Identification of human sperm proteins involved in the interaction with homologous zona pellucida

Autores
Lasserre, Andrea; Gonzalez Echeverria, Fernanda; Moules, Carolina; Tezon, Jorge Guillermo; Miranda, Patricia Vivian; Vazquez, Monica Hebe
Año de publicación
2003
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
To identify human sperm proteins involved in homologous zona pellucida (ZP) interaction.Fertilization results from successful interaction between the female and male gametes. Capacitated human spermatozoa initially bind, in a species-specific manner, with the zona pellucida (ZP), an extracellular coat that surrounds all mammalian eggs. As a result of this interaction, spermatozoa undergo an exocytotic process called the acrosome reaction, which allows sperm penetration through the ZP and fusion with the oocyte plasma membrane (1, 2). In many mammals, including humans, it has been shown that the ZP is composed of three glycoproteins, called ZP1, ZP2, and ZP3, which are well characterized at biochemical and molecular level (3, 4). Of the three components, ZP3 is responsible for primary sperm binding to the ZP and induction of the acrosome reaction (AR) (5, 6), while ZP2 would participate in secondary binding to the ZP (7).
Fil: Lasserre, Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Gonzalez Echeverria, Fernanda. Fertilab; Argentina
Fil: Moules, Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Tezon, Jorge Guillermo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Miranda, Patricia Vivian. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Vazquez, Monica Hebe. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Materia
Sperm
Zona Pellucida
Fertilization
Antibodies
Epididymis
Sperm-Egg Interaction
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/36411
Acceder
id CONICETDig_ea288b8815e7e2cf799c1d82656cab65
oai_identifier_str oai:ri.conicet.gov.ar:11336/36411
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Identification of human sperm proteins involved in the interaction with homologous zona pellucidaLasserre, AndreaGonzalez Echeverria, FernandaMoules, CarolinaTezon, Jorge GuillermoMiranda, Patricia VivianVazquez, Monica HebeSpermZona PellucidaFertilizationAntibodiesEpididymisSperm-Egg Interactionhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1https://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3To identify human sperm proteins involved in homologous zona pellucida (ZP) interaction.Fertilization results from successful interaction between the female and male gametes. Capacitated human spermatozoa initially bind, in a species-specific manner, with the zona pellucida (ZP), an extracellular coat that surrounds all mammalian eggs. As a result of this interaction, spermatozoa undergo an exocytotic process called the acrosome reaction, which allows sperm penetration through the ZP and fusion with the oocyte plasma membrane (1, 2). In many mammals, including humans, it has been shown that the ZP is composed of three glycoproteins, called ZP1, ZP2, and ZP3, which are well characterized at biochemical and molecular level (3, 4). Of the three components, ZP3 is responsible for primary sperm binding to the ZP and induction of the acrosome reaction (AR) (5, 6), while ZP2 would participate in secondary binding to the ZP (7).Fil: Lasserre, Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Gonzalez Echeverria, Fernanda. Fertilab; ArgentinaFil: Moules, Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Tezon, Jorge Guillermo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Miranda, Patricia Vivian. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Vazquez, Monica Hebe. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaAmerican Society for Reproductive Medicine2003-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/36411Lasserre, Andrea; Gonzalez Echeverria, Fernanda; Moules, Carolina; Tezon, Jorge Guillermo; Miranda, Patricia Vivian; et al.; Identification of human sperm proteins involved in the interaction with homologous zona pellucida; American Society for Reproductive Medicine; Fertility and Sterility; 79; 3; 6-2003; 1606-16150015-0282CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.fertstert.org/article/S0015-0282(03)00251-6/abstractinfo:eu-repo/semantics/altIdentifier/doi/10.1016/S0015-0282(03)00251-6info:eu-repo/semantics/altIdentifier/pmid/12801567info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T12:16:14Zoai:ri.conicet.gov.ar:11336/36411instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 12:16:14.609CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Identification of human sperm proteins involved in the interaction with homologous zona pellucida
title Identification of human sperm proteins involved in the interaction with homologous zona pellucida
spellingShingle Identification of human sperm proteins involved in the interaction with homologous zona pellucida
Lasserre, Andrea
Sperm
Zona Pellucida
Fertilization
Antibodies
