Prevalence and spatial distribution of bovine brucellosis in San Luis and La Pampa, Argentina

Autores
Aznar, Maria Natalia; Linares, Facundo José; Cosentino, Bernardo; Sago, Adrián Miguel; La Sala, Luciano Francisco; Leon, Eduardo; Duffy, Sergio; Perez, Andrés
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: Bovine brucellosis (BB) is a zoonotic disease caused by Brucella abortus. BB is endemic in Argentina, where vaccination with Brucella abortus strain 19 is compulsory for 3-to-8 month-old heifers. The objectives of this study were to quantify the prevalence of BB and to identify factors associated with its occurrence, along with the spatial distribution of the disease, in the provinces of La Pampa and San Luis. A two-stage random sampling design was used to sample 8,965 cows (3,513 in La Pampa and 5,452 in San Luis) from 451 farms (187 in La Pampa and 264 in San Luis). Results: Cow and herd prevalence were 1.8 % (95 % CI: 1.3–2.2; n = 157) and 19.7 % (95 % CI: 17.0–22.4; n = 89), respectively. Both cow-level and herd-level prevalence in La Pampa (2.4 and 26.0 %, respectively) were significantly higher than in San Luis (1.4 and 15.5 %, respectively). There were not differences between the proportions of reactive cattle compared to that obtained in a survey conducted in 2005. However, herd prevalence in La Pampa was significantly (P < 0.05) higher compared to that study. Disease was found to be spatially clustered in west La Pampa. The lower the bovine density and the calf/cow ratio, the higher odds of belonging to the cluster. Conclusions: The increase of farm prevalence in the last five years suggests that the disease is spreading and that control measures should be applied in the region. The cluster of infected farms was located in the west region of La Pampa. There, farms have lower animal densities and smaller cow/calf indices compared to the rest of the province. Although western La Pampa has more infected herds, within-farm prevalence was not higher, which suggests that the control program has been relatively successful in controlling the disease at the farm level, and/or that low animal density inherently results in low disease prevalence. Our results provide baseline information on the epidemiology of BB and its potential pattern of transmission in Argentina, which will ultimately help to improve BB control programs in the country.
Instituto de Patobiología
Fil: Aznar, Maria Natalia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología. Area de Patología, Epidemiología y Medicina Preventiva; Argentina. University of Liege. Faculty of Veterinary Medicine. Department of Infectious and Parasitic Diseases. Research Unit of Epidemiology and Risk Analysis Applied to Veterinary Sciences; Belgica
Fil: Linares, Facundo José. Servicio Nacional de Sanidad y Calidad Agroalimentaria. Dirección Nacional de Sanidad Animal. Dirección de Epidemiología y Análisis de Riesgo; Argentina
Fil: Cosentino, Bernardo. Servicio Nacional de Sanidad y Calidad Agroalimentaria. Dirección Nacional de Sanidad Animal. Dirección de Epidemiología y Análisis de Riesgo; Argentina
Fil: Sago, Adrián Miguel. Servicio Nacional de Sanidad y Calidad Agroalimentaria. Centro Regional La Pampa-San Luis; Argentina
Fil: La Sala, Luciano Francisco. Universidad Nacional del Sur. Bioquímica y Farmacia. Cátedra de Parasitología Cínica. Departamento de Biología; Argentina
Fil: Leon, Eduardo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología. Area de Patología, Epidemiología y Medicina Preventiva; Argentina
Fil: Duffy, Sergio. Universidad Nacional de Rosario. Facultad de Ciencias Veterinarias. Centro de Estudios Cuantitativos en Sanidad Animal; Argentina
Fil: Perez, Andrés. University of Minnesota. College of Veterinary Medicine. Department of Veterinary Population Medicine; Estados Unidos
Fuente
BMC veterinary research 11 : 209. (2015)
Materia
Morbosidad
Distribución Espacial
Brucella Abortus
Morbidity
Spatial Distribution
Prevalence
Prevalencia de una Enfermedad
Bovine Brucellosis
Brucelosis Bovina
San Luis
La Pampa
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
