Measurement of 10B concentration through autoradiography images in polycarbonate nuclear track detectors

Autores
Portu, Agustina Mariana; Bernaola, Omar Alberto; Nievas, Susana Isabel; Liberman, Sara; Saint Martin, María Laura Gisela
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The determination of the local concentration of boron in the different regions of tissue samples treated by Boron Neutron Capture Therapy (BNCT) could be made through the evaluation of the number of tracks forming autoradiography images. It is necessary to get a "standard" material containing a known amount of 10B, to correlate the number of tracks and boron concentration, i.e. to be used as a reference. Different systems were tested in order to find a suitable standard. Films made of 2% agarose in boron solutions showed a homogeneous distribution of the 10B atoms in the material structure. This system is easy handled and its physical properties are satisfactory. On the other hand, a small volume polycarbonate box was designed to contain 10B solutions of known concentration. This system showed a reduced number of background tracks and a promising behavior in many aspects. There is proportionality between track numbers per surface unit and 10B concentration, and between track numbers per surface unit and neutron fluence. Experimental results were compared to calculated values through formulas developed for thick samples autoradiography.
Fil: Portu, Agustina Mariana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina
Fil: Bernaola, Omar Alberto. Comisión Nacional de Energía Atómica. Gerencia de Area de Aplicaciones de la Tecnología Nuclear. Gerencia de Radiobiología (Centro Atómico Constituyentes); Argentina
Fil: Nievas, Susana Isabel. Comisión Nacional de Energía Atómica; Argentina
Fil: Liberman, Sara. Comisión Nacional de Energía Atómica; Argentina
Fil: Saint Martin, María Laura Gisela. Comisión Nacional de Energía Atómica. Gerencia de Area de Aplicaciones de la Tecnología Nuclear. Gerencia de Radiobiología (Centro Atómico Constituyentes); Argentina
Materia
AUTORADIOGRAPHY
BNCT
BORON IMAGING
NUCLEAR TRACKS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/188808
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Measurement of 10B concentration through autoradiography images in polycarbonate nuclear track detectorsPortu, Agustina MarianaBernaola, Omar AlbertoNievas, Susana IsabelLiberman, SaraSaint Martin, María Laura GiselaAUTORADIOGRAPHYBNCTBORON IMAGINGNUCLEAR TRACKShttps://purl.org/becyt/ford/1.3https://purl.org/becyt/ford/1The determination of the local concentration of boron in the different regions of tissue samples treated by Boron Neutron Capture Therapy (BNCT) could be made through the evaluation of the number of tracks forming autoradiography images. It is necessary to get a "standard" material containing a known amount of 10B, to correlate the number of tracks and boron concentration, i.e. to be used as a reference. Different systems were tested in order to find a suitable standard. Films made of 2% agarose in boron solutions showed a homogeneous distribution of the 10B atoms in the material structure. This system is easy handled and its physical properties are satisfactory. On the other hand, a small volume polycarbonate box was designed to contain 10B solutions of known concentration. This system showed a reduced number of background tracks and a promising behavior in many aspects. There is proportionality between track numbers per surface unit and 10B concentration, and between track numbers per surface unit and neutron fluence. Experimental results were compared to calculated values through formulas developed for thick samples autoradiography.Fil: Portu, Agustina Mariana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; ArgentinaFil: Bernaola, Omar Alberto. Comisión Nacional de Energía Atómica. Gerencia de Area de Aplicaciones de la Tecnología Nuclear. Gerencia de Radiobiología (Centro Atómico Constituyentes); ArgentinaFil: Nievas, Susana Isabel. Comisión Nacional de Energía Atómica; ArgentinaFil: Liberman, Sara. Comisión Nacional de Energía Atómica; ArgentinaFil: Saint Martin, María Laura Gisela. Comisión Nacional de Energía Atómica. Gerencia de Area de Aplicaciones de la Tecnología Nuclear. Gerencia de Radiobiología (Centro Atómico Constituyentes); ArgentinaPergamon-Elsevier Science Ltd2011-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/188808Portu, Agustina Mariana; Bernaola, Omar Alberto; Nievas, Susana Isabel; Liberman, Sara; Saint Martin, María Laura Gisela; Measurement of 10B concentration through autoradiography images in polycarbonate nuclear track detectors; Pergamon-Elsevier Science Ltd; Radiation Measurements; 46; 10; 10-2011; 1154-11591350-4487CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S1350448711003799info:eu-repo/semantics/altIdentifier/doi/10.1016/j.radmeas.2011.07.034info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:42:12Zoai:ri.conicet.gov.ar:11336/188808instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:42:12.676CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Measurement of 10B concentration through autoradiography images in polycarbonate nuclear track detectors
title Measurement of 10B concentration through autoradiography images in polycarbonate nuclear track detectors
spellingShingle Measurement of 10B concentration through autoradiography images in polycarbonate nuclear track detectors
