Antenatal corticosteroids for preterm births in resource-limited settings - Authors' reply

Autores
Althabe, Fernando; Belizan, Jose; McClure, Elizabeth; Goldenberg, Robert L.; Buekens, Pierre
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
We have several comments regarding the letters about our study. First, Gerard Visser andGian Carlo DiRenzo state that if corticosteroids are given appropriately they can reduce perinatalmorbidity and mortality, whereas inappropriate use is likely to be harmful. However, the evidenceshowing that corticosteroids reduce neonatal morbidity and mortality are from studies done in hospitals in high-income and middle-income countries with good newborn care. By contrast, our antenatal corticosteroid trial (ACT)1 was done in low-income and middle-income countries,evidence showed no benefit with use of this drug. Therefore, the setting of where the drug is used matters.
Fil: Althabe, Fernando. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Belizan, Jose. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: McClure, Elizabeth. Research Triangle Institute International; Estados Unidos
Fil: Goldenberg, Robert L.. Columbia University; Estados Unidos
Fil: Buekens, Pierre. Tulane School of Public Health and Tropical Medicine; Estados Unidos
Materia
ANTENATAL CORTICOSTEROIDS
PRETERM BIRTHS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/113674

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network_name_str CONICET Digital (CONICET)
spelling Antenatal corticosteroids for preterm births in resource-limited settings - Authors' replyAlthabe, FernandoBelizan, JoseMcClure, ElizabethGoldenberg, Robert L.Buekens, PierreANTENATAL CORTICOSTEROIDSPRETERM BIRTHShttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3We have several comments regarding the letters about our study. First, Gerard Visser andGian Carlo DiRenzo state that if corticosteroids are given appropriately they can reduce perinatalmorbidity and mortality, whereas inappropriate use is likely to be harmful. However, the evidenceshowing that corticosteroids reduce neonatal morbidity and mortality are from studies done in hospitals in high-income and middle-income countries with good newborn care. By contrast, our antenatal corticosteroid trial (ACT)1 was done in low-income and middle-income countries,evidence showed no benefit with use of this drug. Therefore, the setting of where the drug is used matters.Fil: Althabe, Fernando. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Belizan, Jose. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: McClure, Elizabeth. Research Triangle Institute International; Estados UnidosFil: Goldenberg, Robert L.. Columbia University; Estados UnidosFil: Buekens, Pierre. Tulane School of Public Health and Tropical Medicine; Estados UnidosElsevier Science Inc2015-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/113674Althabe, Fernando; Belizan, Jose; McClure, Elizabeth; Goldenberg, Robert L.; Buekens, Pierre; Antenatal corticosteroids for preterm births in resource-limited settings - Authors' reply; Elsevier Science Inc; Lancet; 385; 9981; 5-2015; 1-10140-6736CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.thelancet.com/action/showPdf?pii=S0140-6736%2815%2960956-4info:eu-repo/semantics/altIdentifier/doi/10.1016/S0140-6736(15)60956-4info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:14:24Zoai:ri.conicet.gov.ar:11336/113674instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:14:25.262CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Antenatal corticosteroids for preterm births in resource-limited settings - Authors' reply
title Antenatal corticosteroids for preterm births in resource-limited settings - Authors' reply
spellingShingle Antenatal corticosteroids for preterm births in resource-limited settings - Authors' reply
Althabe, Fernando
ANTENATAL CORTICOSTEROIDS
PRETERM BIRTHS
title_short Antenatal corticosteroids for preterm births in resource-limited settings - Authors' reply
title_full Antenatal corticosteroids for preterm births in resource-limited settings - Authors' reply
title_fullStr Antenatal corticosteroids for preterm births in resource-limited settings - Authors' reply
title_full_unstemmed Antenatal corticosteroids for preterm births in resource-limited settings - Authors' reply
title_sort Antenatal corticosteroids for preterm births in resource-limited settings - Authors' reply
dc.creator.none.fl_str_mv Althabe, Fernando
Belizan, Jose
McClure, Elizabeth
Goldenberg, Robert L.
Buekens, Pierre
author Althabe, Fernando
author_facet Althabe, Fernando
Belizan, Jose
McClure, Elizabeth
Goldenberg, Robert L.
Buekens, Pierre
author_role author
author2 Belizan, Jose
McClure, Elizabeth
Goldenberg, Robert L.
Buekens, Pierre
author2_role author
author
author
author
dc.subject.none.fl_str_mv ANTENATAL CORTICOSTEROIDS
PRETERM BIRTHS
topic ANTENATAL CORTICOSTEROIDS
PRETERM BIRTHS
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv We have several comments regarding the letters about our study. First, Gerard Visser andGian Carlo DiRenzo state that if corticosteroids are given appropriately they can reduce perinatalmorbidity and mortality, whereas inappropriate use is likely to be harmful. However, the evidenceshowing that corticosteroids reduce neonatal morbidity and mortality are from studies done in hospitals in high-income and middle-income countries with good newborn care. By contrast, our antenatal corticosteroid trial (ACT)1 was done in low-income and middle-income countries,evidence showed no benefit with use of this drug. Therefore, the setting of where the drug is used matters.
Fil: Althabe, Fernando. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Belizan, Jose. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: McClure, Elizabeth. Research Triangle Institute International; Estados Unidos
Fil: Goldenberg, Robert L.. Columbia University; Estados Unidos
Fil: Buekens, Pierre. Tulane School of Public Health and Tropical Medicine; Estados Unidos
description We have several comments regarding the letters about our study. First, Gerard Visser andGian Carlo DiRenzo state that if corticosteroids are given appropriately they can reduce perinatalmorbidity and mortality, whereas inappropriate use is likely to be harmful. However, the evidenceshowing that corticosteroids reduce neonatal morbidity and mortality are from studies done in hospitals in high-income and middle-income countries with good newborn care. By contrast, our antenatal corticosteroid trial (ACT)1 was done in low-income and middle-income countries,evidence showed no benefit with use of this drug. Therefore, the setting of where the drug is used matters.
publishDate 2015
dc.date.none.fl_str_mv 2015-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/113674
Althabe, Fernando; Belizan, Jose; McClure, Elizabeth; Goldenberg, Robert L.; Buekens, Pierre; Antenatal corticosteroids for preterm births in resource-limited settings - Authors' reply; Elsevier Science Inc; Lancet; 385; 9981; 5-2015; 1-1
0140-6736
CONICET Digital
CONICET
url http://hdl.handle.net/11336/113674
identifier_str_mv Althabe, Fernando; Belizan, Jose; McClure, Elizabeth; Goldenberg, Robert L.; Buekens, Pierre; Antenatal corticosteroids for preterm births in resource-limited settings - Authors' reply; Elsevier Science Inc; Lancet; 385; 9981; 5-2015; 1-1
0140-6736
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
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info:eu-repo/semantics/altIdentifier/doi/10.1016/S0140-6736(15)60956-4
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science Inc
publisher.none.fl_str_mv Elsevier Science Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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