Refractive and topographic corneal changes associated with increased inflammatory mediators in tears after COVID-19

Autores
Reviglio, Victor Eduardo; Almada, Laura; Paz, Maria Constanza; Sanchez, Maria Cecilia; Osaba, Matías; Acosta Rodríguez, Victoria América; Strusberg, Ingrid
Año de publicación
2024
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
This is a rare case report of a sudden shift to myopic astigmatism and topography alterations in a patient who experienced mild coronavirus disease 2019 (COVID‑19) symptoms. A complete ophthalmologic evaluation, slit‑lamp examination, corneal topography, and tear sampling for biochemical analysis were performed. Elevated corneal K‑values were found, indicating abnormal anterior corneal curvature, based on the asymmetric corneal steepening index (cone location and magnitude index) in a Galilei G6 study. Tear analysis demonstrated elevated levels of interleukin (IL)‑1β, IL‑6, IP‑10, IL‑8, interferon‑β, and prometalloproteinase‑9. Ophthalmologists should maintain a high level of suspicion when symptoms suggestive of corneal involvement arise in patients recently infected with severe acute respiratory syndrome coronavirus 2.
Fil: Reviglio, Victor Eduardo. Sanatorio Allende; Argentina. Cerro Vision Institute; Argentina. Universidad Católica de Córdoba; Argentina
Fil: Almada, Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina
Fil: Paz, Maria Constanza. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina
Fil: Sanchez, Maria Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina
Fil: Osaba, Matías. Sanatorio Allende; Argentina. Cerro Vision Institute; Argentina. Universidad Católica de Córdoba; Argentina
Fil: Acosta Rodríguez, Victoria América. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina
Fil: Strusberg, Ingrid. Universidad Nacional de Córdoba. Facultad de Medicina; Argentina
Materia
CORONAVIRUS
IRREGULAR ASTGMATISM
MYOPIA
SARS-COV-2
TEAR CYTOKINES
TEAR PRO-MMP-9
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/267700
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Refractive and topographic corneal changes associated with increased inflammatory mediators in tears after COVID-19Reviglio, Victor EduardoAlmada, LauraPaz, Maria ConstanzaSanchez, Maria CeciliaOsaba, MatíasAcosta Rodríguez, Victoria AméricaStrusberg, IngridCORONAVIRUSIRREGULAR ASTGMATISMMYOPIASARS-COV-2TEAR CYTOKINESTEAR PRO-MMP-9https://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3This is a rare case report of a sudden shift to myopic astigmatism and topography alterations in a patient who experienced mild coronavirus disease 2019 (COVID‑19) symptoms. A complete ophthalmologic evaluation, slit‑lamp examination, corneal topography, and tear sampling for biochemical analysis were performed. Elevated corneal K‑values were found, indicating abnormal anterior corneal curvature, based on the asymmetric corneal steepening index (cone location and magnitude index) in a Galilei G6 study. Tear analysis demonstrated elevated levels of interleukin (IL)‑1β, IL‑6, IP‑10, IL‑8, interferon‑β, and prometalloproteinase‑9. Ophthalmologists should maintain a high level of suspicion when symptoms suggestive of corneal involvement arise in patients recently infected with severe acute respiratory syndrome coronavirus 2.Fil: Reviglio, Victor Eduardo. Sanatorio Allende; Argentina. Cerro Vision Institute; Argentina. Universidad Católica de Córdoba; ArgentinaFil: Almada, Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaFil: Paz, Maria Constanza. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaFil: Sanchez, Maria Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaFil: Osaba, Matías. Sanatorio Allende; Argentina. Cerro Vision Institute; Argentina. Universidad Católica de Córdoba; ArgentinaFil: Acosta Rodríguez, Victoria América. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaFil: Strusberg, Ingrid. Universidad Nacional de Córdoba. Facultad de Medicina; ArgentinaAll India Ophthalmological Soc2024-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/267700Reviglio, Victor Eduardo; Almada, Laura; Paz, Maria Constanza; Sanchez, Maria Cecilia; Osaba, Matías; et al.; Refractive and topographic corneal changes associated with increased inflammatory mediators in tears after COVID-19; All India Ophthalmological Soc; Indian Journal of Ophthalmology - Case Reports; 4; 3; 7-2024; 692-6960301-47382772-3089CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://journals.lww.com/ijog/fulltext/2024/04030/refractive_and_topographic_corneal_changes.33.aspxinfo:eu-repo/semantics/altIdentifier/doi/10.4103/IJO.IJO_221_24info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:20:47Zoai:ri.conicet.gov.ar:11336/267700instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:20:47.597CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Refractive and topographic corneal changes associated with increased inflammatory mediators in tears after COVID-19
title Refractive and topographic corneal changes associated with increased inflammatory mediators in tears after COVID-19
spellingShingle Refractive and topographic corneal changes associated with increased inflammatory mediators in tears after COVID-19
Reviglio, Victor Eduardo