Portu, Agustina Mariana
AUTORADIOGRAPHY
BNCT
BORON IMAGING
NUCLEAR TRACKS
title_short Measurement of 10B concentration through autoradiography images in polycarbonate nuclear track detectors
title_full Measurement of 10B concentration through autoradiography images in polycarbonate nuclear track detectors
title_fullStr Measurement of 10B concentration through autoradiography images in polycarbonate nuclear track detectors
title_full_unstemmed Measurement of 10B concentration through autoradiography images in polycarbonate nuclear track detectors
title_sort Measurement of 10B concentration through autoradiography images in polycarbonate nuclear track detectors
dc.creator.none.fl_str_mv Portu, Agustina Mariana
Bernaola, Omar Alberto
Nievas, Susana Isabel
Liberman, Sara
Saint Martin, María Laura Gisela
author Portu, Agustina Mariana
author_facet Portu, Agustina Mariana
Bernaola, Omar Alberto
Nievas, Susana Isabel
Liberman, Sara
Saint Martin, María Laura Gisela
author_role author
author2 Bernaola, Omar Alberto
Nievas, Susana Isabel
Liberman, Sara
Saint Martin, María Laura Gisela
author2_role author
author
author
author
dc.subject.none.fl_str_mv AUTORADIOGRAPHY
BNCT
BORON IMAGING
NUCLEAR TRACKS
topic AUTORADIOGRAPHY
BNCT
BORON IMAGING
NUCLEAR TRACKS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The determination of the local concentration of boron in the different regions of tissue samples treated by Boron Neutron Capture Therapy (BNCT) could be made through the evaluation of the number of tracks forming autoradiography images. It is necessary to get a "standard" material containing a known amount of 10B, to correlate the number of tracks and boron concentration, i.e. to be used as a reference. Different systems were tested in order to find a suitable standard. Films made of 2% agarose in boron solutions showed a homogeneous distribution of the 10B atoms in the material structure. This system is easy handled and its physical properties are satisfactory. On the other hand, a small volume polycarbonate box was designed to contain 10B solutions of known concentration. This system showed a reduced number of background tracks and a promising behavior in many aspects. There is proportionality between track numbers per surface unit and 10B concentration, and between track numbers per surface unit and neutron fluence. Experimental results were compared to calculated values through formulas developed for thick samples autoradiography.
Fil: Portu, Agustina Mariana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina
Fil: Bernaola, Omar Alberto. Comisión Nacional de Energía Atómica. Gerencia de Area de Aplicaciones de la Tecnología Nuclear. Gerencia de Radiobiología (Centro Atómico Constituyentes); Argentina
Fil: Nievas, Susana Isabel. Comisión Nacional de Energía Atómica; Argentina
Fil: Liberman, Sara. Comisión Nacional de Energía Atómica; Argentina
Fil: Saint Martin, María Laura Gisela. Comisión Nacional de Energía Atómica. Gerencia de Area de Aplicaciones de la Tecnología Nuclear. Gerencia de Radiobiología (Centro Atómico Constituyentes); Argentina
description The determination of the local concentration of boron in the different regions of tissue samples treated by Boron Neutron Capture Therapy (BNCT) could be made through the evaluation of the number of tracks forming autoradiography images. It is necessary to get a "standard" material containing a known amount of 10B, to correlate the number of tracks and boron concentration, i.e. to be used as a reference. Different systems were tested in order to find a suitable standard. Films made of 2% agarose in boron solutions showed a homogeneous distribution of the 10B atoms in the material structure. This system is easy handled and its physical properties are satisfactory. On the other hand, a small volume polycarbonate box was designed to contain 10B solutions of known concentration. This system showed a reduced number of background tracks and a promising behavior in many aspects. There is proportionality between track numbers per surface unit and 10B concentration, and between track numbers per surface unit and neutron fluence. Experimental results were compared to calculated values through formulas developed for thick samples autoradiography.
publishDate 2011
dc.date.none.fl_str_mv 2011-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/188808
Portu, Agustina Mariana; Bernaola, Omar Alberto; Nievas, Susana Isabel; Liberman, Sara; Saint Martin, María Laura Gisela; Measurement of 10B concentration through autoradiography images in polycarbonate nuclear track detectors; Pergamon-Elsevier Science Ltd; Radiation Measurements; 46; 10; 10-2011; 1154-1159
1350-4487
CONICET Digital
CONICET
url http://hdl.handle.net/11336/188808
identifier_str_mv Portu, Agustina Mariana; Bernaola, Omar Alberto; Nievas, Susana Isabel; Liberman, Sara; Saint Martin, María Laura Gisela; Measurement of 10B concentration through autoradiography images in polycarbonate nuclear track detectors; Pergamon-Elsevier Science Ltd; Radiation Measurements; 46; 10; 10-2011; 1154-1159
1350-4487
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S1350448711003799
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.radmeas.2011.07.034
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844614454732390400
score 13.070432

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