Short- and Long-Term Outcomes of Every Graft Recovered During a Multi-Organ Procurement Procedure Including the Intestine
- Autores
- Farinelli, P. A.; Padin, J. M.; Troncoso J; Bertolotti, A.; Lenz, M.; Sanchez, N.; Fortunato, R.; Caravello, E.; Imperiali, N.; Dip, M.; Sanchez Claria, R; Arriola, M.; De Arteaga. J; Pujol Soler, G.; Bisigniano, L.; Gil, O; McCormack, L.; Botta, E.; Inventarza, O.; Gaite, L.; Hyon, Sung Ho; Raffaele, P.; Illanes, G; de Santibañez, E.; Favaloro R; Gondolesi, Gabriel Eduardo
- Año de publicación
- 2014
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Background: The development of intestinal transplant (Tx) programs introduces thymoglobulin donor treatment as well as an almost complete warm dissection of the abdominal organs to allocate them to different recipients. Our aim is to assess the reproducibility and feasibility of the surgical technique of multi-organ procurement with the use of thymoglobulin donor pre-treatment and report the short- and long-term outcomes of every graft harvested as part of multi-organ procurement (MTOp), including the intestine.MethodsData were collected of all organs harvested from MTOp, including the intestines allocated to our center from March 2006 to July 2011. Data from 92 recipients and 116 organs procured from 29 MTOp were analyzed. Twelve hearts, 2 lungs, and 1 cardio-pulmonary block were transplanted; primary graft dysfunction developed in 4 of the 12 hearts and in the cardio-pulmonary block.ResultsThe survival rate was 75% and 100% for hearts and lungs, respectively. Nineteen livers, 9 kidney-pancreas, 19 kidneys, and 29 intestines were transplanted. Delayed graft function (DGF) of the pancreas developed in 3 of 9 kidney-pancreas, and the other 3 exhibited DGF of the kidney; 4 of 19 Tx kidneys had DGF. The survival was 84%, 78%, 95%, and 65.5% for livers, kidney-pancreas, kidneys, and intestines, respectively.ConclusionsOrgans procured during MTOp including the intestine can be safely used, increasing organ availability and transplant applicability without compromising allocation, quality, and long-term results of the non-intestinal?procured organs.
Fil: Farinelli, P. A.. Universidad Favaloro. Área de Investigación y Desarrollo; Argentina
Fil: Padin, J. M.. Universidad Favaloro; Argentina. Universidad Favaloro. Área de Investigación y Desarrollo; Argentina
Fil: Troncoso J. Instituto Nacional Central Único Coordinador de Ablación e Implante (INCUCAI); Argentina
Fil: Bertolotti, A.. Universidad Favaloro. Área de Investigación y Desarrollo; Argentina
Fil: Lenz, M.. Hospital Italiano; Argentina
Fil: Sanchez, N.. Instituto de Nefrología de Buenos Aires; Argentina
Fil: Fortunato, R.. Universidad Favaloro. Área de Investigación y Desarrollo; Argentina
Fil: Caravello, E.. Hospital Italiano; Argentina
Fil: Imperiali, N.. Hospital Italiano; Argentina
Fil: Dip, M.. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
Fil: Sanchez Claria, R. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
Fil: Arriola, M.. Clínica de Nefrología, Urología y Enfermedades Cardiovasculares de la Ciudad de Santa Fe; Argentina
Fil: De Arteaga. J. Hospital Privado de Córdoba; Argentina
Fil: Pujol Soler, G.. Centro de Educación Médica e Investigaciones Clínicas “Norberto Quirno”; Argentina
Fil: Bisigniano, L.. Instituto Nacional Central Único Coordinador de Ablación e Implante (INCUCAI); Argentina
Fil: Gil, O. Sanatorio Allende; Argentina
Fil: McCormack, L.. Hospital Aleman; Argentina
Fil: Botta, E.. Clínica de Nefrología, Urología y Enfermedades Cardiovasculares de la Ciudad de Santa Fe; Argentina
Fil: Inventarza, O.. Ministerio de Defensa. Ejército Argentino. Hospital Militar Central Cirujano Mayor "Dr. Cosme Argerich"; Argentina
Fil: Gaite, L.. Clínica de Nefrología, Urología y Enfermedades Cardiovasculares de la Ciudad de Santa Fe; Argentina
Fil: Hyon, Sung Ho. Hospital Italiano; Argentina
