The efficacy of a trivalent inactivated salmonella vaccine combined with the live s. gallinarum 9R vaccine in young layers after experimental infections with s. enteritidis, s. typ...

Autores: Huberman, Yosef Daniel; Caballero García, Melanie; Rojas, Rober; Ascanio, Silvia.; Olmos, Leandro Hipolito; Malena, Rosana Claudia; Lomonaco, Jorgelina; Nievas, Paula Andrea; Chero, Paula; Lévano Gracía, Julio; Mendoza Espinoza, Alfredo
Año de publicación: 2022
Idioma: inglés
Tipo de recurso: artículo
Estado: versión publicada
Descripción: Worldwide, poultry infections by Salmonella are the cause of significant economic losses, not only due to reduced production (due to fowl typhoid disease), but also considering the efforts and control measures that must be constantly applied, especially due to zoonotic serovars. Poultry is a common reservoir of Salmonella and its transmission into the food chain is a risk for humans. The vaccination of layers plays an important role in the overall efforts to prevent Salmonella infections. An inactivated trivalent vaccine was prepared with S. Enteritidis, S. Typhimurium, and S. Infantis strains. Infection trials were performed to evaluate the efficacy of three vaccination schedules using inactivated and live S. Gallinarum 9R vaccines. For this purpose, at week 5 of life, one subcutaneous dose of live S. Gallinarum 9R vaccine (1–5 × 107 CFU) was given to Groups 1 and 2. At weeks 8 and 11 of life, chickens were also vaccinated with one (Group 1) or two (Groups 2 and 3) intramuscular doses of the inactivated oil-adjuvant trivalent vaccine (1 × 108 CFU/dose of each antigen). Group 4 consisted of chickens that remained unvaccinated (control). At week 14 of life, the efficacy of the vaccination plans was evaluated in three separate inoculation trials with S. Enteritidis, S. Typhimurium, or S. Infantis. After vaccination with the inactivated vaccine, homologous antibody production was observed, and after challenge, a significant reduction in the faecal shedding, invasion, and colonization of S. Typhimurium and S. Infantis was achieved by all vaccination schedules, while the vaccination with at least one dose of the live S. Gallinarum 9R vaccine was necessary to obtain such a significant protection against S. Enteritidis infection.
EEA Balcarce
Fil: Huberman, Yosef Daniel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina.
Fil: Caballero Garcia, Melanie. Quimtia. Research and Development; Perú.
Fil: Rojas, Rober. Quimtia. Research and Development; Perú.
Fil: Ascanio, Silvia. Quimtia. Research and Development; Perú.
Fil: Olmos, Leandro Hipólito. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina.
Fil: Malena, Rosana Claudia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina.
Fil: Lomónaco, Jorgelina. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina.
Fil: Nievas, Paula Andrea. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina.
Fil: Chero, Paula. Quimtia. Research and Development; Perú.
Fil: Lévano Gracía, Julio. Quimtia. Research and Development; Perú.
Fil: Mendoza Espinoza, Alfredo. Quimtia. Research and Development; Perú.
