Effect of diazotated sulphonated polystyrene films on the calcium oxalate crystallization

Autores
Vásquez-Quitral, Patricio; Toledo Arana, Javier Marcelo; Miras, Maria Cristina; Acevedo, Diego Fernando; Barbero, César Alfredo; Neira-Carrillo, Andrónico
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Pathological crystallization of calcium oxalate (CaOx) inside the urinary tract is called calculi or kidney stone (Urolithiasis). CaOx exhibits three crystalline types in nature: CaOx monohydrate COM, dihydrate COD and trihydrate COT. COD and COM are often found in urinary calculi, particularly COM. Langmuir monolayers, membrane vesicles, phospholipids’ micelles, among others, have been adopted as simplified biomimetic template-models to study in vitro the urolithiasis through CaOx. The nucleation and crystal growth of COM on self-assembled lipid monolayers have revealed that the negatively charged phosphatidylserine interface is a strong promoter of COM. Herein, we describe the synthesis and physicochemical characterization of diazotated sulphonated polystyrene films (DSPFs), prepared from various aminocompounds varying their polarity degree i.e., polar, non-polar and acidic DSPF derivatives. We also used these DSPFs as polymeric templates in crystallization experiments of CaOx in vitro. Images obtained by optical microscopy and scanning electron microscopy confirmed the precipitation of COM crystals on the DSPF surface. The employment of functionalized polymeric films as templates for CaOx crystallization represents a viable approach for understanding inorganic mineralization.
Fil: Vásquez-Quitral, Patricio. Universidad de Chile; Chile
Fil: Toledo Arana, Javier Marcelo. Universidad Nacional de Rio Cuarto. Facultad de Ingeniería. Departamento de Tecnología Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Miras, Maria Cristina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina
Fil: Acevedo, Diego Fernando. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Barbero, César Alfredo. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Neira-Carrillo, Andrónico. Universidad de Chile; Chile
Materia
CALCIUM OXALATE
CRYSTALLIZATION
DIAZOTATION
POLYSTYRENE FILMS
SULPHONATION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/74671
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/74671
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Effect of diazotated sulphonated polystyrene films on the calcium oxalate crystallizationVásquez-Quitral, PatricioToledo Arana, Javier MarceloMiras, Maria CristinaAcevedo, Diego FernandoBarbero, César AlfredoNeira-Carrillo, AndrónicoCALCIUM OXALATECRYSTALLIZATIONDIAZOTATIONPOLYSTYRENE FILMSSULPHONATIONhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Pathological crystallization of calcium oxalate (CaOx) inside the urinary tract is called calculi or kidney stone (Urolithiasis). CaOx exhibits three crystalline types in nature: CaOx monohydrate COM, dihydrate COD and trihydrate COT. COD and COM are often found in urinary calculi, particularly COM. Langmuir monolayers, membrane vesicles, phospholipids’ micelles, among others, have been adopted as simplified biomimetic template-models to study in vitro the urolithiasis through CaOx. The nucleation and crystal growth of COM on self-assembled lipid monolayers have revealed that the negatively charged phosphatidylserine interface is a strong promoter of COM. Herein, we describe the synthesis and physicochemical characterization of diazotated sulphonated polystyrene films (DSPFs), prepared from various aminocompounds varying their polarity degree i.e., polar, non-polar and acidic DSPF derivatives. We also used these DSPFs as polymeric templates in crystallization experiments of CaOx in vitro. Images obtained by optical microscopy and scanning electron microscopy confirmed the precipitation of COM crystals on the DSPF surface. The employment of functionalized polymeric films as templates for CaOx crystallization represents a viable approach for understanding inorganic mineralization.Fil: Vásquez-Quitral, Patricio. Universidad de Chile; ChileFil: Toledo Arana, Javier Marcelo. Universidad Nacional de Rio Cuarto. Facultad de Ingeniería. Departamento de Tecnología Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Miras, Maria Cristina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; ArgentinaFil: Acevedo, Diego Fernando. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Barbero, César Alfredo. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Neira-Carrillo, Andrónico. Universidad de Chile; ChileMDPI AG2017-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/74671Vásquez-Quitral, Patricio; Toledo Arana, Javier Marcelo; Miras, Maria Cristina; Acevedo, Diego Fernando; Barbero, César Alfredo; et al.; Effect of diazotated sulphonated polystyrene films on the calcium oxalate crystallization; MDPI AG; Crystals; 7; 3; 3-20172073-4352CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.3390/cryst7030070info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2073-4352/7/3/70info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:43:46Zoai:ri.conicet.gov.ar:11336/74671instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:43:46.706CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Effect of diazotated sulphonated polystyrene films on the calcium oxalate crystallization
title Effect of diazotated sulphonated polystyrene films on the calcium oxalate crystallization
spellingShingle Effect of diazotated sulphonated polystyrene films on the calcium oxalate crystallization
Vásquez-Quitral, Patricio
CALCIUM OXALATE
