COVID-19 pandemic and vitamin D deficiency: a different approach with an analysis of the findings and a complimentary proposal

Autores
Martín Giménez, Virna Margarita; Bergam, Ivana; Inserra, Felipe; Ferder, Leon Fernando; Reiter, Russel; Manucha, Walter Ariel Fernando
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Vitamin D is an essential immune-modulator with receptors widely distributed throughout the body, and its serum levels fluctuate significantly among individuals between winter and summer months (from 30 to 50%). This study examines the association between low vitamin D status and prevalence of COVID-19 cases around the world and proposes a relationship between the seasonal character of the human immune system strength rather than to the seasonal infectivity of viruses. Also, this review suggests the observed geographical disparities in COVID-19 infections were due to differences in vitamin D levels. On the international scale, serum vitamin D levels are reportedly lowest in China, the Middle East, and South Europe; these populations also had the largest outbreaks of COVID-19 cases. In addition to the geographical differences in vitamin D status, there are known risk groups (ethnic, age-related, pregnancies). On the contrary, some countries including Canada, Finland, and North Europe incorporate increased amounts of vitamin D through fortified foods, vitamin D supplements, and sunbathing. These countries show the lowest morbidity and mortality rates by COVID-19 infection and demonstrate that lower ambient temperatures do not contribute to a higher number of COVID-19 cases. COVID-19 has spread around the globe almost simultaneously in both warm and cold areas. Given this information, vitamin D measurement should become an essential component of public health monitoring as a biomarker of immunity status. Clinical trials should be conducted to confirm this hypothesis. COVID-19 tests should be performed together with vitamin D status tests to verify this proposed relationship.
Fil: Martín Giménez, Virna Margarita. Universidad Catolica de Cuyo. Facultad de Ciencias Quimicas y Tecnologicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Bergam, Ivana. Croatia Osiguranje Pension Company; Croacia
Fil: Inserra, Felipe. Universidad Maimónides; Argentina
Fil: Ferder, Leon Fernando. Universidad Maimónides; Argentina
Fil: Reiter, Russel. University Of Texas Health Science Center At San Antonio (ut Health San Antonio) ; University Of Texas At San Antonio; Estados Unidos
Fil: Manucha, Walter Ariel Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina. Universidad Nacional de Cuyo; Argentina
Materia
COVID-19
GEOGRAPHICAL DIFFERENCES
SEASONAL IMMUNE SYSTEM
VITAMIN D DEFICIENCY
VITAMIN D STATUS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/135204
Acceder
id CONICETDig_e930339c2612fb5536617405b956f243
oai_identifier_str oai:ri.conicet.gov.ar:11336/135204
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling COVID-19 pandemic and vitamin D deficiency: a different approach with an analysis of the findings and a complimentary proposalMartín Giménez, Virna MargaritaBergam, IvanaInserra, FelipeFerder, Leon FernandoReiter, RusselManucha, Walter Ariel FernandoCOVID-19GEOGRAPHICAL DIFFERENCESSEASONAL IMMUNE SYSTEMVITAMIN D DEFICIENCYVITAMIN D STATUShttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Vitamin D is an essential immune-modulator with receptors widely distributed throughout the body, and its serum levels fluctuate significantly among individuals between winter and summer months (from 30 to 50%). This study examines the association between low vitamin D status and prevalence of COVID-19 cases around the world and proposes a relationship between the seasonal character of the human immune system strength rather than to the seasonal infectivity of viruses. Also, this review suggests the observed geographical disparities in COVID-19 infections were due to differences in vitamin D levels. On the international scale, serum vitamin D levels are reportedly lowest in China, the Middle East, and South Europe; these populations also had the largest outbreaks of COVID-19 cases. In addition to the geographical differences in vitamin D status, there are known risk groups (ethnic, age-related, pregnancies). On the contrary, some countries including Canada, Finland, and North Europe incorporate increased amounts of vitamin D through fortified foods, vitamin D supplements, and sunbathing. These countries show the lowest morbidity and mortality rates by COVID-19 infection and demonstrate that lower ambient temperatures do not contribute to a higher number of COVID-19 cases. COVID-19 has spread around the globe almost simultaneously in both warm and cold areas. Given this information, vitamin D measurement should become an essential component of public health monitoring as a biomarker of immunity status. Clinical trials should be conducted to confirm this hypothesis. COVID-19 tests should be performed together with vitamin D status tests to verify this proposed relationship.Fil: Martín Giménez, Virna