Fil: Raffaele, P.. Universidad Favaloro. Área de Investigación y Desarrollo; Argentina
Fil: Illanes, G. Clínica de Nefrología, Urología y Enfermedades Cardiovasculares de la Ciudad de Santa Fe; Argentina
Fil: de Santibañez, E.. Hospital Italiano; Argentina
Fil: Favaloro R. Universidad Favaloro. Área de Investigación y Desarrollo; Argentina
Fil: Gondolesi, Gabriel Eduardo. Universidad Favaloro. Área de Investigación y Desarrollo; Argentina - Materia
-
Procurement Procedure
Graft Recovered
Outcomes - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
.jpg)
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/36143
Ver los metadatos del registro completo
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Short- and Long-Term Outcomes of Every Graft Recovered During a Multi-Organ Procurement Procedure Including the IntestineFarinelli, P. A.Padin, J. M.Troncoso JBertolotti, A.Lenz, M.Sanchez, N.Fortunato, R.Caravello, E.Imperiali, N.Dip, M.Sanchez Claria, RArriola, M.De Arteaga. JPujol Soler, G.Bisigniano, L.Gil, OMcCormack, L.Botta, E.Inventarza, O.Gaite, L.Hyon, Sung HoRaffaele, P.Illanes, Gde Santibañez, E.Favaloro RGondolesi, Gabriel EduardoProcurement ProcedureGraft RecoveredOutcomeshttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Background: The development of intestinal transplant (Tx) programs introduces thymoglobulin donor treatment as well as an almost complete warm dissection of the abdominal organs to allocate them to different recipients. Our aim is to assess the reproducibility and feasibility of the surgical technique of multi-organ procurement with the use of thymoglobulin donor pre-treatment and report the short- and long-term outcomes of every graft harvested as part of multi-organ procurement (MTOp), including the intestine.MethodsData were collected of all organs harvested from MTOp, including the intestines allocated to our center from March 2006 to July 2011. Data from 92 recipients and 116 organs procured from 29 MTOp were analyzed. Twelve hearts, 2 lungs, and 1 cardio-pulmonary block were transplanted; primary graft dysfunction developed in 4 of the 12 hearts and in the cardio-pulmonary block.ResultsThe survival rate was 75% and 100% for hearts and lungs, respectively. Nineteen livers, 9 kidney-pancreas, 19 kidneys, and 29 intestines were transplanted. Delayed graft function (DGF) of the pancreas developed in 3 of 9 kidney-pancreas, and the other 3 exhibited DGF of the kidney; 4 of 19 Tx kidneys had DGF. The survival was 84%, 78%, 95%, and 65.5% for livers, kidney-pancreas, kidneys, and intestines, respectively.ConclusionsOrgans procured during MTOp including the intestine can be safely used, increasing organ availability and transplant applicability without compromising allocation, quality, and long-term results of the non-intestinal?procured organs.Fil: Farinelli, P. A.. Universidad Favaloro. Área de Investigación y Desarrollo; ArgentinaFil: Padin, J. M.. Universidad Favaloro; Argentina. Universidad Favaloro. Área de Investigación y Desarrollo; ArgentinaFil: Troncoso J. Instituto Nacional Central Único Coordinador de Ablación e Implante (INCUCAI); ArgentinaFil: Bertolotti, A.. Universidad Favaloro. Área de Investigación y Desarrollo; ArgentinaFil: Lenz, M.. Hospital Italiano; ArgentinaFil: Sanchez, N.. Instituto de Nefrología de Buenos Aires; ArgentinaFil: Fortunato, R.. Universidad Favaloro. Área de Investigación y Desarrollo; ArgentinaFil: Caravello, E.. Hospital Italiano; ArgentinaFil: Imperiali, N.. Hospital Italiano; ArgentinaFil: Dip, M.. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaFil: Sanchez Claria, R. