An alternative model for the early peopling of Southern South America revealed by analyses of three mitochondrial DNA haplogroups

Autores
de Saint Pierre, Michelle; Bravi, Claudio Marcelo; Motti, Josefina María Brenda; Fuku, Noriyuku; Tanaka, Masashi; Llop, Elena; Bonatto, Sandro L.; Moraga, Mauricio
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
After several years of research, there is now a consensus that America was populated from Asia through Beringia, probably at the end of the Pleistocene. But many details such as the timing, route(s), and origin of the first settlers remain uncertain. In the last decade genetic evidence has taken on a major role in elucidating the peopling of the Americas. To study the early peopling of South America, we sequenced the control region of mitochondrial DNA from 300 individuals belonging to indigenous populations of Chile and Argentina, and also obtained seven complete mitochondrial DNA sequences. We identified two novel mtDNA monophyletic clades, preliminarily designated B2l and C1b13, which together with the recently described D1g sub-haplogroup have locally high frequencies and are basically restricted to populations from the extreme south of South America. The estimated ages of D1g and B2l, about ∼ 15,000 years BP, together with their similar population dynamics and the high haplotype diversity shown by the networks, suggests that they probably appeared soon after the arrival of the first settlers and agrees with the dating of the earliest archaeological sites in South America (Monte Verde, Chile, 14,500 BP). One further sub-haplogroup, D4h3a5, appears to be restricted to Fuegian-Patagonian populations and reinforces our hypothesis of the continuity of the current Patagonian populations with the initial founders. Our results indicate that the extant native populations inhabiting South Chile and Argentina are a group which had a common origin, and suggest a population break between the extreme south of South America and the more northern part of the continent. Thus the early colonization process was not just an expansion from north to south, but also included movements across the Andes.
Fil: de Saint Pierre, Michelle. Universidad de Chile; Chile
Fil: Bravi, Claudio Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina
Fil: Motti, Josefina María Brenda. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina
Fil: Fuku, Noriyuku. Tokyo Metropolitan Institute of Gerontology; Japón
Fil: Tanaka, Masashi. Tokyo Metropolitan Institute Of Gerontology; Japón
Fil: Llop, Elena. Universidad de Chile; Chile
Fil: Bonatto, Sandro L.. Pontificia Universidade Católica do Rio Grande do Sul; Brasil
Fil: Moraga, Mauricio. Universidad de Chile; Chile
Materia
MITOCHONDRIAL DNA
NATIVE AMERICANS
HAPLOGROUP
HAPLOTYPES
PATAGONIA
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/68114
Acceder
id CONICETDig_dc9b4373905435dd70f7313f42578650
oai_identifier_str oai:ri.conicet.gov.ar:11336/68114
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling An alternative model for the early peopling of Southern South America revealed by analyses of three mitochondrial DNA haplogroupsde Saint Pierre, MichelleBravi, Claudio MarceloMotti, Josefina María BrendaFuku, NoriyukuTanaka, MasashiLlop, ElenaBonatto, Sandro L.Moraga, MauricioMITOCHONDRIAL DNANATIVE AMERICANSHAPLOGROUPHAPLOTYPESPATAGONIAhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1After several years of research, there is now a consensus that America was populated from Asia through Beringia, probably at the end of the Pleistocene. But many details such as the timing, route(s), and origin of the first settlers remain uncertain. In the last decade genetic evidence has taken on a major role in elucidating the peopling of the Americas. To study the early peopling of South America, we sequenced the control region of mitochondrial DNA from 300 individuals belonging to indigenous populations of Chile and Argentina, and also obtained seven complete mitochondrial DNA sequences. We identified two novel mtDNA monophyletic clades, preliminarily designated B2l and C1b13, which together with the recently described