvestre; Argentina
Fil: Ferreyra, Hebe del Valle. Administracion de Parques Nacionales; Argentina
Fil: Medina Vallejo, Diego M. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación Animal del Chaco Semiárido. Área de Sanidad Animal; Argentina
Fil: Micheloud, Juan Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Micheloud, Juan Francisco. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación Animal del Chaco Semiárido. Área de Sanidad Animal; Argentina
Fil: Borsetti, Hugo M. Universidad Nacional de Jujuy. Instituto de Estudios Celulares, Genéticos y Moleculares (ICeGeM); Argentina
Fil: Hernández, Nancy. Universidad Nacional de Jujuy. Instituto de Estudios Celulares, Genéticos y Moleculares (ICeGeM); Argentina
Fil: Hernández, Nancy. Instituto de Ecorregiones Andinas (INECOA); Argentina
Fil: Hernández, Nancy. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Florin-Christensen, Monica. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Florin-Christensen, Monica. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología Veterinaria; Argentina
Fil: Romero, Sandra Raquel. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación y Desarrollo Tecnológico para la Agricultura Familiar Región NOA; Argentina
Fuente
International Journal for Parasitology: Parasites and Wildlife 27 : 101062 (August 2025)
Materia
Guanacos
Sarcoptic Mange
Mites
Genotyping
Resource Conservation
Lama guanicoe
Guanaco
Sarna Sarcóptica
Ácaros
Genotipado
Conservación de los Recursos
Argentina
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/22146
Acceder
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oai_identifier_str oai:localhost:20.500.12123/22146
network_acronym_str INTADig
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network_name_str INTA Digital (INTA)
spelling Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina : Clinical, histopathological and molecular studiesSosa, Fabiana EvangelinaAnello, MelinaFerreyra, Hebe del ValleMedina Vallejo, Diego M.Micheloud, Juan FranciscoBorsetti, Hugo M.Hernández, NancyFlorin-Christensen, MonicaRomero, Sandra RaquelGuanacosSarcoptic MangeMitesGenotypingResource ConservationLama guanicoeGuanacoSarna SarcópticaÁcarosGenotipadoConservación de los RecursosArgentinaSarcoptic mange, caused by the mite Sarcoptes scabiei, is a highly contagious and potentially fatal skin disease that affects a wide range of mammals, including South American Camelids (SAC). Although the presence of mange has been described in vicuñas and llamas in northwestern Argentina, there are no previous records documenting its presence in guanacos (Lama guanicoe) of this region. We here describe a case of S. scabiei in a free-ranging guanaco in the Department of Tilcara, Jujuy Province. The animal presented alopecic, erythematous and hyperkeratotic lesions with abundant crusts in the ventral region of the body and limbs. Histopathology revealed periadnexal dermatitis with inflammatory infiltrate, severe hyperemia, orthokeratotic and parakeratotic epidermal hyperplasia, and stratum corneum thickening. The etiological agent was identified as S. scabiei by microscopic examination of adult mites. This result was confirmed by sequencing of a cytochrome oxidase subunit I gene fragment, that showed 100 % identity with sequences of isolates from SAC and other mammals. Genotyping of three mites isolated from different parts of the guanaco's body using a set of ten microsatellite markers indicated the infection with a single genetic variant that showed a similar profile to those found in S. scabiei isolates from vicuñas and llamas of the same region. However, genetic differences with guanaco isolates from midwestern Argentina were observed. This work presents the first record of sarcoptic mange in a guanaco in Jujuy Province and in the northwestern region of Argentina, as well as the molecular characterization of the etiological agent. The case highlights an uncertain scenario regarding the health situation of the guanaco population in this region, which is small, fragmented, and locally categorized as endangered. Epidemiological surveillance programs for guanacos and further research on the impact of sarcoptic mange on the conservation of this species are needed.Instituto de PatobiologíaFil: Sosa, Fabiana Evangelina. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación y Desarrollo Tecnológico para la Agricultura Familiar Región NOA; ArgentinaFil: Sosa, Fabiana Evangelina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Anello, Melina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Anello, Melina. Universidad Nacional del Comahue. Instituto de Investigaciones en Biodiversidad y Medioambiente. Grupo de Investigaciones en Ecología y Fisiología de Fauna Silvestre; ArgentinaFil: Ferreyra, Hebe del Valle. Administracion de Parques Nacionales; ArgentinaFil: Medina Vallejo, Diego M. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación Animal del Chaco Semiárido. Área de Sanidad Animal; ArgentinaFil: Micheloud, Juan Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Micheloud, Juan Francisco. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación Animal del Chaco Semiárido. Área de Sanidad Animal; ArgentinaFil: Borsetti, Hugo M. Universidad Nacional de Jujuy. Instituto de Estudios Celulares, Genéticos y Moleculares (ICeGeM); ArgentinaFil: Hernández, Nancy. Universidad Nacional de Jujuy. Instituto de Estudios Celulares, Genéticos y Moleculares (ICeGeM); ArgentinaFil: Hernández, Nancy. Instituto de Ecorregiones Andinas (INECOA); ArgentinaFil: Hernández, Nancy. