Whole-cell biosensors: research and patents

Autores
Fernandez, Marcelo Raul; Bernik, Delia Leticia
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In the last ten years several research articles and patents related to the obtaining and uses of whole-cell biosen- sors (WCB) have been published. Whole-cell sensors, whole-cell biosensors, chemical sensors, integrated sensors and bioreporters (among others) are the main terms used to define a living cell machinery adapted to detect target analytes at low concentration levels. The methods for constructing and detection technologies for these WCB could be very diverse. Some of them include a foreign nucleic acid sequence to act as reporter, to regulate the reporter’s expression or both. But some other inventors ex- ploit the natural properties of organisms without the need of genetic engineering. Another aspect is the localization of the cell at the moment of use. Some inventors, depending on the method of detection, need cells in a special location, such as the surface of a detector, entrapped in a matrix, or in the bulk of the sample. This review intends to compile the most rele- vant patents related to WCB which enable to illustrate the above mentioned cases of these new types of biosensors.
Fil: Fernandez, Marcelo Raul. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química, Física de los Materiales, Medioambiente y Energía. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química, Física de los Materiales, Medioambiente y Energía; Argentina
Fil: Bernik, Delia Leticia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química, Física de los Materiales, Medioambiente y Energía. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química, Física de los Materiales, Medioambiente y Energía; Argentina
Materia
Bioreporters
Whole-Cell Biosensors
Living Sensors
Integrated Sensors
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/71754
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Whole-cell biosensors: research and patentsFernandez, Marcelo RaulBernik, Delia LeticiaBioreportersWhole-Cell BiosensorsLiving SensorsIntegrated Sensorshttps://purl.org/becyt/ford/2.8https://purl.org/becyt/ford/2In the last ten years several research articles and patents related to the obtaining and uses of whole-cell biosen- sors (WCB) have been published. Whole-cell sensors, whole-cell biosensors, chemical sensors, integrated sensors and bioreporters (among others) are the main terms used to define a living cell machinery adapted to detect target analytes at low concentration levels. The methods for constructing and detection technologies for these WCB could be very diverse. Some of them include a foreign nucleic acid sequence to act as reporter, to regulate the reporter’s expression or both. But some other inventors ex- ploit the natural properties of organisms without the need of genetic engineering. Another aspect is the localization of the cell at the moment of use. Some inventors, depending on the method of detection, need cells in a special location, such as the surface of a detector, entrapped in a matrix, or in the bulk of the sample. This review intends to compile the most rele- vant patents related to WCB which enable to illustrate the above mentioned cases of these new types of biosensors.Fil: Fernandez, Marcelo Raul. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química, Física de los Materiales, Medioambiente y Energía. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química, Física de los Materiales, Medioambiente y Energía; ArgentinaFil: Bernik, Delia Leticia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química, Física de los Materiales, Medioambiente y Energía. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química, Física de los Materiales, Medioambiente y Energía; ArgentinaBentham Sci. Pub.2010-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/71754Fernandez, Marcelo Raul; Bernik, Delia Leticia; Whole-cell biosensors: research and patents; Bentham Sci. Pub.; Recent Patents on Biomedical Engineering; 3; 3; 7-2010; 138-1462211-31201874-7647CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.ingentaconnect.com/content/ben/biomeng/2010/00000003/00000003/art00003info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:46:57Zoai:ri.conicet.gov.ar:11336/71754instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:46:57.756CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Whole-cell biosensors: research and patents
title Whole-cell biosensors: research and patents
spellingShingle Whole-cell biosensors: research and patents
Fernandez, Marcelo Raul
Bioreporters
Whole-Cell Biosensors
Living Sensors
Integrated Sensors
title_short Whole-cell biosensors: research and patents
title_full Whole-cell biosensors: research and patents
title_fullStr Whole-cell biosensors: research and patents
title_full_unstemmed Whole-cell biosensors: research and patents
title_sort Whole-cell biosensors: research and patents
dc.creator.none.fl_str_mv Fernandez, Marcelo Raul
Bernik, Delia Leticia
author Fernandez, Marcelo Raul
author_facet Fernandez, Marcelo Raul
Bernik, Delia Leticia
author_role author
author2 Bernik, Delia Leticia
author2_role author
dc.subject.none.fl_str_mv Bioreporters
Whole-Cell Biosensors
Living Sensors
Integrated Sensors
topic Bioreporters
Whole-Cell Biosensors
Living Sensors
Integrated Sensors
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.8
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv In the last ten years several research articles and patents related to the obtaining and uses of whole-cell biosen- sors (WCB) have been published. Whole-cell sensors, whole-cell biosensors, chemical sensors, integrated sensors and bioreporters (among others) are the main terms used to define a living cell machinery adapted to detect target analytes at low concentration levels. The methods for constructing and detection technologies for these WCB could be very diverse. Some of them include a foreign nucleic acid sequence to act as reporter, to regulate the reporter’s expression or both. But some other inventors ex- ploit the natural properties of organisms without the need of genetic engineering. Another aspect is the localization of the cell at the moment of use. Some inventors, depending on the method of detection, need cells in a special location, such as the surface of a detector, entrapped in a matrix, or in the bulk of the sample. This review intends to compile the most rele- vant patents related to WCB which enable to illustrate the above mentioned cases of these new types of biosensors.
Fil: Fernandez, Marcelo Raul. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química, Física de los Materiales, Medioambiente y Energía. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química, Física de los Materiales, Medioambiente y Energía; Argentina
Fil: Bernik, Delia Leticia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química, Física de los Materiales, Medioambiente y Energía. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química, Física de los Materiales, Medioambiente y Energía; Argentina
description In the last ten years several research articles and patents related to the obtaining and uses of whole-cell biosen- sors (WCB) have been published. Whole-cell sensors, whole-cell biosensors, chemical sensors, integrated sensors and bioreporters (among others) are the main terms used to define a living cell machinery adapted to detect target analytes at low concentration levels. The methods for constructing and detection technologies for these WCB could be very diverse. Some of them include a foreign nucleic acid sequence to act as reporter, to regulate the reporter’s expression or both. But some other inventors ex- ploit the natural properties of organisms without the need of genetic engineering. Another aspect is the localization of the cell at the moment of use. Some inventors, depending on the method of detection, need cells in a special location, such as the surface of a detector, entrapped in a matrix, or in the bulk of the sample. This review intends to compile the most rele- vant patents related to WCB which enable to illustrate the above mentioned cases of these new types of biosensors.
publishDate 2010
dc.date.none.fl_str_mv 2010-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/71754
Fernandez, Marcelo Raul; Bernik, Delia Leticia; Whole-cell biosensors: research and patents; Bentham Sci. Pub.; Recent Patents on Biomedical Engineering; 3; 3; 7-2010; 138-146
2211-3120
1874-7647
CONICET Digital
CONICET
url http://hdl.handle.net/11336/71754
identifier_str_mv Fernandez, Marcelo Raul; Bernik, Delia Leticia; Whole-cell biosensors: research and patents; Bentham Sci. Pub.; Recent Patents on Biomedical Engineering; 3; 3; 7-2010; 138-146
2211-3120
1874-7647
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.ingentaconnect.com/content/ben/biomeng/2010/00000003/00000003/art00003
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Bentham Sci. Pub.
publisher.none.fl_str_mv Bentham Sci. Pub.
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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