Effect of protein restriction of bovine dams during late gestation on offspring postnatal growth, glucose-insulin metabolism and IGF-1 concentration

Autores
Maresca, Sebastian; Lopez Valiente, Sebastian; Rodriguez, Alejandro Martin; Long, Nathan M.; Pavan, Enrique; Quintans, Graciela I.
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The objective of this study was determine whether the amount of protein provided to cows during late gestation would affect postnatal growth and lead to changes on glucose, insulin and insulin-like growth factor concentrations. At 134 d prepartum, 68 multiparous Angus cows were blocked by BW and expected calving date and randomly assigned to low protein level (LP, 6% CP) or high protein level (HP, 12% CP) and were allotted in 12 pens per treatment. At calving, cows were managed together on improved pastures until weaning. Calves were weighed and body measurements were recorded at birth. Blood samples were taken at birth and each 30 d until weaning at 180 d of age. Body weight at birth on HP progeny tended to be great than LP progeny (P = 0.06). At birth, calves from LP dams had greater head circumference (P 〈 0.01), heart girth (P = 0.01) and cannon bone circumference (P = 0.02). However, head circumference /birth BW ratio (P = 0.04), heart girth /birth BW ratio (P = 0.01), body length /birth BW ratio (P = 0.05) and height /birth BW ratio (P = 0.01) was greater on LP calves. Body mass index was greater in HP calves (P = 0.04). No differences were found on BW of calves at weaning, adjusted 205d BW and ADG during lactation (P 〉 0.10). Glucose concentrations were greater on LP calves than HP calves from birth to weaning (81.0 ± 1.5 vs. 76.4 ± 1.2 mg/dl; P 〈 0.001) without any change in insulin concentrations during preweaning growth (LP = 1.61 ± 0.04 ng/ml; HP = 1.61 ± 0.04 ng/ml; P 〉 0.10). Insulin-like growth factor concentrations was less on LP calves at birth (P 〈 0.05) and similar to HP calves during postnatal growth (P 〉 0.10). These data demonstrate that low protein during late gestation in bovine dams may affect fetal growth with proportional increasing of head circumference and low body mass index. Level of protein compromised glucose regulation in early life and affected the IGF-I concentration of newborn calves.
EEA Cuenca del Salado
Fil: Maresca, Sebastian. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Cuenca del Salado; Argentina
Fil: Lopez Valiente, Sebastian. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Cuenca del Salado; Argentina
Fil: Rodriguez, Alejandro Martin. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Cuenca del Salado; Argentina
Fil: Long, Nathan M. Clemson University. Department of Animal and Veterinary Sciences; Estados Unidos
Fil: Pavan, Enrique. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina
Fil: Quintans, Graciela I. Instituto Nacional de Investigación Agropecuaria (INIA); Uruguay
Fuente
Livestock science 212 : 120-126. (June 2018)
Materia
Ganado Bovino
Gestación
Malnutrición
Glucosa
Cattle
Pregnancy
Malnutrition
Glucose
Nivel de accesibilidad
acceso restringido
Condiciones de uso
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/2567
Acceder
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oai_identifier_str oai:localhost:20.500.12123/2567
network_acronym_str INTADig
repository_id_str l
network_name_str INTA Digital (INTA)
spelling Effect of protein restriction of bovine dams during late gestation on offspring postnatal growth, glucose-insulin metabolism and IGF-1 concentrationMaresca, SebastianLopez Valiente, SebastianRodriguez, Alejandro MartinLong, Nathan M.Pavan, EnriqueQuintans, Graciela I.Ganado BovinoGestaciónMalnutriciónGlucosaCattlePregnancyMalnutritionGlucoseThe objective of this study was determine whether the amount of protein provided to cows during late gestation would affect postnatal growth and lead to changes on glucose, insulin and insulin-like growth factor concentrations. At 134 d prepartum, 68 multiparous Angus cows were blocked by BW and expected calving date and randomly assigned to low protein level (LP, 6% CP) or high protein level (HP, 12% CP) and were allotted in 12 pens per treatment. At calving, cows were managed together on improved pastures until weaning. Calves were weighed and body measurements were recorded at birth. Blood samples were taken at