Throat carriage rate and antimicrobial resistance of streptococcus pyogenes in rural children in Argentina

Autores
Delpech, Gastón; Sparo, Mónica Delfina; Baldaccini, Maria Beatriz; Pourcel, Natalia Gisela; Lissarrague, Sabina; Allende, Leonardo García
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Objectives: The aim of this study was to determine the prevalence of asymptomatic carriers of group A β-hemolytic streptococci (GAS) in children living in a rural community and to investigate the association between episodes of acute pharyngitis and carrier status. Methods: Throat swabs were collected from September to November 2013 among children 5-13 years of age from a rural community (Maria Ignacia-Vela, Argentina). The phenotypic characterization of isolates was performed by conventional tests. Antimicrobial susceptibility was assayed for penicillin, tetracycline, chloramphenicol, erythromycin, and clindamycin (disk diffusion). The minimum inhibitory concentration was determined for penicillin, cefotaxime, tetracycline, and erythromycin. Results: The carriage of β-hemolytic streptococci was detected in 18.1% of participants, with Streptococcus pyogenes in 18 participants followed by S. dysgalactiae ssp. equisimilis in 5. The highest proportion of GAS was found in 8 to 10-year-old children. No significant association between the number of episodes of acute pharyngitis suffered in the last year and the carrier state was detected (p>0.05). Tetracycline resistance (55.5%) and macrolide-resistant phenotypes (11.1%) were observed. Resistance to penicillin, cefotaxime, or chloramphenicol was not expressed in any streptococcal isolate. Conclusions: The present study demonstrated significant throat carriage of GAS and the presence of group C streptococci (S. dysgalactiae ssp. equisimilis) in an Argentinian rural population. These results point out the need for continuous surveillance of GAS and non-GAS carriage as well as of antimicrobial resistance in highly susceptible populations, such as school-Aged rural children. An extended surveillance program including school-Aged children from different cities should be considered to estimate the prevalence of GAS carriage in Argentina.
Fil: Delpech, Gastón. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires; Argentina
Fil: Sparo, Mónica Delfina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires; Argentina. Hospital Ramón Santamarina; Argentina
Fil: Baldaccini, Maria Beatriz. Universidad Nacional del Centro de la Provincia de Buenos Aires; Argentina
Fil: Pourcel, Natalia Gisela. Universidad Nacional del Centro de la Provincia de Buenos Aires; Argentina
Fil: Lissarrague, Sabina. Hospital Ramón Santamarina; Argentina
Fil: Allende, Leonardo García. Centro de Estudios Bioquímicos; Argentina
Materia
Argentina
Pharyngitis
Prevalence
Rural Population
Streptococcus Pyogenes
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/65962
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/65962
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Throat carriage rate and antimicrobial resistance of streptococcus pyogenes in rural children in ArgentinaDelpech, GastónSparo, Mónica DelfinaBaldaccini, Maria BeatrizPourcel, Natalia GiselaLissarrague, SabinaAllende, Leonardo GarcíaArgentinaPharyngitisPrevalenceRural PopulationStreptococcus Pyogeneshttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Objectives: The aim of this study was to determine the prevalence of asymptomatic carriers of group A β-hemolytic streptococci (GAS) in children living in a rural community and to investigate the association between episodes of acute pharyngitis and carrier status. Methods: Throat swabs were collected from September to November 2013 among children 5-13 years of age from a rural community (Maria Ignacia-Vela, Argentina). The phenotypic characterization of isolates was performed by conventional tests. Antimicrobial susceptibility was assayed for penicillin, tetracycline, chloramphenicol, erythromycin, and clindamycin (disk diffusion). The minimum inhibitory concentration was determined for penicillin, cefotaxime, tetracycline, and erythromycin. Results: The carriage of β-hemolytic streptococci was detected in 18.1% of participants, with Streptococcus pyogenes in 18 participants followed by S. dysgalactiae ssp. equisimilis in 5. The highest proportion of GAS was found in 8 to 10-year-old children. No significant association between the number of episodes of acute pharyngitis suffered in the last year and the carrier state was detected (p>0.05). Tetracycline resistance (55.5%) and macrolide-resistant phenotypes (11.1%) were observed. Resistance to penicillin, cefotaxime, or chloramphenicol was not expressed in any streptococcal isolate. Conclusions: The present study demonstrated significant throat carriage of GAS and the presence of group C streptococci (S. dysgalactiae ssp. equisimilis) in an Argentinian rural population. These results point out the need for continuous surveillance of GAS and non-GAS carriage as well as of antimicrobial resistance in highly susceptible populations, such as school-Aged rural children. An extended surveillance program including school-Aged children from different cities should be considered to estimate the prevalence of GAS carriage in Argentina.Fil: Delpech, Gastón. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires; ArgentinaFil: Sparo, Mónica Delfina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires; Argentina. Hospital Ramón Santamarina; ArgentinaFil: Baldaccini, Maria Beatriz. Universidad Nacional del Centro de la Provincia de Buenos Aires; ArgentinaFil: Pourcel, Natalia Gisela. Universidad Nacional del Centro de la Provincia de Buenos Aires; ArgentinaFil: Lissarrague, Sabina. Hospital Ramón Santamarina; ArgentinaFil: Allende, Leonardo García. Centro de Estudios Bioquímicos; ArgentinaKorean Society for Preventive Medicine2017-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/65962Delpech, Gastón; Sparo, Mónica Delfina; Baldaccini, Maria Beatriz; Pourcel, Natalia Gisela; Lissarrague, Sabina; et al.; Throat carriage rate and antimicrobial resistance of streptococcus pyogenes in rural children in Argentina; Korean Society for Preventive Medicine; Journal of Preventive Medicine and Public Health; 50; 2; 3-2017; 127-1321975-83752233-4521CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.3961/jpmph.15.073info:eu-repo/semantics/altIdentifier/url/https://www.jpmph.org/journal/view.php?doi=10.3961/jpmph.15.073info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:46:28Zoai:ri.conicet.gov.ar:11336/65962instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:46:28.918CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Throat carriage rate and antimicrobial resistance of streptococcus pyogenes in rural children in Argentina
title Throat carriage rate and antimicrobial resistance of streptococcus pyogenes in rural children in Argentina
spellingShingle Throat carriage rate and antimicrobial resistance of streptococcus pyogenes in rural children in Argentina
Delpech, Gastón
Argentina
Pharyngitis
Prevalence
Rural Population
Streptococcus Pyogenes
title_short Throat carriage rate and antimicrobial resistance of streptococcus pyogenes in rural children in Argentina
title_full Throat carriage rate and antimicrobial resistance of streptococcus pyogenes in rural children in Argentina
title_fullStr Throat carriage rate and antimicrobial resistance of streptococcus pyogenes in rural children in Argentina
title_full_unstemmed Throat carriage rate and antimicrobial resistance of streptococcus pyogenes in rural children in Argentina
title_sort Throat carriage rate and antimicrobial resistance of streptococcus pyogenes in rural children in Argentina
dc.creator.none.fl_str_mv Delpech, Gastón
Sparo, Mónica Delfina
Baldaccini, Maria Beatriz
Pourcel, Natalia Gisela
Lissarrague, Sabina
Allende, Leonardo García
author Delpech, Gastón
author_facet Delpech, Gastón
Sparo, Mónica Delfina
Baldaccini, Maria Beatriz
Pourcel, Natalia Gisela
Lissarrague, Sabina
Allende, Leonardo García
author_role author
author2 Sparo, Mónica Delfina
Baldaccini, Maria Beatriz
Pourcel, Natalia Gisela
Lissarrague, Sabina
Allende, Leonardo García
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Argentina
Pharyngitis
Prevalence
Rural Population
Streptococcus Pyogenes
topic Argentina
Pharyngitis
Prevalence
Rural Population
Streptococcus Pyogenes
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Objectives: The aim of this study was to determine the prevalence of asymptomatic carriers of group A β-hemolytic streptococci (GAS) in children living in a rural community and to investigate the association between episodes of acute pharyngitis and carrier status. Methods: Throat swabs were collected from September to November 2013 among children 5-13 years of age from a rural community (Maria Ignacia-Vela, Argentina). The phenotypic characterization of isolates was performed by conventional tests. Antimicrobial susceptibility was assayed for penicillin, tetracycline, chloramphenicol, erythromycin, and clindamycin (disk diffusion). The minimum inhibitory concentration was determined for penicillin, cefotaxime, tetracycline, and erythromycin. Results: The carriage of β-hemolytic streptococci was detected in 18.1% of participants, with Streptococcus pyogenes in 18 participants followed by S. dysgalactiae ssp. equisimilis in 5. The highest proportion of GAS was found in 8 to 10-year-old children. No significant association between the number of episodes of acute pharyngitis suffered in the last year and the carrier state was detected (p>0.05). Tetracycline resistance (55.5%) and macrolide-resistant phenotypes (11.1%) were observed. Resistance to penicillin, cefotaxime, or chloramphenicol was not expressed in any streptococcal isolate. Conclusions: The present study demonstrated significant throat carriage of GAS and the presence of group C streptococci (S. dysgalactiae ssp. equisimilis) in an Argentinian rural population. These results point out the need for continuous surveillance of GAS and non-GAS carriage as well as of antimicrobial resistance in highly susceptible populations, such as school-Aged rural children. An extended surveillance program including school-Aged children from different cities should be considered to estimate the prevalence of GAS carriage in Argentina.
