Hydroxyapatite Growth on Poly(Dimethylsiloxane-Block-ε-Caprolactone)/Tricalcium Phosphate Coatings Obtained by Electrophoretic Deposition

Autores
Redondo, Franco Leonardo; Giaroli, María Carolina; Ciolino, Andrés Eduardo; Ninago, Mario Daniel
Año de publicación
2022
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
For the first time, composite coatings based on poly(dimethylsiloxane-block-ε-caprolactone) copolymer and tricalcium phosphate were obtained on stainless steel plates by using the electrophoretic deposition technique. The effect of different deposition times on the final characteristics of the resulting coatings was also studied. Block copolymers were obtained through a combination of anionic and ring-opening polymerization, with good homogeneity and chemical composition (Ð < 1.3 and wPCL = 0.39). The composites obtained at different electrophoretic deposition times revealed a linear dependence between the deposited weight and time during assays. When immersing in simulated body fluid, a higher amount of residual solids (∼ 20 %) were observed by thermogravimetric analysis after 7 days of immersion. Scanning electron microscopy micrographs revealed a porous microstructure over the metallic substrate and the absence of micro-cracks, and X-ray diffraction patterns exhibited diffraction peaks associated with a hydroxyapatite layer. Finally, energy-dispersive X-ray analysis revealed values of the Ca/P ratio between 1.40 and 1.50 in samples, which are closer to the stoichiometric hydroxyapatite values reported in hard tissues. The results obtained in this article confirm the usefulness of poly(dimethylsiloxane-block-ε-caprolactone) copolymer and cheaper tricalcium phosphate as precursors of compact and homogenous coatings obtained by electrophoretic deposition, which yields useful substrates for hydroxyapatite growth.
Fil: Redondo, Franco Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Aplicadas A la Industria. Departamento de Ing. Química; Argentina
Fil: Giaroli, María Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Aplicadas A la Industria. Departamento de Ing. Química; Argentina
Fil: Ciolino, Andrés Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
Fil: Ninago, Mario Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Aplicadas A la Industria. Departamento de Ing. Química; Argentina
Materia
BIOACTIVITY
BLOCK COPOLYMER
ELECTROPHORETIC DEPOSITION
HYDROXYAPATITE
RING-OPENING POLYMERIZATION
TRICALCIUM PHOSPHATE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/204543
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Hydroxyapatite Growth on Poly(Dimethylsiloxane-Block-ε-Caprolactone)/Tricalcium Phosphate Coatings Obtained by Electrophoretic DepositionRedondo, Franco LeonardoGiaroli, María CarolinaCiolino, Andrés EduardoNinago, Mario DanielBIOACTIVITYBLOCK COPOLYMERELECTROPHORETIC DEPOSITIONHYDROXYAPATITERING-OPENING POLYMERIZATIONTRICALCIUM PHOSPHATEhttps://purl.org/becyt/ford/2.4https://purl.org/becyt/ford/2For the first time, composite coatings based on poly(dimethylsiloxane-block-ε-caprolactone) copolymer and tricalcium phosphate were obtained on stainless steel plates by using the electrophoretic deposition technique. The effect of different deposition times on the final characteristics of the resulting coatings was also studied. Block copolymers were obtained through a combination of anionic and ring-opening polymerization, with good homogeneity and chemical composition (Ð < 1.3 and wPCL = 0.39). The composites obtained at different electrophoretic deposition times revealed a linear dependence between the deposited weight and time during assays. When immersing in simulated body fluid, a higher amount of residual solids (∼ 20 %) were observed by thermogravimetric analysis after 7 days of immersion. Scanning electron microscopy micrographs revealed a porous microstructure over the metallic substrate and the absence of micro-cracks, and X-ray diffraction patterns exhibited diffraction peaks associated with a hydroxyapatite layer. Finally, energy-dispersive X-ray analysis revealed values of the Ca/P ratio between 1.40 and 1.50 in samples, which are closer to the stoichiometric