Is the vertebral canal prepared to host the aged spinal cord? A morphometric assessment

Autores
Nishida, Fabian; Barbeito Andrés, Jimena; Barbeito, Claudio Gustavo; Portiansky, Enrique Leo
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Although the interaction between the growing spinal cord and the vertebrae has been widely demonstrated for mammal’s prenatal and early postnatal life, there is no extensive knowledge about this interaction during late postnatal stages. It has been shown that spinal cord injuries are causally related to significant degenerative changes in bone properties. Nevertheless, information about a possible influence of the spinal cord on bone remodelling in adult healthy animals is missing. The aim of this research work was to assess possible morphological changes of the cervical vertebral canal of juvenile and aged rats during the ontogenetic period of adulthood that would justify the suggested influence. Since the spinal cord of rats increases its size with ageing, we analysed whether morphometric changes are occurring in the vertebral canal that would indicate bone remodelling in response to said growth. To this end, we used three complementary morphometric methods to describe the canal of the cervical and the first thoracic vertebrae. Geometric morphometric analyses evidence scarce variation in size and shape between juvenile and aged rats suggesting that, in general terms, the canal morphology of cervical vertebrae is already prepared in early adulthood to host the growing spinal cord. C3 was the only vertebra that showed consistent variation for the variables of canal thickness, perimeter, height and area. This regional variation may be linked to the patterns described for the changing spinal cord.
Fil: Nishida, Fabian. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
Fil: Barbeito Andrés, Jimena. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
Fil: Barbeito, Claudio Gustavo. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
Fil: Portiansky, Enrique Leo. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
Materia
AGEING
MORPHOMETRY
RAT
REMODELLING
VERTEBRA
VERTEBRAL CANAL
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/31420
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Is the vertebral canal prepared to host the aged spinal cord? A morphometric assessmentNishida, FabianBarbeito Andrés, JimenaBarbeito, Claudio GustavoPortiansky, Enrique LeoAGEINGMORPHOMETRYRATREMODELLINGVERTEBRAVERTEBRAL CANALhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Although the interaction between the growing spinal cord and the vertebrae has been widely demonstrated for mammal’s prenatal and early postnatal life, there is no extensive knowledge about this interaction during late postnatal stages. It has been shown that spinal cord injuries are causally related to significant degenerative changes in bone properties. Nevertheless, information about a possible influence of the spinal cord on bone remodelling in adult healthy animals is missing. The aim of this research work was to assess possible morphological changes of the cervical vertebral canal of juvenile and aged rats during the ontogenetic period of adulthood that would justify the suggested influence. Since the spinal cord of rats increases its size with ageing, we analysed whether morphometric changes are occurring in the vertebral canal that would indicate bone remodelling in response to said growth. To this end, we used three complementary morphometric methods to describe the canal of the cervical and the first thoracic vertebrae. Geometric morphometric analyses evidence scarce variation in size and shape between juvenile and aged rats suggesting that, in general terms, the canal morphology of cervical vertebrae is already prepared in early adulthood to host the growing spinal cord. C3 was the only vertebra that showed consistent variation for the variables of canal thickness, perimeter, height and area. This regional variation may be linked to the patterns described for the changing spinal cord.Fil: Nishida, Fabian. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Barbeito Andrés, Jimena. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Barbeito, Claudio Gustavo. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Portiansky, Enrique Leo. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaSpringer2014-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/31420Nishida, Fabian; Barbeito Andrés, Jimena; Barbeito, Claudio Gustavo; Portiansky, Enrique Leo; Is the vertebral canal prepared to host the aged spinal cord? A morphometric assessment; Springer; Zoomorphology (Berlin. Print); 133; 2; 1-2014; 219-2250720-213X1432-234XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1007/s00435-013-0215-2info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs00435-013-0215-2info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:53:46Zoai:ri.conicet.gov.ar:11336/31420instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:53:46.43CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Is the vertebral canal prepared to host the aged spinal cord? A morphometric assessment
title Is the vertebral canal prepared to host the aged spinal cord? A morphometric assessment
spellingShingle Is the vertebral canal prepared to host the aged spinal cord? A morphometric assessment
Nishida, Fabian
AGEING
MORPHOMETRY
RAT
REMODELLING
VERTEBRA
VERTEBRAL CANAL
