Effects of Stenotic Plaques in Realistic Carotid Artery Aneurysm Models: a CFD Study
- Autores
- Castro, Marcelo Adrian; Peloc, Nora Luz; Putman, Christopher M.; Cebral, Juan Raúl
- Año de publicación
- 2014
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Cerebral aneurysms may rarely coexist with a proximal artery stenosis. In that small percent of patients, such coexistence poses a challenge for interventional neuroradiologists and neurosurgeons to make the best treatment decision. According to previous studies, the incidence of cerebral aneurysms in patients with internal carotid artery stenosis is not greater than 5%, where the aneurysm is usually incidentally detected, being 2% for aneurysms and stenoses in the same cerebral circulation. Those cases pose a difficult management decision for the physician. Case reports showed patients who died due to aneurysm rupture months after endarterectomy but before aneurysm clipping, while others did not show any change in the aneurysm after plaque removal, having optimum outcome after aneurysm coiling. The aim of this study is to investigate the intraaneurysmal hemodynamic changes before and after treatment of stenotic plaque. Virtually created moderate stenoses in vascular models of internal carotid artery aneurysm patients were considered in a number of cases reconstructed from three dimensional rotational angiography images. The strategy to create those plaques was based on parameters analyzed in a previous work where idealized models were considered, including relative distance and stenosis grade. Ipsilateral and contralateral plaques were modeled. Wall shear stress and velocity pattern were computed from finite element pulsatile blood flow simulations. The results may suggest that relative angular position may change the wall shear stress within the aneurysm sac.
Fil: Castro, Marcelo Adrian. Universidad Tecnológica Nacional. Facultad Regional Buenos Aires; Argentina. George Mason University; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Peloc, Nora Luz. Universidad Favaloro; Argentina
Fil: Putman, Christopher M.. Inova Fairfax Hospital; Estados Unidos
Fil: Cebral, Juan Raúl. George Mason University; Estados Unidos - Materia
-
Cerebral aneurysms
Stenosis
Numerical simulations
Rotational angiography - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/43028
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Effects of Stenotic Plaques in Realistic Carotid Artery Aneurysm Models: a CFD StudyCastro, Marcelo AdrianPeloc, Nora LuzPutman, Christopher M.Cebral, Juan RaúlCerebral aneurysmsStenosisNumerical simulationsRotational angiographyhttps://purl.org/becyt/ford/2.6https://purl.org/becyt/ford/2Cerebral aneurysms may rarely coexist with a proximal artery stenosis. In that small percent of patients, such coexistence poses a challenge for interventional neuroradiologists and neurosurgeons to make the best treatment decision. According to previous studies, the incidence of cerebral aneurysms in patients with internal carotid artery stenosis is not greater than 5%, where the aneurysm is usually incidentally detected, being 2% for aneurysms and stenoses in the same cerebral circulation. Those cases pose a difficult management decision for the physician. Case reports showed patients who died due to aneurysm rupture months after endarterectomy but before aneurysm clipping, while others did not show any change in the aneurysm after plaque removal, having optimum outcome after aneurysm coiling. The aim of this study is to investigate the intraaneurysmal hemodynamic changes before and after treatment of stenotic plaque. Virtually created moderate stenoses in vascular models of internal carotid artery aneurysm patients were considered in a number of cases reconstructed from three dimensional rotational angiography images. The strategy to create those plaques was based on parameters analyzed in a previous work where idealized models were considered, including relative distance and stenosis grade. Ipsilateral and contralateral plaques were modeled. Wall shear stress and velocity pattern were computed from finite element pulsatile blood flow simulations. The results may suggest that relative angular position may change the wall shear stress within the aneurysm sac.Fil: Castro, Marcelo Adrian. Universidad Tecnológica Nacional. Facultad Regional Buenos Aires; Argentina. George Mason University; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Peloc, Nora Luz. Universidad Favaloro; ArgentinaFil: Putman, Christopher M.. Inova Fairfax Hospital; Estados UnidosFil: Cebral, Juan Raúl. George Mason University; Estados UnidosAsociación Argentina de Mecánica Computacional2014-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/43028Castro, Marcelo Adrian; Peloc, Nora Luz; Putman, Christopher M.; Cebral, Juan Raúl; Effects of Stenotic Plaques in Realistic Carotid Artery Aneurysm Models: a CFD Study; Asociación Argentina de Mecánica Computacional; Mecánica Computacional; XXXIII; 41; 9-2014; 2677-26872591-3522CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://cimec.org.ar/ojs/index.php/mc/article/view/4861info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:33:19Zoai:ri.conicet.gov.ar:11336/43028instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:33:19.765CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Effects of Stenotic Plaques in Realistic Carotid Artery Aneurysm Models: a CFD Study |
title |
Effects of Stenotic Plaques in Realistic Carotid Artery Aneurysm Models: a CFD Study |
spellingShingle |
Effects of Stenotic Plaques in Realistic Carotid Artery Aneurysm Models: a CFD Study Castro, Marcelo Adrian Cerebral aneurysms Stenosis Numerical simulations Rotational angiography |
title_short |
Effects of Stenotic Plaques in Realistic Carotid Artery Aneurysm Models: a CFD Study |