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Florin-Christensen, Monica. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Florin-Christensen, Monica. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología Veterinaria; ArgentinaFil: Romero, Sandra Raquel. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación y Desarrollo Tecnológico para la Agricultura Familiar Región NOA; ArgentinaElsevier2025-05-05T09:54:10Z2025-05-05T09:54:10Z2025-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/22146https://www.sciencedirect.com/science/article/pii/S22132244250002762213-2244https://doi.org/10.1016/j.ijppaw.2025.101062International Journal for Parasitology: Parasites and Wildlife 27 : 101062 (August 2025)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repograntAgreement/INTA/2023-PD-L06-I114, Desarrollo y aplicación de métodos diagnósticos y epidemiológicos para la producción pecuaria sustentable y agroalimentaria en humanos con foco en Una Saludinfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)2025-10-23T11:19:30Zoai:localhost:20.500.12123/22146instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-10-23 11:19:31.037INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina : Clinical, histopathological and molecular studies
title Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina : Clinical, histopathological and molecular studies
spellingShingle Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina : Clinical, histopathological and molecular studies
Sosa, Fabiana Evangelina
Guanacos
Sarcoptic Mange
Mites
Genotyping
Resource Conservation
Lama guanicoe
Guanaco
Sarna Sarcóptica
Ácaros
Genotipado
Conservación de los Recursos
Argentina
title_short Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina : Clinical, histopathological and molecular studies
title_full Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina : Clinical, histopathological and molecular studies
title_fullStr Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina : Clinical, histopathological and molecular studies
title_full_unstemmed Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina : Clinical, histopathological and molecular studies
title_sort Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina : Clinical, histopathological and molecular studies
dc.creator.none.fl_str_mv Sosa, Fabiana Evangelina
Anello, Melina
Ferreyra, Hebe del Valle
Medina Vallejo, Diego M.
Micheloud, Juan Francisco
Borsetti, Hugo M.
Hernández, Nancy
Florin-Christensen, Monica
Romero, Sandra Raquel
author Sosa, Fabiana Evangelina
author_facet Sosa, Fabiana Evangelina
Anello, Melina
Ferreyra, Hebe del Valle
Medina Vallejo, Diego M.
Micheloud, Juan Francisco
Borsetti, Hugo M.
Hernández, Nancy
Florin-Christensen, Monica
Romero, Sandra Raquel
author_role author
author2 Anello, Melina
Ferreyra, Hebe del Valle
Medina Vallejo, Diego M.
Micheloud, Juan Francisco
Borsetti, Hugo M.
Hernández, Nancy
Florin-Christensen, Monica
Romero, Sandra Raquel
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Guanacos
Sarcoptic Mange
Mites
Genotyping
Resource Conservation
Lama guanicoe
Guanaco
Sarna Sarcóptica
Ácaros
Genotipado
Conservación de los Recursos
Argentina
topic Guanacos
Sarcoptic Mange
Mites
Genotyping
Resource Conservation
Lama guanicoe
Guanaco
Sarna Sarcóptica
Ácaros
Genotipado
Conservación de los Recursos
Argentina
dc.description.none.fl_txt_mv Sarcoptic mange, caused by the mite Sarcoptes scabiei, is a highly contagious and potentially fatal skin disease that affects a wide range of mammals, including South American Camelids (SAC). Although the presence of mange has been described in vicuñas and llamas in northwestern Argentina, there are no previous records documenting its presence in guanacos (Lama guanicoe) of this region. We here describe a case of S. scabiei in a free-ranging guanaco in the Department of Tilcara, Jujuy Province. The animal presented alopecic, erythematous and hyperkeratotic lesions with abundant crusts in the ventral region of the body and limbs. Histopathology revealed periadnexal dermatitis with inflammatory infiltrate, severe hyperemia, orthokeratotic and parakeratotic epidermal hyperplasia, and stratum corneum thickening. The etiological agent was identified as S. scabiei by microscopic examination of adult mites. This result was confirmed by sequencing of a cytochrome oxidase subunit I gene fragment, that showed 100 % identity with sequences of isolates from SAC and other mammals. Genotyping of three mites isolated from different parts of the guanaco's body using a set of ten microsatellite markers indicated the infection with a single genetic variant that showed a similar profile to those found in S. scabiei isolates from vicuñas and llamas of the same region. However, genetic differences with guanaco isolates from midwestern Argentina were observed. This work presents the first record of sarcoptic mange in a guanaco in Jujuy Province and in the northwestern region of Argentina, as well as the molecular characterization of the etiological agent. The case highlights an uncertain scenario regarding the health situation of the guanaco population in this region, which is small, fragmented, and locally categorized as endangered. Epidemiological surveillance programs for guanacos and further research on the impact of sarcoptic mange on the conservation of this species are needed.
