Characterization of CD79acy + cells in placentas from ruminants

Autores
Canton, German Jose; Schock, Alex; Melo de Sousa, Noelita; Beckers, Jean-Francois; Chianini, Francesca
Año de publicación
2019
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Previous work carried out to characterise different immune cells in ruminant placentas found strong CD79αcynuclear labelling in cells histologically resembling trophoblast cells. In the attempt to characterize this cellpopulation, placentomes collected from cattle, sheep and water buffaloes were examined by im-munohistochemistry with single and double labelling using monoclonal antibodies (mAb) against B lymphocytesand trophoblast cells. Most CD79αcy+ cells co-expressed placental lactogen or cytokeratin and were CD21 andMHC class II negative strongly suggesting they do not have a B cell origin. However, a potential immunologicalrole of these cells cannot be ruled out and it is currently unknown if thefindings des
EEA Balcarce
Fil: Cantón, Germán José. Pentlands Science Park. Moredun Research Institute; Gran Bretaña. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina.
Fil: Schock, Alex. Pentlands Science Park. Animal and Plant Health Agency (APHA) Lasswade; Gran Bretaña
Fil: Melo de Sousa, Noelita. University of Liège. Faculty of Veterinary Medicine. Physiology of Reproduction; Bélgica
Fil: Beckers, Jeans Francois. University of Liège. Faculty of Veterinary Medicine. Physiology of Reproduction; Bélgica
Fil: Chianini, Francesca. Pentlands Science Park. Moredun Research Institute; Gran Bretaña
Fuente
Veterinary immunology and immunopathology 217 : 109942. (November 2019)
Materia
Respuesta Inmunológica
Placenta
Rumiante
Anticuerpos
Embriones Animales
Immune Response
Ruminants
Antibodies
Animal Embryos
Nivel de accesibilidad
acceso restringido
Condiciones de uso
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/6201
Acceder
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oai_identifier_str oai:localhost:20.500.12123/6201
network_acronym_str INTADig
repository_id_str l
network_name_str INTA Digital (INTA)
spelling Characterization of CD79acy + cells in placentas from ruminantsCanton, German JoseSchock, AlexMelo de Sousa, NoelitaBeckers, Jean-FrancoisChianini, FrancescaRespuesta InmunológicaPlacentaRumianteAnticuerposEmbriones AnimalesImmune ResponseRuminantsAntibodiesAnimal EmbryosPrevious work carried out to characterise different immune cells in ruminant placentas found strong CD79αcynuclear labelling in cells histologically resembling trophoblast cells. In the attempt to characterize this cellpopulation, placentomes collected from cattle, sheep and water buffaloes were examined by im-munohistochemistry with single and double labelling using monoclonal antibodies (mAb) against B lymphocytesand trophoblast cells. Most CD79αcy+ cells co-expressed placental lactogen or cytokeratin and were CD21 andMHC class II negative strongly suggesting they do not have a B cell origin. However, a potential immunologicalrole of these cells cannot be ruled out and it is currently unknown if thefindings desEEA BalcarceFil: Cantón, Germán José. Pentlands Science Park. Moredun Research Institute; Gran Bretaña. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina.Fil: Schock, Alex. Pentlands Science Park. Animal and Plant Health Agency (APHA) Lasswade; Gran BretañaFil: Melo de Sousa, Noelita. University of Liège. Faculty of Veterinary Medicine. Physiology of Reproduction; BélgicaFil: Beckers, Jeans Francois. University of Liège. Faculty of Veterinary Medicine. Physiology of Reproduction; BélgicaFil: Chianini, Francesca. Pentlands Science Park. Moredun Research Institute; Gran BretañaElsevier2019-10-24T18:42:15Z2019-10-24T18:42:15Z2019-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://www.sciencedirect.com/science/article/pii/S0165242719301849http://hdl.handle.net/20.500.12123/62010165-2427https://doi.org/10.1016/j.vetimm.2019.109942Veterinary immunology and immunopathology 217 : 109942. (November 2019)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repo/semantics/restrictedAccess2025-10-23T11:17:07Zoai:localhost:20.500.12123/6201instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-10-23 11:17:07.475INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Characterization of CD79acy + cells in placentas from ruminants