D1g sub-haplogroup have locally high frequencies and are basically restricted to populations from the extreme south of South America. The estimated ages of D1g and B2l, about ∼ 15,000 years BP, together with their similar population dynamics and the high haplotype diversity shown by the networks, suggests that they probably appeared soon after the arrival of the first settlers and agrees with the dating of the earliest archaeological sites in South America (Monte Verde, Chile, 14,500 BP). One further sub-haplogroup, D4h3a5, appears to be restricted to Fuegian-Patagonian populations and reinforces our hypothesis of the continuity of the current Patagonian populations with the initial founders. Our results indicate that the extant native populations inhabiting South Chile and Argentina are a group which had a common origin, and suggest a population break between the extreme south of South America and the more northern part of the continent. Thus the early colonization process was not just an expansion from north to south, but also included movements across the Andes.Fil: de Saint Pierre, Michelle. Universidad de Chile; ChileFil: Bravi, Claudio Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; ArgentinaFil: Motti, Josefina María Brenda. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; ArgentinaFil: Fuku, Noriyuku. Tokyo Metropolitan Institute of Gerontology; JapónFil: Tanaka, Masashi. Tokyo Metropolitan Institute Of Gerontology; JapónFil: Llop, Elena. Universidad de Chile; ChileFil: Bonatto, Sandro L.. Pontificia Universidade Católica do Rio Grande do Sul; BrasilFil: Moraga, Mauricio. Universidad de Chile; ChilePublic Library of Science2012-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/68114de Saint Pierre, Michelle; Bravi, Claudio Marcelo; Motti, Josefina María Brenda; Fuku, Noriyuku; Tanaka, Masashi; et al.; An alternative model for the early peopling of Southern South America revealed by analyses of three mitochondrial DNA haplogroups; Public Library of Science; Plos One; 7; 9; 9-2012; 43486-434981932-6203CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0043486info:eu-repo/semantics/altIdentifier/doi/10.1371/journal.pone.0043486info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:53:07Zoai:ri.conicet.gov.ar:11336/68114instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:53:07.879CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv An alternative model for the early peopling of Southern South America revealed by analyses of three mitochondrial DNA haplogroups
title An alternative model for the early peopling of Southern South America revealed by analyses of three mitochondrial DNA haplogroups
spellingShingle An alternative model for the early peopling of Southern South America revealed by analyses of three mitochondrial DNA haplogroups
de Saint Pierre, Michelle
MITOCHONDRIAL DNA
NATIVE AMERICANS
HAPLOGROUP
HAPLOTYPES
PATAGONIA
title_short An alternative model for the early peopling of Southern South America revealed by analyses of three mitochondrial DNA haplogroups
title_full An alternative model for the early peopling of Southern South America revealed by analyses of three mitochondrial DNA haplogroups
title_fullStr An alternative model for the early peopling of Southern South America revealed by analyses of three mitochondrial DNA haplogroups
title_full_unstemmed An alternative model for the early peopling of Southern South America revealed by analyses of three mitochondrial DNA haplogroups
title_sort An alternative model for the early peopling of Southern South America revealed by analyses of three mitochondrial DNA haplogroups
dc.creator.none.fl_str_mv de Saint Pierre, Michelle
Bravi, Claudio Marcelo
Motti, Josefina María Brenda
Fuku, Noriyuku
Tanaka, Masashi
Llop, Elena
Bonatto, Sandro L.
Moraga, Mauricio
author de Saint Pierre, Michelle
author_facet de Saint Pierre, Michelle
Bravi, Claudio Marcelo
Motti, Josefina María Brenda
Fuku, Noriyuku
Tanaka, Masashi
Llop, Elena
Bonatto, Sandro L.
Moraga, Mauricio
author_role author
author2 Bravi, Claudio Marcelo
Motti, Josefina María Brenda
Fuku, Noriyuku
Tanaka, Masashi
Llop, Elena
Bonatto, Sandro L.
