Molecular structure effects on the post irradiation diffusion in polymer gel dosimeters
- Autores
- Mattea, Facundo; Romero, Marcelo Ricardo; Vedelago, José Alberto; Quiroga, Andrés Agustin Ignacio; Valente, Mauro Andres; Strumia, Miriam Cristina
- Año de publicación
- 2015
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Polymer gel dosimeters have specific advantages for recording 3D radiation dose distribution in diagnostic and therapeutic medical applications. A novel system based on itaconic acid and N,N?-methylene-bisacrylamide (BIS) is hereby proposed. The radical polymerization and gel formation of these monomers have been previously studied in the synthesis of a hydrogel for non dosimetric applications. Although the 3D structure of irradiated polymeric dosimeters is usually maintained for long periods of time, it is not possible to eliminate the diffusion of the different species in the regions of dose gradients within the gel. As a consequence the dose information loose quality over time. The mobility within the gelatin structure of the already mentioned species is related to their chemical structure, and nature. In this work the effect of changes in the chemical structure of the monomers over the dosimetric sensitivity and over the post-irradiation diffusion of species was studied. One of the acrylic acid groups of the itaconic acid molecule was modified to obtain molecules with similar reactivity but different molecular sizes. Dosimetric systems with these modified species were irradiated in an x-ray tomograph at different doses up to 173 Gy, and the results were characterized by Raman spectroscopy and optical absorbance in order to study their feasibility and capabilities as dosimetric systems, and by optical-CT to analyze the post irradiation diffusion.
Fil: Mattea, Facundo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; Argentina
Fil: Romero, Marcelo Ricardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina
Fil: Vedelago, José Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina
Fil: Quiroga, Andrés Agustin Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigación y Estudios de Matemática. Universidad Nacional de Córdoba. Centro de Investigación y Estudios de Matemática; Argentina
Fil: Valente, Mauro Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina
Fil: Strumia, Miriam Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina - Materia
-
Polymer Gel
Dosimetry
Radiotherapy - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/15834
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Molecular structure effects on the post irradiation diffusion in polymer gel dosimetersMattea, FacundoRomero, Marcelo RicardoVedelago, José AlbertoQuiroga, Andrés Agustin IgnacioValente, Mauro AndresStrumia, Miriam CristinaPolymer GelDosimetryRadiotherapyhttps://purl.org/becyt/ford/1.3https://purl.org/becyt/ford/1Polymer gel dosimeters have specific advantages for recording 3D radiation dose distribution in diagnostic and therapeutic medical applications. A novel system based on itaconic acid and N,N?-methylene-bisacrylamide (BIS) is hereby proposed. The radical polymerization and gel formation of these monomers have been previously studied in the synthesis of a hydrogel for non dosimetric applications. Although the 3D structure of irradiated polymeric dosimeters is usually maintained for long periods of time, it is not possible to eliminate the diffusion of the different species in the regions of dose gradients within the gel. As a consequence the dose information loose quality over time. The mobility within the gelatin structure of the already mentioned species is related to their chemical structure, and nature. In this work the effect of changes in the chemical structure of the monomers over the dosimetric sensitivity and over the post-irradiation diffusion of species was studied. One of the acrylic acid groups of the itaconic acid molecule was modified to obtain molecules with similar reactivity but different molecular sizes. Dosimetric systems with these modified species were irradiated in an x-ray tomograph at different doses up to 173 Gy, and the results were characterized by Raman spectroscopy and optical absorbance in order to study their feasibility and capabilities as dosimetric systems, and by optical-CT to analyze the post irradiation diffusion.Fil: Mattea, Facundo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; ArgentinaFil: Romero, Marcelo Ricardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; ArgentinaFil: Vedelago, José Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; ArgentinaFil: Quiroga, Andrés Agustin Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigación y Estudios de Matemática. Universidad Nacional de Córdoba. Centro de Investigación y Estudios de Matemática; ArgentinaFil: Valente, Mauro Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; ArgentinaFil: Strumia, Miriam Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; ArgentinaElsevier2015-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/15834Mattea, Facundo; Romero, Marcelo Ricardo; Vedelago, José Alberto; Quiroga, Andrés Agustin Ignacio; Valente, Mauro Andres; et al.; Molecular structure effects on the post irradiation diffusion in polymer gel dosimeters; Elsevier; Applied Radiation And Isotopes; 100; 6-2015; 101-1070969-8043enginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0969804315000779info:eu-repo/semantics/altIdentifier/doi/10.1016/j.apradiso.2015.03.007info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:04:14Zoai:ri.conicet.gov.ar:11336/15834instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:04:14.475CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Molecular structure effects on the post irradiation diffusion in polymer gel dosimeters |
title |
Molecular structure effects on the post irradiation diffusion in polymer gel dosimeters |
spellingShingle |
Molecular structure effects on the post irradiation diffusion in polymer gel dosimeters Mattea, Facundo Polymer Gel Dosimetry Radiotherapy |
title_short |
