Supercritical CO2 fractionation of rosemary ethanolic oleoresins as a method to improve carnosic acid recovery

Autores
Visentin, Alexis Nahuel; Cismondi Duarte, Martín; Maestri, Damian
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Supercritical fluid antisolvent fractionation was used to obtain antioxidant compounds, mainly carnosic acid (CA), from high viscous oleoresins derived from dried rosemary leaves (Rosmarinus officinalis) extracted with ethanol. Due to the high viscosity of the starting material, which may hinder the mass transfer between the phases, a special nozzle was designed to blend the SCCO2 stream with the high viscous oleoresin. Experiments were conducted at 50 °C and six different pressures in the first separation vessel, ranging from 150 to 400 bar; the best separation was achieved at 300 bar. As a result of the oleoresin two-stage fractionation, the starting material was separated in two fractions. The first one was an insoluble dark green powder, with low concentration of CA (< 5 g/100 g extract). The other fraction was an orange colored resinous extract, very soluble in SCCO 2, with a high concentration of CA (33 g/100 g extract at 300 bar). The antioxidant effect of this extract was higher to that of BHT when added to soybean oil. Industrial relevance: The present study adds a possibility for the purification of carnosic acid from rosemary by using SCCO2 antisolvent fractionation. Since the starting material employed (oleoresin) is a fluid phase, the process might be carried out in a continuous or semi-continuous way instead of discontinuous as it should be done if the starting material were a solid (leaves). This feature makes the procedure very promising toward its application at the industrial scale.
Fil: Visentin, Alexis Nahuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ingeniería; Argentina
Fil: Cismondi Duarte, Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina
Fil: Maestri, Damian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina
Materia
Antioxidant Activity
Carnosic Acid
Ethanolic Oleoresin
Rosemary
Scco2 Antisolvent Fractionation
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/66898
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/66898
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Supercritical CO2 fractionation of rosemary ethanolic oleoresins as a method to improve carnosic acid recoveryVisentin, Alexis NahuelCismondi Duarte, MartínMaestri, DamianAntioxidant ActivityCarnosic AcidEthanolic OleoresinRosemaryScco2 Antisolvent Fractionationhttps://purl.org/becyt/ford/2.4https://purl.org/becyt/ford/2Supercritical fluid antisolvent fractionation was used to obtain antioxidant compounds, mainly carnosic acid (CA), from high viscous oleoresins derived from dried rosemary leaves (Rosmarinus officinalis) extracted with ethanol. Due to the high viscosity of the starting material, which may hinder the mass transfer between the phases, a special nozzle was designed to blend the SCCO2 stream with the high viscous oleoresin. Experiments were conducted at 50 °C and six different pressures in the first separation vessel, ranging from 150 to 400 bar; the best separation was achieved at 300 bar. As a result of the oleoresin two-stage fractionation, the starting material was separated in two fractions. The first one was an insoluble dark green powder, with low concentration of CA (< 5 g/100 g extract). The other fraction was an orange colored resinous extract, very soluble in SCCO 2, with a high concentration of CA (33 g/100 g extract at 300 bar). The antioxidant effect of this extract was higher to that of BHT when added to soybean oil. Industrial relevance: The present study adds a possibility for the purification of carnosic acid from rosemary by using SCCO2 antisolvent fractionation. Since the starting material employed (oleoresin) is a fluid phase, the process might be carried out in a continuous or semi-continuous way instead of discontinuous as it should be done if the starting material were a solid (leaves). This feature makes the procedure very promising toward its application at the industrial scale.Fil: Visentin, Alexis Nahuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ingeniería; ArgentinaFil: Cismondi Duarte, Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; ArgentinaFil: Maestri, Damian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; ArgentinaElsevier2011-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/66898Visentin, Alexis Nahuel; Cismondi Duarte, Martín; Maestri, Damian; Supercritical CO2 fractionation of rosemary ethanolic oleoresins as a method to improve carnosic acid recovery; Elsevier; Innovative Food Science & Emerging Technologies; 12; 2; 4-2011; 142-1451466-8564CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1466856411000075info:eu-repo/semantics/altIdentifier/doi/10.1016/j.ifset.2011.01.004info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:27:38Zoai:ri.conicet.gov.ar:11336/66898instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:27:38.827CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Supercritical CO2 fractionation of rosemary ethanolic oleoresins as a method to improve carnosic acid recovery
title Supercritical CO2 fractionation of rosemary ethanolic oleoresins as a method to improve carnosic acid recovery
spellingShingle Supercritical CO2 fractionation of rosemary ethanolic oleoresins as a method to improve carnosic acid recovery
Visentin, Alexis Nahuel
Antioxidant Activity
Carnosic Acid
Ethanolic Oleoresin
Rosemary
