Ancient proteins resolve the evolutionary history of Darwin's South American ungulates
- Autores
- Welker, Frido; Collins, Matthew J.; Thomas, Jessica A.; Wadsley, Marc; Brace, Selina; Cappellini, Enrico; Turvey, Samuel T.; Reguero, Marcelo Alfredo; Gelfo, Javier Nicolás; Kramarz, Alejandro Gustavo; Burger, Joachim; Thomas Oates, Jane; Ashford, David A.; Ashton, Peter D.; Rowsell, Keri; Porter, Duncan M.; Kessler, Benedikt; Fischer, Roman; Baessmann, Carsten; Kaspar, Stephanie; Olsen, Jesper V.; Kiley, Patrick; Elliott, James A.; Kelstrup, Christian D.; Mullin, Victoria; Hofreiter, Michael; Willerslev, Eske; Hublin, Jean Jacques; Orlando, Ludovic; Barnes, Ian; Macphee, Ross D. E.
- Año de publicación
- 2015
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- No large group of recently extinct placental mammals remains as evolutionarily cryptic as the approximately 280 genera grouped as South American native ungulates'. To Charles Darwin, who first collected their remains, they included perhaps the strangest animal[s] ever discovered'. Today, much like 180 years ago, it is no clearer whether they had one origin or several, arose before or after the Cretaceous/Palaeogene transition 66.2 million years ago, or are more likely to belong with the elephants and sirenians of superorder Afrotheria than with the euungulates (cattle, horses, and allies) of superorder Laurasiatheria. Morphology-based analyses have proved unconvincing because convergences are pervasive among unrelated ungulate-like placentals. Approaches using ancient DNA have also been unsuccessful, probably because of rapid DNA degradation in semitropical and temperate deposits. Here we apply proteomic analysis to screen bone samples of the Late Quaternary South American native ungulate taxa Toxodon (Notoungulata) and Macrauchenia (Litopterna) for phylogenetically informative protein sequences. For each ungulate, we obtain approximately 90% direct sequence coverage of type I collagen α1- and α2-chains, representing approximately 900 of 1,140 amino-acid residues for each subunit. A phylogeny is estimated from an alignment of these fossil sequences with collagen (I) gene transcripts from available mammalian genomes or mass spectrometrically derived sequence data obtained for this study. The resulting consensus tree agrees well with recent higher-level mammalian phylogenies. Toxodon and Macrauchenia form a monophyletic group whose sister taxon is not Afrotheria or any of its constituent clades as recently claimed, but instead crown Perissodactyla (horses, tapirs, and rhinoceroses). These results are consistent with the origin of at least some South American native ungulates from 'condylarths', a paraphyletic assembly of archaic placentals. With ongoing improvements in instrumentation and analytical procedures, proteomics may produce a revolution in systematics such as that achieved by genomics, but with the possibility of reaching much further back in time.
Fil: Welker, Frido. Institut Max Planck for Evolutionary Anthropology; Alemania. University of York; Reino Unido
Fil: Collins, Matthew J.. University of York; Reino Unido
Fil: Thomas, Jessica A.. University of York; Reino Unido
Fil: Wadsley, Marc. University of York; Reino Unido
Fil: Brace, Selina. Natural History Museum; Reino Unido
Fil: Cappellini, Enrico. Universidad de Copenhagen; Dinamarca. Natural History Museum of Denmark; Dinamarca
Fil: Turvey, Samuel T.. Zoological Society of London. Institute of Zoology; Reino Unido
Fil: Reguero, Marcelo Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Paleontología Vertebrados; Argentina
Fil: Gelfo, Javier Nicolás. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Paleontología Vertebrados; Argentina
Fil: Kramarz, Alejandro Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales “Bernardino Rivadavia”; Argentina
Fil: Burger, Joachim. Johhannes Gutenberg Universität. Institut für Anthropologie Anselm-Franz-von-Bentzel-Weg; Alemania
Fil: Thomas Oates, Jane. University of York; Reino Unido
Fil: Ashford, David A.. University of York; Reino Unido
Fil: Ashton, Peter D.. University of York; Reino Unido
Fil: Rowsell, Keri. University of York; Reino Unido
Fil: Porter, Duncan M.. Virginia Polytechnic Institute; Estados Unidos
Fil: Kessler, Benedikt. University of Oxford; Reino Unido
Fil: Fischer, Roman. University of Oxford; Reino Unido
Fil: Baessmann, Carsten. Bruker Daltonik GmbH. Applications Development; Alemania
Fil: Kaspar, Stephanie. Bruker Daltonik GmbH. Applications Development; Alemania
Fil: Olsen, Jesper V.. Universidad de Copenhagen; Dinamarca
Fil: Kiley, Patrick. University of Cambridge; Estados Unidos