hydroxyapatite values reported in hard tissues. The results obtained in this article confirm the usefulness of poly(dimethylsiloxane-block-ε-caprolactone) copolymer and cheaper tricalcium phosphate as precursors of compact and homogenous coatings obtained by electrophoretic deposition, which yields useful substrates for hydroxyapatite growth.Fil: Redondo, Franco Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Aplicadas A la Industria. Departamento de Ing. Química; ArgentinaFil: Giaroli, María Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Aplicadas A la Industria. Departamento de Ing. Química; ArgentinaFil: Ciolino, Andrés Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; ArgentinaFil: Ninago, Mario Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Aplicadas A la Industria. Departamento de Ing. Química; ArgentinaFrontiers Media2022-01-26info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/204543Redondo, Franco Leonardo; Giaroli, María Carolina; Ciolino, Andrés Eduardo; Ninago, Mario Daniel; Hydroxyapatite Growth on Poly(Dimethylsiloxane-Block-ε-Caprolactone)/Tricalcium Phosphate Coatings Obtained by Electrophoretic Deposition; Frontiers Media; Frontiers in Materials; 8; 26-1-2022; 1-142296-8016CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fmats.2021.803054/fullinfo:eu-repo/semantics/altIdentifier/doi/10.3389/fmats.2021.803054info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:33:51Zoai:ri.conicet.gov.ar:11336/204543instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:33:51.964CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Hydroxyapatite Growth on Poly(Dimethylsiloxane-Block-ε-Caprolactone)/Tricalcium Phosphate Coatings Obtained by Electrophoretic Deposition
title Hydroxyapatite Growth on Poly(Dimethylsiloxane-Block-ε-Caprolactone)/Tricalcium Phosphate Coatings Obtained by Electrophoretic Deposition
spellingShingle Hydroxyapatite Growth on Poly(Dimethylsiloxane-Block-ε-Caprolactone)/Tricalcium Phosphate Coatings Obtained by Electrophoretic Deposition
Redondo, Franco Leonardo
BIOACTIVITY
BLOCK COPOLYMER
ELECTROPHORETIC DEPOSITION
HYDROXYAPATITE
RING-OPENING POLYMERIZATION
TRICALCIUM PHOSPHATE
title_short Hydroxyapatite Growth on Poly(Dimethylsiloxane-Block-ε-Caprolactone)/Tricalcium Phosphate Coatings Obtained by Electrophoretic Deposition
title_full Hydroxyapatite Growth on Poly(Dimethylsiloxane-Block-ε-Caprolactone)/Tricalcium Phosphate Coatings Obtained by Electrophoretic Deposition
title_fullStr Hydroxyapatite Growth on Poly(Dimethylsiloxane-Block-ε-Caprolactone)/Tricalcium Phosphate Coatings Obtained by Electrophoretic Deposition
title_full_unstemmed Hydroxyapatite Growth on Poly(Dimethylsiloxane-Block-ε-Caprolactone)/Tricalcium Phosphate Coatings Obtained by Electrophoretic Deposition
title_sort Hydroxyapatite Growth on Poly(Dimethylsiloxane-Block-ε-Caprolactone)/Tricalcium Phosphate Coatings Obtained by Electrophoretic Deposition
dc.creator.none.fl_str_mv Redondo, Franco Leonardo
Giaroli, María Carolina
Ciolino, Andrés Eduardo
Ninago, Mario Daniel
author Redondo, Franco Leonardo
author_facet Redondo, Franco Leonardo
Giaroli, María Carolina
Ciolino, Andrés Eduardo
Ninago, Mario Daniel
author_role author
author2 Giaroli, María Carolina
Ciolino, Andrés Eduardo
Ninago, Mario Daniel
author2_role author
author
author
dc.subject.none.fl_str_mv BIOACTIVITY
BLOCK COPOLYMER
ELECTROPHORETIC DEPOSITION
HYDROXYAPATITE
RING-OPENING POLYMERIZATION
TRICALCIUM PHOSPHATE
topic BIOACTIVITY
BLOCK COPOLYMER
ELECTROPHORETIC DEPOSITION
HYDROXYAPATITE
RING-OPENING POLYMERIZATION
TRICALCIUM PHOSPHATE
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.4