Margarita. Universidad Catolica de Cuyo. Facultad de Ciencias Quimicas y Tecnologicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Bergam, Ivana. Croatia Osiguranje Pension Company; CroaciaFil: Inserra, Felipe. Universidad Maimónides; ArgentinaFil: Ferder, Leon Fernando. Universidad Maimónides; ArgentinaFil: Reiter, Russel. University Of Texas Health Science Center At San Antonio (ut Health San Antonio) ; University Of Texas At San Antonio; Estados UnidosFil: Manucha, Walter Ariel Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina. Universidad Nacional de Cuyo; ArgentinaRangsit University2021-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/135204Martín Giménez, Virna Margarita; Bergam, Ivana; Inserra, Felipe; Ferder, Leon Fernando; Reiter, Russel; et al.; COVID-19 pandemic and vitamin D deficiency: a different approach with an analysis of the findings and a complimentary proposal; Rangsit University; Journal of Current Research and Technology; 11; 1; 1-2021; 148-1572077-03832630-0656CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.14456/jcst.2021.16info:eu-repo/semantics/altIdentifier/url/https://jcst.rsu.ac.th/volume/11/number/3/article/208info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:01:33Zoai:ri.conicet.gov.ar:11336/135204instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:01:33.668CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv COVID-19 pandemic and vitamin D deficiency: a different approach with an analysis of the findings and a complimentary proposal
title COVID-19 pandemic and vitamin D deficiency: a different approach with an analysis of the findings and a complimentary proposal
spellingShingle COVID-19 pandemic and vitamin D deficiency: a different approach with an analysis of the findings and a complimentary proposal
Martín Giménez, Virna Margarita
COVID-19
GEOGRAPHICAL DIFFERENCES
SEASONAL IMMUNE SYSTEM
VITAMIN D DEFICIENCY
VITAMIN D STATUS
title_short COVID-19 pandemic and vitamin D deficiency: a different approach with an analysis of the findings and a complimentary proposal
title_full COVID-19 pandemic and vitamin D deficiency: a different approach with an analysis of the findings and a complimentary proposal
title_fullStr COVID-19 pandemic and vitamin D deficiency: a different approach with an analysis of the findings and a complimentary proposal
title_full_unstemmed COVID-19 pandemic and vitamin D deficiency: a different approach with an analysis of the findings and a complimentary proposal
title_sort COVID-19 pandemic and vitamin D deficiency: a different approach with an analysis of the findings and a complimentary proposal
dc.creator.none.fl_str_mv Martín Giménez, Virna Margarita
Bergam, Ivana
Inserra, Felipe
Ferder, Leon Fernando
Reiter, Russel
Manucha, Walter Ariel Fernando
author Martín Giménez, Virna Margarita
author_facet Martín Giménez, Virna Margarita
Bergam, Ivana
Inserra, Felipe
Ferder, Leon Fernando
Reiter, Russel
Manucha, Walter Ariel Fernando
author_role author
author2 Bergam, Ivana
Inserra, Felipe
Ferder, Leon Fernando
Reiter, Russel
Manucha, Walter Ariel Fernando
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv COVID-19
GEOGRAPHICAL DIFFERENCES
SEASONAL IMMUNE SYSTEM
VITAMIN D DEFICIENCY
VITAMIN D STATUS
topic COVID-19
GEOGRAPHICAL DIFFERENCES
SEASONAL IMMUNE SYSTEM
VITAMIN D DEFICIENCY
VITAMIN D STATUS
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Vitamin D is an essential immune-modulator with receptors widely distributed throughout the body, and its serum levels fluctuate significantly among individuals between winter and summer months (from 30 to 50%). This study examines the association between low vitamin D status and prevalence of COVID-19 cases around the world and proposes a relationship between the seasonal character of the human immune system strength rather than to the seasonal infectivity of viruses. Also, this review suggests the observed geographical disparities in COVID-19 infections were due to differences in vitamin D levels. On the international scale, serum vitamin D levels are reportedly lowest in China, the Middle East, and South Europe; these populations also had the largest outbreaks of COVID-19 cases. In addition to the geographical differences in vitamin D status, there are known risk groups (ethnic, age-related, pregnancies). On the contrary, some countries including Canada, Finland, and North Europe incorporate increased amounts of vitamin D through fortified foods, vitamin D supplements, and sunbathing. These countries show the lowest morbidity and mortality rates by COVID-19 infection and demonstrate that lower ambient temperatures do not contribute to a higher number of COVID-19 cases. COVID-19 has spread around the globe almost simultaneously in both warm and cold areas. Given this information, vitamin D measurement should become an essential component of public health monitoring as a biomarker of immunity status. Clinical trials should be conducted to confirm this hypothesis. COVID-19 tests should be performed together with vitamin D status tests to verify this proposed relationship.
