Comparative genomics uncovers unique gene turnover and evolutionary rates in a gene family involved in the detection of insect cuticular pheromones

Autores
Torres Oliva, Montserrat; Cunha Almeida, Francisca; Sánchez Gracia, Alejandro; Rozas, Julio
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Chemoreception is an essential process for the survival and reproduction of animals. Many of the proteins responsible for recognizing and transmitting chemical stimuli in insects are encoded by genes that are members of moderately sized multigene families. The members of the CheB family are specialized in gustatory-mediated detection of long-chain hydrocarbon pheromones in Drosophila melanogaster and play a central role in triggering and modulating mating behavior in this species. Here, we present a comprehensive comparative genomic analysis of the CheB family across 12 species of the Drosophila genus. We have identified a total of 102 new CheB genes in the genomes of these species, including a functionally divergent member previously uncharacterized in D. melanogaster. We found that, despite its relatively small repertory size, the CheB family has undergone multiple gain and loss events and various episodes of diversifying selection during the divergence of the surveyed species. Present estimates of gene turnover and coding sequence substitution rates show that this family is evolving faster than any known Drosophila chemosensory family. To date, only other insect gustatory-related genes among these families had shown evolutionary dynamics close to those observed in CheBs. Our findings reveal the high adaptive potential of molecular components of the gustatory system in insects and anticipate a key role of genes involved in this sensory modality in species adaptation and diversification.
Fil: Torres Oliva, Montserrat. Universidad de Barcelona; España. Johann Friedrich Blumenbach Institute for Zoology and Anthropology; Alemania
Fil: Cunha Almeida, Francisca. Universidad de Barcelona; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Sánchez Gracia, Alejandro. Universidad de Barcelona; España
Fil: Rozas, Julio. Universidad de Barcelona; España
Materia
BIRTH
CHEB GENE FAMILY
CHEMOSENSORY PROTEINS
DEATH EVOLUTION
FUNCTIONAL DIVERGENCE
POSITIVE SELECTION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/61434
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Comparative genomics uncovers unique gene turnover and evolutionary rates in a gene family involved in the detection of insect cuticular pheromonesTorres Oliva, MontserratCunha Almeida, FranciscaSánchez Gracia, AlejandroRozas, JulioBIRTHCHEB GENE FAMILYCHEMOSENSORY PROTEINSDEATH EVOLUTIONFUNCTIONAL DIVERGENCEPOSITIVE SELECTIONhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Chemoreception is an essential process for the survival and reproduction of animals. Many of the proteins responsible for recognizing and transmitting chemical stimuli in insects are encoded by genes that are members of moderately sized multigene families. The members of the CheB family are specialized in gustatory-mediated detection of long-chain hydrocarbon pheromones in Drosophila melanogaster and play a central role in triggering and modulating mating behavior in this species. Here, we present a comprehensive comparative genomic analysis of the CheB family across 12 species of the Drosophila genus. We have identified a total of 102 new CheB genes in the genomes of these species, including a functionally divergent member previously uncharacterized in D. melanogaster. We found that, despite its relatively small repertory size, the CheB family has undergone multiple gain and loss events and various episodes of diversifying selection during the divergence of the surveyed species. Present estimates of gene turnover and coding sequence substitution rates show that this family is evolving faster than any known Drosophila chemosensory family. To date, only other insect gustatory-related genes among these families had shown evolutionary dynamics close to those observed in CheBs. Our findings reveal the high adaptive potential of molecular components of the gustatory system in insects and anticipate a key role of genes involved in this sensory modality in species adaptation and diversification.Fil: Torres Oliva, Montserrat. Universidad de Barcelona; España. Johann Friedrich Blumenbach Institute for Zoology and Anthropology; AlemaniaFil: Cunha Almeida, Francisca. Universidad de Barcelona; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Ecología, Genética y Evolución de Buenos Aires; ArgentinaFil: Sánchez Gracia, Alejandro. Universidad de Barcelona; EspañaFil: Rozas, Julio. Universidad de Barcelona; EspañaOxford University Press2016-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/61434Torres Oliva, Montserrat; Cunha Almeida, Francisca; Sánchez Gracia, Alejandro; Rozas, Julio; Comparative genomics uncovers unique gene turnover and evolutionary rates in a gene family involved in the detection of insect cuticular pheromones; Oxford University Press; Genome Biology and Evolution; 8; 6; 7-2016; 1734-17471759-6653CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1093/gbe/evw108info:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/gbe/article/8/6/1734/2574014info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:40:15Zoai:ri.conicet.gov.ar:11336/61434instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:40:16.06CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Comparative genomics uncovers unique gene turnover and evolutionary rates in a gene family involved in the detection of insect cuticular pheromones
title Comparative genomics uncovers unique gene turnover and evolutionary rates in a gene family involved in the detection of insect cuticular pheromones
spellingShingle Comparative genomics uncovers unique gene turnover and evolutionary rates in a gene family involved in the detection of insect cuticular pheromones
Torres Oliva, Montserrat
BIRTH
CHEB GENE FAMILY
CHEMOSENSORY PROTEINS