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spelling Prevalence and spatial distribution of bovine brucellosis in San Luis and La Pampa, ArgentinaAznar, Maria NataliaLinares, Facundo JoséCosentino, BernardoSago, Adrián MiguelLa Sala, Luciano FranciscoLeon, EduardoDuffy, SergioPerez, AndrésMorbosidadDistribución EspacialBrucella AbortusMorbiditySpatial DistributionPrevalencePrevalencia de una EnfermedadBovine BrucellosisBrucelosis BovinaSan LuisLa PampaBackground: Bovine brucellosis (BB) is a zoonotic disease caused by Brucella abortus. BB is endemic in Argentina, where vaccination with Brucella abortus strain 19 is compulsory for 3-to-8 month-old heifers. The objectives of this study were to quantify the prevalence of BB and to identify factors associated with its occurrence, along with the spatial distribution of the disease, in the provinces of La Pampa and San Luis. A two-stage random sampling design was used to sample 8,965 cows (3,513 in La Pampa and 5,452 in San Luis) from 451 farms (187 in La Pampa and 264 in San Luis). Results: Cow and herd prevalence were 1.8 % (95 % CI: 1.3–2.2; n = 157) and 19.7 % (95 % CI: 17.0–22.4; n = 89), respectively. Both cow-level and herd-level prevalence in La Pampa (2.4 and 26.0 %, respectively) were significantly higher than in San Luis (1.4 and 15.5 %, respectively). There were not differences between the proportions of reactive cattle compared to that obtained in a survey conducted in 2005. However, herd prevalence in La Pampa was significantly (P < 0.05) higher compared to that study. Disease was found to be spatially clustered in west La Pampa. The lower the bovine density and the calf/cow ratio, the higher odds of belonging to the cluster. Conclusions: The increase of farm prevalence in the last five years suggests that the disease is spreading and that control measures should be applied in the region. The cluster of infected farms was located in the west region of La Pampa. There, farms have lower animal densities and smaller cow/calf indices compared to the rest of the province. Although western La Pampa has more infected herds, within-farm prevalence was not higher, which suggests that the control program has been relatively successful in controlling the disease at the farm level, and/or that low animal density inherently results in low disease prevalence. Our results provide baseline information on the epidemiology of BB and its potential pattern of transmission in Argentina, which will ultimately help to improve BB control programs in the country.Instituto de PatobiologíaFil: Aznar, Maria Natalia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología. Area de Patología, Epidemiología y Medicina Preventiva; Argentina. University of Liege. Faculty of Veterinary Medicine. Department of Infectious and Parasitic Diseases. Research Unit of Epidemiology and Risk Analysis Applied to Veterinary Sciences; BelgicaFil: Linares, Facundo José. Servicio Nacional de Sanidad y Calidad Agroalimentaria. Dirección Nacional de Sanidad Animal. Dirección de Epidemiología y Análisis de Riesgo; ArgentinaFil: Cosentino, Bernardo. Servicio Nacional de Sanidad y Calidad Agroalimentaria. Dirección Nacional de Sanidad Animal. Dirección de Epidemiología y Análisis de Riesgo; ArgentinaFil: Sago, Adrián Miguel. Servicio Nacional de Sanidad y Calidad Agroalimentaria. Centro Regional La Pampa-San Luis; ArgentinaFil: La Sala, Luciano Francisco. Universidad Nacional del Sur. Bioquímica y Farmacia. Cátedra de Parasitología Cínica. Departamento de Biología; ArgentinaFil: Leon, Eduardo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología. Area de Patología, Epidemiología y Medicina Preventiva; ArgentinaFil: Duffy, Sergio. Universidad Nacional de Rosario. Facultad de Ciencias Veterinarias. Centro de Estudios Cuantitativos en Sanidad Animal; ArgentinaFil: Perez, Andrés. University of Minnesota. College of Veterinary Medicine. Department of Veterinary Population Medicine; Estados UnidosBioMed Central2019-02-20T15:14:28Z2019-02-20T15:14:28Z2015info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/4475https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-015-0535-11746-6148https://doi.org/10.1186/s12917-015-0535-1BMC veterinary research 11 : 209. (2015)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología AgropecuariaengSan Luis (province)Argentina (nation)info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)2025-09-29T13:44:34Zoai:localhost:20.500.12123/4475instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-09-29 13:44:35.077INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Prevalence and spatial distribution of bovine brucellosis in San Luis and La Pampa, Argentina