Fil: Elliott, James A.. University of Cambridge; Estados Unidos
Fil: Kelstrup, Christian D.. Universidad de Copenhagen; Dinamarca
Fil: Mullin, Victoria. Trinity College Dublin. Smurfit Institute of Genetics; Irlanda
Fil: Hofreiter, Michael. University of York; Reino Unido. Universität Potsdam. Institut für Biochemie und Biologie; Alemania
Fil: Willerslev, Eske. Universidad de Copenhagen; Dinamarca. Natural History Museum of Denmark; Dinamarca
Fil: Hublin, Jean Jacques. Institut Max Planck for Evolutionary Anthropology; Alemania
Fil: Orlando, Ludovic. Universidad de Copenhagen; Dinamarca. Natural History Museum of Denmark; Dinamarca
Fil: Barnes, Ian. Natural History Museum; Reino Unido
Fil: Macphee, Ross D. E.. American Museum Of Natural History. New York; Estados Unidos - Materia
-
Ancient Proteins
Toxodon
Macrauchenia
Phylogeny - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/49922
Ver los metadatos del registro completo
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Ancient proteins resolve the evolutionary history of Darwin's South American ungulatesWelker, FridoCollins, Matthew J.Thomas, Jessica A.Wadsley, MarcBrace, SelinaCappellini, EnricoTurvey, Samuel T.Reguero, Marcelo AlfredoGelfo, Javier NicolásKramarz, Alejandro GustavoBurger, JoachimThomas Oates, JaneAshford, David A.Ashton, Peter D.Rowsell, KeriPorter, Duncan M.Kessler, BenediktFischer, RomanBaessmann, CarstenKaspar, StephanieOlsen, Jesper V.Kiley, PatrickElliott, James A.Kelstrup, Christian D.Mullin, VictoriaHofreiter, MichaelWillerslev, EskeHublin, Jean JacquesOrlando, LudovicBarnes, IanMacphee, Ross D. E.Ancient ProteinsToxodonMacraucheniaPhylogenyhttps://purl.org/becyt/ford/1.5https://purl.org/becyt/ford/1No large group of recently extinct placental mammals remains as evolutionarily cryptic as the approximately 280 genera grouped as South American native ungulates'. To Charles Darwin, who first collected their remains, they included perhaps the strangest animal[s] ever discovered'. Today, much like 180 years ago, it is no clearer whether they had one origin or several, arose before or after the Cretaceous/Palaeogene transition 66.2 million years ago, or are more likely to belong with the elephants and sirenians of superorder Afrotheria than with the euungulates (cattle, horses, and allies) of superorder Laurasiatheria. Morphology-based analyses have proved unconvincing because convergences are pervasive among unrelated ungulate-like placentals. Approaches using ancient DNA have also been unsuccessful, probably because of rapid DNA degradation in semitropical and temperate deposits. Here we apply proteomic analysis to screen bone samples of the Late Quaternary South American native ungulate taxa Toxodon (Notoungulata) and Macrauchenia (Litopterna) for phylogenetically informative protein sequences. For each ungulate, we obtain approximately 90% direct sequence coverage of type I collagen α1- and α2-chains, representing approximately 900 of 1,140 amino-acid residues for each subunit. A phylogeny is estimated from an alignment of these fossil sequences with collagen (I) gene transcripts from available mammalian genomes or mass spectrometrically derived sequence data obtained for this study. The resulting consensus tree agrees well with recent higher-level mammalian phylogenies. Toxodon and Macrauchenia form a monophyletic group whose sister taxon is not Afrotheria or any of its constituent clades as recently claimed, but instead crown Perissodactyla (horses, tapirs, and rhinoceroses). These results are consistent with the origin of at least some South American native ungulates from 'condylarths', a paraphyletic assembly of archaic placentals. With ongoing improvements in instrumentation and analytical procedures, proteomics may produce a revolution in systematics such as that achieved by genomics, but with the possibility of reaching much further back in time.Fil: Welker, Frido. Institut Max Planck for Evolutionary Anthropology; Alemania. University of York; Reino UnidoFil: Collins, Matthew J.. University of York; Reino UnidoFil: Thomas, Jessica A.. University of York; Reino UnidoFil: Wadsley, Marc. University of York; Reino UnidoFil: Brace, Selina. Natural History Museum; Reino UnidoFil: Cappellini, Enrico. Universidad de Copenhagen; Dinamarca. Natural History Museum of Denmark; DinamarcaFil: Turvey, Samuel T.. Zoological Society of London. Institute of Zoology; Reino UnidoFil: Reguero, Marcelo Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Paleontología Vertebrados; ArgentinaFil: Gelfo, Javier Nicolás. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Paleontología Vertebrados; ArgentinaFil: Kramarz, Alejandro Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales “Bernardino Rivadavia”; ArgentinaFil: Burger, Joachim. Johhannes Gutenberg Universität. Institut für Anthropologie Anselm-Franz-von-Bentzel-Weg; AlemaniaFil: Thomas Oates, Jane. University of York; Reino UnidoFil: Ashford, David A.. University of York; Reino UnidoFil: Ashton, Peter D.. University of York; Reino UnidoFil: Rowsell, Keri. University of York; Reino UnidoFil: Porter, Duncan M.. Virginia Polytechnic Institute; Estados UnidosFil: Kessler, Benedikt. University of Oxford; Reino UnidoFil: Fischer, Roman. University of Oxford; Reino UnidoFil: Baessmann, Carsten. Bruker Daltonik GmbH. Applications Development; AlemaniaFil: Kaspar, Stephanie. Bruker Daltonik GmbH. Applications Development; AlemaniaFil: Olsen, Jesper V.. Universidad de Copenhagen; DinamarcaFil: Kiley, Patrick. University of Cambridge; Estados UnidosFil: Elliott, James A.. University of Cambridge; Estados UnidosFil: Kelstrup, Christian D.. Universidad de Copenhagen; DinamarcaFil: Mullin, Victoria. Trinity College Dublin. Smurfit Institute of Genetics; IrlandaFil: Hofreiter, Michael. University of York; Reino Unido. Universität Potsdam. Institut für Biochemie und Biologie; AlemaniaFil: Willerslev, Eske. Universidad de Copenhagen; Dinamarca. Natural History Museum of Denmark; DinamarcaFil: Hublin, Jean Jacques. Institut Max Planck for Evolutionary Anthropology; AlemaniaFil: Orlando, Ludovic. Universidad de Copenhagen; Dinamarca. Natural History Museum of Denmark; DinamarcaFil: Barnes, Ian. Natural History Museum; Reino UnidoFil: Macphee, Ross D. E.. American Museum Of Natural History. New York; Estados UnidosNature Publishing Group2015-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/49922Welker, Frido; Collins, Matthew J.; Thomas, Jessica A.; Wadsley, Marc; Brace, Selina; et al.; Ancient proteins resolve the evolutionary history of Darwin's South American ungulates; Nature Publishing Group; Nature; 522; 7554; 6-2015; 81-840028-0836CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1038/nature14249info:eu-repo/semantics/altIdentifier/url/https://www.nature.com/articles/nature14249info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:47:41Zoai:ri.conicet.gov.ar:11336/49922instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:47:41.327CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Ancient proteins resolve the evolutionary history of Darwin's South American ungulates |
title |
Ancient proteins resolve the evolutionary history of Darwin's South American ungulates |
spellingShingle |
Ancient proteins resolve the evolutionary history of Darwin's South American ungulates Welker, Frido Ancient Proteins Toxodon Macrauchenia Phylogeny |
title_short |
Ancient proteins resolve the evolutionary history of Darwin's South American ungulates |
title_full |
Ancient proteins resolve the evolutionary history of Darwin's South American ungulates |
title_fullStr |
Ancient proteins resolve the evolutionary history of Darwin's South American ungulates |
title_full_unstemmed |
Ancient proteins resolve the evolutionary history of Darwin's South American ungulates |
title_sort |
Ancient proteins resolve the evolutionary history of Darwin's South American ungulates |
dc.creator.none.fl_str_mv |
Welker, Frido Collins, Matthew J. Thomas, Jessica A. Wadsley, Marc Brace, Selina Cappellini, Enrico Turvey, Samuel T. Reguero, Marcelo Alfredo Gelfo, Javier Nicolás Kramarz, Alejandro Gustavo Burger, Joachim Thomas Oates, Jane Ashford, David A. Ashton, Peter D. Rowsell, Keri Porter, Duncan M. Kessler, Benedikt Fischer, Roman Baessmann, Carsten Kaspar, Stephanie Olsen, Jesper V. Kiley, Patrick Elliott, James A. Kelstrup, Christian D. Mullin, Victoria Hofreiter, Michael Willerslev, Eske Hublin, Jean Jacques Orlando, Ludovic Barnes, Ian Macphee, Ross D. E. |
author |
Welker, Frido |
author_facet |
Welker, Frido Collins, Matthew J. Thomas, Jessica A. Wadsley, Marc Brace, Selina Cappellini, Enrico Turvey, Samuel T. Reguero, Marcelo Alfredo Gelfo, Javier Nicolás Kramarz, Alejandro Gustavo Burger, Joachim Thomas Oates, Jane Ashford, David A. Ashton, Peter D. Rowsell, Keri Porter, Duncan M. Kessler, Benedikt Fischer, Roman Baessmann, Carsten Kaspar, Stephanie Olsen, Jesper V. Kiley, Patrick Elliott, James A. Kelstrup, Christian D. Mullin, Victoria Hofreiter, Michael Willerslev, Eske Hublin, Jean Jacques Orlando, Ludovic Barnes, Ian Macphee, Ross D. E. |
author_role |
author |
author2 |