birth and each 30 d until weaning at 180 d of age. Body weight at birth on HP progeny tended to be great than LP progeny (P = 0.06). At birth, calves from LP dams had greater head circumference (P 〈 0.01), heart girth (P = 0.01) and cannon bone circumference (P = 0.02). However, head circumference /birth BW ratio (P = 0.04), heart girth /birth BW ratio (P = 0.01), body length /birth BW ratio (P = 0.05) and height /birth BW ratio (P = 0.01) was greater on LP calves. Body mass index was greater in HP calves (P = 0.04). No differences were found on BW of calves at weaning, adjusted 205d BW and ADG during lactation (P 〉 0.10). Glucose concentrations were greater on LP calves than HP calves from birth to weaning (81.0 ± 1.5 vs. 76.4 ± 1.2 mg/dl; P 〈 0.001) without any change in insulin concentrations during preweaning growth (LP = 1.61 ± 0.04 ng/ml; HP = 1.61 ± 0.04 ng/ml; P 〉 0.10). Insulin-like growth factor concentrations was less on LP calves at birth (P 〈 0.05) and similar to HP calves during postnatal growth (P 〉 0.10). These data demonstrate that low protein during late gestation in bovine dams may affect fetal growth with proportional increasing of head circumference and low body mass index. Level of protein compromised glucose regulation in early life and affected the IGF-I concentration of newborn calves.EEA Cuenca del SaladoFil: Maresca, Sebastian. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Cuenca del Salado; ArgentinaFil: Lopez Valiente, Sebastian. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Cuenca del Salado; ArgentinaFil: Rodriguez, Alejandro Martin. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Cuenca del Salado; ArgentinaFil: Long, Nathan M. Clemson University. Department of Animal and Veterinary Sciences; Estados UnidosFil: Pavan, Enrique. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; ArgentinaFil: Quintans, Graciela I. Instituto Nacional de Investigación Agropecuaria (INIA); Uruguay2018-06-07T14:42:58Z2018-06-07T14:42:58Z2018-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://www.sciencedirect.com/science/article/pii/S1871141318301057http://hdl.handle.net/20.500.12123/25671871-1413https://doi.org/10.1016/j.livsci.2018.04.009Livestock science 212 : 120-126. (June 2018)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repo/semantics/restrictedAccess2025-09-04T09:47:19Zoai:localhost:20.500.12123/2567instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-09-04 09:47:20.203INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Effect of protein restriction of bovine dams during late gestation on offspring postnatal growth, glucose-insulin metabolism and IGF-1 concentration
title Effect of protein restriction of bovine dams during late gestation on offspring postnatal growth, glucose-insulin metabolism and IGF-1 concentration
spellingShingle Effect of protein restriction of bovine dams during late gestation on offspring postnatal growth, glucose-insulin metabolism and IGF-1 concentration
Maresca, Sebastian
Ganado Bovino
Gestación
Malnutrición
Glucosa
Cattle
Pregnancy
Malnutrition
Glucose
title_short Effect of protein restriction of bovine dams during late gestation on offspring postnatal growth, glucose-insulin metabolism and IGF-1 concentration
title_full Effect of protein restriction of bovine dams during late gestation on offspring postnatal growth, glucose-insulin metabolism and IGF-1 concentration
title_fullStr Effect of protein restriction of bovine dams during late gestation on offspring postnatal growth, glucose-insulin metabolism and IGF-1 concentration
title_full_unstemmed Effect of protein restriction of bovine dams during late gestation on offspring postnatal growth, glucose-insulin metabolism and IGF-1 concentration
title_sort Effect of protein restriction of bovine dams during late gestation on offspring postnatal growth, glucose-insulin metabolism and IGF-1 concentration
dc.creator.none.fl_str_mv Maresca, Sebastian
Lopez Valiente, Sebastian
Rodriguez, Alejandro Martin
Long, Nathan M.
Pavan, Enrique
Quintans, Graciela I.
author Maresca, Sebastian
author_facet Maresca, Sebastian
Lopez Valiente, Sebastian
Rodriguez, Alejandro Martin
Long, Nathan M.
Pavan, Enrique
Quintans, Graciela I.
author_role author
author2 Lopez Valiente, Sebastian
Rodriguez, Alejandro Martin
Long, Nathan M.
Pavan, Enrique
Quintans, Graciela I.