DEATH EVOLUTION
FUNCTIONAL DIVERGENCE
POSITIVE SELECTION
title_short Comparative genomics uncovers unique gene turnover and evolutionary rates in a gene family involved in the detection of insect cuticular pheromones
title_full Comparative genomics uncovers unique gene turnover and evolutionary rates in a gene family involved in the detection of insect cuticular pheromones
title_fullStr Comparative genomics uncovers unique gene turnover and evolutionary rates in a gene family involved in the detection of insect cuticular pheromones
title_full_unstemmed Comparative genomics uncovers unique gene turnover and evolutionary rates in a gene family involved in the detection of insect cuticular pheromones
title_sort Comparative genomics uncovers unique gene turnover and evolutionary rates in a gene family involved in the detection of insect cuticular pheromones
dc.creator.none.fl_str_mv Torres Oliva, Montserrat
Cunha Almeida, Francisca
Sánchez Gracia, Alejandro
Rozas, Julio
author Torres Oliva, Montserrat
author_facet Torres Oliva, Montserrat
Cunha Almeida, Francisca
Sánchez Gracia, Alejandro
Rozas, Julio
author_role author
author2 Cunha Almeida, Francisca
Sánchez Gracia, Alejandro
Rozas, Julio
author2_role author
author
author
dc.subject.none.fl_str_mv BIRTH
CHEB GENE FAMILY
CHEMOSENSORY PROTEINS
DEATH EVOLUTION
FUNCTIONAL DIVERGENCE
POSITIVE SELECTION
topic BIRTH
CHEB GENE FAMILY
CHEMOSENSORY PROTEINS
DEATH EVOLUTION
FUNCTIONAL DIVERGENCE
POSITIVE SELECTION
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Chemoreception is an essential process for the survival and reproduction of animals. Many of the proteins responsible for recognizing and transmitting chemical stimuli in insects are encoded by genes that are members of moderately sized multigene families. The members of the CheB family are specialized in gustatory-mediated detection of long-chain hydrocarbon pheromones in Drosophila melanogaster and play a central role in triggering and modulating mating behavior in this species. Here, we present a comprehensive comparative genomic analysis of the CheB family across 12 species of the Drosophila genus. We have identified a total of 102 new CheB genes in the genomes of these species, including a functionally divergent member previously uncharacterized in D. melanogaster. We found that, despite its relatively small repertory size, the CheB family has undergone multiple gain and loss events and various episodes of diversifying selection during the divergence of the surveyed species. Present estimates of gene turnover and coding sequence substitution rates show that this family is evolving faster than any known Drosophila chemosensory family. To date, only other insect gustatory-related genes among these families had shown evolutionary dynamics close to those observed in CheBs. Our findings reveal the high adaptive potential of molecular components of the gustatory system in insects and anticipate a key role of genes involved in this sensory modality in species adaptation and diversification.
Fil: Torres Oliva, Montserrat. Universidad de Barcelona; España. Johann Friedrich Blumenbach Institute for Zoology and Anthropology; Alemania
Fil: Cunha Almeida, Francisca. Universidad de Barcelona; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Sánchez Gracia, Alejandro. Universidad de Barcelona; España
Fil: Rozas, Julio. Universidad de Barcelona; España
description Chemoreception is an essential process for the survival and reproduction of animals. Many of the proteins responsible for recognizing and transmitting chemical stimuli in insects are encoded by genes that are members of moderately sized multigene families. The members of the CheB family are specialized in gustatory-mediated detection of long-chain hydrocarbon pheromones in Drosophila melanogaster and play a central role in triggering and modulating mating behavior in this species. Here, we present a comprehensive comparative genomic analysis of the CheB family across 12 species of the Drosophila genus. We have identified a total of 102 new CheB genes in the genomes of these species, including a functionally divergent member previously uncharacterized in D. melanogaster. We found that, despite its relatively small repertory size, the CheB family has undergone multiple gain and loss events and various episodes of diversifying selection during the divergence of the surveyed species. Present estimates of gene turnover and coding sequence substitution rates show that this family is evolving faster than any known Drosophila chemosensory family. To date, only other insect gustatory-related genes among these families had shown evolutionary dynamics close to those observed in CheBs. Our findings reveal the high adaptive potential of molecular components of the gustatory system in insects and anticipate a key role of genes involved in this sensory modality in species adaptation and diversification.
publishDate 2016
dc.date.none.fl_str_mv 2016-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/61434
Torres Oliva, Montserrat; Cunha Almeida, Francisca; Sánchez Gracia, Alejandro; Rozas, Julio; Comparative genomics uncovers unique gene turnover and evolutionary rates in a gene family involved in the detection of insect cuticular pheromones; Oxford University Press; Genome Biology and Evolution; 8; 6; 7-2016; 1734-1747
1759-6653
CONICET Digital
CONICET
url http://hdl.handle.net/11336/61434
identifier_str_mv Torres Oliva, Montserrat; Cunha Almeida, Francisca; Sánchez Gracia, Alejandro; Rozas, Julio; Comparative genomics uncovers unique gene turnover and evolutionary rates in a gene family involved in the detection of insect cuticular pheromones; Oxford University Press; Genome Biology and Evolution; 8; 6; 7-2016; 1734-1747
1759-6653
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1093/gbe/evw108
info:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/gbe/article/8/6/1734/2574014
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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