Fuente: Vaccines 10 (7) : 1113 (July 2022)
Materia: Pollo
Vacuna Inactivada
Salmonella
Salmonella Enteritidis
Salmonella Typhimurium
Chickens
Inactivated Vaccines
Salmonella Infantis
Nivel de accesibilidad: acceso abierto
Condiciones de uso: http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
Institución: Instituto Nacional de Tecnología Agropecuaria
OAI Identificador: oai:localhost:20.500.12123/12505

Acceder

id	INTADig_285865410527a201dcdc711a5dad4c20
oai_identifier_str	oai:localhost:20.500.12123/12505
network_acronym_str	INTADig
repository_id_str	l
network_name_str	INTA Digital (INTA)
spelling	The efficacy of a trivalent inactivated salmonella vaccine combined with the live s. gallinarum 9R vaccine in young layers after experimental infections with s. enteritidis, s. typhimurium, and s. infantisHuberman, Yosef DanielCaballero García, MelanieRojas, RoberAscanio, Silvia.Olmos, Leandro HipolitoMalena, Rosana ClaudiaLomonaco, JorgelinaNievas, Paula AndreaChero, PaulaLévano Gracía, JulioMendoza Espinoza, AlfredoPolloVacuna InactivadaSalmonellaSalmonella EnteritidisSalmonella TyphimuriumChickensInactivated VaccinesSalmonella InfantisWorldwide, poultry infections by Salmonella are the cause of significant economic losses, not only due to reduced production (due to fowl typhoid disease), but also considering the efforts and control measures that must be constantly applied, especially due to zoonotic serovars. Poultry is a common reservoir of Salmonella and its transmission into the food chain is a risk for humans. The vaccination of layers plays an important role in the overall efforts to prevent Salmonella infections. An inactivated trivalent vaccine was prepared with S. Enteritidis, S. Typhimurium, and S. Infantis strains. Infection trials were performed to evaluate the efficacy of three vaccination schedules using inactivated and live S. Gallinarum 9R vaccines. For this purpose, at week 5 of life, one subcutaneous dose of live S. Gallinarum 9R vaccine (1–5 × 107 CFU) was given to Groups 1 and 2. At weeks 8 and 11 of life, chickens were also vaccinated with one (Group 1) or two (Groups 2 and 3) intramuscular doses of the inactivated oil-adjuvant trivalent vaccine (1 × 108 CFU/dose of each antigen). Group 4 consisted of chickens that remained unvaccinated (control). At week 14 of life, the efficacy of the vaccination plans was evaluated in three separate inoculation trials with S. Enteritidis, S. Typhimurium, or S. Infantis. After vaccination with the inactivated vaccine, homologous antibody production was observed, and after challenge, a significant reduction in the faecal shedding, invasion, and colonization of S. Typhimurium and S. Infantis was achieved by all vaccination schedules, while the vaccination with at least one dose of the live S. Gallinarum 9R vaccine was necessary to obtain such a significant protection against S. Enteritidis infection.EEA BalcarceFil: Huberman, Yosef Daniel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina.Fil: Caballero Garcia, Melanie. Quimtia. Research and Development; Perú.Fil: Rojas, Rober. Quimtia. Research and Development; Perú.Fil: Ascanio, Silvia. Quimtia. Research and Development; Perú.Fil: Olmos, Leandro Hipólito. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina.Fil: Malena, Rosana Claudia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina.Fil: Lomónaco, Jorgelina. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina.Fil: Nievas, Paula Andrea. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina.Fil: Chero, Paula. Quimtia. Research and Development; Perú.Fil: Lévano Gracía, Julio. Quimtia. Research and Development; Perú.Fil: Mendoza Espinoza, Alfredo. Quimtia. Research and Development; Perú.MDPI2022-08-05T11:13:38Z2022-08-05T11:13:38Z2022-07-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/12505https://www.mdpi.com/2076-393X/10/7/11132076-393Xhttps://doi.org/10.3390/vaccines10071113Vaccines 10 (7) : 1113 (July 2022)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)2025-09-29T13:45:39Zoai:localhost:20.500.12123/12505instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-09-29 13:45:39.556INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv	The efficacy of a trivalent inactivated salmonella vaccine combined with the live s. gallinarum 9R vaccine in young layers after experimental infections with s. enteritidis, s. typhimurium, and s. infantis
title	The efficacy of a trivalent inactivated salmonella vaccine combined with the live s. gallinarum 9R vaccine in young layers after experimental infections with s. enteritidis, s. typhimurium, and s. infantis
spellingShingle	The efficacy of a trivalent inactivated salmonella vaccine combined with the live s. gallinarum 9R vaccine in young layers after experimental infections with s. enteritidis, s. typhimurium, and s. infantis Huberman, Yosef Daniel Pollo Vacuna Inactivada Salmonella Salmonella Enteritidis Salmonella Typhimurium Chickens Inactivated Vaccines Salmonella Infantis
