Reacquisition, reinstatement, and renewal of a conditioned taste aversion in preweanling rats

Autores
Revillo, Damian Alejandro; Castelló, Stefanía Anabel; Paglini, Maria Gabriela; Arias, C.
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Pavlovian extinction is defined as a reduction of the conditioned response (CR) as a consequence of repeated and nonreinforced presentations of the conditioned stimulus (CS). This phenomenon has been explained through two nonexclusive associative hypotheses. One of them proposes that the CS– unconditioned stimulus (US) association is weakened during extinction, while the second one explains extinction by the formation of a new inhibitory association between the CS, and the US (CS–noUS) which competes with the excitatory one acquired at conditioning (CS–US). Research supporting this second hypothesis is based on the demonstration that the CR can be recovered after extinction. However, in preweanling rats, renewal, and reinstatement treatments have failed to recover a conditioned fear response, suggesting that extinction during this ontogenetic period may involve erasure of the CS–US association. The goal of the present study was to explore whether this conclusion can be extended to the extinction of a conditioned taste aversion by evaluating infant rats in three different procedures (reacquisition, ABA renewal, and reinstatement). The results are consistent with the idea that extinction of a taste aversive memory during infancy involves relearning about the relationship between the CS and the US, with the initial CS–US association remaining relatively intact. Extinction of a taste aversive memory and a fear memory may involve different biological mechanisms during infancy. The conclusion that the only psychological mechanism for extinction during infancy is unlearning should be confined to a particular type of memory.
Fil: Revillo, Damian Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
Fil: Castelló, Stefanía Anabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
Fil: Paglini, Maria Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
Fil: Arias, C.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
Materia
Extinction
Infant
Rat
Taste Aversion
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/25707
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/25707
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Reacquisition, reinstatement, and renewal of a conditioned taste aversion in preweanling ratsRevillo, Damian AlejandroCastelló, Stefanía AnabelPaglini, Maria GabrielaArias, C.ExtinctionInfantRatTaste Aversionhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Pavlovian extinction is defined as a reduction of the conditioned response (CR) as a consequence of repeated and nonreinforced presentations of the conditioned stimulus (CS). This phenomenon has been explained through two nonexclusive associative hypotheses. One of them proposes that the CS– unconditioned stimulus (US) association is weakened during extinction, while the second one explains extinction by the formation of a new inhibitory association between the CS, and the US (CS–noUS) which competes with the excitatory one acquired at conditioning (CS–US). Research supporting this second hypothesis is based on the demonstration that the CR can be recovered after extinction. However, in preweanling rats, renewal, and reinstatement treatments have failed to recover a conditioned fear response, suggesting that extinction during this ontogenetic period may involve erasure of the CS–US association. The goal of the present study was to explore whether this conclusion can be extended to the extinction of a conditioned taste aversion by evaluating infant rats in three different procedures (reacquisition, ABA renewal, and reinstatement). The results are consistent with the idea that extinction of a taste aversive memory during infancy involves relearning about the relationship between the CS and the US, with the initial CS–US association remaining relatively intact. Extinction of a taste aversive memory and a fear memory may involve different biological mechanisms during infancy. The conclusion that the only psychological mechanism for extinction during infancy is unlearning should be confined to a particular type of memory.Fil: Revillo, Damian Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; ArgentinaFil: Castelló, Stefanía Anabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; ArgentinaFil: Paglini, Maria Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; ArgentinaFil: Arias, C.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; ArgentinaWiley2013-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/25707Revillo, Damian Alejandro; Castelló, Stefanía Anabel; Paglini, Maria Gabriela; Arias, C.; Reacquisition, reinstatement, and renewal of a conditioned taste aversion in preweanling rats; Wiley; Developmental Psychobiology; 56; 4; 6-2013; 713-7250012-1630CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1002/dev.21140info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/dev.21140/abstractinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:41:25Zoai:ri.conicet.gov.ar:11336/25707instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:41:25.648CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Reacquisition, reinstatement, and renewal of a conditioned taste aversion in preweanling rats
title Reacquisition, reinstatement, and renewal of a conditioned taste aversion in preweanling rats
spellingShingle Reacquisition, reinstatement, and renewal of a conditioned taste aversion in preweanling rats
Revillo, Damian Alejandro
Extinction
Infant
Rat
Taste Aversion
title_short Reacquisition, reinstatement, and renewal of a conditioned taste aversion in preweanling rats
title_full Reacquisition, reinstatement, and renewal of a conditioned taste aversion in preweanling rats
title_fullStr Reacquisition, reinstatement, and renewal of a conditioned taste aversion in preweanling rats
title_full_unstemmed Reacquisition, reinstatement, and renewal of a conditioned taste aversion in preweanling rats
title_sort Reacquisition, reinstatement, and renewal of a conditioned taste aversion in preweanling rats
dc.creator.none.fl_str_mv Revillo, Damian Alejandro
Castelló, Stefanía Anabel
Paglini, Maria Gabriela
Arias, C.