title Prevalence and spatial distribution of bovine brucellosis in San Luis and La Pampa, Argentina
spellingShingle Prevalence and spatial distribution of bovine brucellosis in San Luis and La Pampa, Argentina
Aznar, Maria Natalia
Morbosidad
Distribución Espacial
Brucella Abortus
Morbidity
Spatial Distribution
Prevalence
Prevalencia de una Enfermedad
Bovine Brucellosis
Brucelosis Bovina
San Luis
La Pampa
title_short Prevalence and spatial distribution of bovine brucellosis in San Luis and La Pampa, Argentina
title_full Prevalence and spatial distribution of bovine brucellosis in San Luis and La Pampa, Argentina
title_fullStr Prevalence and spatial distribution of bovine brucellosis in San Luis and La Pampa, Argentina
title_full_unstemmed Prevalence and spatial distribution of bovine brucellosis in San Luis and La Pampa, Argentina
title_sort Prevalence and spatial distribution of bovine brucellosis in San Luis and La Pampa, Argentina
dc.creator.none.fl_str_mv Aznar, Maria Natalia
Linares, Facundo José
Cosentino, Bernardo
Sago, Adrián Miguel
La Sala, Luciano Francisco
Leon, Eduardo
Duffy, Sergio
Perez, Andrés
author Aznar, Maria Natalia
author_facet Aznar, Maria Natalia
Linares, Facundo José
Cosentino, Bernardo
Sago, Adrián Miguel
La Sala, Luciano Francisco
Leon, Eduardo
Duffy, Sergio
Perez, Andrés
author_role author
author2 Linares, Facundo José
Cosentino, Bernardo
Sago, Adrián Miguel
La Sala, Luciano Francisco
Leon, Eduardo
Duffy, Sergio
Perez, Andrés
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Morbosidad
Distribución Espacial
Brucella Abortus
Morbidity
Spatial Distribution
Prevalence
Prevalencia de una Enfermedad
Bovine Brucellosis
Brucelosis Bovina
San Luis
La Pampa
topic Morbosidad
Distribución Espacial
Brucella Abortus
Morbidity
Spatial Distribution
Prevalence
Prevalencia de una Enfermedad
Bovine Brucellosis
Brucelosis Bovina
San Luis
La Pampa
dc.description.none.fl_txt_mv Background: Bovine brucellosis (BB) is a zoonotic disease caused by Brucella abortus. BB is endemic in Argentina, where vaccination with Brucella abortus strain 19 is compulsory for 3-to-8 month-old heifers. The objectives of this study were to quantify the prevalence of BB and to identify factors associated with its occurrence, along with the spatial distribution of the disease, in the provinces of La Pampa and San Luis. A two-stage random sampling design was used to sample 8,965 cows (3,513 in La Pampa and 5,452 in San Luis) from 451 farms (187 in La Pampa and 264 in San Luis). Results: Cow and herd prevalence were 1.8 % (95 % CI: 1.3–2.2; n = 157) and 19.7 % (95 % CI: 17.0–22.4; n = 89), respectively. Both cow-level and herd-level prevalence in La Pampa (2.4 and 26.0 %, respectively) were significantly higher than in San Luis (1.4 and 15.5 %, respectively). There were not differences between the proportions of reactive cattle compared to that obtained in a survey conducted in 2005. However, herd prevalence in La Pampa was significantly (P < 0.05) higher compared to that study. Disease was found to be spatially clustered in west La Pampa. The lower the bovine density and the calf/cow ratio, the higher odds of belonging to the cluster. Conclusions: The increase of farm prevalence in the last five years suggests that the disease is spreading and that control measures should be applied in the region. The cluster of infected farms was located in the west region of La Pampa. There, farms have lower animal densities and smaller cow/calf indices compared to the rest of the province. Although western La Pampa has more infected herds, within-farm prevalence was not higher, which suggests that the control program has been relatively successful in controlling the disease at the farm level, and/or that low animal density inherently results in low disease prevalence. Our results provide baseline information on the epidemiology of BB and its potential pattern of transmission in Argentina, which will ultimately help to improve BB control programs in the country.