Epididymis
Sperm-Egg Interaction
title_short Identification of human sperm proteins involved in the interaction with homologous zona pellucida
title_full Identification of human sperm proteins involved in the interaction with homologous zona pellucida
title_fullStr Identification of human sperm proteins involved in the interaction with homologous zona pellucida
title_full_unstemmed Identification of human sperm proteins involved in the interaction with homologous zona pellucida
title_sort Identification of human sperm proteins involved in the interaction with homologous zona pellucida
dc.creator.none.fl_str_mv Lasserre, Andrea
Gonzalez Echeverria, Fernanda
Moules, Carolina
Tezon, Jorge Guillermo
Miranda, Patricia Vivian
Vazquez, Monica Hebe
author Lasserre, Andrea
author_facet Lasserre, Andrea
Gonzalez Echeverria, Fernanda
Moules, Carolina
Tezon, Jorge Guillermo
Miranda, Patricia Vivian
Vazquez, Monica Hebe
author_role author
author2 Gonzalez Echeverria, Fernanda
Moules, Carolina
Tezon, Jorge Guillermo
Miranda, Patricia Vivian
Vazquez, Monica Hebe
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Sperm
Zona Pellucida
Fertilization
Antibodies
Epididymis
Sperm-Egg Interaction
topic Sperm
Zona Pellucida
Fertilization
Antibodies
Epididymis
Sperm-Egg Interaction
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv To identify human sperm proteins involved in homologous zona pellucida (ZP) interaction.Fertilization results from successful interaction between the female and male gametes. Capacitated human spermatozoa initially bind, in a species-specific manner, with the zona pellucida (ZP), an extracellular coat that surrounds all mammalian eggs. As a result of this interaction, spermatozoa undergo an exocytotic process called the acrosome reaction, which allows sperm penetration through the ZP and fusion with the oocyte plasma membrane (1, 2). In many mammals, including humans, it has been shown that the ZP is composed of three glycoproteins, called ZP1, ZP2, and ZP3, which are well characterized at biochemical and molecular level (3, 4). Of the three components, ZP3 is responsible for primary sperm binding to the ZP and induction of the acrosome reaction (AR) (5, 6), while ZP2 would participate in secondary binding to the ZP (7).
Fil: Lasserre, Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Gonzalez Echeverria, Fernanda. Fertilab; Argentina
Fil: Moules, Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Tezon, Jorge Guillermo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Miranda, Patricia Vivian. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Vazquez, Monica Hebe. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
description To identify human sperm proteins involved in homologous zona pellucida (ZP) interaction.Fertilization results from successful interaction between the female and male gametes. Capacitated human spermatozoa initially bind, in a species-specific manner, with the zona pellucida (ZP), an extracellular coat that surrounds all mammalian eggs. As a result of this interaction, spermatozoa undergo an exocytotic process called the acrosome reaction, which allows sperm penetration through the ZP and fusion with the oocyte plasma membrane (1, 2). In many mammals, including humans, it has been shown that the ZP is composed of three glycoproteins, called ZP1, ZP2, and ZP3, which are well characterized at biochemical and molecular level (3, 4). Of the three components, ZP3 is responsible for primary sperm binding to the ZP and induction of the acrosome reaction (AR) (5, 6), while ZP2 would participate in secondary binding to the ZP (7).
publishDate 2003
dc.date.none.fl_str_mv 2003-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/36411
Lasserre, Andrea; Gonzalez Echeverria, Fernanda; Moules, Carolina; Tezon, Jorge Guillermo; Miranda, Patricia Vivian; et al.; Identification of human sperm proteins involved in the interaction with homologous zona pellucida; American Society for Reproductive Medicine; Fertility and Sterility; 79; 3; 6-2003; 1606-1615
0015-0282
CONICET Digital
CONICET
url http://hdl.handle.net/11336/36411
identifier_str_mv Lasserre, Andrea; Gonzalez Echeverria, Fernanda; Moules, Carolina; Tezon, Jorge Guillermo; Miranda, Patricia Vivian; et al.; Identification of human sperm proteins involved in the interaction with homologous zona pellucida; American Society for Reproductive Medicine; Fertility and Sterility; 79; 3; 6-2003; 1606-1615
0015-0282
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.fertstert.org/article/S0015-0282(03)00251-6/abstract
info:eu-repo/semantics/altIdentifier/doi/10.1016/S0015-0282(03)00251-6
info:eu-repo/semantics/altIdentifier/pmid/12801567
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Society for Reproductive Medicine
publisher.none.fl_str_mv American Society for Reproductive Medicine
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846782581677228032
score 13.120347

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