Discriminability measures and time-frequency features: an application to vibrissal tactile discrimination

Autores
Pizá, Alvaro Gabriel; Farfan, Fernando Daniel; Albarracin, Ana Lia; Ruiz, Gabriel Alfredo; Felice, Carmelo Jose
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: Often, the first problem that the neuroscientist must face is to determine if a specific stimulus set applied to biological system produces specific, precise and well differentiated responses. New method: In the present study we have proposed four discriminability measures to evaluate the feasibility of differentiating experimental conditions: information measures based on information theory, percentage overlap based on Linacre method, Bhattacharyya distance and univariate standard distance. All discriminability measures were evaluated on experimental protocols related to vibrissal tactile discrimination. Results: Time–frequency features were extracted from afferent discharges and then, pairwise comparisons were realized by using the proposed discriminability measures. Our results reveal the existence of time–frequency patterns which allows differentiating of sweep conditions from multifiber recordings. Comparison with existing methods: Currently, statistical methods used to justify significant differences in experimental conditions have rigorous criteria that must be met for correct validation of results. Discriminability measures proposed here are robust and can be adjusted to different experimental conditions (time series, repeated measures, specific variables and other). Conclusions: Discriminability measures allowed determining the time intervals where two sweep situations have the highest probability to be differentiated from each other. High discriminability percentages were observed into protraction phase, although to a lesser degree, it was also observed in retraction phase. It was demonstrated that sensibility of discriminability measures are different. This revealing a greater ability to highlight percentage changes of pairwise comparisons. Finally, the methods here proposed can be adapted to other features of biological responses.
Fil: Pizá, Alvaro Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Investigaciones Biológicas. Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas; Argentina. Universidad Nacional de Tucuman. Facultad de Ciencias Exactas y Tecnología. Departamento de Bioingeniería. Laboratorio de Medios e Interfases; Argentina
Fil: Farfan, Fernando Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Investigaciones Biológicas. Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas; Argentina. Universidad Nacional de Tucuman. Facultad de Ciencias Exactas y Tecnología. Departamento de Bioingeniería. Laboratorio de Medios e Interfases; Argentina
Fil: Albarracin, Ana Lia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Investigaciones Biológicas. Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas; Argentina. Universidad Nacional de Tucuman. Facultad de Ciencias Exactas y Tecnología. Departamento de Bioingeniería. Laboratorio de Medios e Interfases; Argentina
Fil: Ruiz, Gabriel Alfredo. Universidad Nacional de Tucuman. Facultad de Ciencias Exactas y Tecnología. Departamento de Bioingeniería. Laboratorio de Medios e Interfases; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Felice, Carmelo Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Investigaciones Biológicas. Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas; Argentina. Universidad Nacional de Tucuman. Facultad de Ciencias Exactas y Tecnología. Departamento de Bioingeniería. Laboratorio de Medios e Interfases; Argentina
Materia
Information Theory
Discriminability
Spectrogram
Texture discrimination
Afferent activity
Vibrissae
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/30313
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/30313
network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Discriminability measures and time-frequency features: an application to vibrissal tactile discriminationPizá, Alvaro GabrielFarfan, Fernando DanielAlbarracin, Ana LiaRuiz, Gabriel AlfredoFelice, Carmelo JoseInformation TheoryDiscriminabilitySpectrogramTexture discriminationAfferent activityVibrissaehttps://purl.org/becyt/ford/1.2https://purl.org/becyt/ford/1Background: Often, the first problem that the neuroscientist must face is to determine if a specific stimulus set applied to biological system produces specific, precise and well differentiated responses. New method: In the present study we have proposed four discriminability measures to evaluate the feasibility of differentiating experimental conditions: information measures based on information theory, percentage overlap based on Linacre method, Bhattacharyya distance and univariate standard distance. All discriminability measures were evaluated on experimental protocols related to vibrissal tactile discrimination. Results: Time–frequency features were extracted from afferent discharges and then, pairwise comparisons were realized by using the proposed discriminability measures. Our results reveal the existence of time–frequency patterns which allows differentiating of sweep conditions from multifiber recordings. Comparison with existing methods: Currently, statistical methods used to justify significant differences in experimental conditions have rigorous criteria that must be met for correct validation of results. Discriminability measures proposed here are robust and can be adjusted to different experimental conditions (time series, repeated measures, specific variables and other). Conclusions: Discriminability measures allowed determining the time intervals where two sweep situations have the highest probability to be differentiated from each other. High discriminability percentages were observed into protraction phase, although to a lesser degree, it was also observed in retraction phase. It was demonstrated that sensibility of discriminability measures are different. This revealing a greater ability to highlight percentage changes of pairwise comparisons. Finally, the methods here proposed can be adapted to other features of biological responses.Fil: Pizá, Alvaro Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Investigaciones Biológicas. Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas; Argentina. Universidad Nacional de Tucuman. Facultad de Ciencias Exactas y Tecnología. Departamento de Bioingeniería. Laboratorio de Medios e Interfases; ArgentinaFil: Farfan, Fernando Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Investigaciones Biológicas. Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas; Argentina. Universidad Nacional de Tucuman. Facultad de Ciencias Exactas y Tecnología. Departamento de Bioingeniería. Laboratorio de Medios e Interfases; ArgentinaFil: Albarracin, Ana Lia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Investigaciones Biológicas. Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas; Argentina. Universidad Nacional de Tucuman. Facultad de Ciencias Exactas y Tecnología. Departamento de Bioingeniería. Laboratorio de Medios e Interfases; ArgentinaFil: Ruiz, Gabriel Alfredo. Universidad Nacional de Tucuman. Facultad de Ciencias Exactas y Tecnología. Departamento de Bioingeniería. Laboratorio de Medios e Interfases; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Felice, Carmelo Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Investigaciones Biológicas. Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas; Argentina. Universidad Nacional de Tucuman. Facultad de Ciencias Exactas y Tecnología. Departamento de Bioingeniería. Laboratorio de Medios e Interfases; ArgentinaElsevier Science2014-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/30313Pizá, Alvaro Gabriel; Farfan, Fernando Daniel; Albarracin, Ana Lia; Ruiz, Gabriel Alfredo; Felice, Carmelo Jose; Discriminability measures and time-frequency features: an application to vibrissal tactile discrimination; Elsevier Science; Journal of Neuroscience Methods; 233; 6-2014; 78-880165-0270CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.jneumeth.2014.06.007info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0165027014002131info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T12:01:39Zoai:ri.conicet.gov.ar:11336/30313instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 12:01:39.418CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Discriminability measures and time-frequency features: an application to vibrissal tactile discrimination
title Discriminability measures and time-frequency features: an application to vibrissal tactile discrimination
spellingShingle Discriminability measures and time-frequency features: an application to vibrissal tactile discrimination
Pizá, Alvaro Gabriel
Information Theory
Discriminability
Spectrogram
Texture discrimination
Afferent activity
Vibrissae
title_short Discriminability measures and time-frequency features: an application to vibrissal tactile discrimination
title_full Discriminability measures and time-frequency features: an application to vibrissal tactile discrimination
title_fullStr Discriminability measures and time-frequency features: an application to vibrissal tactile discrimination
title_full_unstemmed Discriminability measures and time-frequency features: an application to vibrissal tactile discrimination
title_sort Discriminability measures and time-frequency features: an application to vibrissal tactile discrimination
dc.creator.none.fl_str_mv Pizá, Alvaro Gabriel
Farfan, Fernando Daniel
Albarracin, Ana Lia
Ruiz, Gabriel Alfredo
Felice, Carmelo Jose
author Pizá, Alvaro Gabriel
author_facet Pizá, Alvaro Gabriel
Farfan, Fernando Daniel
Albarracin, Ana Lia
Ruiz, Gabriel Alfredo
Felice, Carmelo Jose
author_role author
author2 Farfan, Fernando Daniel
Albarracin, Ana Lia
Ruiz, Gabriel Alfredo
Felice, Carmelo Jose
author2_role author
author
author
author
dc.subject.none.fl_str_mv Information Theory
Discriminability
Spectrogram
Texture discrimination
Afferent activity
Vibrissae
topic Information Theory
Discriminability
Spectrogram
Texture discrimination
Afferent activity
Vibrissae
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.2
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Background: Often, the first problem that the neuroscientist must face is to determine if a specific stimulus set applied to biological system produces specific, precise and well differentiated responses. New method: In the present study we have proposed four discriminability measures to evaluate the feasibility of differentiating experimental conditions: information measures based on information theory, percentage overlap based on Linacre method, Bhattacharyya distance and univariate standard distance. All discriminability measures were evaluated on experimental protocols related to vibrissal tactile discrimination. Results: Time–frequency features were extracted from afferent discharges and then, pairwise comparisons were realized by using the proposed discriminability measures. Our results reveal the existence of time–frequency patterns which allows differentiating of sweep conditions from multifiber recordings. Comparison with existing methods: Currently, statistical methods used to justify significant differences in experimental conditions have rigorous criteria that must be met for correct validation of results. Discriminability measures proposed here are robust and can be adjusted to different experimental conditions (time series, repeated measures, specific variables and other). Conclusions: Discriminability measures allowed determining the time intervals where two sweep situations have the highest probability to be differentiated from each other. High discriminability percentages were observed into protraction phase, although to a lesser degree, it was also observed in retraction phase. It was demonstrated that sensibility of discriminability measures are different. This revealing a greater ability to highlight percentage changes of pairwise comparisons. Finally, the methods here proposed can be adapted to other features of biological responses.