Instituto de Patobiología
Fil: Aznar, Maria Natalia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología. Area de Patología, Epidemiología y Medicina Preventiva; Argentina. University of Liege. Faculty of Veterinary Medicine. Department of Infectious and Parasitic Diseases. Research Unit of Epidemiology and Risk Analysis Applied to Veterinary Sciences; Belgica
Fil: Linares, Facundo José. Servicio Nacional de Sanidad y Calidad Agroalimentaria. Dirección Nacional de Sanidad Animal. Dirección de Epidemiología y Análisis de Riesgo; Argentina
Fil: Cosentino, Bernardo. Servicio Nacional de Sanidad y Calidad Agroalimentaria. Dirección Nacional de Sanidad Animal. Dirección de Epidemiología y Análisis de Riesgo; Argentina
Fil: Sago, Adrián Miguel. Servicio Nacional de Sanidad y Calidad Agroalimentaria. Centro Regional La Pampa-San Luis; Argentina
Fil: La Sala, Luciano Francisco. Universidad Nacional del Sur. Bioquímica y Farmacia. Cátedra de Parasitología Cínica. Departamento de Biología; Argentina
Fil: Leon, Eduardo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología. Area de Patología, Epidemiología y Medicina Preventiva; Argentina
Fil: Duffy, Sergio. Universidad Nacional de Rosario. Facultad de Ciencias Veterinarias. Centro de Estudios Cuantitativos en Sanidad Animal; Argentina
Fil: Perez, Andrés. University of Minnesota. College of Veterinary Medicine. Department of Veterinary Population Medicine; Estados Unidos
description Background: Bovine brucellosis (BB) is a zoonotic disease caused by Brucella abortus. BB is endemic in Argentina, where vaccination with Brucella abortus strain 19 is compulsory for 3-to-8 month-old heifers. The objectives of this study were to quantify the prevalence of BB and to identify factors associated with its occurrence, along with the spatial distribution of the disease, in the provinces of La Pampa and San Luis. A two-stage random sampling design was used to sample 8,965 cows (3,513 in La Pampa and 5,452 in San Luis) from 451 farms (187 in La Pampa and 264 in San Luis). Results: Cow and herd prevalence were 1.8 % (95 % CI: 1.3–2.2; n = 157) and 19.7 % (95 % CI: 17.0–22.4; n = 89), respectively. Both cow-level and herd-level prevalence in La Pampa (2.4 and 26.0 %, respectively) were significantly higher than in San Luis (1.4 and 15.5 %, respectively). There were not differences between the proportions of reactive cattle compared to that obtained in a survey conducted in 2005. However, herd prevalence in La Pampa was significantly (P < 0.05) higher compared to that study. Disease was found to be spatially clustered in west La Pampa. The lower the bovine density and the calf/cow ratio, the higher odds of belonging to the cluster. Conclusions: The increase of farm prevalence in the last five years suggests that the disease is spreading and that control measures should be applied in the region. The cluster of infected farms was located in the west region of La Pampa. There, farms have lower animal densities and smaller cow/calf indices compared to the rest of the province. Although western La Pampa has more infected herds, within-farm prevalence was not higher, which suggests that the control program has been relatively successful in controlling the disease at the farm level, and/or that low animal density inherently results in low disease prevalence. Our results provide baseline information on the epidemiology of BB and its potential pattern of transmission in Argentina, which will ultimately help to improve BB control programs in the country.
publishDate 2015
dc.date.none.fl_str_mv 2015
2019-02-20T15:14:28Z
2019-02-20T15:14:28Z
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/4475
https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-015-0535-1
1746-6148
https://doi.org/10.1186/s12917-015-0535-1
url http://hdl.handle.net/20.500.12123/4475
https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-015-0535-1
https://doi.org/10.1186/s12917-015-0535-1
identifier_str_mv 1746-6148
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
dc.coverage.none.fl_str_mv San Luis (province)
Argentina (nation)
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv BMC veterinary research 11 : 209. (2015)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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