Molecular structure effects on the post irradiation diffusion in polymer gel dosimeters |
title_full |
Molecular structure effects on the post irradiation diffusion in polymer gel dosimeters |
title_fullStr |
Molecular structure effects on the post irradiation diffusion in polymer gel dosimeters |
title_full_unstemmed |
Molecular structure effects on the post irradiation diffusion in polymer gel dosimeters |
title_sort |
Molecular structure effects on the post irradiation diffusion in polymer gel dosimeters |
dc.creator.none.fl_str_mv |
Mattea, Facundo Romero, Marcelo Ricardo Vedelago, José Alberto Quiroga, Andrés Agustin Ignacio Valente, Mauro Andres Strumia, Miriam Cristina |
author |
Mattea, Facundo |
author_facet |
Mattea, Facundo Romero, Marcelo Ricardo Vedelago, José Alberto Quiroga, Andrés Agustin Ignacio Valente, Mauro Andres Strumia, Miriam Cristina |
author_role |
author |
author2 |
Romero, Marcelo Ricardo Vedelago, José Alberto Quiroga, Andrés Agustin Ignacio Valente, Mauro Andres Strumia, Miriam Cristina |
author2_role |
author author author author author |
dc.subject.none.fl_str_mv |
Polymer Gel Dosimetry Radiotherapy |
topic |
Polymer Gel Dosimetry Radiotherapy |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.3 https://purl.org/becyt/ford/1 |
dc.description.none.fl_txt_mv |
Polymer gel dosimeters have specific advantages for recording 3D radiation dose distribution in diagnostic and therapeutic medical applications. A novel system based on itaconic acid and N,N?-methylene-bisacrylamide (BIS) is hereby proposed. The radical polymerization and gel formation of these monomers have been previously studied in the synthesis of a hydrogel for non dosimetric applications. Although the 3D structure of irradiated polymeric dosimeters is usually maintained for long periods of time, it is not possible to eliminate the diffusion of the different species in the regions of dose gradients within the gel. As a consequence the dose information loose quality over time. The mobility within the gelatin structure of the already mentioned species is related to their chemical structure, and nature. In this work the effect of changes in the chemical structure of the monomers over the dosimetric sensitivity and over the post-irradiation diffusion of species was studied. One of the acrylic acid groups of the itaconic acid molecule was modified to obtain molecules with similar reactivity but different molecular sizes. Dosimetric systems with these modified species were irradiated in an x-ray tomograph at different doses up to 173 Gy, and the results were characterized by Raman spectroscopy and optical absorbance in order to study their feasibility and capabilities as dosimetric systems, and by optical-CT to analyze the post irradiation diffusion. Fil: Mattea, Facundo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; Argentina Fil: Romero, Marcelo Ricardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina Fil: Vedelago, José Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina Fil: Quiroga, Andrés Agustin Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigación y Estudios de Matemática. Universidad Nacional de Córdoba. Centro de Investigación y Estudios de Matemática; Argentina Fil: Valente, Mauro Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina Fil: Strumia, Miriam Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina |
description |
Polymer gel dosimeters have specific advantages for recording 3D radiation dose distribution in diagnostic and therapeutic medical applications. A novel system based on itaconic acid and N,N?-methylene-bisacrylamide (BIS) is hereby proposed. The radical polymerization and gel formation of these monomers have been previously studied in the synthesis of a hydrogel for non dosimetric applications. Although the 3D structure of irradiated polymeric dosimeters is usually maintained for long periods of time, it is not possible to eliminate the diffusion of the different species in the regions of dose gradients within the gel. As a consequence the dose information loose quality over time. The mobility within the gelatin structure of the already mentioned species is related to their chemical structure, and nature. In this work the effect of changes in the chemical structure of the monomers over the dosimetric sensitivity and over the post-irradiation diffusion of species was studied. One of the acrylic acid groups of the itaconic acid molecule was modified to obtain molecules with similar reactivity but different molecular sizes. Dosimetric systems with these modified species were irradiated in an x-ray tomograph at different doses up to 173 Gy, and the results were characterized by Raman spectroscopy and optical absorbance in order to study their feasibility and capabilities as dosimetric systems, and by optical-CT to analyze the post irradiation diffusion. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-06 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/15834 Mattea, Facundo; Romero, Marcelo Ricardo; Vedelago, José Alberto; Quiroga, Andrés Agustin Ignacio; Valente, Mauro Andres; et al.; Molecular structure effects on the post irradiation diffusion in polymer gel dosimeters; Elsevier; Applied Radiation And Isotopes; 100; 6-2015; 101-107 0969-8043 |
url |
http://hdl.handle.net/11336/15834 |
identifier_str_mv |
Mattea, Facundo; Romero, Marcelo Ricardo; Vedelago, José Alberto; Quiroga, Andrés Agustin Ignacio; Valente, Mauro Andres; et al.; Molecular structure effects on the post irradiation diffusion in polymer gel dosimeters; Elsevier; Applied Radiation And Isotopes; 100; 6-2015; 101-107 0969-8043 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0969804315000779 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.apradiso.2015.03.007 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf application/pdf application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
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Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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13.13397 |