Fil: Martín Giménez, Virna Margarita. Universidad Catolica de Cuyo. Facultad de Ciencias Quimicas y Tecnologicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Bergam, Ivana. Croatia Osiguranje Pension Company; Croacia
Fil: Inserra, Felipe. Universidad Maimónides; Argentina
Fil: Ferder, Leon Fernando. Universidad Maimónides; Argentina
Fil: Reiter, Russel. University Of Texas Health Science Center At San Antonio (ut Health San Antonio) ; University Of Texas At San Antonio; Estados Unidos
Fil: Manucha, Walter Ariel Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina. Universidad Nacional de Cuyo; Argentina
description Vitamin D is an essential immune-modulator with receptors widely distributed throughout the body, and its serum levels fluctuate significantly among individuals between winter and summer months (from 30 to 50%). This study examines the association between low vitamin D status and prevalence of COVID-19 cases around the world and proposes a relationship between the seasonal character of the human immune system strength rather than to the seasonal infectivity of viruses. Also, this review suggests the observed geographical disparities in COVID-19 infections were due to differences in vitamin D levels. On the international scale, serum vitamin D levels are reportedly lowest in China, the Middle East, and South Europe; these populations also had the largest outbreaks of COVID-19 cases. In addition to the geographical differences in vitamin D status, there are known risk groups (ethnic, age-related, pregnancies). On the contrary, some countries including Canada, Finland, and North Europe incorporate increased amounts of vitamin D through fortified foods, vitamin D supplements, and sunbathing. These countries show the lowest morbidity and mortality rates by COVID-19 infection and demonstrate that lower ambient temperatures do not contribute to a higher number of COVID-19 cases. COVID-19 has spread around the globe almost simultaneously in both warm and cold areas. Given this information, vitamin D measurement should become an essential component of public health monitoring as a biomarker of immunity status. Clinical trials should be conducted to confirm this hypothesis. COVID-19 tests should be performed together with vitamin D status tests to verify this proposed relationship.
publishDate 2021
dc.date.none.fl_str_mv 2021-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/135204
Martín Giménez, Virna Margarita; Bergam, Ivana; Inserra, Felipe; Ferder, Leon Fernando; Reiter, Russel; et al.; COVID-19 pandemic and vitamin D deficiency: a different approach with an analysis of the findings and a complimentary proposal; Rangsit University; Journal of Current Research and Technology; 11; 1; 1-2021; 148-157
2077-0383
2630-0656
CONICET Digital
CONICET
url http://hdl.handle.net/11336/135204
identifier_str_mv Martín Giménez, Virna Margarita; Bergam, Ivana; Inserra, Felipe; Ferder, Leon Fernando; Reiter, Russel; et al.; COVID-19 pandemic and vitamin D deficiency: a different approach with an analysis of the findings and a complimentary proposal; Rangsit University; Journal of Current Research and Technology; 11; 1; 1-2021; 148-157
2077-0383
2630-0656
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.14456/jcst.2021.16
info:eu-repo/semantics/altIdentifier/url/https://jcst.rsu.ac.th/volume/11/number/3/article/208
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Rangsit University
publisher.none.fl_str_mv Rangsit University
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846781202248237056
score 12.982451

Publicaciones similares