Fil: Pizá, Alvaro Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Investigaciones Biológicas. Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas; Argentina. Universidad Nacional de Tucuman. Facultad de Ciencias Exactas y Tecnología. Departamento de Bioingeniería. Laboratorio de Medios e Interfases; Argentina
Fil: Farfan, Fernando Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Investigaciones Biológicas. Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas; Argentina. Universidad Nacional de Tucuman. Facultad de Ciencias Exactas y Tecnología. Departamento de Bioingeniería. Laboratorio de Medios e Interfases; Argentina
Fil: Albarracin, Ana Lia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Investigaciones Biológicas. Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas; Argentina. Universidad Nacional de Tucuman. Facultad de Ciencias Exactas y Tecnología. Departamento de Bioingeniería. Laboratorio de Medios e Interfases; Argentina
Fil: Ruiz, Gabriel Alfredo. Universidad Nacional de Tucuman. Facultad de Ciencias Exactas y Tecnología. Departamento de Bioingeniería. Laboratorio de Medios e Interfases; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Felice, Carmelo Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Investigaciones Biológicas. Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas; Argentina. Universidad Nacional de Tucuman. Facultad de Ciencias Exactas y Tecnología. Departamento de Bioingeniería. Laboratorio de Medios e Interfases; Argentina
description Background: Often, the first problem that the neuroscientist must face is to determine if a specific stimulus set applied to biological system produces specific, precise and well differentiated responses. New method: In the present study we have proposed four discriminability measures to evaluate the feasibility of differentiating experimental conditions: information measures based on information theory, percentage overlap based on Linacre method, Bhattacharyya distance and univariate standard distance. All discriminability measures were evaluated on experimental protocols related to vibrissal tactile discrimination. Results: Time–frequency features were extracted from afferent discharges and then, pairwise comparisons were realized by using the proposed discriminability measures. Our results reveal the existence of time–frequency patterns which allows differentiating of sweep conditions from multifiber recordings. Comparison with existing methods: Currently, statistical methods used to justify significant differences in experimental conditions have rigorous criteria that must be met for correct validation of results. Discriminability measures proposed here are robust and can be adjusted to different experimental conditions (time series, repeated measures, specific variables and other). Conclusions: Discriminability measures allowed determining the time intervals where two sweep situations have the highest probability to be differentiated from each other. High discriminability percentages were observed into protraction phase, although to a lesser degree, it was also observed in retraction phase. It was demonstrated that sensibility of discriminability measures are different. This revealing a greater ability to highlight percentage changes of pairwise comparisons. Finally, the methods here proposed can be adapted to other features of biological responses.
publishDate 2014
dc.date.none.fl_str_mv 2014-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/30313
Pizá, Alvaro Gabriel; Farfan, Fernando Daniel; Albarracin, Ana Lia; Ruiz, Gabriel Alfredo; Felice, Carmelo Jose; Discriminability measures and time-frequency features: an application to vibrissal tactile discrimination; Elsevier Science; Journal of Neuroscience Methods; 233; 6-2014; 78-88
0165-0270
CONICET Digital
CONICET
url http://hdl.handle.net/11336/30313
identifier_str_mv Pizá, Alvaro Gabriel; Farfan, Fernando Daniel; Albarracin, Ana Lia; Ruiz, Gabriel Alfredo; Felice, Carmelo Jose; Discriminability measures and time-frequency features: an application to vibrissal tactile discrimination; Elsevier Science; Journal of Neuroscience Methods; 233; 6-2014; 78-88
0165-0270
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jneumeth.2014.06.007
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0165027014002131
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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