Melatonin use for SARS-CoV-2 infection: Time to diversify the treatment portfolio

Autores
Reiter, Russel; Sharma, Ramaswamy; Tan, Dun Xian; Neel, Richard L.; Simko, Fedor; Manucha, Walter Ariel Fernando; Rosales Corral, Sergio; Cardinali, Daniel Pedro
Año de publicación
2022
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
No single treatment will eliminate the COVID-19 pandemic. It is imperative that all available tactics and medications be used to overcome this disease, although it will probably never totally disappear. Melatonin is a very inexpensive molecule so it is affordable in all areas of the world, it does not require refrigeration and it has a very long shelf-life. Melatonin has no substantial side effects even at extremely high doses, no overdose has ever been achieved, and it can be self-administered via several routes. Considering its efficacy in both experimental studies and clinical trials, the portfolio of medications used to a curtail a COVID-19 infection should clearly include melatonin. Since melatonin inhibits many types of viruses, it should also be considered a potential treatment of Ebola, Zeka, and hantavirus infections.
Fil: Reiter, Russel. University Of Texas At San Antonio. University Of Texas Health Science Center At San Antonio (ut Health San Antonio); Estados Unidos
Fil: Sharma, Ramaswamy. University Of Texas At San Antonio. University Of Texas Health Science Center At San Antonio (ut Health San Antonio); Estados Unidos
Fil: Tan, Dun Xian. University Of Texas At San Antonio. University Of Texas Health Science Center At San Antonio (ut Health San Antonio); Estados Unidos
Fil: Neel, Richard L.. University Of Texas At San Antonio. University Of Texas Health Science Center At San Antonio (ut Health San Antonio); Estados Unidos
Fil: Simko, Fedor. Universidad Nacional de Cuyo; Argentina
Fil: Manucha, Walter Ariel Fernando. Universidad Nacional de Cuyo; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza; Argentina
Fil: Rosales Corral, Sergio. Instituto Mexicano del Seguro Social; México
Fil: Cardinali, Daniel Pedro. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
MELATININ
COVID-19
TREATMENT
PREVENTION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/163088

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spelling Melatonin use for SARS-CoV-2 infection: Time to diversify the treatment portfolioReiter, RusselSharma, RamaswamyTan, Dun XianNeel, Richard L.Simko, FedorManucha, Walter Ariel FernandoRosales Corral, SergioCardinali, Daniel PedroMELATININCOVID-19TREATMENTPREVENTIONhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3No single treatment will eliminate the COVID-19 pandemic. It is imperative that all available tactics and medications be used to overcome this disease, although it will probably never totally disappear. Melatonin is a very inexpensive molecule so it is affordable in all areas of the world, it does not require refrigeration and it has a very long shelf-life. Melatonin has no substantial side effects even at extremely high doses, no overdose has ever been achieved, and it can be self-administered via several routes. Considering its efficacy in both experimental studies and clinical trials, the portfolio of medications used to a curtail a COVID-19 infection should clearly include melatonin. Since melatonin inhibits many types of viruses, it should also be considered a potential treatment of Ebola, Zeka, and hantavirus infections.Fil: Reiter, Russel. University Of Texas At San Antonio. University Of Texas Health Science Center At San Antonio (ut Health San Antonio); Estados UnidosFil: Sharma, Ramaswamy. University Of Texas At San Antonio. University Of Texas Health Science Center At San Antonio (ut Health San Antonio); Estados UnidosFil: Tan, Dun Xian. University Of Texas At San Antonio. University Of Texas Health Science Center At San Antonio (ut Health San Antonio); Estados UnidosFil: Neel, Richard L.. University Of Texas At San Antonio. University Of Texas Health Science Center At San Antonio (ut Health San Antonio); Estados UnidosFil: Simko, Fedor. Universidad Nacional de Cuyo; ArgentinaFil: Manucha, Walter Ariel Fernando. Universidad Nacional de Cuyo; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza; ArgentinaFil: Rosales Corral, Sergio. Instituto Mexicano del Seguro Social; MéxicoFil: Cardinali, Daniel Pedro. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaWiley-liss, div John Wiley & Sons Inc.2022-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/163088Reiter, Russel; Sharma, Ramaswamy; Tan, Dun Xian; Neel, Richard L.; Simko, Fedor; et al.; Melatonin use for SARS-CoV-2 infection: Time to diversify the treatment portfolio; Wiley-liss, div John Wiley & Sons Inc.; Journal of Medical Virology; 94; 7; 7-2022; 2928-29300146-6615CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1002/jmv.27740info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1002/jmv.27740info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-11-12T09:43:00Zoai:ri.conicet.gov.ar:11336/163088instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-11-12 09:43:01.054CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Melatonin use for SARS-CoV-2 infection: Time to diversify the treatment portfolio
title Melatonin use for SARS-CoV-2 infection: Time to diversify the treatment portfolio
spellingShingle Melatonin use for SARS-CoV-2 infection: Time to diversify the treatment portfolio
Reiter, Russel
MELATININ
COVID-19
TREATMENT
PREVENTION
title_short Melatonin use for SARS-CoV-2 infection: Time to diversify the treatment portfolio
title_full Melatonin use for SARS-CoV-2 infection: Time to diversify the treatment portfolio
title_fullStr Melatonin use for SARS-CoV-2 infection: Time to diversify the treatment portfolio
title_full_unstemmed Melatonin use for SARS-CoV-2 infection: Time to diversify the treatment portfolio
title_sort Melatonin use for SARS-CoV-2 infection: Time to diversify the treatment portfolio
dc.creator.none.fl_str_mv Reiter, Russel
Sharma, Ramaswamy
Tan, Dun Xian
Neel, Richard L.