Scco2 Antisolvent Fractionation
title_short Supercritical CO2 fractionation of rosemary ethanolic oleoresins as a method to improve carnosic acid recovery
title_full Supercritical CO2 fractionation of rosemary ethanolic oleoresins as a method to improve carnosic acid recovery
title_fullStr Supercritical CO2 fractionation of rosemary ethanolic oleoresins as a method to improve carnosic acid recovery
title_full_unstemmed Supercritical CO2 fractionation of rosemary ethanolic oleoresins as a method to improve carnosic acid recovery
title_sort Supercritical CO2 fractionation of rosemary ethanolic oleoresins as a method to improve carnosic acid recovery
dc.creator.none.fl_str_mv Visentin, Alexis Nahuel
Cismondi Duarte, Martín
Maestri, Damian
author Visentin, Alexis Nahuel
author_facet Visentin, Alexis Nahuel
Cismondi Duarte, Martín
Maestri, Damian
author_role author
author2 Cismondi Duarte, Martín
Maestri, Damian
author2_role author
author
dc.subject.none.fl_str_mv Antioxidant Activity
Carnosic Acid
Ethanolic Oleoresin
Rosemary
Scco2 Antisolvent Fractionation
topic Antioxidant Activity
Carnosic Acid
Ethanolic Oleoresin
Rosemary
Scco2 Antisolvent Fractionation
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.4
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Supercritical fluid antisolvent fractionation was used to obtain antioxidant compounds, mainly carnosic acid (CA), from high viscous oleoresins derived from dried rosemary leaves (Rosmarinus officinalis) extracted with ethanol. Due to the high viscosity of the starting material, which may hinder the mass transfer between the phases, a special nozzle was designed to blend the SCCO2 stream with the high viscous oleoresin. Experiments were conducted at 50 °C and six different pressures in the first separation vessel, ranging from 150 to 400 bar; the best separation was achieved at 300 bar. As a result of the oleoresin two-stage fractionation, the starting material was separated in two fractions. The first one was an insoluble dark green powder, with low concentration of CA (< 5 g/100 g extract). The other fraction was an orange colored resinous extract, very soluble in SCCO 2, with a high concentration of CA (33 g/100 g extract at 300 bar). The antioxidant effect of this extract was higher to that of BHT when added to soybean oil. Industrial relevance: The present study adds a possibility for the purification of carnosic acid from rosemary by using SCCO2 antisolvent fractionation. Since the starting material employed (oleoresin) is a fluid phase, the process might be carried out in a continuous or semi-continuous way instead of discontinuous as it should be done if the starting material were a solid (leaves). This feature makes the procedure very promising toward its application at the industrial scale.
Fil: Visentin, Alexis Nahuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ingeniería; Argentina
Fil: Cismondi Duarte, Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina
Fil: Maestri, Damian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina
description Supercritical fluid antisolvent fractionation was used to obtain antioxidant compounds, mainly carnosic acid (CA), from high viscous oleoresins derived from dried rosemary leaves (Rosmarinus officinalis) extracted with ethanol. Due to the high viscosity of the starting material, which may hinder the mass transfer between the phases, a special nozzle was designed to blend the SCCO2 stream with the high viscous oleoresin. Experiments were conducted at 50 °C and six different pressures in the first separation vessel, ranging from 150 to 400 bar; the best separation was achieved at 300 bar. As a result of the oleoresin two-stage fractionation, the starting material was separated in two fractions. The first one was an insoluble dark green powder, with low concentration of CA (< 5 g/100 g extract). The other fraction was an orange colored resinous extract, very soluble in SCCO 2, with a high concentration of CA (33 g/100 g extract at 300 bar). The antioxidant effect of this extract was higher to that of BHT when added to soybean oil. Industrial relevance: The present study adds a possibility for the purification of carnosic acid from rosemary by using SCCO2 antisolvent fractionation. Since the starting material employed (oleoresin) is a fluid phase, the process might be carried out in a continuous or semi-continuous way instead of discontinuous as it should be done if the starting material were a solid (leaves). This feature makes the procedure very promising toward its application at the industrial scale.
publishDate 2011
dc.date.none.fl_str_mv 2011-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/66898
Visentin, Alexis Nahuel; Cismondi Duarte, Martín; Maestri, Damian; Supercritical CO2 fractionation of rosemary ethanolic oleoresins as a method to improve carnosic acid recovery; Elsevier; Innovative Food Science & Emerging Technologies; 12; 2; 4-2011; 142-145
1466-8564
CONICET Digital
CONICET
url http://hdl.handle.net/11336/66898
identifier_str_mv Visentin, Alexis Nahuel; Cismondi Duarte, Martín; Maestri, Damian; Supercritical CO2 fractionation of rosemary ethanolic oleoresins as a method to improve carnosic acid recovery; Elsevier; Innovative Food Science & Emerging Technologies; 12; 2; 4-2011; 142-145
1466-8564
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1466856411000075
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.ifset.2011.01.004
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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