title Characterization of CD79acy + cells in placentas from ruminants
spellingShingle Characterization of CD79acy + cells in placentas from ruminants
Canton, German Jose
Respuesta Inmunológica
Placenta
Rumiante
Anticuerpos
Embriones Animales
Immune Response
Ruminants
Antibodies
Animal Embryos
title_short Characterization of CD79acy + cells in placentas from ruminants
title_full Characterization of CD79acy + cells in placentas from ruminants
title_fullStr Characterization of CD79acy + cells in placentas from ruminants
title_full_unstemmed Characterization of CD79acy + cells in placentas from ruminants
title_sort Characterization of CD79acy + cells in placentas from ruminants
dc.creator.none.fl_str_mv Canton, German Jose
Schock, Alex
Melo de Sousa, Noelita
Beckers, Jean-Francois
Chianini, Francesca
author Canton, German Jose
author_facet Canton, German Jose
Schock, Alex
Melo de Sousa, Noelita
Beckers, Jean-Francois
Chianini, Francesca
author_role author
author2 Schock, Alex
Melo de Sousa, Noelita
Beckers, Jean-Francois
Chianini, Francesca
author2_role author
author
author
author
dc.subject.none.fl_str_mv Respuesta Inmunológica
Placenta
Rumiante
Anticuerpos
Embriones Animales
Immune Response
Ruminants
Antibodies
Animal Embryos
topic Respuesta Inmunológica
Placenta
Rumiante
Anticuerpos
Embriones Animales
Immune Response
Ruminants
Antibodies
Animal Embryos
dc.description.none.fl_txt_mv Previous work carried out to characterise different immune cells in ruminant placentas found strong CD79αcynuclear labelling in cells histologically resembling trophoblast cells. In the attempt to characterize this cellpopulation, placentomes collected from cattle, sheep and water buffaloes were examined by im-munohistochemistry with single and double labelling using monoclonal antibodies (mAb) against B lymphocytesand trophoblast cells. Most CD79αcy+ cells co-expressed placental lactogen or cytokeratin and were CD21 andMHC class II negative strongly suggesting they do not have a B cell origin. However, a potential immunologicalrole of these cells cannot be ruled out and it is currently unknown if thefindings des
EEA Balcarce
Fil: Cantón, Germán José. Pentlands Science Park. Moredun Research Institute; Gran Bretaña. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina.
Fil: Schock, Alex. Pentlands Science Park. Animal and Plant Health Agency (APHA) Lasswade; Gran Bretaña
Fil: Melo de Sousa, Noelita. University of Liège. Faculty of Veterinary Medicine. Physiology of Reproduction; Bélgica
Fil: Beckers, Jeans Francois. University of Liège. Faculty of Veterinary Medicine. Physiology of Reproduction; Bélgica
Fil: Chianini, Francesca. Pentlands Science Park. Moredun Research Institute; Gran Bretaña
description Previous work carried out to characterise different immune cells in ruminant placentas found strong CD79αcynuclear labelling in cells histologically resembling trophoblast cells. In the attempt to characterize this cellpopulation, placentomes collected from cattle, sheep and water buffaloes were examined by im-munohistochemistry with single and double labelling using monoclonal antibodies (mAb) against B lymphocytesand trophoblast cells. Most CD79αcy+ cells co-expressed placental lactogen or cytokeratin and were CD21 andMHC class II negative strongly suggesting they do not have a B cell origin. However, a potential immunologicalrole of these cells cannot be ruled out and it is currently unknown if thefindings des
publishDate 2019
dc.date.none.fl_str_mv 2019-10-24T18:42:15Z
2019-10-24T18:42:15Z
2019-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://www.sciencedirect.com/science/article/pii/S0165242719301849
http://hdl.handle.net/20.500.12123/6201
0165-2427
https://doi.org/10.1016/j.vetimm.2019.109942
url https://www.sciencedirect.com/science/article/pii/S0165242719301849
http://hdl.handle.net/20.500.12123/6201
https://doi.org/10.1016/j.vetimm.2019.109942
identifier_str_mv 0165-2427
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/restrictedAccess
eu_rights_str_mv restrictedAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv Veterinary immunology and immunopathology 217 : 109942. (November 2019)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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score 12.982451

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