Circadian oscillation of gibberellin signaling in Arabidopsis

Autores
Arana, María Veronica; Marín de la Rosa, Nora; Maloof, Julin N.; Blazquez, Miguel Angel; Alabadí, David
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Circadian clocks are endogenous timekeeping mechanisms that allow organisms to anticipate rhythmic, daily environmental changes. Temporal coordination of transcription results in a set of gene expression patterns with peak levels occurring at precise times of the day. An intriguing question is how a single clock can generate different oscillatory rhythms, and it has been proposed that hormone signaling might act in plants as a relay mechanism to modulate the amplitude and the phase of output rhythms. Here we show that the circadian clock gates gibberellin (GA) signaling through transcriptional regulation of the GA receptors, resulting in higher stability of DELLA proteins during daytime and higher GA sensitivity at night. Oscillation of GA signaling appears to be particularly critical for rhythmic growth, given that constitutive expression of the GA receptor expands the daily growth period in seedlings, and complete loss of DELLA function causes continuous, arrhythmic hypocotyl growth. Moreover, transcriptomic analysis of a pentuple della KO mutant indicates that the GA pathway mediates the rhythmic expression of many clock-regulated genes related to biotic and abiotic stress responses and cell wall modification. Thus, gating of GA sensitivity by the circadian clock represents an additional layer of regulation that might provide extra robustness to the diurnal growth rhythm and constitute a regulatory module that coordinates the circadian clock with additional endogenous and environmental signals.
Fil: Arana, María Veronica. Intituto Nacional de Tecnologia Agropecuaria (INTA). Estacion Experimental Agropecuaria Bariloche. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Marín de la Rosa, Nora. Universitat Politecnica de Valencia. Instituto de Biología Molecular y Celular de Plantas; España
Fil: Maloof, Julin N. University of California. Department of Plant Biology; Estados Unidos
Fil: Blazquez, Miguel Angel. Universidad Politécnica de Valencia. Consejo Superior de Investigaciones Científicas. Institute of Molecular and Plant Cellular Biology; España
Fil: Alabadí, David. Universitat Politecnica de Valencia. Instituto de Biología Molecular y Celular de Plantas; España
Fuente
PNAS 108 (22) : 9292-9297 (Mayo 2011)
Materia
Plasticidad Fenotípica
Fotoperiodismo
Arabidopsis
Phenotypic Plasticity
Photoperiodicity
Reloj Circadiano
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/7683
Acceder
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oai_identifier_str oai:localhost:20.500.12123/7683
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spelling Circadian oscillation of gibberellin signaling in ArabidopsisArana, María VeronicaMarín de la Rosa, NoraMaloof, Julin N.Blazquez, Miguel AngelAlabadí, DavidPlasticidad FenotípicaFotoperiodismoArabidopsisPhenotypic PlasticityPhotoperiodicityReloj CircadianoCircadian clocks are endogenous timekeeping mechanisms that allow organisms to anticipate rhythmic, daily environmental changes. Temporal coordination of transcription results in a set of gene expression patterns with peak levels occurring at precise times of the day. An intriguing question is how a single clock can generate different oscillatory rhythms, and it has been proposed that hormone signaling might act in plants as a relay mechanism to modulate the amplitude and the phase of output rhythms. Here we show that the circadian clock gates gibberellin (GA) signaling through transcriptional regulation of the GA receptors, resulting in higher stability of DELLA proteins during daytime and higher GA sensitivity at night. Oscillation of GA signaling appears to be particularly critical for rhythmic growth, given that constitutive expression of the GA receptor expands the daily growth period in seedlings, and complete loss of DELLA function causes continuous, arrhythmic hypocotyl growth. Moreover, transcriptomic analysis of a pentuple della KO mutant indicates that the GA pathway mediates the rhythmic expression of many clock-regulated genes related to biotic and abiotic stress responses and cell wall modification. Thus, gating of GA sensitivity by the circadian clock represents an additional layer of regulation that might provide extra robustness to the diurnal growth rhythm and constitute a regulatory module that coordinates the circadian clock with additional endogenous and environmental signals.Fil: Arana, María Veronica. Intituto Nacional de Tecnologia Agropecuaria (INTA). Estacion Experimental Agropecuaria Bariloche. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Marín de la Rosa, Nora. Universitat Politecnica de Valencia. Instituto de Biología Molecular y Celular de Plantas; EspañaFil: Maloof, Julin N. University of California. Department of Plant Biology; Estados UnidosFil: Blazquez, Miguel Angel. Universidad Politécnica de Valencia. Consejo Superior de Investigaciones Científicas. Institute of Molecular and Plant Cellular Biology; EspañaFil: Alabadí, David. Universitat Politecnica de Valencia. Instituto de Biología Molecular y Celular de Plantas; EspañaNational Academy of Sciences2020-08-06T19:21:42Z2020-08-06T19:21:42Z2011-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/7683https://www.pnas.org/content/108/22/92921091-64900027-8424https://doi.org/10.1073/pnas.1101050108PNAS 108 (22) : 9292-9297 (Mayo 2011)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)2025-09-29T13:44:59Zoai:localhost:20.500.12123/7683instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-09-29 13:45:00.152INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Circadian oscillation of gibberellin signaling in Arabidopsis
title Circadian oscillation of gibberellin signaling in Arabidopsis
spellingShingle Circadian oscillation of gibberellin signaling in Arabidopsis
Arana, María Veronica
Plasticidad Fenotípica
Fotoperiodismo
Arabidopsis
Phenotypic Plasticity
Photoperiodicity
Reloj Circadiano
title_short Circadian oscillation of gibberellin signaling in Arabidopsis
title_full Circadian oscillation of gibberellin signaling in Arabidopsis
title_fullStr Circadian oscillation of gibberellin signaling in Arabidopsis
title_full_unstemmed Circadian oscillation of gibberellin signaling in Arabidopsis
title_sort Circadian oscillation of gibberellin signaling in Arabidopsis
dc.creator.none.fl_str_mv Arana, María Veronica
Marín de la Rosa, Nora
Maloof, Julin N.