Fil: Delpech, Gastón. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires; Argentina
Fil: Sparo, Mónica Delfina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires; Argentina. Hospital Ramón Santamarina; Argentina
Fil: Baldaccini, Maria Beatriz. Universidad Nacional del Centro de la Provincia de Buenos Aires; Argentina
Fil: Pourcel, Natalia Gisela. Universidad Nacional del Centro de la Provincia de Buenos Aires; Argentina
Fil: Lissarrague, Sabina. Hospital Ramón Santamarina; Argentina
Fil: Allende, Leonardo García. Centro de Estudios Bioquímicos; Argentina
description Objectives: The aim of this study was to determine the prevalence of asymptomatic carriers of group A β-hemolytic streptococci (GAS) in children living in a rural community and to investigate the association between episodes of acute pharyngitis and carrier status. Methods: Throat swabs were collected from September to November 2013 among children 5-13 years of age from a rural community (Maria Ignacia-Vela, Argentina). The phenotypic characterization of isolates was performed by conventional tests. Antimicrobial susceptibility was assayed for penicillin, tetracycline, chloramphenicol, erythromycin, and clindamycin (disk diffusion). The minimum inhibitory concentration was determined for penicillin, cefotaxime, tetracycline, and erythromycin. Results: The carriage of β-hemolytic streptococci was detected in 18.1% of participants, with Streptococcus pyogenes in 18 participants followed by S. dysgalactiae ssp. equisimilis in 5. The highest proportion of GAS was found in 8 to 10-year-old children. No significant association between the number of episodes of acute pharyngitis suffered in the last year and the carrier state was detected (p>0.05). Tetracycline resistance (55.5%) and macrolide-resistant phenotypes (11.1%) were observed. Resistance to penicillin, cefotaxime, or chloramphenicol was not expressed in any streptococcal isolate. Conclusions: The present study demonstrated significant throat carriage of GAS and the presence of group C streptococci (S. dysgalactiae ssp. equisimilis) in an Argentinian rural population. These results point out the need for continuous surveillance of GAS and non-GAS carriage as well as of antimicrobial resistance in highly susceptible populations, such as school-Aged rural children. An extended surveillance program including school-Aged children from different cities should be considered to estimate the prevalence of GAS carriage in Argentina.
publishDate 2017
dc.date.none.fl_str_mv 2017-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/65962
Delpech, Gastón; Sparo, Mónica Delfina; Baldaccini, Maria Beatriz; Pourcel, Natalia Gisela; Lissarrague, Sabina; et al.; Throat carriage rate and antimicrobial resistance of streptococcus pyogenes in rural children in Argentina; Korean Society for Preventive Medicine; Journal of Preventive Medicine and Public Health; 50; 2; 3-2017; 127-132
1975-8375
2233-4521
CONICET Digital
CONICET
url http://hdl.handle.net/11336/65962
identifier_str_mv Delpech, Gastón; Sparo, Mónica Delfina; Baldaccini, Maria Beatriz; Pourcel, Natalia Gisela; Lissarrague, Sabina; et al.; Throat carriage rate and antimicrobial resistance of streptococcus pyogenes in rural children in Argentina; Korean Society for Preventive Medicine; Journal of Preventive Medicine and Public Health; 50; 2; 3-2017; 127-132
1975-8375
2233-4521
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.3961/jpmph.15.073
info:eu-repo/semantics/altIdentifier/url/https://www.jpmph.org/journal/view.php?doi=10.3961/jpmph.15.073
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Korean Society for Preventive Medicine
publisher.none.fl_str_mv Korean Society for Preventive Medicine
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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