Instituto de Patobiología
Fil: Sosa, Fabiana Evangelina. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación y Desarrollo Tecnológico para la Agricultura Familiar Región NOA; Argentina
Fil: Sosa, Fabiana Evangelina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Anello, Melina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Anello, Melina. Universidad Nacional del Comahue. Instituto de Investigaciones en Biodiversidad y Medioambiente. Grupo de Investigaciones en Ecología y Fisiología de Fauna Silvestre; Argentina
Fil: Ferreyra, Hebe del Valle. Administracion de Parques Nacionales; Argentina
Fil: Medina Vallejo, Diego M. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación Animal del Chaco Semiárido. Área de Sanidad Animal; Argentina
Fil: Micheloud, Juan Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Micheloud, Juan Francisco. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación Animal del Chaco Semiárido. Área de Sanidad Animal; Argentina
Fil: Borsetti, Hugo M. Universidad Nacional de Jujuy. Instituto de Estudios Celulares, Genéticos y Moleculares (ICeGeM); Argentina
Fil: Hernández, Nancy. Universidad Nacional de Jujuy. Instituto de Estudios Celulares, Genéticos y Moleculares (ICeGeM); Argentina
Fil: Hernández, Nancy. Instituto de Ecorregiones Andinas (INECOA); Argentina
Fil: Hernández, Nancy. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Florin-Christensen, Monica. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Florin-Christensen, Monica. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología Veterinaria; Argentina
Fil: Romero, Sandra Raquel. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Investigación y Desarrollo Tecnológico para la Agricultura Familiar Región NOA; Argentina
description Sarcoptic mange, caused by the mite Sarcoptes scabiei, is a highly contagious and potentially fatal skin disease that affects a wide range of mammals, including South American Camelids (SAC). Although the presence of mange has been described in vicuñas and llamas in northwestern Argentina, there are no previous records documenting its presence in guanacos (Lama guanicoe) of this region. We here describe a case of S. scabiei in a free-ranging guanaco in the Department of Tilcara, Jujuy Province. The animal presented alopecic, erythematous and hyperkeratotic lesions with abundant crusts in the ventral region of the body and limbs. Histopathology revealed periadnexal dermatitis with inflammatory infiltrate, severe hyperemia, orthokeratotic and parakeratotic epidermal hyperplasia, and stratum corneum thickening. The etiological agent was identified as S. scabiei by microscopic examination of adult mites. This result was confirmed by sequencing of a cytochrome oxidase subunit I gene fragment, that showed 100 % identity with sequences of isolates from SAC and other mammals. Genotyping of three mites isolated from different parts of the guanaco's body using a set of ten microsatellite markers indicated the infection with a single genetic variant that showed a similar profile to those found in S. scabiei isolates from vicuñas and llamas of the same region. However, genetic differences with guanaco isolates from midwestern Argentina were observed. This work presents the first record of sarcoptic mange in a guanaco in Jujuy Province and in the northwestern region of Argentina, as well as the molecular characterization of the etiological agent. The case highlights an uncertain scenario regarding the health situation of the guanaco population in this region, which is small, fragmented, and locally categorized as endangered. Epidemiological surveillance programs for guanacos and further research on the impact of sarcoptic mange on the conservation of this species are needed.
publishDate 2025
dc.date.none.fl_str_mv 2025-05-05T09:54:10Z
2025-05-05T09:54:10Z
2025-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/22146
https://www.sciencedirect.com/science/article/pii/S2213224425000276
2213-2244
https://doi.org/10.1016/j.ijppaw.2025.101062
url http://hdl.handle.net/20.500.12123/22146
https://www.sciencedirect.com/science/article/pii/S2213224425000276
https://doi.org/10.1016/j.ijppaw.2025.101062
identifier_str_mv 2213-2244
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repograntAgreement/INTA/2023-PD-L06-I114, Desarrollo y aplicación de métodos diagnósticos y epidemiológicos para la producción pecuaria sustentable y agroalimentaria en humanos con foco en Una Salud
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv International Journal for Parasitology: Parasites and Wildlife 27 : 101062 (August 2025)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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