Conditioned inhibition in preweanling rats

Autores
Aranda-Fernandez, Patricio E.; Gaztañaga, Mirari; Arias Grandio, Carlos; Chotro, M. Gabriela
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Inhibitory conditioning is a very well established phenomenon in associative learning that has been demonstrated in both humans and adult animals. But in spite of the fact that this topic has generated much empirical and theoretical work, there are no published studies assessing inhibitory learning during the early ontogeny of the rat. In this study we test the possibility of finding conditioned inhibition in infant rats (Day 10) using a conditioned taste aversion procedure. We tested whether the consumption of saccharin (A) was reduced when paired with a LiCl injection compared to the presentation of saccharin in compound with a lemon odor (AX) without any aversive consequence. After training, retardation, and summation tests were conducted in order to evaluate the inhibitory properties of the lemon odor (X). The results of this study showed that in male pups, after conditioned inhibition training, stimulus X passed both retardation and summation tests. These results indicate that conditioned inhibition can be established in the early development of the rat, suggesting that animals at this stage of ontogeny have the capacity to acquire and to express inhibitory conditioning, although this effect appears to be sex-dependent.
Fil: Aranda-Fernandez, Patricio E.. Universidad del País Vasco; España
Fil: Gaztañaga, Mirari. Universidad del País Vasco; España
Fil: Arias Grandio, Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Universidad del País Vasco; España
Fil: Chotro, M. Gabriela. Universidad del País Vasco; España
Materia
Conditioned Inhibition
Conditioned Taste Aversion
Preweanling
Rat
Sex Differences
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/69321
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Conditioned inhibition in preweanling ratsAranda-Fernandez, Patricio E.Gaztañaga, MirariArias Grandio, CarlosChotro, M. GabrielaConditioned InhibitionConditioned Taste AversionPreweanlingRatSex Differenceshttps://purl.org/becyt/ford/5.1https://purl.org/becyt/ford/5Inhibitory conditioning is a very well established phenomenon in associative learning that has been demonstrated in both humans and adult animals. But in spite of the fact that this topic has generated much empirical and theoretical work, there are no published studies assessing inhibitory learning during the early ontogeny of the rat. In this study we test the possibility of finding conditioned inhibition in infant rats (Day 10) using a conditioned taste aversion procedure. We tested whether the consumption of saccharin (A) was reduced when paired with a LiCl injection compared to the presentation of saccharin in compound with a lemon odor (AX) without any aversive consequence. After training, retardation, and summation tests were conducted in order to evaluate the inhibitory properties of the lemon odor (X). The results of this study showed that in male pups, after conditioned inhibition training, stimulus X passed both retardation and summation tests. These results indicate that conditioned inhibition can be established in the early development of the rat, suggesting that animals at this stage of ontogeny have the capacity to acquire and to express inhibitory conditioning, although this effect appears to be sex-dependent.Fil: Aranda-Fernandez, Patricio E.. Universidad del País Vasco; EspañaFil: Gaztañaga, Mirari. Universidad del País Vasco; EspañaFil: Arias Grandio, Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Universidad del País Vasco; EspañaFil: Chotro, M. Gabriela. Universidad del País Vasco; EspañaJohn Wiley & Sons Inc2016-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/69321Aranda-Fernandez, Patricio E.; Gaztañaga, Mirari; Arias Grandio, Carlos; Chotro, M. Gabriela; Conditioned inhibition in preweanling rats; John Wiley & Sons Inc; Developmental Psychobiology; 58; 1; 1-2016; 98-1060012-1630CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1002/dev.21359info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1002/dev.21359info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:05:15Zoai:ri.conicet.gov.ar:11336/69321instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:05:15.831CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Conditioned inhibition in preweanling rats
title Conditioned inhibition in preweanling rats
spellingShingle Conditioned inhibition in preweanling rats
Aranda-Fernandez, Patricio E.
Conditioned Inhibition
Conditioned Taste Aversion
Preweanling
Rat
Sex Differences
title_short Conditioned inhibition in preweanling rats
title_full Conditioned inhibition in preweanling rats
title_fullStr Conditioned inhibition in preweanling rats
title_full_unstemmed Conditioned inhibition in preweanling rats
title_sort Conditioned inhibition in preweanling rats
dc.creator.none.fl_str_mv Aranda-Fernandez, Patricio E.
