Proteomic Strategies for the Analysis of Carbonyl Groups on Proteins

Autores
Irazusta, Verónica Patricia; Moreno Cermeño, Armando; Cabiscol, Elisa; Tamarit, Jordi; Ros, Joaquim
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Oxidative stress is caused by an imbalance between formation and destruction of reactive oxygen species. Analysis of the reaction products of reactive oxygen species in biomolecules is an indirect way of determining the existence of oxidative stress. In this context, the formation of carbonyl groups in proteins has been one of the most studied oxidative stress markers because of its stability and easy detection. Various proteomic tools offer great potential for the discovery of new proteins susceptible to oxidative stress, determination of quantitative changes in the profile of these modifications under different biological conditions, and characterization of the type of modification a particular protein has suffered. This paper reviews the different approaches used for the detection of protein carbonyls and the proteomic tools that can be used to identify them.
Fil: Irazusta, Verónica Patricia. Universidad de Lleida. Instituto de Recerca Biomédica; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina
Fil: Moreno Cermeño, Armando. Universidad de Lleida. Instituto de Recerca Biomédica; España
Fil: Cabiscol, Elisa. Universidad de Lleida. Instituto de Recerca Biomédica; España
Fil: Tamarit, Jordi. Universidad de Lleida. Instituto de Recerca Biomédica; España
Fil: Ros, Joaquim. Universidad de Lleida. Instituto de Recerca Biomédica; España
Materia
Oxidative Stress
Protein Oxidation
Carbonyl Group
Redox Proteomics
Huntington Disease
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/40762
Acceder
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spelling Proteomic Strategies for the Analysis of Carbonyl Groups on ProteinsIrazusta, Verónica PatriciaMoreno Cermeño, ArmandoCabiscol, ElisaTamarit, JordiRos, JoaquimOxidative StressProtein OxidationCarbonyl GroupRedox ProteomicsHuntington Diseasehttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Oxidative stress is caused by an imbalance between formation and destruction of reactive oxygen species. Analysis of the reaction products of reactive oxygen species in biomolecules is an indirect way of determining the existence of oxidative stress. In this context, the formation of carbonyl groups in proteins has been one of the most studied oxidative stress markers because of its stability and easy detection. Various proteomic tools offer great potential for the discovery of new proteins susceptible to oxidative stress, determination of quantitative changes in the profile of these modifications under different biological conditions, and characterization of the type of modification a particular protein has suffered. This paper reviews the different approaches used for the detection of protein carbonyls and the proteomic tools that can be used to identify them.Fil: Irazusta, Verónica Patricia. Universidad de Lleida. Instituto de Recerca Biomédica; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; ArgentinaFil: Moreno Cermeño, Armando. Universidad de Lleida. Instituto de Recerca Biomédica; EspañaFil: Cabiscol, Elisa. Universidad de Lleida. Instituto de Recerca Biomédica; EspañaFil: Tamarit, Jordi. Universidad de Lleida. Instituto de Recerca Biomédica; EspañaFil: Ros, Joaquim. Universidad de Lleida. Instituto de Recerca Biomédica; EspañaBentham Science Publishers2010-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/40762Irazusta, Verónica Patricia; Moreno Cermeño, Armando; Cabiscol, Elisa; Tamarit, Jordi; Ros, Joaquim; Proteomic Strategies for the Analysis of Carbonyl Groups on Proteins; Bentham Science Publishers; Current Protein and Peptide Science; 11; 8; 12-2010; 652-6581389-2037CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.2174/138920310794557664info:eu-repo/semantics/altIdentifier/url/http://www.eurekaselect.com/87246/articleinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:00:08Zoai:ri.conicet.gov.ar:11336/40762instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:00:08.537CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Proteomic Strategies for the Analysis of Carbonyl Groups on Proteins
title Proteomic Strategies for the Analysis of Carbonyl Groups on Proteins
spellingShingle Proteomic Strategies for the Analysis of Carbonyl Groups on Proteins
Irazusta, Verónica Patricia
Oxidative Stress
Protein Oxidation