Blazquez, Miguel Angel
Alabadí, David
author Arana, María Veronica
author_facet Arana, María Veronica
Marín de la Rosa, Nora
Maloof, Julin N.
Blazquez, Miguel Angel
Alabadí, David
author_role author
author2 Marín de la Rosa, Nora
Maloof, Julin N.
Blazquez, Miguel Angel
Alabadí, David
author2_role author
author
author
author
dc.subject.none.fl_str_mv Plasticidad Fenotípica
Fotoperiodismo
Arabidopsis
Phenotypic Plasticity
Photoperiodicity
Reloj Circadiano
topic Plasticidad Fenotípica
Fotoperiodismo
Arabidopsis
Phenotypic Plasticity
Photoperiodicity
Reloj Circadiano
dc.description.none.fl_txt_mv Circadian clocks are endogenous timekeeping mechanisms that allow organisms to anticipate rhythmic, daily environmental changes. Temporal coordination of transcription results in a set of gene expression patterns with peak levels occurring at precise times of the day. An intriguing question is how a single clock can generate different oscillatory rhythms, and it has been proposed that hormone signaling might act in plants as a relay mechanism to modulate the amplitude and the phase of output rhythms. Here we show that the circadian clock gates gibberellin (GA) signaling through transcriptional regulation of the GA receptors, resulting in higher stability of DELLA proteins during daytime and higher GA sensitivity at night. Oscillation of GA signaling appears to be particularly critical for rhythmic growth, given that constitutive expression of the GA receptor expands the daily growth period in seedlings, and complete loss of DELLA function causes continuous, arrhythmic hypocotyl growth. Moreover, transcriptomic analysis of a pentuple della KO mutant indicates that the GA pathway mediates the rhythmic expression of many clock-regulated genes related to biotic and abiotic stress responses and cell wall modification. Thus, gating of GA sensitivity by the circadian clock represents an additional layer of regulation that might provide extra robustness to the diurnal growth rhythm and constitute a regulatory module that coordinates the circadian clock with additional endogenous and environmental signals.
Fil: Arana, María Veronica. Intituto Nacional de Tecnologia Agropecuaria (INTA). Estacion Experimental Agropecuaria Bariloche. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Marín de la Rosa, Nora. Universitat Politecnica de Valencia. Instituto de Biología Molecular y Celular de Plantas; España
Fil: Maloof, Julin N. University of California. Department of Plant Biology; Estados Unidos
Fil: Blazquez, Miguel Angel. Universidad Politécnica de Valencia. Consejo Superior de Investigaciones Científicas. Institute of Molecular and Plant Cellular Biology; España
Fil: Alabadí, David. Universitat Politecnica de Valencia. Instituto de Biología Molecular y Celular de Plantas; España
description Circadian clocks are endogenous timekeeping mechanisms that allow organisms to anticipate rhythmic, daily environmental changes. Temporal coordination of transcription results in a set of gene expression patterns with peak levels occurring at precise times of the day. An intriguing question is how a single clock can generate different oscillatory rhythms, and it has been proposed that hormone signaling might act in plants as a relay mechanism to modulate the amplitude and the phase of output rhythms. Here we show that the circadian clock gates gibberellin (GA) signaling through transcriptional regulation of the GA receptors, resulting in higher stability of DELLA proteins during daytime and higher GA sensitivity at night. Oscillation of GA signaling appears to be particularly critical for rhythmic growth, given that constitutive expression of the GA receptor expands the daily growth period in seedlings, and complete loss of DELLA function causes continuous, arrhythmic hypocotyl growth. Moreover, transcriptomic analysis of a pentuple della KO mutant indicates that the GA pathway mediates the rhythmic expression of many clock-regulated genes related to biotic and abiotic stress responses and cell wall modification. Thus, gating of GA sensitivity by the circadian clock represents an additional layer of regulation that might provide extra robustness to the diurnal growth rhythm and constitute a regulatory module that coordinates the circadian clock with additional endogenous and environmental signals.
publishDate 2011
dc.date.none.fl_str_mv 2011-05
2020-08-06T19:21:42Z
2020-08-06T19:21:42Z
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/7683
https://www.pnas.org/content/108/22/9292
1091-6490
0027-8424
https://doi.org/10.1073/pnas.1101050108
url http://hdl.handle.net/20.500.12123/7683
https://www.pnas.org/content/108/22/9292
https://doi.org/10.1073/pnas.1101050108
identifier_str_mv 1091-6490
0027-8424
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv National Academy of Sciences
publisher.none.fl_str_mv National Academy of Sciences
dc.source.none.fl_str_mv PNAS 108 (22) : 9292-9297 (Mayo 2011)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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score 12.559606

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