CRYSTALLIZATION
DIAZOTATION
POLYSTYRENE FILMS
SULPHONATION
title_short Effect of diazotated sulphonated polystyrene films on the calcium oxalate crystallization
title_full Effect of diazotated sulphonated polystyrene films on the calcium oxalate crystallization
title_fullStr Effect of diazotated sulphonated polystyrene films on the calcium oxalate crystallization
title_full_unstemmed Effect of diazotated sulphonated polystyrene films on the calcium oxalate crystallization
title_sort Effect of diazotated sulphonated polystyrene films on the calcium oxalate crystallization
dc.creator.none.fl_str_mv Vásquez-Quitral, Patricio
Toledo Arana, Javier Marcelo
Miras, Maria Cristina
Acevedo, Diego Fernando
Barbero, César Alfredo
Neira-Carrillo, Andrónico
author Vásquez-Quitral, Patricio
author_facet Vásquez-Quitral, Patricio
Toledo Arana, Javier Marcelo
Miras, Maria Cristina
Acevedo, Diego Fernando
Barbero, César Alfredo
Neira-Carrillo, Andrónico
author_role author
author2 Toledo Arana, Javier Marcelo
Miras, Maria Cristina
Acevedo, Diego Fernando
Barbero, César Alfredo
Neira-Carrillo, Andrónico
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv CALCIUM OXALATE
CRYSTALLIZATION
DIAZOTATION
POLYSTYRENE FILMS
SULPHONATION
topic CALCIUM OXALATE
CRYSTALLIZATION
DIAZOTATION
POLYSTYRENE FILMS
SULPHONATION
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Pathological crystallization of calcium oxalate (CaOx) inside the urinary tract is called calculi or kidney stone (Urolithiasis). CaOx exhibits three crystalline types in nature: CaOx monohydrate COM, dihydrate COD and trihydrate COT. COD and COM are often found in urinary calculi, particularly COM. Langmuir monolayers, membrane vesicles, phospholipids’ micelles, among others, have been adopted as simplified biomimetic template-models to study in vitro the urolithiasis through CaOx. The nucleation and crystal growth of COM on self-assembled lipid monolayers have revealed that the negatively charged phosphatidylserine interface is a strong promoter of COM. Herein, we describe the synthesis and physicochemical characterization of diazotated sulphonated polystyrene films (DSPFs), prepared from various aminocompounds varying their polarity degree i.e., polar, non-polar and acidic DSPF derivatives. We also used these DSPFs as polymeric templates in crystallization experiments of CaOx in vitro. Images obtained by optical microscopy and scanning electron microscopy confirmed the precipitation of COM crystals on the DSPF surface. The employment of functionalized polymeric films as templates for CaOx crystallization represents a viable approach for understanding inorganic mineralization.
Fil: Vásquez-Quitral, Patricio. Universidad de Chile; Chile
Fil: Toledo Arana, Javier Marcelo. Universidad Nacional de Rio Cuarto. Facultad de Ingeniería. Departamento de Tecnología Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Miras, Maria Cristina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina
Fil: Acevedo, Diego Fernando. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Barbero, César Alfredo. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Neira-Carrillo, Andrónico. Universidad de Chile; Chile
description Pathological crystallization of calcium oxalate (CaOx) inside the urinary tract is called calculi or kidney stone (Urolithiasis). CaOx exhibits three crystalline types in nature: CaOx monohydrate COM, dihydrate COD and trihydrate COT. COD and COM are often found in urinary calculi, particularly COM. Langmuir monolayers, membrane vesicles, phospholipids’ micelles, among others, have been adopted as simplified biomimetic template-models to study in vitro the urolithiasis through CaOx. The nucleation and crystal growth of COM on self-assembled lipid monolayers have revealed that the negatively charged phosphatidylserine interface is a strong promoter of COM. Herein, we describe the synthesis and physicochemical characterization of diazotated sulphonated polystyrene films (DSPFs), prepared from various aminocompounds varying their polarity degree i.e., polar, non-polar and acidic DSPF derivatives. We also used these DSPFs as polymeric templates in crystallization experiments of CaOx in vitro. Images obtained by optical microscopy and scanning electron microscopy confirmed the precipitation of COM crystals on the DSPF surface. The employment of functionalized polymeric films as templates for CaOx crystallization represents a viable approach for understanding inorganic mineralization.
publishDate 2017
dc.date.none.fl_str_mv 2017-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/74671
Vásquez-Quitral, Patricio; Toledo Arana, Javier Marcelo; Miras, Maria Cristina; Acevedo, Diego Fernando; Barbero, César Alfredo; et al.; Effect of diazotated sulphonated polystyrene films on the calcium oxalate crystallization; MDPI AG; Crystals; 7; 3; 3-2017
2073-4352
CONICET Digital
CONICET
url http://hdl.handle.net/11336/74671
identifier_str_mv Vásquez-Quitral, Patricio; Toledo Arana, Javier Marcelo; Miras, Maria Cristina; Acevedo, Diego Fernando; Barbero, César Alfredo; et al.; Effect of diazotated sulphonated polystyrene films on the calcium oxalate crystallization; MDPI AG; Crystals; 7; 3; 3-2017
2073-4352
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.3390/cryst7030070
info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2073-4352/7/3/70
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv MDPI AG
publisher.none.fl_str_mv MDPI AG
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846083542372581376
score 13.22299

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