Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina: Clinical, histopathological and molecular studies

Autores
Sosa, Fabiana Evangelina; Anello, Melina; Ferreyra, Hebe del Valle; Medina, Diego M.; Micheloud, Juan Francisco; Borsetti, Hugo Mario; Hernández, Nancy Elizabeth; Florin Christensen, Mónica; Romero, Sandra R.
Año de publicación
2025
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Sarcoptic mange, caused by the mite Sarcoptes scabiei, is a highly contagious and potentially fatal skin disease that affects a wide range of mammals, including South American Camelids (SAC). Although the presence of mange has been described in vicuñas and llamas in northwestern Argentina, there are no previous records documenting its presence in guanacos (Lama guanicoe) of this region. We here describe a case of S. scabiei in a free-ranging guanaco in the Department of Tilcara, Jujuy Province. The animal presented alopecic, erythematous and hyperkeratotic lesions with abundant crusts in the ventral region of the body and limbs. Histopathology revealed periannexal dermatitis with inflammatory infiltrate, severe hyperemia, orthokeratotic and parakeratotic epidermal hyperplasia, and stratum corneum thickening. The etiological agent was identified as S. scabiei by microscopic examination of adult mites. This result was confirmed by sequencing of a cytochrome oxidase subunit I gene fragment, that showed 100% identity with sequences of isolates from SAC and other mammals. Genotyping of three mites isolated from different parts of the guanaco´s body using a set of ten microsatellite markers indicated the infection with a single genetic variant that showed a similar profile to those found in S. scabiei isolates from vicuñas and llamas of the same region. However, genetic differences with guanaco isolates from midwestern Argentina were observed. This work presents the first record of sarcoptic mange in a guanaco in Jujuy Province and in the northwestern region of Argentina, as well as the molecular characterization of the etiological agent. The case highlights an uncertain scenario regarding the health situation of the guanaco population in this region, which is small, fragmented, and locally categorized as endangered. Epidemiological surveillance programs for guanacos and further research on the impact of sarcoptic mange on the conservation of this species are needed.
Fil: Sosa, Fabiana Evangelina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnologia Agropecuaria. Centro de Investigacion y Desarrollo Tecnologico Para la Agricultura Familiar. Instituto de Investigacion y Desarrollo Tecnologico Para la Agricultura Familiar Region Noa.; Argentina
Fil: Anello, Melina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigaciones en Biodiversidad y Medioambiente. Universidad Nacional del Comahue. Centro Regional Universidad Bariloche. Instituto de Investigaciones en Biodiversidad y Medioambiente; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina
Fil: Ferreyra, Hebe del Valle. Administración de Parques Nacionales; Argentina
Fil: Medina, Diego M.. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigaciones Agropecuarias. Instituto de Investigación Animal del Chaco Semiárido; Argentina
Fil: Micheloud, Juan Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigaciones Agropecuarias. Instituto de Investigación Animal del Chaco Semiárido; Argentina
Fil: Borsetti, Hugo Mario. Universidad Nacional de Jujuy. Instituto de Estudios Celulares, Genéticos y Moleculares; Argentina
Fil: Hernández, Nancy Elizabeth. Universidad Nacional de Jujuy. Instituto de Ecorregiones Andinas. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Ecorregiones Andinas; Argentina. Universidad Nacional de Jujuy. Instituto de Estudios Celulares, Genéticos y Moleculares; Argentina
Fil: Florin Christensen, Mónica. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación En Ciencias Veterinarias y Agronómicas. Instituto de Patobiología Veterinaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Patobiología Veterinaria; Argentina
Fil: Romero, Sandra R.. Instituto Nacional de Tecnologia Agropecuaria. Centro de Investigacion y Desarrollo Tecnologico Para la Agricultura Familiar. Instituto de Investigacion y Desarrollo Tecnologico Para la Agricultura Familiar Region Noa.; Argentina
Materia
GUANACO
SARCOPTIC MANGE
MITES
GENOTYPING
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/281489

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spelling Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina: Clinical, histopathological and molecular studiesSosa, Fabiana EvangelinaAnello, MelinaFerreyra, Hebe del ValleMedina, Diego M.Micheloud, Juan FranciscoBorsetti, Hugo MarioHernández, Nancy ElizabethFlorin Christensen, MónicaRomero, Sandra R.GUANACOSARCOPTIC MANGEMITESGENOTYPINGhttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4Sarcoptic mange, caused by the mite Sarcoptes scabiei, is a highly contagious and potentially fatal skin disease that affects a wide range of mammals, including South American Camelids (SAC). Although the presence of mange has been described in vicuñas and llamas in northwestern Argentina, there are no previous records documenting its presence in guanacos (Lama guanicoe) of this region. We here describe a case of S. scabiei in a free-ranging