Kinetics and binding properties of cloramphenicol imprinted polymers

Autores
Corton, Eduardo; García Calzón, J. A.; Díaz García, M. E.
Año de publicación
2007
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Molecularly imprinted polymers (MIPs) are easily obtained by a non-covalent approach through the copolymerisation of suitable functional monomers and cross-linkers in the presence of the print molecule. Removal of the template leaves a polymer that selectively recognises it. However, experimental data have demonstrated that non-covalent molecularly imprinted polymers exhibit a heterogeneous binding sites distribution. In this work, two different imprinted polymers for chloramphenicol (CAP), obtained using different template concentrations, were evaluated for their kinetics and affinity binding properties against CAP in a batch approach. Experimental binding isotherms were fitted to Langmuir, Freundlich and Langmuir-Freundlich isotherms and the affinity distribution corresponding to the Freundlich isotherm was used to extract binding parameters. Parallel studies were performed for the binding of chloramphenicol diacetate to the CAP-imprinted polymers.
Fil: Corton, Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; Argentina
Fil: García Calzón, J. A.. Universidad de Oviedo; España
Fil: Díaz García, M. E.. Universidad de Oviedo; España
Materia
ADSORPTION
PHARMACEUTICALS
POLYMERS AND ORGANICS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/95886
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Kinetics and binding properties of cloramphenicol imprinted polymersCorton, EduardoGarcía Calzón, J. A.Díaz García, M. E.ADSORPTIONPHARMACEUTICALSPOLYMERS AND ORGANICShttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Molecularly imprinted polymers (MIPs) are easily obtained by a non-covalent approach through the copolymerisation of suitable functional monomers and cross-linkers in the presence of the print molecule. Removal of the template leaves a polymer that selectively recognises it. However, experimental data have demonstrated that non-covalent molecularly imprinted polymers exhibit a heterogeneous binding sites distribution. In this work, two different imprinted polymers for chloramphenicol (CAP), obtained using different template concentrations, were evaluated for their kinetics and affinity binding properties against CAP in a batch approach. Experimental binding isotherms were fitted to Langmuir, Freundlich and Langmuir-Freundlich isotherms and the affinity distribution corresponding to the Freundlich isotherm was used to extract binding parameters. Parallel studies were performed for the binding of chloramphenicol diacetate to the CAP-imprinted polymers.Fil: Corton, Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; ArgentinaFil: García Calzón, J. A.. Universidad de Oviedo; EspañaFil: Díaz García, M. E.. Universidad de Oviedo; EspañaElsevier Science2007-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/95886Corton, Eduardo; García Calzón, J. A.; Díaz García, M. E.; Kinetics and binding properties of cloramphenicol imprinted polymers; Elsevier Science; Journal of Non-crystalline Solids; 353; 8-10; 4-2007; 974-9800022-3093CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.jnoncrysol.2006.12.066info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0022309307000531info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:41:32Zoai:ri.conicet.gov.ar:11336/95886instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:41:33.194CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Kinetics and binding properties of cloramphenicol imprinted polymers
title Kinetics and binding properties of cloramphenicol imprinted polymers
spellingShingle Kinetics and binding properties of cloramphenicol imprinted polymers
Corton, Eduardo
ADSORPTION
PHARMACEUTICALS
POLYMERS AND ORGANICS
title_short Kinetics and binding properties of cloramphenicol imprinted polymers
title_full Kinetics and binding properties of cloramphenicol imprinted polymers
title_fullStr Kinetics and binding properties of cloramphenicol imprinted polymers
title_full_unstemmed Kinetics and binding properties of cloramphenicol imprinted polymers
title_sort Kinetics and binding properties of cloramphenicol imprinted polymers
dc.creator.none.fl_str_mv Corton, Eduardo
García Calzón, J. A.
Díaz García, M. E.
author Corton, Eduardo
author_facet Corton, Eduardo
García Calzón, J. A.
Díaz García, M. E.
author_role author
author2 García Calzón, J. A.
Díaz García, M. E.
author2_role author
author
dc.subject.none.fl_str_mv ADSORPTION
PHARMACEUTICALS
POLYMERS AND ORGANICS
topic ADSORPTION
PHARMACEUTICALS
POLYMERS AND ORGANICS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Molecularly imprinted polymers (MIPs) are easily obtained by a non-covalent approach through the copolymerisation of suitable functional monomers and cross-linkers in the presence of the print molecule. Removal of the template leaves a polymer that selectively recognises it. However, experimental data have demonstrated that non-covalent molecularly imprinted polymers exhibit a heterogeneous binding sites distribution. In this work, two different imprinted polymers for chloramphenicol (CAP), obtained using different template concentrations, were evaluated for their kinetics and affinity binding properties against CAP in a batch approach. Experimental binding isotherms were fitted to Langmuir, Freundlich and Langmuir-Freundlich isotherms and the affinity distribution corresponding to the Freundlich isotherm was used to extract binding parameters. Parallel studies were performed for the binding of chloramphenicol diacetate to the CAP-imprinted polymers.
Fil: Corton, Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; Argentina
Fil: García Calzón, J. A.. Universidad de Oviedo; España
Fil: Díaz García, M. E.. Universidad de Oviedo; España
description Molecularly imprinted polymers (MIPs) are easily obtained by a non-covalent approach through the copolymerisation of suitable functional monomers and cross-linkers in the presence of the print molecule. Removal of the template leaves a polymer that selectively recognises it. However, experimental data have demonstrated that non-covalent molecularly imprinted polymers exhibit a heterogeneous binding sites distribution. In this work, two different imprinted polymers for chloramphenicol (CAP), obtained using different template concentrations, were evaluated for their kinetics and affinity binding properties against CAP in a batch approach. Experimental binding isotherms were fitted to Langmuir, Freundlich and Langmuir-Freundlich isotherms and the affinity distribution corresponding to the Freundlich isotherm was used to extract binding parameters. Parallel studies were performed for the binding of chloramphenicol diacetate to the CAP-imprinted polymers.
publishDate 2007
dc.date.none.fl_str_mv 2007-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/95886
Corton, Eduardo; García Calzón, J. A.; Díaz García, M. E.; Kinetics and binding properties of cloramphenicol imprinted polymers; Elsevier Science; Journal of Non-crystalline Solids; 353; 8-10; 4-2007; 974-980
0022-3093
CONICET Digital
CONICET
url http://hdl.handle.net/11336/95886
identifier_str_mv Corton, Eduardo; García Calzón, J. A.; Díaz García, M. E.; Kinetics and binding properties of cloramphenicol imprinted polymers; Elsevier Science; Journal of Non-crystalline Solids; 353; 8-10; 4-2007; 974-980
0022-3093
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jnoncrysol.2006.12.066
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0022309307000531
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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