Simko, Fedor
Manucha, Walter Ariel Fernando
Rosales Corral, Sergio
Cardinali, Daniel Pedro
author Reiter, Russel
author_facet Reiter, Russel
Sharma, Ramaswamy
Tan, Dun Xian
Neel, Richard L.
Simko, Fedor
Manucha, Walter Ariel Fernando
Rosales Corral, Sergio
Cardinali, Daniel Pedro
author_role author
author2 Sharma, Ramaswamy
Tan, Dun Xian
Neel, Richard L.
Simko, Fedor
Manucha, Walter Ariel Fernando
Rosales Corral, Sergio
Cardinali, Daniel Pedro
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv MELATININ
COVID-19
TREATMENT
PREVENTION
topic MELATININ
COVID-19
TREATMENT
PREVENTION
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv No single treatment will eliminate the COVID-19 pandemic. It is imperative that all available tactics and medications be used to overcome this disease, although it will probably never totally disappear. Melatonin is a very inexpensive molecule so it is affordable in all areas of the world, it does not require refrigeration and it has a very long shelf-life. Melatonin has no substantial side effects even at extremely high doses, no overdose has ever been achieved, and it can be self-administered via several routes. Considering its efficacy in both experimental studies and clinical trials, the portfolio of medications used to a curtail a COVID-19 infection should clearly include melatonin. Since melatonin inhibits many types of viruses, it should also be considered a potential treatment of Ebola, Zeka, and hantavirus infections.
Fil: Reiter, Russel. University Of Texas At San Antonio. University Of Texas Health Science Center At San Antonio (ut Health San Antonio); Estados Unidos
Fil: Sharma, Ramaswamy. University Of Texas At San Antonio. University Of Texas Health Science Center At San Antonio (ut Health San Antonio); Estados Unidos
Fil: Tan, Dun Xian. University Of Texas At San Antonio. University Of Texas Health Science Center At San Antonio (ut Health San Antonio); Estados Unidos
Fil: Neel, Richard L.. University Of Texas At San Antonio. University Of Texas Health Science Center At San Antonio (ut Health San Antonio); Estados Unidos
Fil: Simko, Fedor. Universidad Nacional de Cuyo; Argentina
Fil: Manucha, Walter Ariel Fernando. Universidad Nacional de Cuyo; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza; Argentina
Fil: Rosales Corral, Sergio. Instituto Mexicano del Seguro Social; México
Fil: Cardinali, Daniel Pedro. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description No single treatment will eliminate the COVID-19 pandemic. It is imperative that all available tactics and medications be used to overcome this disease, although it will probably never totally disappear. Melatonin is a very inexpensive molecule so it is affordable in all areas of the world, it does not require refrigeration and it has a very long shelf-life. Melatonin has no substantial side effects even at extremely high doses, no overdose has ever been achieved, and it can be self-administered via several routes. Considering its efficacy in both experimental studies and clinical trials, the portfolio of medications used to a curtail a COVID-19 infection should clearly include melatonin. Since melatonin inhibits many types of viruses, it should also be considered a potential treatment of Ebola, Zeka, and hantavirus infections.
publishDate 2022
dc.date.none.fl_str_mv 2022-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/163088
Reiter, Russel; Sharma, Ramaswamy; Tan, Dun Xian; Neel, Richard L.; Simko, Fedor; et al.; Melatonin use for SARS-CoV-2 infection: Time to diversify the treatment portfolio; Wiley-liss, div John Wiley & Sons Inc.; Journal of Medical Virology; 94; 7; 7-2022; 2928-2930
0146-6615
CONICET Digital
CONICET
url http://hdl.handle.net/11336/163088
identifier_str_mv Reiter, Russel; Sharma, Ramaswamy; Tan, Dun Xian; Neel, Richard L.; Simko, Fedor; et al.; Melatonin use for SARS-CoV-2 infection: Time to diversify the treatment portfolio; Wiley-liss, div John Wiley & Sons Inc.; Journal of Medical Virology; 94; 7; 7-2022; 2928-2930
0146-6615
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1002/jmv.27740
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1002/jmv.27740
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley-liss, div John Wiley & Sons Inc.
publisher.none.fl_str_mv Wiley-liss, div John Wiley & Sons Inc.
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
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repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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