guanaco in the Department of Tilcara, Jujuy Province. The animal presented alopecic, erythematous and hyperkeratotic lesions with abundant crusts in the ventral region of the body and limbs. Histopathology revealed periannexal dermatitis with inflammatory infiltrate, severe hyperemia, orthokeratotic and parakeratotic epidermal hyperplasia, and stratum corneum thickening. The etiological agent was identified as S. scabiei by microscopic examination of adult mites. This result was confirmed by sequencing of a cytochrome oxidase subunit I gene fragment, that showed 100% identity with sequences of isolates from SAC and other mammals. Genotyping of three mites isolated from different parts of the guanaco´s body using a set of ten microsatellite markers indicated the infection with a single genetic variant that showed a similar profile to those found in S. scabiei isolates from vicuñas and llamas of the same region. However, genetic differences with guanaco isolates from midwestern Argentina were observed. This work presents the first record of sarcoptic mange in a guanaco in Jujuy Province and in the northwestern region of Argentina, as well as the molecular characterization of the etiological agent. The case highlights an uncertain scenario regarding the health situation of the guanaco population in this region, which is small, fragmented, and locally categorized as endangered. Epidemiological surveillance programs for guanacos and further research on the impact of sarcoptic mange on the conservation of this species are needed.Fil: Sosa, Fabiana Evangelina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnologia Agropecuaria. Centro de Investigacion y Desarrollo Tecnologico Para la Agricultura Familiar. Instituto de Investigacion y Desarrollo Tecnologico Para la Agricultura Familiar Region Noa.; ArgentinaFil: Anello, Melina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigaciones en Biodiversidad y Medioambiente. Universidad Nacional del Comahue. Centro Regional Universidad Bariloche. Instituto de Investigaciones en Biodiversidad y Medioambiente; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; ArgentinaFil: Ferreyra, Hebe del Valle. Administración de Parques Nacionales; ArgentinaFil: Medina, Diego M.. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigaciones Agropecuarias. Instituto de Investigación Animal del Chaco Semiárido; ArgentinaFil: Micheloud, Juan Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigaciones Agropecuarias. Instituto de Investigación Animal del Chaco Semiárido; ArgentinaFil: Borsetti, Hugo Mario. Universidad Nacional de Jujuy. Instituto de Estudios Celulares, Genéticos y Moleculares; ArgentinaFil: Hernández, Nancy Elizabeth. Universidad Nacional de Jujuy. Instituto de Ecorregiones Andinas. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Ecorregiones Andinas; Argentina. Universidad Nacional de Jujuy. Instituto de Estudios Celulares, Genéticos y Moleculares; ArgentinaFil: Florin Christensen, Mónica. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación En Ciencias Veterinarias y Agronómicas. Instituto de Patobiología Veterinaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Patobiología Veterinaria; ArgentinaFil: Romero, Sandra R.. Instituto Nacional de Tecnologia Agropecuaria. Centro de Investigacion y Desarrollo Tecnologico Para la Agricultura Familiar. Instituto de Investigacion y Desarrollo Tecnologico Para la Agricultura Familiar Region Noa.; ArgentinaElsevier2025-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/281489Sosa, Fabiana Evangelina; Anello, Melina; Ferreyra, Hebe del Valle; Medina, Diego M.; Micheloud, Juan Francisco; et al.; Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina: Clinical, histopathological and molecular studies; Elsevier; International Journal for Parasitology: Parasites and Wildlife; 27; 8-2025; 1-62213-2244CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S2213224425000276info:eu-repo/semantics/altIdentifier/doi/10.1016/j.ijppaw.2025.101062info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2026-03-31T15:14:34Zoai:ri.conicet.gov.ar:11336/281489instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982026-03-31 15:14:34.531CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina: Clinical, histopathological and molecular studies
title Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina: Clinical, histopathological and molecular studies
spellingShingle Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina: Clinical, histopathological and molecular studies
Sosa, Fabiana Evangelina
GUANACO
SARCOPTIC MANGE
MITES
GENOTYPING
title_short Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina: Clinical, histopathological and molecular studies
title_full Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina: Clinical, histopathological and molecular studies
title_fullStr Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina: Clinical, histopathological and molecular studies
title_full_unstemmed Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina: Clinical, histopathological and molecular studies
title_sort Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina: Clinical, histopathological and molecular studies
dc.creator.none.fl_str_mv Sosa, Fabiana Evangelina
Anello, Melina
Ferreyra, Hebe del Valle
Medina, Diego M.