Collins, Matthew J. Thomas, Jessica A. Wadsley, Marc Brace, Selina Cappellini, Enrico Turvey, Samuel T. Reguero, Marcelo Alfredo Gelfo, Javier Nicolás Kramarz, Alejandro Gustavo Burger, Joachim Thomas Oates, Jane Ashford, David A. Ashton, Peter D. Rowsell, Keri Porter, Duncan M. Kessler, Benedikt Fischer, Roman Baessmann, Carsten Kaspar, Stephanie Olsen, Jesper V. Kiley, Patrick Elliott, James A. Kelstrup, Christian D. Mullin, Victoria Hofreiter, Michael Willerslev, Eske Hublin, Jean Jacques Orlando, Ludovic Barnes, Ian Macphee, Ross D. E. |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.subject.none.fl_str_mv |
Ancient Proteins Toxodon Macrauchenia Phylogeny |
topic |
Ancient Proteins Toxodon Macrauchenia Phylogeny |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.5 https://purl.org/becyt/ford/1 |
dc.description.none.fl_txt_mv |
No large group of recently extinct placental mammals remains as evolutionarily cryptic as the approximately 280 genera grouped as South American native ungulates'. To Charles Darwin, who first collected their remains, they included perhaps the strangest animal[s] ever discovered'. Today, much like 180 years ago, it is no clearer whether they had one origin or several, arose before or after the Cretaceous/Palaeogene transition 66.2 million years ago, or are more likely to belong with the elephants and sirenians of superorder Afrotheria than with the euungulates (cattle, horses, and allies) of superorder Laurasiatheria. Morphology-based analyses have proved unconvincing because convergences are pervasive among unrelated ungulate-like placentals. Approaches using ancient DNA have also been unsuccessful, probably because of rapid DNA degradation in semitropical and temperate deposits. Here we apply proteomic analysis to screen bone samples of the Late Quaternary South American native ungulate taxa Toxodon (Notoungulata) and Macrauchenia (Litopterna) for phylogenetically informative protein sequences. For each ungulate, we obtain approximately 90% direct sequence coverage of type I collagen α1- and α2-chains, representing approximately 900 of 1,140 amino-acid residues for each subunit. A phylogeny is estimated from an alignment of these fossil sequences with collagen (I) gene transcripts from available mammalian genomes or mass spectrometrically derived sequence data obtained for this study. The resulting consensus tree agrees well with recent higher-level mammalian phylogenies. Toxodon and Macrauchenia form a monophyletic group whose sister taxon is not Afrotheria or any of its constituent clades as recently claimed, but instead crown Perissodactyla (horses, tapirs, and rhinoceroses). These results are consistent with the origin of at least some South American native ungulates from 'condylarths', a paraphyletic assembly of archaic placentals. With ongoing improvements in instrumentation and analytical procedures, proteomics may produce a revolution in systematics such as that achieved by genomics, but with the possibility of reaching much further back in time. Fil: Welker, Frido. Institut Max Planck for Evolutionary Anthropology; Alemania. University of York; Reino Unido Fil: Collins, Matthew J.. University of York; Reino Unido Fil: Thomas, Jessica A.. University of York; Reino Unido Fil: Wadsley, Marc. University of York; Reino Unido Fil: Brace, Selina. Natural History Museum; Reino Unido Fil: Cappellini, Enrico. Universidad de Copenhagen; Dinamarca. Natural History Museum of Denmark; Dinamarca Fil: Turvey, Samuel T.. Zoological Society of London. Institute of Zoology; Reino Unido Fil: Reguero, Marcelo Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Paleontología Vertebrados; Argentina Fil: Gelfo, Javier Nicolás. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Paleontología Vertebrados; Argentina Fil: Kramarz, Alejandro Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales “Bernardino Rivadavia”; Argentina Fil: Burger, Joachim. Johhannes Gutenberg Universität. Institut für Anthropologie Anselm-Franz-von-Bentzel-Weg; Alemania Fil: Thomas Oates, Jane. University of York; Reino Unido Fil: Ashford, David A.. University of York; Reino Unido Fil: Ashton, Peter D.. University of York; Reino Unido Fil: Rowsell, Keri. University of York; Reino Unido Fil: Porter, Duncan M.. Virginia Polytechnic Institute; Estados Unidos Fil: Kessler, Benedikt. University of Oxford; Reino Unido Fil: Fischer, Roman. University of Oxford; Reino Unido Fil: Baessmann, Carsten. Bruker Daltonik GmbH. Applications Development; Alemania Fil: Kaspar, Stephanie. Bruker Daltonik GmbH. Applications Development; Alemania Fil: Olsen, Jesper V.. Universidad de Copenhagen; Dinamarca Fil: Kiley, Patrick. University of