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv For the first time, composite coatings based on poly(dimethylsiloxane-block-ε-caprolactone) copolymer and tricalcium phosphate were obtained on stainless steel plates by using the electrophoretic deposition technique. The effect of different deposition times on the final characteristics of the resulting coatings was also studied. Block copolymers were obtained through a combination of anionic and ring-opening polymerization, with good homogeneity and chemical composition (Ð < 1.3 and wPCL = 0.39). The composites obtained at different electrophoretic deposition times revealed a linear dependence between the deposited weight and time during assays. When immersing in simulated body fluid, a higher amount of residual solids (∼ 20 %) were observed by thermogravimetric analysis after 7 days of immersion. Scanning electron microscopy micrographs revealed a porous microstructure over the metallic substrate and the absence of micro-cracks, and X-ray diffraction patterns exhibited diffraction peaks associated with a hydroxyapatite layer. Finally, energy-dispersive X-ray analysis revealed values of the Ca/P ratio between 1.40 and 1.50 in samples, which are closer to the stoichiometric hydroxyapatite values reported in hard tissues. The results obtained in this article confirm the usefulness of poly(dimethylsiloxane-block-ε-caprolactone) copolymer and cheaper tricalcium phosphate as precursors of compact and homogenous coatings obtained by electrophoretic deposition, which yields useful substrates for hydroxyapatite growth.
Fil: Redondo, Franco Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Aplicadas A la Industria. Departamento de Ing. Química; Argentina
Fil: Giaroli, María Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Aplicadas A la Industria. Departamento de Ing. Química; Argentina
Fil: Ciolino, Andrés Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
Fil: Ninago, Mario Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Aplicadas A la Industria. Departamento de Ing. Química; Argentina
description For the first time, composite coatings based on poly(dimethylsiloxane-block-ε-caprolactone) copolymer and tricalcium phosphate were obtained on stainless steel plates by using the electrophoretic deposition technique. The effect of different deposition times on the final characteristics of the resulting coatings was also studied. Block copolymers were obtained through a combination of anionic and ring-opening polymerization, with good homogeneity and chemical composition (Ð < 1.3 and wPCL = 0.39). The composites obtained at different electrophoretic deposition times revealed a linear dependence between the deposited weight and time during assays. When immersing in simulated body fluid, a higher amount of residual solids (∼ 20 %) were observed by thermogravimetric analysis after 7 days of immersion. Scanning electron microscopy micrographs revealed a porous microstructure over the metallic substrate and the absence of micro-cracks, and X-ray diffraction patterns exhibited diffraction peaks associated with a hydroxyapatite layer. Finally, energy-dispersive X-ray analysis revealed values of the Ca/P ratio between 1.40 and 1.50 in samples, which are closer to the stoichiometric hydroxyapatite values reported in hard tissues. The results obtained in this article confirm the usefulness of poly(dimethylsiloxane-block-ε-caprolactone) copolymer and cheaper tricalcium phosphate as precursors of compact and homogenous coatings obtained by electrophoretic deposition, which yields useful substrates for hydroxyapatite growth.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-26
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/204543
Redondo, Franco Leonardo; Giaroli, María Carolina; Ciolino, Andrés Eduardo; Ninago, Mario Daniel; Hydroxyapatite Growth on Poly(Dimethylsiloxane-Block-ε-Caprolactone)/Tricalcium Phosphate Coatings Obtained by Electrophoretic Deposition; Frontiers Media; Frontiers in Materials; 8; 26-1-2022; 1-14
2296-8016
CONICET Digital
CONICET
url http://hdl.handle.net/11336/204543
identifier_str_mv Redondo, Franco Leonardo; Giaroli, María Carolina; Ciolino, Andrés Eduardo; Ninago, Mario Daniel; Hydroxyapatite Growth on Poly(Dimethylsiloxane-Block-ε-Caprolactone)/Tricalcium Phosphate Coatings Obtained by Electrophoretic Deposition; Frontiers Media; Frontiers in Materials; 8; 26-1-2022; 1-14
2296-8016
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fmats.2021.803054/full
info:eu-repo/semantics/altIdentifier/doi/10.3389/fmats.2021.803054
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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