CORONAVIRUS
IRREGULAR ASTGMATISM
MYOPIA
SARS-COV-2
TEAR CYTOKINES
TEAR PRO-MMP-9
title_short Refractive and topographic corneal changes associated with increased inflammatory mediators in tears after COVID-19
title_full Refractive and topographic corneal changes associated with increased inflammatory mediators in tears after COVID-19
title_fullStr Refractive and topographic corneal changes associated with increased inflammatory mediators in tears after COVID-19
title_full_unstemmed Refractive and topographic corneal changes associated with increased inflammatory mediators in tears after COVID-19
title_sort Refractive and topographic corneal changes associated with increased inflammatory mediators in tears after COVID-19
dc.creator.none.fl_str_mv Reviglio, Victor Eduardo
Almada, Laura
Paz, Maria Constanza
Sanchez, Maria Cecilia
Osaba, Matías
Acosta Rodríguez, Victoria América
Strusberg, Ingrid
author Reviglio, Victor Eduardo
author_facet Reviglio, Victor Eduardo
Almada, Laura
Paz, Maria Constanza
Sanchez, Maria Cecilia
Osaba, Matías
Acosta Rodríguez, Victoria América
Strusberg, Ingrid
author_role author
author2 Almada, Laura
Paz, Maria Constanza
Sanchez, Maria Cecilia
Osaba, Matías
Acosta Rodríguez, Victoria América
Strusberg, Ingrid
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv CORONAVIRUS
IRREGULAR ASTGMATISM
MYOPIA
SARS-COV-2
TEAR CYTOKINES
TEAR PRO-MMP-9
topic CORONAVIRUS
IRREGULAR ASTGMATISM
MYOPIA
SARS-COV-2
TEAR CYTOKINES
TEAR PRO-MMP-9
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv This is a rare case report of a sudden shift to myopic astigmatism and topography alterations in a patient who experienced mild coronavirus disease 2019 (COVID‑19) symptoms. A complete ophthalmologic evaluation, slit‑lamp examination, corneal topography, and tear sampling for biochemical analysis were performed. Elevated corneal K‑values were found, indicating abnormal anterior corneal curvature, based on the asymmetric corneal steepening index (cone location and magnitude index) in a Galilei G6 study. Tear analysis demonstrated elevated levels of interleukin (IL)‑1β, IL‑6, IP‑10, IL‑8, interferon‑β, and prometalloproteinase‑9. Ophthalmologists should maintain a high level of suspicion when symptoms suggestive of corneal involvement arise in patients recently infected with severe acute respiratory syndrome coronavirus 2.
Fil: Reviglio, Victor Eduardo. Sanatorio Allende; Argentina. Cerro Vision Institute; Argentina. Universidad Católica de Córdoba; Argentina
Fil: Almada, Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina
Fil: Paz, Maria Constanza. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina
Fil: Sanchez, Maria Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina
Fil: Osaba, Matías. Sanatorio Allende; Argentina. Cerro Vision Institute; Argentina. Universidad Católica de Córdoba; Argentina
Fil: Acosta Rodríguez, Victoria América. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina
Fil: Strusberg, Ingrid. Universidad Nacional de Córdoba. Facultad de Medicina; Argentina
description This is a rare case report of a sudden shift to myopic astigmatism and topography alterations in a patient who experienced mild coronavirus disease 2019 (COVID‑19) symptoms. A complete ophthalmologic evaluation, slit‑lamp examination, corneal topography, and tear sampling for biochemical analysis were performed. Elevated corneal K‑values were found, indicating abnormal anterior corneal curvature, based on the asymmetric corneal steepening index (cone location and magnitude index) in a Galilei G6 study. Tear analysis demonstrated elevated levels of interleukin (IL)‑1β, IL‑6, IP‑10, IL‑8, interferon‑β, and prometalloproteinase‑9. Ophthalmologists should maintain a high level of suspicion when symptoms suggestive of corneal involvement arise in patients recently infected with severe acute respiratory syndrome coronavirus 2.
publishDate 2024
dc.date.none.fl_str_mv 2024-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/267700
Reviglio, Victor Eduardo; Almada, Laura; Paz, Maria Constanza; Sanchez, Maria Cecilia; Osaba, Matías; et al.; Refractive and topographic corneal changes associated with increased inflammatory mediators in tears after COVID-19; All India Ophthalmological Soc; Indian Journal of Ophthalmology - Case Reports; 4; 3; 7-2024; 692-696
0301-4738
2772-3089
CONICET Digital
CONICET
url http://hdl.handle.net/11336/267700
identifier_str_mv Reviglio, Victor Eduardo; Almada, Laura; Paz, Maria Constanza; Sanchez, Maria Cecilia; Osaba, Matías; et al.; Refractive and topographic corneal changes associated with increased inflammatory mediators in tears after COVID-19; All India Ophthalmological Soc; Indian Journal of Ophthalmology - Case Reports; 4; 3; 7-2024; 692-696
0301-4738
2772-3089
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://journals.lww.com/ijog/fulltext/2024/04030/refractive_and_topographic_corneal_changes.33.aspx
info:eu-repo/semantics/altIdentifier/doi/10.4103/IJO.IJO_221_24
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv All India Ophthalmological Soc
publisher.none.fl_str_mv All India Ophthalmological Soc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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