Cambridge; Estados Unidos Fil: Elliott, James A.. University of Cambridge; Estados Unidos Fil: Kelstrup, Christian D.. Universidad de Copenhagen; Dinamarca Fil: Mullin, Victoria. Trinity College Dublin. Smurfit Institute of Genetics; Irlanda Fil: Hofreiter, Michael. University of York; Reino Unido. Universität Potsdam. Institut für Biochemie und Biologie; Alemania Fil: Willerslev, Eske. Universidad de Copenhagen; Dinamarca. Natural History Museum of Denmark; Dinamarca Fil: Hublin, Jean Jacques. Institut Max Planck for Evolutionary Anthropology; Alemania Fil: Orlando, Ludovic. Universidad de Copenhagen; Dinamarca. Natural History Museum of Denmark; Dinamarca Fil: Barnes, Ian. Natural History Museum; Reino Unido Fil: Macphee, Ross D. E.. American Museum Of Natural History. New York; Estados Unidos |
description |
No large group of recently extinct placental mammals remains as evolutionarily cryptic as the approximately 280 genera grouped as South American native ungulates'. To Charles Darwin, who first collected their remains, they included perhaps the strangest animal[s] ever discovered'. Today, much like 180 years ago, it is no clearer whether they had one origin or several, arose before or after the Cretaceous/Palaeogene transition 66.2 million years ago, or are more likely to belong with the elephants and sirenians of superorder Afrotheria than with the euungulates (cattle, horses, and allies) of superorder Laurasiatheria. Morphology-based analyses have proved unconvincing because convergences are pervasive among unrelated ungulate-like placentals. Approaches using ancient DNA have also been unsuccessful, probably because of rapid DNA degradation in semitropical and temperate deposits. Here we apply proteomic analysis to screen bone samples of the Late Quaternary South American native ungulate taxa Toxodon (Notoungulata) and Macrauchenia (Litopterna) for phylogenetically informative protein sequences. For each ungulate, we obtain approximately 90% direct sequence coverage of type I collagen α1- and α2-chains, representing approximately 900 of 1,140 amino-acid residues for each subunit. A phylogeny is estimated from an alignment of these fossil sequences with collagen (I) gene transcripts from available mammalian genomes or mass spectrometrically derived sequence data obtained for this study. The resulting consensus tree agrees well with recent higher-level mammalian phylogenies. Toxodon and Macrauchenia form a monophyletic group whose sister taxon is not Afrotheria or any of its constituent clades as recently claimed, but instead crown Perissodactyla (horses, tapirs, and rhinoceroses). These results are consistent with the origin of at least some South American native ungulates from 'condylarths', a paraphyletic assembly of archaic placentals. With ongoing improvements in instrumentation and analytical procedures, proteomics may produce a revolution in systematics such as that achieved by genomics, but with the possibility of reaching much further back in time. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-06 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/49922 Welker, Frido; Collins, Matthew J.; Thomas, Jessica A.; Wadsley, Marc; Brace, Selina; et al.; Ancient proteins resolve the evolutionary history of Darwin's South American ungulates; Nature Publishing Group; Nature; 522; 7554; 6-2015; 81-84 0028-0836 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/49922 |
identifier_str_mv |
Welker, Frido; Collins, Matthew J.; Thomas, Jessica A.; Wadsley, Marc; Brace, Selina; et al.; Ancient proteins resolve the evolutionary history of Darwin's South American ungulates; Nature Publishing Group; Nature; 522; 7554; 6-2015; 81-84 0028-0836 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.1038/nature14249 info:eu-repo/semantics/altIdentifier/url/https://www.nature.com/articles/nature14249 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
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openAccess |
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https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
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application/pdf application/pdf application/pdf |
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Nature Publishing Group |
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Nature Publishing Group |
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Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
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dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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