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaFil: Arriola, M.. Clínica de Nefrología, Urología y Enfermedades Cardiovasculares de la Ciudad de Santa Fe; ArgentinaFil: De Arteaga. J. Hospital Privado de Córdoba; ArgentinaFil: Pujol Soler, G.. Centro de Educación Médica e Investigaciones Clínicas “Norberto Quirno”; ArgentinaFil: Bisigniano, L.. Instituto Nacional Central Único Coordinador de Ablación e Implante (INCUCAI); ArgentinaFil: Gil, O. Sanatorio Allende; ArgentinaFil: McCormack, L.. Hospital Aleman; ArgentinaFil: Botta, E.. Clínica de Nefrología, Urología y Enfermedades Cardiovasculares de la Ciudad de Santa Fe; ArgentinaFil: Inventarza, O.. Ministerio de Defensa. Ejército Argentino. Hospital Militar Central Cirujano Mayor "Dr. Cosme Argerich"; ArgentinaFil: Gaite, L.. Clínica de Nefrología, Urología y Enfermedades Cardiovasculares de la Ciudad de Santa Fe; ArgentinaFil: Hyon, Sung Ho. Hospital Italiano; ArgentinaFil: Raffaele, P.. Universidad Favaloro. Área de Investigación y Desarrollo; ArgentinaFil: Illanes, G. Clínica de Nefrología, Urología y Enfermedades Cardiovasculares de la Ciudad de Santa Fe; ArgentinaFil: de Santibañez, E.. Hospital Italiano; ArgentinaFil: Favaloro R. Universidad Favaloro. Área de Investigación y Desarrollo; ArgentinaFil: Gondolesi, Gabriel Eduardo. Universidad Favaloro. Área de Investigación y Desarrollo; ArgentinaElsevier Science Inc2014-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/36143Farinelli, P. A.; Padin, J. M.; Troncoso J; Bertolotti, A.; Lenz, M.; et al.; Short- and Long-Term Outcomes of Every Graft Recovered During a Multi-Organ Procurement Procedure Including the Intestine; Elsevier Science Inc; Transplantation Proceedings; 46; 8-2014; 2090-20950041-1345CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.transproceed.2014.06.040info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0041134514004746info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:38:56Zoai:ri.conicet.gov.ar:11336/36143instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:38:56.665CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
| dc.title.none.fl_str_mv |
Short- and Long-Term Outcomes of Every Graft Recovered During a Multi-Organ Procurement Procedure Including the Intestine |
| title |
Short- and Long-Term Outcomes of Every Graft Recovered During a Multi-Organ Procurement Procedure Including the Intestine |
| spellingShingle |
Short- and Long-Term Outcomes of Every Graft Recovered During a Multi-Organ Procurement Procedure Including the Intestine Farinelli, P. A. Procurement Procedure Graft Recovered Outcomes |
| title_short |
Short- and Long-Term Outcomes of Every Graft Recovered During a Multi-Organ Procurement Procedure Including the Intestine |
| title_full |
Short- and Long-Term Outcomes of Every Graft Recovered During a Multi-Organ Procurement Procedure Including the Intestine |
| title_fullStr |
Short- and Long-Term Outcomes of Every Graft Recovered During a Multi-Organ Procurement Procedure Including the Intestine |
| title_full_unstemmed |
Short- and Long-Term Outcomes of Every Graft Recovered During a Multi-Organ Procurement Procedure Including the Intestine |
| title_sort |
Short- and Long-Term Outcomes of Every Graft Recovered During a Multi-Organ Procurement Procedure Including the Intestine |
| dc.creator.none.fl_str_mv |
Farinelli, P. A. Padin, J. M. Troncoso J Bertolotti, A. Lenz, M. Sanchez, N. Fortunato, R. Caravello, E. Imperiali, N. Dip, M. Sanchez Claria, R Arriola, M. De Arteaga. J Pujol Soler, G. Bisigniano, L. Gil, O McCormack, L. Botta, E. Inventarza, O. Gaite, L. Hyon, Sung Ho Raffaele, P. Illanes, G de Santibañez, E. Favaloro R Gondolesi, Gabriel Eduardo |
| author |
Farinelli, P. A. |
| author_facet |
Farinelli, P. A. Padin, J. M. Troncoso J Bertolotti, A. Lenz, M. Sanchez, N. Fortunato, R. Caravello, E. Imperiali, N. Dip, M. Sanchez Claria, R Arriola, M. De Arteaga. J Pujol Soler, G. Bisigniano, L. Gil, O McCormack, L. Botta, E. Inventarza, O. Gaite, L. Hyon, Sung Ho Raffaele, P. Illanes, G de Santibañez, E. Favaloro R Gondolesi, Gabriel Eduardo |
| author_role |
author |
| author2 |