title_short Is the vertebral canal prepared to host the aged spinal cord? A morphometric assessment
title_full Is the vertebral canal prepared to host the aged spinal cord? A morphometric assessment
title_fullStr Is the vertebral canal prepared to host the aged spinal cord? A morphometric assessment
title_full_unstemmed Is the vertebral canal prepared to host the aged spinal cord? A morphometric assessment
title_sort Is the vertebral canal prepared to host the aged spinal cord? A morphometric assessment
dc.creator.none.fl_str_mv Nishida, Fabian
Barbeito Andrés, Jimena
Barbeito, Claudio Gustavo
Portiansky, Enrique Leo
author Nishida, Fabian
author_facet Nishida, Fabian
Barbeito Andrés, Jimena
Barbeito, Claudio Gustavo
Portiansky, Enrique Leo
author_role author
author2 Barbeito Andrés, Jimena
Barbeito, Claudio Gustavo
Portiansky, Enrique Leo
author2_role author
author
author
dc.subject.none.fl_str_mv AGEING
MORPHOMETRY
RAT
REMODELLING
VERTEBRA
VERTEBRAL CANAL
topic AGEING
MORPHOMETRY
RAT
REMODELLING
VERTEBRA
VERTEBRAL CANAL
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Although the interaction between the growing spinal cord and the vertebrae has been widely demonstrated for mammal’s prenatal and early postnatal life, there is no extensive knowledge about this interaction during late postnatal stages. It has been shown that spinal cord injuries are causally related to significant degenerative changes in bone properties. Nevertheless, information about a possible influence of the spinal cord on bone remodelling in adult healthy animals is missing. The aim of this research work was to assess possible morphological changes of the cervical vertebral canal of juvenile and aged rats during the ontogenetic period of adulthood that would justify the suggested influence. Since the spinal cord of rats increases its size with ageing, we analysed whether morphometric changes are occurring in the vertebral canal that would indicate bone remodelling in response to said growth. To this end, we used three complementary morphometric methods to describe the canal of the cervical and the first thoracic vertebrae. Geometric morphometric analyses evidence scarce variation in size and shape between juvenile and aged rats suggesting that, in general terms, the canal morphology of cervical vertebrae is already prepared in early adulthood to host the growing spinal cord. C3 was the only vertebra that showed consistent variation for the variables of canal thickness, perimeter, height and area. This regional variation may be linked to the patterns described for the changing spinal cord.
Fil: Nishida, Fabian. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
Fil: Barbeito Andrés, Jimena. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
Fil: Barbeito, Claudio Gustavo. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
Fil: Portiansky, Enrique Leo. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
description Although the interaction between the growing spinal cord and the vertebrae has been widely demonstrated for mammal’s prenatal and early postnatal life, there is no extensive knowledge about this interaction during late postnatal stages. It has been shown that spinal cord injuries are causally related to significant degenerative changes in bone properties. Nevertheless, information about a possible influence of the spinal cord on bone remodelling in adult healthy animals is missing. The aim of this research work was to assess possible morphological changes of the cervical vertebral canal of juvenile and aged rats during the ontogenetic period of adulthood that would justify the suggested influence. Since the spinal cord of rats increases its size with ageing, we analysed whether morphometric changes are occurring in the vertebral canal that would indicate bone remodelling in response to said growth. To this end, we used three complementary morphometric methods to describe the canal of the cervical and the first thoracic vertebrae. Geometric morphometric analyses evidence scarce variation in size and shape between juvenile and aged rats suggesting that, in general terms, the canal morphology of cervical vertebrae is already prepared in early adulthood to host the growing spinal cord. C3 was the only vertebra that showed consistent variation for the variables of canal thickness, perimeter, height and area. This regional variation may be linked to the patterns described for the changing spinal cord.
publishDate 2014
dc.date.none.fl_str_mv 2014-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/31420
Nishida, Fabian; Barbeito Andrés, Jimena; Barbeito, Claudio Gustavo; Portiansky, Enrique Leo; Is the vertebral canal prepared to host the aged spinal cord? A morphometric assessment; Springer; Zoomorphology (Berlin. Print); 133; 2; 1-2014; 219-225
0720-213X
1432-234X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/31420
identifier_str_mv Nishida, Fabian; Barbeito Andrés, Jimena; Barbeito, Claudio Gustavo; Portiansky, Enrique Leo; Is the vertebral canal prepared to host the aged spinal cord? A morphometric assessment; Springer; Zoomorphology (Berlin. Print); 133; 2; 1-2014; 219-225
0720-213X
1432-234X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1007/s00435-013-0215-2
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs00435-013-0215-2
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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