Study of the participation of caffeine and polyphenols on the overall antioxidant activity of mate (Ilex paraguariensis)

Autores
Anesini, Claudia Alejandra; Turner, Sebastian Ariel; Cogoi, Laura Carolina; Filip, Rosana
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The aim of this work was to investigate the participation of the main bioactive compounds (caffeine, caffeic acid derivatives and rutin) on the antioxidant activity (DPPH free radical scavenging activity and the prevention of lipid peroxidation) of the crude extracts of Ilex paraguariensis. Green and commercial products were used to prepare aqueous extracts. The main bioactive compounds were identified and quantified by HPLC-DAD. The antioxidant activities of the pure compounds in the concentrations present in the extracts were also analyzed. Results demonstrated that chlorogenic acid, caffeic acid and rutin contribute to the antioxidant activity. On the contrary, caffeine induced lipid peroxidation of linoleic acid acting as a pro-oxidant compound. The caffeine content in the green extracts was lower when compared to the commercial extracts. The antioxidant and pro-oxidant antagonistic effects of the compounds in the amounts present in the extracts resulted in higher antioxidant potency of the green extracts when compared to the commercial ones, as demonstrated by the EC 50 values and without affecting the maximum efficiency displayed by the extracts.
Fil: Anesini, Claudia Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
Fil: Turner, Sebastian Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
Fil: Cogoi, Laura Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
Fil: Filip, Rosana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
Materia
Antioxidant
Caffeine
Ilex paraguariensis
Mate
Polyphenols
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/271120
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/271120
network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Study of the participation of caffeine and polyphenols on the overall antioxidant activity of mate (Ilex paraguariensis)Anesini, Claudia AlejandraTurner, Sebastian ArielCogoi, Laura CarolinaFilip, RosanaAntioxidantCaffeineIlex paraguariensisMatePolyphenolshttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3The aim of this work was to investigate the participation of the main bioactive compounds (caffeine, caffeic acid derivatives and rutin) on the antioxidant activity (DPPH free radical scavenging activity and the prevention of lipid peroxidation) of the crude extracts of Ilex paraguariensis. Green and commercial products were used to prepare aqueous extracts. The main bioactive compounds were identified and quantified by HPLC-DAD. The antioxidant activities of the pure compounds in the concentrations present in the extracts were also analyzed. Results demonstrated that chlorogenic acid, caffeic acid and rutin contribute to the antioxidant activity. On the contrary, caffeine induced lipid peroxidation of linoleic acid acting as a pro-oxidant compound. The caffeine content in the green extracts was lower when compared to the commercial extracts. The antioxidant and pro-oxidant antagonistic effects of the compounds in the amounts present in the extracts resulted in higher antioxidant potency of the green extracts when compared to the commercial ones, as demonstrated by the EC 50 values and without affecting the maximum efficiency displayed by the extracts.Fil: Anesini, Claudia Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; ArgentinaFil: Turner, Sebastian Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; ArgentinaFil: Cogoi, Laura Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; ArgentinaFil: Filip, Rosana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; ArgentinaElsevier Science2012-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/271120Anesini, Claudia Alejandra; Turner, Sebastian Ariel; Cogoi, Laura Carolina; Filip, Rosana; Study of the participation of caffeine and polyphenols on the overall antioxidant activity of mate (Ilex paraguariensis); Elsevier Science; LWT - Food Science and Technology; 45; 2; 3-2012; 299-3040023-6438CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S0023643811001988info:eu-repo/semantics/altIdentifier/doi/10.1016/j.lwt.2011.06.015info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:19:06Zoai:ri.conicet.gov.ar:11336/271120instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:19:07.167CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Study of the participation of caffeine and polyphenols on the overall antioxidant activity of mate (Ilex paraguariensis)
title Study of the participation of caffeine and polyphenols on the overall antioxidant activity of mate (Ilex paraguariensis)
spellingShingle Study of the participation of caffeine and polyphenols on the overall antioxidant activity of mate (Ilex paraguariensis)
Anesini, Claudia Alejandra
Antioxidant
Caffeine
Ilex paraguariensis