title_short	The efficacy of a trivalent inactivated salmonella vaccine combined with the live s. gallinarum 9R vaccine in young layers after experimental infections with s. enteritidis, s. typhimurium, and s. infantis
title_full	The efficacy of a trivalent inactivated salmonella vaccine combined with the live s. gallinarum 9R vaccine in young layers after experimental infections with s. enteritidis, s. typhimurium, and s. infantis
title_fullStr	The efficacy of a trivalent inactivated salmonella vaccine combined with the live s. gallinarum 9R vaccine in young layers after experimental infections with s. enteritidis, s. typhimurium, and s. infantis
title_full_unstemmed	The efficacy of a trivalent inactivated salmonella vaccine combined with the live s. gallinarum 9R vaccine in young layers after experimental infections with s. enteritidis, s. typhimurium, and s. infantis
title_sort	The efficacy of a trivalent inactivated salmonella vaccine combined with the live s. gallinarum 9R vaccine in young layers after experimental infections with s. enteritidis, s. typhimurium, and s. infantis
dc.creator.none.fl_str_mv	Huberman, Yosef Daniel Caballero García, Melanie Rojas, Rober Ascanio, Silvia. Olmos, Leandro Hipolito Malena, Rosana Claudia Lomonaco, Jorgelina Nievas, Paula Andrea Chero, Paula Lévano Gracía, Julio Mendoza Espinoza, Alfredo
author	Huberman, Yosef Daniel
author_facet	Huberman, Yosef Daniel Caballero García, Melanie Rojas, Rober Ascanio, Silvia. Olmos, Leandro Hipolito Malena, Rosana Claudia Lomonaco, Jorgelina Nievas, Paula Andrea Chero, Paula Lévano Gracía, Julio Mendoza Espinoza, Alfredo
author_role	author
author2	Caballero García, Melanie Rojas, Rober Ascanio, Silvia. Olmos, Leandro Hipolito Malena, Rosana Claudia Lomonaco, Jorgelina Nievas, Paula Andrea Chero, Paula Lévano Gracía, Julio Mendoza Espinoza, Alfredo
author2_role	author author author author author author author author author author
dc.subject.none.fl_str_mv	Pollo Vacuna Inactivada Salmonella Salmonella Enteritidis Salmonella Typhimurium Chickens Inactivated Vaccines Salmonella Infantis
topic	Pollo Vacuna Inactivada Salmonella Salmonella Enteritidis Salmonella Typhimurium Chickens Inactivated Vaccines Salmonella Infantis
dc.description.none.fl_txt_mv	Worldwide, poultry infections by Salmonella are the cause of significant economic losses, not only due to reduced production (due to fowl typhoid disease), but also considering the efforts and control measures that must be constantly applied, especially due to zoonotic serovars. Poultry is a common reservoir of Salmonella and its transmission into the food chain is a risk for humans. The vaccination of layers plays an important role in the overall efforts to prevent Salmonella infections. An inactivated trivalent vaccine was prepared with S. Enteritidis, S. Typhimurium, and S. Infantis strains. Infection trials were performed to evaluate the efficacy of three vaccination schedules using inactivated and live S. Gallinarum 9R vaccines. For this purpose, at week 5 of life, one subcutaneous dose of live S. Gallinarum 9R vaccine (1–5 × 107 CFU) was given to Groups 1 and 2. At weeks 8 and 11 of life, chickens were also vaccinated with one (Group 1) or two (Groups 2 and 3) intramuscular doses of the inactivated oil-adjuvant trivalent vaccine (1 × 108 CFU/dose of each antigen). Group 4 consisted of chickens that remained unvaccinated (control). At week 14 of life, the efficacy of the vaccination plans was evaluated in three separate inoculation trials with S. Enteritidis, S. Typhimurium, or S. Infantis. After vaccination with the inactivated vaccine, homologous antibody production was observed, and after challenge, a significant reduction in the faecal shedding, invasion, and colonization of S. Typhimurium and S. Infantis was achieved by all vaccination schedules, while the vaccination with at least one dose of the live S. Gallinarum 9R vaccine was necessary to obtain such a significant protection against S. Enteritidis infection. EEA Balcarce Fil: Huberman, Yosef Daniel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Fil: Caballero Garcia, Melanie. Quimtia. Research and Development; Perú. Fil: Rojas, Rober. Quimtia. Research and Development; Perú. Fil: Ascanio, Silvia. Quimtia. Research and Development; Perú. Fil: Olmos, Leandro Hipólito. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Fil: Malena, Rosana Claudia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Fil: Lomónaco, Jorgelina. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Fil: Nievas, Paula Andrea. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Fil: Chero, Paula. Quimtia. Research and Development; Perú. Fil: Lévano Gracía, Julio. Quimtia. Research and Development; Perú. Fil: Mendoza Espinoza, Alfredo. Quimtia. Research and Development; Perú.