Padin, J. M. Troncoso J Bertolotti, A. Lenz, M. Sanchez, N. Fortunato, R. Caravello, E. Imperiali, N. Dip, M. Sanchez Claria, R Arriola, M. De Arteaga. J Pujol Soler, G. Bisigniano, L. Gil, O McCormack, L. Botta, E. Inventarza, O. Gaite, L. Hyon, Sung Ho Raffaele, P. Illanes, G de Santibañez, E. Favaloro R Gondolesi, Gabriel Eduardo |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.subject.none.fl_str_mv |
Procurement Procedure Graft Recovered Outcomes |
| topic |
Procurement Procedure Graft Recovered Outcomes |
| purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.2 https://purl.org/becyt/ford/3 |
| dc.description.none.fl_txt_mv |
Background: The development of intestinal transplant (Tx) programs introduces thymoglobulin donor treatment as well as an almost complete warm dissection of the abdominal organs to allocate them to different recipients. Our aim is to assess the reproducibility and feasibility of the surgical technique of multi-organ procurement with the use of thymoglobulin donor pre-treatment and report the short- and long-term outcomes of every graft harvested as part of multi-organ procurement (MTOp), including the intestine.MethodsData were collected of all organs harvested from MTOp, including the intestines allocated to our center from March 2006 to July 2011. Data from 92 recipients and 116 organs procured from 29 MTOp were analyzed. Twelve hearts, 2 lungs, and 1 cardio-pulmonary block were transplanted; primary graft dysfunction developed in 4 of the 12 hearts and in the cardio-pulmonary block.ResultsThe survival rate was 75% and 100% for hearts and lungs, respectively. Nineteen livers, 9 kidney-pancreas, 19 kidneys, and 29 intestines were transplanted. Delayed graft function (DGF) of the pancreas developed in 3 of 9 kidney-pancreas, and the other 3 exhibited DGF of the kidney; 4 of 19 Tx kidneys had DGF. The survival was 84%, 78%, 95%, and 65.5% for livers, kidney-pancreas, kidneys, and intestines, respectively.ConclusionsOrgans procured during MTOp including the intestine can be safely used, increasing organ availability and transplant applicability without compromising allocation, quality, and long-term results of the non-intestinal?procured organs. Fil: Farinelli, P. A.. Universidad Favaloro. Área de Investigación y Desarrollo; Argentina Fil: Padin, J. M.. Universidad Favaloro; Argentina. Universidad Favaloro. Área de Investigación y Desarrollo; Argentina Fil: Troncoso J. Instituto Nacional Central Único Coordinador de Ablación e Implante (INCUCAI); Argentina Fil: Bertolotti, A.. Universidad Favaloro. Área de Investigación y Desarrollo; Argentina Fil: Lenz, M.. Hospital Italiano; Argentina Fil: Sanchez, N.. Instituto de Nefrología de Buenos Aires; Argentina Fil: Fortunato, R.. Universidad Favaloro. Área de Investigación y Desarrollo; Argentina Fil: Caravello, E.. Hospital Italiano; Argentina Fil: Imperiali, N.. Hospital Italiano; Argentina Fil: Dip, M.. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina Fil: Sanchez Claria, R. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina Fil: Arriola, M.. Clínica de Nefrología, Urología y Enfermedades Cardiovasculares de la Ciudad de Santa Fe; Argentina Fil: De Arteaga. J. Hospital Privado de Córdoba; Argentina Fil: Pujol Soler, G.. Centro de Educación Médica e Investigaciones Clínicas “Norberto Quirno”; Argentina Fil: Bisigniano, L.. Instituto Nacional Central Único Coordinador de Ablación e Implante (INCUCAI); Argentina Fil: Gil, O. Sanatorio Allende; Argentina Fil: McCormack, L.. Hospital Aleman; Argentina Fil: Botta, E.. Clínica de Nefrología, Urología y Enfermedades Cardiovasculares de la Ciudad de Santa Fe; Argentina Fil: Inventarza, O.. Ministerio de Defensa. Ejército Argentino. Hospital Militar Central Cirujano Mayor "Dr. Cosme Argerich"; Argentina Fil: Gaite, L.. Clínica de Nefrología, Urología y Enfermedades Cardiovasculares de la Ciudad de Santa Fe; Argentina Fil: Hyon, Sung Ho. Hospital Italiano; Argentina Fil: Raffaele, P.. Universidad Favaloro. Área de Investigación y Desarrollo; Argentina Fil: Illanes, G. Clínica de Nefrología, Urología y Enfermedades Cardiovasculares de la Ciudad de Santa Fe; Argentina Fil: de Santibañez, E.. Hospital Italiano; Argentina Fil: Favaloro R. Universidad Favaloro. Área de Investigación y Desarrollo; Argentina Fil: Gondolesi, Gabriel Eduardo. Universidad Favaloro. Área de Investigación y Desarrollo; Argentina |