Carbonyl Group
Redox Proteomics
Huntington Disease
title_short Proteomic Strategies for the Analysis of Carbonyl Groups on Proteins
title_full Proteomic Strategies for the Analysis of Carbonyl Groups on Proteins
title_fullStr Proteomic Strategies for the Analysis of Carbonyl Groups on Proteins
title_full_unstemmed Proteomic Strategies for the Analysis of Carbonyl Groups on Proteins
title_sort Proteomic Strategies for the Analysis of Carbonyl Groups on Proteins
dc.creator.none.fl_str_mv Irazusta, Verónica Patricia
Moreno Cermeño, Armando
Cabiscol, Elisa
Tamarit, Jordi
Ros, Joaquim
author Irazusta, Verónica Patricia
author_facet Irazusta, Verónica Patricia
Moreno Cermeño, Armando
Cabiscol, Elisa
Tamarit, Jordi
Ros, Joaquim
author_role author
author2 Moreno Cermeño, Armando
Cabiscol, Elisa
Tamarit, Jordi
Ros, Joaquim
author2_role author
author
author
author
dc.subject.none.fl_str_mv Oxidative Stress
Protein Oxidation
Carbonyl Group
Redox Proteomics
Huntington Disease
topic Oxidative Stress
Protein Oxidation
Carbonyl Group
Redox Proteomics
Huntington Disease
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Oxidative stress is caused by an imbalance between formation and destruction of reactive oxygen species. Analysis of the reaction products of reactive oxygen species in biomolecules is an indirect way of determining the existence of oxidative stress. In this context, the formation of carbonyl groups in proteins has been one of the most studied oxidative stress markers because of its stability and easy detection. Various proteomic tools offer great potential for the discovery of new proteins susceptible to oxidative stress, determination of quantitative changes in the profile of these modifications under different biological conditions, and characterization of the type of modification a particular protein has suffered. This paper reviews the different approaches used for the detection of protein carbonyls and the proteomic tools that can be used to identify them.
Fil: Irazusta, Verónica Patricia. Universidad de Lleida. Instituto de Recerca Biomédica; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina
Fil: Moreno Cermeño, Armando. Universidad de Lleida. Instituto de Recerca Biomédica; España
Fil: Cabiscol, Elisa. Universidad de Lleida. Instituto de Recerca Biomédica; España
Fil: Tamarit, Jordi. Universidad de Lleida. Instituto de Recerca Biomédica; España
Fil: Ros, Joaquim. Universidad de Lleida. Instituto de Recerca Biomédica; España
description Oxidative stress is caused by an imbalance between formation and destruction of reactive oxygen species. Analysis of the reaction products of reactive oxygen species in biomolecules is an indirect way of determining the existence of oxidative stress. In this context, the formation of carbonyl groups in proteins has been one of the most studied oxidative stress markers because of its stability and easy detection. Various proteomic tools offer great potential for the discovery of new proteins susceptible to oxidative stress, determination of quantitative changes in the profile of these modifications under different biological conditions, and characterization of the type of modification a particular protein has suffered. This paper reviews the different approaches used for the detection of protein carbonyls and the proteomic tools that can be used to identify them.
publishDate 2010
dc.date.none.fl_str_mv 2010-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/40762
Irazusta, Verónica Patricia; Moreno Cermeño, Armando; Cabiscol, Elisa; Tamarit, Jordi; Ros, Joaquim; Proteomic Strategies for the Analysis of Carbonyl Groups on Proteins; Bentham Science Publishers; Current Protein and Peptide Science; 11; 8; 12-2010; 652-658
1389-2037
CONICET Digital
CONICET
url http://hdl.handle.net/11336/40762
identifier_str_mv Irazusta, Verónica Patricia; Moreno Cermeño, Armando; Cabiscol, Elisa; Tamarit, Jordi; Ros, Joaquim; Proteomic Strategies for the Analysis of Carbonyl Groups on Proteins; Bentham Science Publishers; Current Protein and Peptide Science; 11; 8; 12-2010; 652-658
1389-2037
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.2174/138920310794557664
info:eu-repo/semantics/altIdentifier/url/http://www.eurekaselect.com/87246/article
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Bentham Science Publishers
publisher.none.fl_str_mv Bentham Science Publishers
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.885934

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