A new venomous scorpion responsible for severe envenomation in Argentina: Tityus confluens
- Autores
- de Roodt, Adolfo Rafael; Lago, Néstor Rubén; Salomón, Oscar Daniel; Laskowicz, Rodrigo Daniel; Neder, Lilia Estela; López, Raúl Alfredo; Montero, Teresa Eleonor; Vega, Valeria del Valle
- Año de publicación
- 2009
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- In Argentina the scorpions of medical importance belong to the genus Tityus (T.), particularly the species T. trivittatus, the only scorpion whose sting is recognized to be associated with severe human envenoming and death. This genus is distributed from the north of the Patagonian region to the center and some provinces in the north of the country. During the period 2003-2006 four children died following scorpion stings, of which one was certainly and three were probably by T. confluens. In 2006, in the province of Tucumán, a girl died by scorpion envenoming and the scorpion responsible for the death, found in her shoe, was T. confluens. We thus studied the toxicity of venom gland homogenates from T. confluens from the provinces of Jujuy and Catamarca, and of crude venom from specimens from Catamarca and the province of La Rioja. The lethal potencies of the telson homogenates were 7.0 and 18.6 μg/g for Jujuy and Catamarca, respectively, while the lethal potency of the crude venom was 0.7 μg/g. Injected mice showed generalized congestion and hepatic lesions. Pancreatic damage was observed in some animals. Lungs showed congestion and foci of hemorrhage and mild edema. The heart showed injury in the muscular fibers. The venom showed high reactivity against anti-T. trivittatus antivenom and against two anti-T. serrulatus antivenoms. The anti-T. trivittatus antivenom neutralized the lethal activity of T. confluens venom. In addition, the venom reacted very slightly against an anti-Centruroides antivenom. Therefore, the stings of this scorpion must be considered of risk for humans to the same degree as the stings of T. trivittatus
Fil: de Roodt, Adolfo Rafael. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud “Dr. C. G. Malbrán”; Argentina
Fil: Lago, Néstor Rubén. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Patología. Centro de Patología Experimental; Argentina
Fil: Salomón, Oscar Daniel. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud “Dr. C. G. Malbrán”; Argentina. Ministerio de Salud. Instituto Nacional de Medicina Tropical; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; Argentina
Fil: Laskowicz, Rodrigo Daniel. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud “Dr. C. G. Malbrán”; Argentina
Fil: Neder, Lilia Estela. Universidad Nacional de Jujuy. Instituto de Biología de la Altura; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Jujuy. Universidad Nacional de Jujuy. Centro de Investigaciones y Transferencia de Jujuy; Argentina
Fil: López, Raúl Alfredo. Provincia de Catamarca; Argentina
Fil: Montero, Teresa Eleonor. Universidad Nacional de Jujuy. Instituto de Biología de la Altura; Argentina
Fil: Vega, Valeria del Valle. Universidad Nacional de Tucumán. Facultad de Ciencias Naturales e Instituto Miguel Lillo; Argentina - Materia
-
Envenomation
Scorpion
Toxicity
Venom - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/61305
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A new venomous scorpion responsible for severe envenomation in Argentina: Tityus confluensde Roodt, Adolfo RafaelLago, Néstor RubénSalomón, Oscar DanielLaskowicz, Rodrigo DanielNeder, Lilia EstelaLópez, Raúl AlfredoMontero, Teresa EleonorVega, Valeria del ValleEnvenomationScorpionToxicityVenomhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3In Argentina the scorpions of medical importance belong to the genus Tityus (T.), particularly the species T. trivittatus, the only scorpion whose sting is recognized to be associated with severe human envenoming and death. This genus is distributed from the north of the Patagonian region to the center and some provinces in the north of the country. During the period 2003-2006 four children died following scorpion stings, of which one was certainly and three were probably by T. confluens. In 2006, in the province of Tucumán, a girl died by scorpion envenoming and the scorpion responsible for the death, found in her shoe, was T. confluens. We thus studied the toxicity of venom gland homogenates from T. confluens from the provinces of Jujuy and Catamarca, and of crude venom from specimens from Catamarca and the province of La Rioja. The lethal potencies of the telson homogenates were 7.0 and 18.6 μg/g for Jujuy and Catamarca, respectively, while the lethal potency of the crude venom was 0.7 μg/g. Injected mice showed generalized congestion and hepatic lesions. Pancreatic damage was observed in some animals. Lungs showed congestion and foci of hemorrhage and mild edema. The heart showed injury in the muscular fibers. The venom showed high reactivity against anti-T. trivittatus antivenom and against two anti-T. serrulatus antivenoms. The anti-T. trivittatus antivenom neutralized the lethal activity of T. confluens venom. In addition, the venom reacted very slightly against an anti-Centruroides antivenom. Therefore, the stings of this scorpion must be considered of risk for humans to the same degree as the stings of T. trivittatusFil: de Roodt, Adolfo Rafael. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud “Dr. C. G. Malbrán”; ArgentinaFil: Lago, Néstor Rubén. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Patología. Centro de Patología Experimental; ArgentinaFil: Salomón, Oscar Daniel. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud “Dr. C. G. Malbrán”; Argentina. Ministerio de Salud. Instituto Nacional de Medicina Tropical; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; ArgentinaFil: Laskowicz, Rodrigo Daniel. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud “Dr. C. G. Malbrán”; ArgentinaFil: Neder, Lilia Estela. Universidad Nacional de Jujuy. Instituto de Biología de la Altura; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Jujuy. Universidad Nacional de Jujuy. Centro de Investigaciones y Transferencia de Jujuy; ArgentinaFil: López, Raúl Alfredo. Provincia de Catamarca; ArgentinaFil: Montero, Teresa Eleonor. Universidad Nacional de Jujuy. Instituto de Biología de la Altura; ArgentinaFil: Vega, Valeria del Valle. Universidad Nacional de Tucumán. Facultad de Ciencias Naturales e Instituto Miguel Lillo; ArgentinaPergamon-Elsevier Science Ltd2009-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/61305de Roodt, Adolfo Rafael; Lago, Néstor Rubén; Salomón, Oscar Daniel; Laskowicz, Rodrigo Daniel; Neder, Lilia Estela; et al.; A new venomous scorpion responsible for severe envenomation in Argentina: Tityus confluens; Pergamon-Elsevier Science Ltd; Toxicon; 53; 1; 1-2009; 1-80041-01011879-3150CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.toxicon.2008.10.003info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0041010108005485info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:42:21Zoai:ri.conicet.gov.ar:11336/61305instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:42:21.707CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
A new venomous scorpion responsible for severe envenomation in Argentina: Tityus confluens |
title |
A new venomous scorpion responsible for severe envenomation in Argentina: Tityus confluens |
spellingShingle |
A new venomous scorpion responsible for severe envenomation in Argentina: Tityus confluens de Roodt, Adolfo Rafael Envenomation Scorpion Toxicity Venom |
title_short |
A new venomous scorpion responsible for severe envenomation in Argentina: Tityus confluens |
title_full |
A new venomous scorpion responsible for severe envenomation in Argentina: Tityus confluens |
title_fullStr |
A new venomous scorpion responsible for severe envenomation in Argentina: Tityus confluens |
title_full_unstemmed |
A new venomous scorpion responsible for severe envenomation in Argentina: Tityus confluens |
title_sort |
A new venomous scorpion responsible for severe envenomation in Argentina: Tityus confluens |
dc.creator.none.fl_str_mv |
de Roodt, Adolfo Rafael Lago, Néstor Rubén Salomón, Oscar Daniel Laskowicz, Rodrigo Daniel Neder, Lilia Estela López, Raúl Alfredo Montero, Teresa Eleonor Vega, Valeria del Valle |
author |
de Roodt, Adolfo Rafael |
author_facet |
de Roodt, Adolfo Rafael Lago, Néstor Rubén Salomón, Oscar Daniel Laskowicz, Rodrigo Daniel Neder, Lilia Estela López, Raúl Alfredo Montero, Teresa Eleonor Vega, Valeria del Valle |
author_role |
author |
author2 |
Lago, Néstor Rubén Salomón, Oscar Daniel Laskowicz, Rodrigo Daniel Neder, Lilia Estela López, Raúl Alfredo Montero, Teresa Eleonor Vega, Valeria del Valle |
author2_role |
author author author author author author author |
dc.subject.none.fl_str_mv |
Envenomation Scorpion Toxicity Venom |
topic |
Envenomation Scorpion Toxicity Venom |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.1 https://purl.org/becyt/ford/3 |
dc.description.none.fl_txt_mv |
In Argentina the scorpions of medical importance belong to the genus Tityus (T.), particularly the species T. trivittatus, the only scorpion whose sting is recognized to be associated with severe human envenoming and death. This genus is distributed from the north of the Patagonian region to the center and some provinces in the north of the country. During the period 2003-2006 four children died following scorpion stings, of which one was certainly and three were probably by T. confluens. In 2006, in the province of Tucumán, a girl died by scorpion envenoming and the scorpion responsible for the death, found in her shoe, was T. confluens. We thus studied the toxicity of venom gland homogenates from T. confluens from the provinces of Jujuy and Catamarca, and of crude venom from specimens from