| description |
Background: The development of intestinal transplant (Tx) programs introduces thymoglobulin donor treatment as well as an almost complete warm dissection of the abdominal organs to allocate them to different recipients. Our aim is to assess the reproducibility and feasibility of the surgical technique of multi-organ procurement with the use of thymoglobulin donor pre-treatment and report the short- and long-term outcomes of every graft harvested as part of multi-organ procurement (MTOp), including the intestine.MethodsData were collected of all organs harvested from MTOp, including the intestines allocated to our center from March 2006 to July 2011. Data from 92 recipients and 116 organs procured from 29 MTOp were analyzed. Twelve hearts, 2 lungs, and 1 cardio-pulmonary block were transplanted; primary graft dysfunction developed in 4 of the 12 hearts and in the cardio-pulmonary block.ResultsThe survival rate was 75% and 100% for hearts and lungs, respectively. Nineteen livers, 9 kidney-pancreas, 19 kidneys, and 29 intestines were transplanted. Delayed graft function (DGF) of the pancreas developed in 3 of 9 kidney-pancreas, and the other 3 exhibited DGF of the kidney; 4 of 19 Tx kidneys had DGF. The survival was 84%, 78%, 95%, and 65.5% for livers, kidney-pancreas, kidneys, and intestines, respectively.ConclusionsOrgans procured during MTOp including the intestine can be safely used, increasing organ availability and transplant applicability without compromising allocation, quality, and long-term results of the non-intestinal?procured organs. |
| publishDate |
2014 |
| dc.date.none.fl_str_mv |
2014-08 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/36143 Farinelli, P. A.; Padin, J. M.; Troncoso J; Bertolotti, A.; Lenz, M.; et al.; Short- and Long-Term Outcomes of Every Graft Recovered During a Multi-Organ Procurement Procedure Including the Intestine; Elsevier Science Inc; Transplantation Proceedings; 46; 8-2014; 2090-2095 0041-1345 CONICET Digital CONICET |
| url |
http://hdl.handle.net/11336/36143 |
| identifier_str_mv |
Farinelli, P. A.; Padin, J. M.; Troncoso J; Bertolotti, A.; Lenz, M.; et al.; Short- and Long-Term Outcomes of Every Graft Recovered During a Multi-Organ Procurement Procedure Including the Intestine; Elsevier Science Inc; Transplantation Proceedings; 46; 8-2014; 2090-2095 0041-1345 CONICET Digital CONICET |
| dc.language.none.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.transproceed.2014.06.040 info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0041134514004746 |
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info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
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openAccess |
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https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
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application/pdf application/pdf application/pdf |
| dc.publisher.none.fl_str_mv |
Elsevier Science Inc |
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Elsevier Science Inc |
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reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
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dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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13.22299 |