Micheloud, Juan Francisco
Borsetti, Hugo Mario
Hernández, Nancy Elizabeth
Florin Christensen, Mónica
Romero, Sandra R.
author Sosa, Fabiana Evangelina
author_facet Sosa, Fabiana Evangelina
Anello, Melina
Ferreyra, Hebe del Valle
Medina, Diego M.
Micheloud, Juan Francisco
Borsetti, Hugo Mario
Hernández, Nancy Elizabeth
Florin Christensen, Mónica
Romero, Sandra R.
author_role author
author2 Anello, Melina
Ferreyra, Hebe del Valle
Medina, Diego M.
Micheloud, Juan Francisco
Borsetti, Hugo Mario
Hernández, Nancy Elizabeth
Florin Christensen, Mónica
Romero, Sandra R.
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv GUANACO
SARCOPTIC MANGE
MITES
GENOTYPING
topic GUANACO
SARCOPTIC MANGE
MITES
GENOTYPING
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv Sarcoptic mange, caused by the mite Sarcoptes scabiei, is a highly contagious and potentially fatal skin disease that affects a wide range of mammals, including South American Camelids (SAC). Although the presence of mange has been described in vicuñas and llamas in northwestern Argentina, there are no previous records documenting its presence in guanacos (Lama guanicoe) of this region. We here describe a case of S. scabiei in a free-ranging guanaco in the Department of Tilcara, Jujuy Province. The animal presented alopecic, erythematous and hyperkeratotic lesions with abundant crusts in the ventral region of the body and limbs. Histopathology revealed periannexal dermatitis with inflammatory infiltrate, severe hyperemia, orthokeratotic and parakeratotic epidermal hyperplasia, and stratum corneum thickening. The etiological agent was identified as S. scabiei by microscopic examination of adult mites. This result was confirmed by sequencing of a cytochrome oxidase subunit I gene fragment, that showed 100% identity with sequences of isolates from SAC and other mammals. Genotyping of three mites isolated from different parts of the guanaco´s body using a set of ten microsatellite markers indicated the infection with a single genetic variant that showed a similar profile to those found in S. scabiei isolates from vicuñas and llamas of the same region. However, genetic differences with guanaco isolates from midwestern Argentina were observed. This work presents the first record of sarcoptic mange in a guanaco in Jujuy Province and in the northwestern region of Argentina, as well as the molecular characterization of the etiological agent. The case highlights an uncertain scenario regarding the health situation of the guanaco population in this region, which is small, fragmented, and locally categorized as endangered. Epidemiological surveillance programs for guanacos and further research on the impact of sarcoptic mange on the conservation of this species are needed.