title_full |
Effects of Stenotic Plaques in Realistic Carotid Artery Aneurysm Models: a CFD Study |
title_fullStr |
Effects of Stenotic Plaques in Realistic Carotid Artery Aneurysm Models: a CFD Study |
title_full_unstemmed |
Effects of Stenotic Plaques in Realistic Carotid Artery Aneurysm Models: a CFD Study |
title_sort |
Effects of Stenotic Plaques in Realistic Carotid Artery Aneurysm Models: a CFD Study |
dc.creator.none.fl_str_mv |
Castro, Marcelo Adrian Peloc, Nora Luz Putman, Christopher M. Cebral, Juan Raúl |
author |
Castro, Marcelo Adrian |
author_facet |
Castro, Marcelo Adrian Peloc, Nora Luz Putman, Christopher M. Cebral, Juan Raúl |
author_role |
author |
author2 |
Peloc, Nora Luz Putman, Christopher M. Cebral, Juan Raúl |
author2_role |
author author author |
dc.subject.none.fl_str_mv |
Cerebral aneurysms Stenosis Numerical simulations Rotational angiography |
topic |
Cerebral aneurysms Stenosis Numerical simulations Rotational angiography |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/2.6 https://purl.org/becyt/ford/2 |
dc.description.none.fl_txt_mv |
Cerebral aneurysms may rarely coexist with a proximal artery stenosis. In that small percent of patients, such coexistence poses a challenge for interventional neuroradiologists and neurosurgeons to make the best treatment decision. According to previous studies, the incidence of cerebral aneurysms in patients with internal carotid artery stenosis is not greater than 5%, where the aneurysm is usually incidentally detected, being 2% for aneurysms and stenoses in the same cerebral circulation. Those cases pose a difficult management decision for the physician. Case reports showed patients who died due to aneurysm rupture months after endarterectomy but before aneurysm clipping, while others did not show any change in the aneurysm after plaque removal, having optimum outcome after aneurysm coiling. The aim of this study is to investigate the intraaneurysmal hemodynamic changes before and after treatment of stenotic plaque. Virtually created moderate stenoses in vascular models of internal carotid artery aneurysm patients were considered in a number of cases reconstructed from three dimensional rotational angiography images. The strategy to create those plaques was based on parameters analyzed in a previous work where idealized models were considered, including relative distance and stenosis grade. Ipsilateral and contralateral plaques were modeled. Wall shear stress and velocity pattern were computed from finite element pulsatile blood flow simulations. The results may suggest that relative angular position may change the wall shear stress within the aneurysm sac. Fil: Castro, Marcelo Adrian. Universidad Tecnológica Nacional. Facultad Regional Buenos Aires; Argentina. George Mason University; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Peloc, Nora Luz. Universidad Favaloro; Argentina Fil: Putman, Christopher M.. Inova Fairfax Hospital; Estados Unidos Fil: Cebral, Juan Raúl. George Mason University; Estados Unidos |
description |
Cerebral aneurysms may rarely coexist with a proximal artery stenosis. In that small percent of patients, such coexistence poses a challenge for interventional neuroradiologists and neurosurgeons to make the best treatment decision. According to previous studies, the incidence of cerebral aneurysms in patients with internal carotid artery stenosis is not greater than 5%, where the aneurysm is usually incidentally detected, being 2% for aneurysms and stenoses in the same cerebral circulation. Those cases pose a difficult management decision for the physician. Case reports showed patients who died due to aneurysm rupture months after endarterectomy but before aneurysm clipping, while others did not show any change in the aneurysm after plaque removal, having optimum outcome after aneurysm coiling. The aim of this study is to investigate the intraaneurysmal hemodynamic changes before and after treatment of stenotic plaque. Virtually created moderate stenoses in vascular models of internal carotid artery aneurysm patients were considered in a number of cases reconstructed from three dimensional rotational angiography images. The strategy to create those plaques was based on parameters analyzed in a previous work where idealized models were considered, including relative distance and stenosis grade. Ipsilateral and contralateral plaques were modeled. Wall shear stress and velocity pattern were computed from finite element pulsatile blood flow simulations. The results may suggest that relative angular position may change the wall shear stress within the aneurysm sac. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-09 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/43028 Castro, Marcelo Adrian; Peloc, Nora Luz; Putman, Christopher M.; Cebral, Juan Raúl; Effects of Stenotic Plaques in Realistic Carotid Artery Aneurysm Models: a CFD Study; Asociación Argentina de Mecánica Computacional; Mecánica Computacional; XXXIII; 41; 9-2014; 2677-2687 2591-3522 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/43028 |
identifier_str_mv |
Castro, Marcelo Adrian; Peloc, Nora Luz; Putman, Christopher M.; Cebral, Juan Raúl; Effects of Stenotic Plaques in Realistic Carotid Artery Aneurysm Models: a CFD Study; Asociación Argentina de Mecánica Computacional; Mecánica Computacional; XXXIII; 41; 9-2014; 2677-2687 2591-3522 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/https://cimec.org.ar/ojs/index.php/mc/article/view/4861 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Asociación Argentina de Mecánica Computacional |
publisher.none.fl_str_mv |
Asociación Argentina de Mecánica Computacional |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1844614348510593024 |
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13.070432 |