description	Worldwide, poultry infections by Salmonella are the cause of significant economic losses, not only due to reduced production (due to fowl typhoid disease), but also considering the efforts and control measures that must be constantly applied, especially due to zoonotic serovars. Poultry is a common reservoir of Salmonella and its transmission into the food chain is a risk for humans. The vaccination of layers plays an important role in the overall efforts to prevent Salmonella infections. An inactivated trivalent vaccine was prepared with S. Enteritidis, S. Typhimurium, and S. Infantis strains. Infection trials were performed to evaluate the efficacy of three vaccination schedules using inactivated and live S. Gallinarum 9R vaccines. For this purpose, at week 5 of life, one subcutaneous dose of live S. Gallinarum 9R vaccine (1–5 × 107 CFU) was given to Groups 1 and 2. At weeks 8 and 11 of life, chickens were also vaccinated with one (Group 1) or two (Groups 2 and 3) intramuscular doses of the inactivated oil-adjuvant trivalent vaccine (1 × 108 CFU/dose of each antigen). Group 4 consisted of chickens that remained unvaccinated (control). At week 14 of life, the efficacy of the vaccination plans was evaluated in three separate inoculation trials with S. Enteritidis, S. Typhimurium, or S. Infantis. After vaccination with the inactivated vaccine, homologous antibody production was observed, and after challenge, a significant reduction in the faecal shedding, invasion, and colonization of S. Typhimurium and S. Infantis was achieved by all vaccination schedules, while the vaccination with at least one dose of the live S. Gallinarum 9R vaccine was necessary to obtain such a significant protection against S. Enteritidis infection.
publishDate	2022
dc.date.none.fl_str_mv	2022-08-05T11:13:38Z 2022-08-05T11:13:38Z 2022-07-12
dc.type.none.fl_str_mv	info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo
format	article
status_str	publishedVersion
dc.identifier.none.fl_str_mv	http://hdl.handle.net/20.500.12123/12505 https://www.mdpi.com/2076-393X/10/7/1113 2076-393X https://doi.org/10.3390/vaccines10071113
url	http://hdl.handle.net/20.500.12123/12505 https://www.mdpi.com/2076-393X/10/7/1113 https://doi.org/10.3390/vaccines10071113
identifier_str_mv	2076-393X
dc.language.none.fl_str_mv	eng
language	eng
dc.rights.none.fl_str_mv	info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv	openAccess
rights_invalid_str_mv	http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv	application/pdf
dc.publisher.none.fl_str_mv	MDPI
publisher.none.fl_str_mv	MDPI
dc.source.none.fl_str_mv	Vaccines 10 (7) : 1113 (July 2022) reponame:INTA Digital (INTA) instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str	INTA Digital (INTA)
collection	INTA Digital (INTA)
instname_str	Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv	INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv	tripaldi.nicolas@inta.gob.ar
_version_	1844619167718703104
score	12.558318

The efficacy of a trivalent inactivated salmonella vaccine combined with the live s. gallinarum 9R vaccine in young layers after experimental infections with s. enteritidis, s. typ...

Publicaciones similares