Mate
Polyphenols
title_short Study of the participation of caffeine and polyphenols on the overall antioxidant activity of mate (Ilex paraguariensis)
title_full Study of the participation of caffeine and polyphenols on the overall antioxidant activity of mate (Ilex paraguariensis)
title_fullStr Study of the participation of caffeine and polyphenols on the overall antioxidant activity of mate (Ilex paraguariensis)
title_full_unstemmed Study of the participation of caffeine and polyphenols on the overall antioxidant activity of mate (Ilex paraguariensis)
title_sort Study of the participation of caffeine and polyphenols on the overall antioxidant activity of mate (Ilex paraguariensis)
dc.creator.none.fl_str_mv Anesini, Claudia Alejandra
Turner, Sebastian Ariel
Cogoi, Laura Carolina
Filip, Rosana
author Anesini, Claudia Alejandra
author_facet Anesini, Claudia Alejandra
Turner, Sebastian Ariel
Cogoi, Laura Carolina
Filip, Rosana
author_role author
author2 Turner, Sebastian Ariel
Cogoi, Laura Carolina
Filip, Rosana
author2_role author
author
author
dc.subject.none.fl_str_mv Antioxidant
Caffeine
Ilex paraguariensis
Mate
Polyphenols
topic Antioxidant
Caffeine
Ilex paraguariensis
Mate
Polyphenols
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The aim of this work was to investigate the participation of the main bioactive compounds (caffeine, caffeic acid derivatives and rutin) on the antioxidant activity (DPPH free radical scavenging activity and the prevention of lipid peroxidation) of the crude extracts of Ilex paraguariensis. Green and commercial products were used to prepare aqueous extracts. The main bioactive compounds were identified and quantified by HPLC-DAD. The antioxidant activities of the pure compounds in the concentrations present in the extracts were also analyzed. Results demonstrated that chlorogenic acid, caffeic acid and rutin contribute to the antioxidant activity. On the contrary, caffeine induced lipid peroxidation of linoleic acid acting as a pro-oxidant compound. The caffeine content in the green extracts was lower when compared to the commercial extracts. The antioxidant and pro-oxidant antagonistic effects of the compounds in the amounts present in the extracts resulted in higher antioxidant potency of the green extracts when compared to the commercial ones, as demonstrated by the EC 50 values and without affecting the maximum efficiency displayed by the extracts.
Fil: Anesini, Claudia Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
Fil: Turner, Sebastian Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
Fil: Cogoi, Laura Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
Fil: Filip, Rosana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
description The aim of this work was to investigate the participation of the main bioactive compounds (caffeine, caffeic acid derivatives and rutin) on the antioxidant activity (DPPH free radical scavenging activity and the prevention of lipid peroxidation) of the crude extracts of Ilex paraguariensis. Green and commercial products were used to prepare aqueous extracts. The main bioactive compounds were identified and quantified by HPLC-DAD. The antioxidant activities of the pure compounds in the concentrations present in the extracts were also analyzed. Results demonstrated that chlorogenic acid, caffeic acid and rutin contribute to the antioxidant activity. On the contrary, caffeine induced lipid peroxidation of linoleic acid acting as a pro-oxidant compound. The caffeine content in the green extracts was lower when compared to the commercial extracts. The antioxidant and pro-oxidant antagonistic effects of the compounds in the amounts present in the extracts resulted in higher antioxidant potency of the green extracts when compared to the commercial ones, as demonstrated by the EC 50 values and without affecting the maximum efficiency displayed by the extracts.
publishDate 2012
dc.date.none.fl_str_mv 2012-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/271120
Anesini, Claudia Alejandra; Turner, Sebastian Ariel; Cogoi, Laura Carolina; Filip, Rosana; Study of the participation of caffeine and polyphenols on the overall antioxidant activity of mate (Ilex paraguariensis); Elsevier Science; LWT - Food Science and Technology; 45; 2; 3-2012; 299-304
0023-6438
CONICET Digital
CONICET
url http://hdl.handle.net/11336/271120
identifier_str_mv Anesini, Claudia Alejandra; Turner, Sebastian Ariel; Cogoi, Laura Carolina; Filip, Rosana; Study of the participation of caffeine and polyphenols on the overall antioxidant activity of mate (Ilex paraguariensis); Elsevier Science; LWT - Food Science and Technology; 45; 2; 3-2012; 299-304
0023-6438
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S0023643811001988
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.lwt.2011.06.015
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844614159542517760
score 13.070432

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