Gaztañaga, Mirari
Arias Grandio, Carlos
Chotro, M. Gabriela
author Aranda-Fernandez, Patricio E.
author_facet Aranda-Fernandez, Patricio E.
Gaztañaga, Mirari
Arias Grandio, Carlos
Chotro, M. Gabriela
author_role author
author2 Gaztañaga, Mirari
Arias Grandio, Carlos
Chotro, M. Gabriela
author2_role author
author
author
dc.subject.none.fl_str_mv Conditioned Inhibition
Conditioned Taste Aversion
Preweanling
Rat
Sex Differences
topic Conditioned Inhibition
Conditioned Taste Aversion
Preweanling
Rat
Sex Differences
purl_subject.fl_str_mv https://purl.org/becyt/ford/5.1
https://purl.org/becyt/ford/5
dc.description.none.fl_txt_mv Inhibitory conditioning is a very well established phenomenon in associative learning that has been demonstrated in both humans and adult animals. But in spite of the fact that this topic has generated much empirical and theoretical work, there are no published studies assessing inhibitory learning during the early ontogeny of the rat. In this study we test the possibility of finding conditioned inhibition in infant rats (Day 10) using a conditioned taste aversion procedure. We tested whether the consumption of saccharin (A) was reduced when paired with a LiCl injection compared to the presentation of saccharin in compound with a lemon odor (AX) without any aversive consequence. After training, retardation, and summation tests were conducted in order to evaluate the inhibitory properties of the lemon odor (X). The results of this study showed that in male pups, after conditioned inhibition training, stimulus X passed both retardation and summation tests. These results indicate that conditioned inhibition can be established in the early development of the rat, suggesting that animals at this stage of ontogeny have the capacity to acquire and to express inhibitory conditioning, although this effect appears to be sex-dependent.
Fil: Aranda-Fernandez, Patricio E.. Universidad del País Vasco; España
Fil: Gaztañaga, Mirari. Universidad del País Vasco; España
Fil: Arias Grandio, Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Universidad del País Vasco; España
Fil: Chotro, M. Gabriela. Universidad del País Vasco; España
description Inhibitory conditioning is a very well established phenomenon in associative learning that has been demonstrated in both humans and adult animals. But in spite of the fact that this topic has generated much empirical and theoretical work, there are no published studies assessing inhibitory learning during the early ontogeny of the rat. In this study we test the possibility of finding conditioned inhibition in infant rats (Day 10) using a conditioned taste aversion procedure. We tested whether the consumption of saccharin (A) was reduced when paired with a LiCl injection compared to the presentation of saccharin in compound with a lemon odor (AX) without any aversive consequence. After training, retardation, and summation tests were conducted in order to evaluate the inhibitory properties of the lemon odor (X). The results of this study showed that in male pups, after conditioned inhibition training, stimulus X passed both retardation and summation tests. These results indicate that conditioned inhibition can be established in the early development of the rat, suggesting that animals at this stage of ontogeny have the capacity to acquire and to express inhibitory conditioning, although this effect appears to be sex-dependent.
publishDate 2016
dc.date.none.fl_str_mv 2016-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/69321
Aranda-Fernandez, Patricio E.; Gaztañaga, Mirari; Arias Grandio, Carlos; Chotro, M. Gabriela; Conditioned inhibition in preweanling rats; John Wiley & Sons Inc; Developmental Psychobiology; 58; 1; 1-2016; 98-106
0012-1630
CONICET Digital
CONICET
url http://hdl.handle.net/11336/69321
identifier_str_mv Aranda-Fernandez, Patricio E.; Gaztañaga, Mirari; Arias Grandio, Carlos; Chotro, M. Gabriela; Conditioned inhibition in preweanling rats; John Wiley & Sons Inc; Developmental Psychobiology; 58; 1; 1-2016; 98-106
0012-1630
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1002/dev.21359
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1002/dev.21359
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv John Wiley & Sons Inc
publisher.none.fl_str_mv John Wiley & Sons Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.993085

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