Catamarca and the province of La Rioja. The lethal potencies of the telson homogenates were 7.0 and 18.6 μg/g for Jujuy and Catamarca, respectively, while the lethal potency of the crude venom was 0.7 μg/g. Injected mice showed generalized congestion and hepatic lesions. Pancreatic damage was observed in some animals. Lungs showed congestion and foci of hemorrhage and mild edema. The heart showed injury in the muscular fibers. The venom showed high reactivity against anti-T. trivittatus antivenom and against two anti-T. serrulatus antivenoms. The anti-T. trivittatus antivenom neutralized the lethal activity of T. confluens venom. In addition, the venom reacted very slightly against an anti-Centruroides antivenom. Therefore, the stings of this scorpion must be considered of risk for humans to the same degree as the stings of T. trivittatus Fil: de Roodt, Adolfo Rafael. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud “Dr. C. G. Malbrán”; Argentina Fil: Lago, Néstor Rubén. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Patología. Centro de Patología Experimental; Argentina Fil: Salomón, Oscar Daniel. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud “Dr. C. G. Malbrán”; Argentina. Ministerio de Salud. Instituto Nacional de Medicina Tropical; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; Argentina Fil: Laskowicz, Rodrigo Daniel. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud “Dr. C. G. Malbrán”; Argentina Fil: Neder, Lilia Estela. Universidad Nacional de Jujuy. Instituto de Biología de la Altura; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Jujuy. Universidad Nacional de Jujuy. Centro de Investigaciones y Transferencia de Jujuy; Argentina Fil: López, Raúl Alfredo. Provincia de Catamarca; Argentina Fil: Montero, Teresa Eleonor. Universidad Nacional de Jujuy. Instituto de Biología de la Altura; Argentina Fil: Vega, Valeria del Valle. Universidad Nacional de Tucumán. Facultad de Ciencias Naturales e Instituto Miguel Lillo; Argentina |
description |
In Argentina the scorpions of medical importance belong to the genus Tityus (T.), particularly the species T. trivittatus, the only scorpion whose sting is recognized to be associated with severe human envenoming and death. This genus is distributed from the north of the Patagonian region to the center and some provinces in the north of the country. During the period 2003-2006 four children died following scorpion stings, of which one was certainly and three were probably by T. confluens. In 2006, in the province of Tucumán, a girl died by scorpion envenoming and the scorpion responsible for the death, found in her shoe, was T. confluens. We thus studied the toxicity of venom gland homogenates from T. confluens from the provinces of Jujuy and Catamarca, and of crude venom from specimens from Catamarca and the province of La Rioja. The lethal potencies of the telson homogenates were 7.0 and 18.6 μg/g for Jujuy and Catamarca, respectively, while the lethal potency of the crude venom was 0.7 μg/g. Injected mice showed generalized congestion and hepatic lesions. Pancreatic damage was observed in some animals. Lungs showed congestion and foci of hemorrhage and mild edema. The heart showed injury in the muscular fibers. The venom showed high reactivity against anti-T. trivittatus antivenom and against two anti-T. serrulatus antivenoms. The anti-T. trivittatus antivenom neutralized the lethal activity of T. confluens venom. In addition, the venom reacted very slightly against an anti-Centruroides antivenom. Therefore, the stings of this scorpion must be considered of risk for humans to the same degree as the stings of T. trivittatus |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-01 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/61305 de Roodt, Adolfo Rafael; Lago, Néstor Rubén; Salomón, Oscar Daniel; Laskowicz, Rodrigo Daniel; Neder, Lilia Estela; et al.; A new venomous scorpion responsible for severe envenomation in Argentina: Tityus confluens; Pergamon-Elsevier Science Ltd; Toxicon; 53; 1; 1-2009; 1-8 0041-0101 1879-3150 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/61305 |
identifier_str_mv |
de Roodt, Adolfo Rafael; Lago, Néstor Rubén; Salomón, Oscar Daniel; Laskowicz, Rodrigo Daniel; Neder, Lilia Estela; et al.; A new venomous scorpion responsible for severe envenomation in Argentina: Tityus confluens; Pergamon-Elsevier Science Ltd; Toxicon; 53; 1; 1-2009; 1-8 0041-0101 1879-3150 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.toxicon.2008.10.003 info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0041010108005485 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf application/pdf application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Pergamon-Elsevier Science Ltd |
publisher.none.fl_str_mv |
Pergamon-Elsevier Science Ltd |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
_version_ |
1844614456314691584 |
score |
13.070432 |