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Ganado Bovino
Gestación
Malnutrición
Glucosa
Cattle
Pregnancy
Malnutrition
Glucose
topic Ganado Bovino
Gestación
Malnutrición
Glucosa
Cattle
Pregnancy
Malnutrition
Glucose
dc.description.none.fl_txt_mv The objective of this study was determine whether the amount of protein provided to cows during late gestation would affect postnatal growth and lead to changes on glucose, insulin and insulin-like growth factor concentrations. At 134 d prepartum, 68 multiparous Angus cows were blocked by BW and expected calving date and randomly assigned to low protein level (LP, 6% CP) or high protein level (HP, 12% CP) and were allotted in 12 pens per treatment. At calving, cows were managed together on improved pastures until weaning. Calves were weighed and body measurements were recorded at birth. Blood samples were taken at birth and each 30 d until weaning at 180 d of age. Body weight at birth on HP progeny tended to be great than LP progeny (P = 0.06). At birth, calves from LP dams had greater head circumference (P 〈 0.01), heart girth (P = 0.01) and cannon bone circumference (P = 0.02). However, head circumference /birth BW ratio (P = 0.04), heart girth /birth BW ratio (P = 0.01), body length /birth BW ratio (P = 0.05) and height /birth BW ratio (P = 0.01) was greater on LP calves. Body mass index was greater in HP calves (P = 0.04). No differences were found on BW of calves at weaning, adjusted 205d BW and ADG during lactation (P 〉 0.10). Glucose concentrations were greater on LP calves than HP calves from birth to weaning (81.0 ± 1.5 vs. 76.4 ± 1.2 mg/dl; P 〈 0.001) without any change in insulin concentrations during preweaning growth (LP = 1.61 ± 0.04 ng/ml; HP = 1.61 ± 0.04 ng/ml; P 〉 0.10). Insulin-like growth factor concentrations was less on LP calves at birth (P 〈 0.05) and similar to HP calves during postnatal growth (P 〉 0.10). These data demonstrate that low protein during late gestation in bovine dams may affect fetal growth with proportional increasing of head circumference and low body mass index. Level of protein compromised glucose regulation in early life and affected the IGF-I concentration of newborn calves.
EEA Cuenca del Salado
Fil: Maresca, Sebastian. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Cuenca del Salado; Argentina
Fil: Lopez Valiente, Sebastian. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Cuenca del Salado; Argentina
Fil: Rodriguez, Alejandro Martin. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Cuenca del Salado; Argentina
Fil: Long, Nathan M. Clemson University. Department of Animal and Veterinary Sciences; Estados Unidos
Fil: Pavan, Enrique. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina
Fil: Quintans, Graciela I. Instituto Nacional de Investigación Agropecuaria (INIA); Uruguay
description The objective of this study was determine whether the amount of protein provided to cows during late gestation would affect postnatal growth and lead to changes on glucose, insulin and insulin-like growth factor concentrations. At 134 d prepartum, 68 multiparous Angus cows were blocked by BW and expected calving date and randomly assigned to low protein level (LP, 6% CP) or high protein level (HP, 12% CP) and were allotted in 12 pens per treatment. At calving, cows were managed together on improved pastures until weaning. Calves were weighed and body measurements were recorded at birth. Blood samples were taken at birth and each 30 d until weaning at 180 d of age. Body weight at birth on HP progeny tended to be great than LP progeny (P = 0.06). At birth, calves from LP dams had greater head circumference (P 〈 0.01), heart girth (P = 0.01) and cannon bone circumference (P = 0.02). However, head circumference /birth BW ratio (P = 0.04), heart girth /birth BW ratio (P = 0.01), body length /birth BW ratio (P = 0.05) and height /birth BW ratio (P = 0.01) was greater on LP calves. Body mass index was greater in HP calves (P = 0.04). No differences were found on BW of calves at weaning, adjusted 205d BW and ADG during lactation (P 〉 0.10). Glucose concentrations were greater on LP calves than HP calves from birth to weaning (81.0 ± 1.5 vs. 76.4 ± 1.2 mg/dl; P 〈 0.001) without any change in insulin concentrations during preweaning growth (LP = 1.61 ± 0.04 ng/ml; HP = 1.61 ± 0.04 ng/ml; P 〉 0.10). Insulin-like growth factor concentrations was less on LP calves at birth (P 〈 0.05) and similar to HP calves during postnatal growth (P 〉 0.10). These data demonstrate that low protein during late gestation in bovine dams may affect fetal growth with proportional increasing of head circumference and low body mass index. Level of protein compromised glucose regulation in early life and affected the IGF-I concentration of newborn calves.
publishDate 2018
dc.date.none.fl_str_mv 2018-06-07T14:42:58Z
2018-06-07T14:42:58Z
2018-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://www.sciencedirect.com/science/article/pii/S1871141318301057
http://hdl.handle.net/20.500.12123/2567
1871-1413
https://doi.org/10.1016/j.livsci.2018.04.009
url https://www.sciencedirect.com/science/article/pii/S1871141318301057
http://hdl.handle.net/20.500.12123/2567
https://doi.org/10.1016/j.livsci.2018.04.009
identifier_str_mv 1871-1413
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/restrictedAccess
eu_rights_str_mv restrictedAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv Livestock science 212 : 120-126. (June 2018)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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