Fil: Sosa, Fabiana Evangelina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnologia Agropecuaria. Centro de Investigacion y Desarrollo Tecnologico Para la Agricultura Familiar. Instituto de Investigacion y Desarrollo Tecnologico Para la Agricultura Familiar Region Noa.; Argentina
Fil: Anello, Melina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigaciones en Biodiversidad y Medioambiente. Universidad Nacional del Comahue. Centro Regional Universidad Bariloche. Instituto de Investigaciones en Biodiversidad y Medioambiente; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina
Fil: Ferreyra, Hebe del Valle. Administración de Parques Nacionales; Argentina
Fil: Medina, Diego M.. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigaciones Agropecuarias. Instituto de Investigación Animal del Chaco Semiárido; Argentina
Fil: Micheloud, Juan Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigaciones Agropecuarias. Instituto de Investigación Animal del Chaco Semiárido; Argentina
Fil: Borsetti, Hugo Mario. Universidad Nacional de Jujuy. Instituto de Estudios Celulares, Genéticos y Moleculares; Argentina
Fil: Hernández, Nancy Elizabeth. Universidad Nacional de Jujuy. Instituto de Ecorregiones Andinas. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Ecorregiones Andinas; Argentina. Universidad Nacional de Jujuy. Instituto de Estudios Celulares, Genéticos y Moleculares; Argentina
Fil: Florin Christensen, Mónica. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación En Ciencias Veterinarias y Agronómicas. Instituto de Patobiología Veterinaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Patobiología Veterinaria; Argentina
Fil: Romero, Sandra R.. Instituto Nacional de Tecnologia Agropecuaria. Centro de Investigacion y Desarrollo Tecnologico Para la Agricultura Familiar. Instituto de Investigacion y Desarrollo Tecnologico Para la Agricultura Familiar Region Noa.; Argentina
description Sarcoptic mange, caused by the mite Sarcoptes scabiei, is a highly contagious and potentially fatal skin disease that affects a wide range of mammals, including South American Camelids (SAC). Although the presence of mange has been described in vicuñas and llamas in northwestern Argentina, there are no previous records documenting its presence in guanacos (Lama guanicoe) of this region. We here describe a case of S. scabiei in a free-ranging guanaco in the Department of Tilcara, Jujuy Province. The animal presented alopecic, erythematous and hyperkeratotic lesions with abundant crusts in the ventral region of the body and limbs. Histopathology revealed periannexal dermatitis with inflammatory infiltrate, severe hyperemia, orthokeratotic and parakeratotic epidermal hyperplasia, and stratum corneum thickening. The etiological agent was identified as S. scabiei by microscopic examination of adult mites. This result was confirmed by sequencing of a cytochrome oxidase subunit I gene fragment, that showed 100% identity with sequences of isolates from SAC and other mammals. Genotyping of three mites isolated from different parts of the guanaco´s body using a set of ten microsatellite markers indicated the infection with a single genetic variant that showed a similar profile to those found in S. scabiei isolates from vicuñas and llamas of the same region. However, genetic differences with guanaco isolates from midwestern Argentina were observed. This work presents the first record of sarcoptic mange in a guanaco in Jujuy Province and in the northwestern region of Argentina, as well as the molecular characterization of the etiological agent. The case highlights an uncertain scenario regarding the health situation of the guanaco population in this region, which is small, fragmented, and locally categorized as endangered. Epidemiological surveillance programs for guanacos and further research on the impact of sarcoptic mange on the conservation of this species are needed.
publishDate 2025
dc.date.none.fl_str_mv 2025-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/281489
Sosa, Fabiana Evangelina; Anello, Melina; Ferreyra, Hebe del Valle; Medina, Diego M.; Micheloud, Juan Francisco; et al.; Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina: Clinical, histopathological and molecular studies; Elsevier; International Journal for Parasitology: Parasites and Wildlife; 27; 8-2025; 1-6
2213-2244
CONICET Digital
CONICET
url http://hdl.handle.net/11336/281489
identifier_str_mv Sosa, Fabiana Evangelina; Anello, Melina; Ferreyra, Hebe del Valle; Medina, Diego M.; Micheloud, Juan Francisco; et al.; Sarcoptic mange in a guanaco (Lama guanicoe) of northwestern Argentina: Clinical, histopathological and molecular studies; Elsevier; International Journal for Parasitology: Parasites and Wildlife; 27; 8-2025; 1-6
2213-2244
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
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info:eu-repo/semantics/altIdentifier/doi/10.1016/j.ijppaw.2025.101062
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publisher.none.fl_str_mv Elsevier
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