author Revillo, Damian Alejandro
author_facet Revillo, Damian Alejandro
Castelló, Stefanía Anabel
Paglini, Maria Gabriela
Arias, C.
author_role author
author2 Castelló, Stefanía Anabel
Paglini, Maria Gabriela
Arias, C.
author2_role author
author
author
dc.subject.none.fl_str_mv Extinction
Infant
Rat
Taste Aversion
topic Extinction
Infant
Rat
Taste Aversion
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Pavlovian extinction is defined as a reduction of the conditioned response (CR) as a consequence of repeated and nonreinforced presentations of the conditioned stimulus (CS). This phenomenon has been explained through two nonexclusive associative hypotheses. One of them proposes that the CS– unconditioned stimulus (US) association is weakened during extinction, while the second one explains extinction by the formation of a new inhibitory association between the CS, and the US (CS–noUS) which competes with the excitatory one acquired at conditioning (CS–US). Research supporting this second hypothesis is based on the demonstration that the CR can be recovered after extinction. However, in preweanling rats, renewal, and reinstatement treatments have failed to recover a conditioned fear response, suggesting that extinction during this ontogenetic period may involve erasure of the CS–US association. The goal of the present study was to explore whether this conclusion can be extended to the extinction of a conditioned taste aversion by evaluating infant rats in three different procedures (reacquisition, ABA renewal, and reinstatement). The results are consistent with the idea that extinction of a taste aversive memory during infancy involves relearning about the relationship between the CS and the US, with the initial CS–US association remaining relatively intact. Extinction of a taste aversive memory and a fear memory may involve different biological mechanisms during infancy. The conclusion that the only psychological mechanism for extinction during infancy is unlearning should be confined to a particular type of memory.
Fil: Revillo, Damian Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
Fil: Castelló, Stefanía Anabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
Fil: Paglini, Maria Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
Fil: Arias, C.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
description Pavlovian extinction is defined as a reduction of the conditioned response (CR) as a consequence of repeated and nonreinforced presentations of the conditioned stimulus (CS). This phenomenon has been explained through two nonexclusive associative hypotheses. One of them proposes that the CS– unconditioned stimulus (US) association is weakened during extinction, while the second one explains extinction by the formation of a new inhibitory association between the CS, and the US (CS–noUS) which competes with the excitatory one acquired at conditioning (CS–US). Research supporting this second hypothesis is based on the demonstration that the CR can be recovered after extinction. However, in preweanling rats, renewal, and reinstatement treatments have failed to recover a conditioned fear response, suggesting that extinction during this ontogenetic period may involve erasure of the CS–US association. The goal of the present study was to explore whether this conclusion can be extended to the extinction of a conditioned taste aversion by evaluating infant rats in three different procedures (reacquisition, ABA renewal, and reinstatement). The results are consistent with the idea that extinction of a taste aversive memory during infancy involves relearning about the relationship between the CS and the US, with the initial CS–US association remaining relatively intact. Extinction of a taste aversive memory and a fear memory may involve different biological mechanisms during infancy. The conclusion that the only psychological mechanism for extinction during infancy is unlearning should be confined to a particular type of memory.
publishDate 2013
dc.date.none.fl_str_mv 2013-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/25707
Revillo, Damian Alejandro; Castelló, Stefanía Anabel; Paglini, Maria Gabriela; Arias, C.; Reacquisition, reinstatement, and renewal of a conditioned taste aversion in preweanling rats; Wiley; Developmental Psychobiology; 56; 4; 6-2013; 713-725
0012-1630
CONICET Digital
CONICET
url http://hdl.handle.net/11336/25707
identifier_str_mv Revillo, Damian Alejandro; Castelló, Stefanía Anabel; Paglini, Maria Gabriela; Arias, C.; Reacquisition, reinstatement, and renewal of a conditioned taste aversion in preweanling rats; Wiley; Developmental Psychobiology; 56; 4; 6-2013; 713-725
0012-1630
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1002/dev.21140
info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/dev.21140/abstract
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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