Moraga, Mauricio
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv MITOCHONDRIAL DNA
NATIVE AMERICANS
HAPLOGROUP
HAPLOTYPES
PATAGONIA
topic MITOCHONDRIAL DNA
NATIVE AMERICANS
HAPLOGROUP
HAPLOTYPES
PATAGONIA
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv After several years of research, there is now a consensus that America was populated from Asia through Beringia, probably at the end of the Pleistocene. But many details such as the timing, route(s), and origin of the first settlers remain uncertain. In the last decade genetic evidence has taken on a major role in elucidating the peopling of the Americas. To study the early peopling of South America, we sequenced the control region of mitochondrial DNA from 300 individuals belonging to indigenous populations of Chile and Argentina, and also obtained seven complete mitochondrial DNA sequences. We identified two novel mtDNA monophyletic clades, preliminarily designated B2l and C1b13, which together with the recently described D1g sub-haplogroup have locally high frequencies and are basically restricted to populations from the extreme south of South America. The estimated ages of D1g and B2l, about ∼ 15,000 years BP, together with their similar population dynamics and the high haplotype diversity shown by the networks, suggests that they probably appeared soon after the arrival of the first settlers and agrees with the dating of the earliest archaeological sites in South America (Monte Verde, Chile, 14,500 BP). One further sub-haplogroup, D4h3a5, appears to be restricted to Fuegian-Patagonian populations and reinforces our hypothesis of the continuity of the current Patagonian populations with the initial founders. Our results indicate that the extant native populations inhabiting South Chile and Argentina are a group which had a common origin, and suggest a population break between the extreme south of South America and the more northern part of the continent. Thus the early colonization process was not just an expansion from north to south, but also included movements across the Andes.
Fil: de Saint Pierre, Michelle. Universidad de Chile; Chile
Fil: Bravi, Claudio Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina
Fil: Motti, Josefina María Brenda. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina
Fil: Fuku, Noriyuku. Tokyo Metropolitan Institute of Gerontology; Japón
Fil: Tanaka, Masashi. Tokyo Metropolitan Institute Of Gerontology; Japón
Fil: Llop, Elena. Universidad de Chile; Chile
Fil: Bonatto, Sandro L.. Pontificia Universidade Católica do Rio Grande do Sul; Brasil
Fil: Moraga, Mauricio. Universidad de Chile; Chile
description After several years of research, there is now a consensus that America was populated from Asia through Beringia, probably at the end of the Pleistocene. But many details such as the timing, route(s), and origin of the first settlers remain uncertain. In the last decade genetic evidence has taken on a major role in elucidating the peopling of the Americas. To study the early peopling of South America, we sequenced the control region of mitochondrial DNA from 300 individuals belonging to indigenous populations of Chile and Argentina, and also obtained seven complete mitochondrial DNA sequences. We identified two novel mtDNA monophyletic clades, preliminarily designated B2l and C1b13, which together with the recently described D1g sub-haplogroup have locally high frequencies and are basically restricted to populations from the extreme south of South America. The estimated ages of D1g and B2l, about ∼ 15,000 years BP, together with their similar population dynamics and the high haplotype diversity shown by the networks, suggests that they probably appeared soon after the arrival of the first settlers and agrees with the dating of the earliest archaeological sites in South America (Monte Verde, Chile, 14,500 BP). One further sub-haplogroup, D4h3a5, appears to be restricted to Fuegian-Patagonian populations and reinforces our hypothesis of the continuity of the current Patagonian populations with the initial founders. Our results indicate that the extant native populations inhabiting South Chile and Argentina are a group which had a common origin, and suggest a population break between the extreme south of South America and the more northern part of the continent. Thus the early colonization process was not just an expansion from north to south, but also included movements across the Andes.
publishDate 2012
dc.date.none.fl_str_mv 2012-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/68114
de Saint Pierre, Michelle; Bravi, Claudio Marcelo; Motti, Josefina María Brenda; Fuku, Noriyuku; Tanaka, Masashi; et al.; An alternative model for the early peopling of Southern South America revealed by analyses of three mitochondrial DNA haplogroups; Public Library of Science; Plos One; 7; 9; 9-2012; 43486-43498
1932-6203
CONICET Digital
CONICET
url http://hdl.handle.net/11336/68114
identifier_str_mv de Saint Pierre, Michelle; Bravi, Claudio Marcelo; Motti, Josefina María Brenda; Fuku, Noriyuku; Tanaka, Masashi; et al.; An alternative model for the early peopling of Southern South America revealed by analyses of three mitochondrial DNA haplogroups; Public Library of Science; Plos One; 7; 9; 9-2012; 43486-43498
1932-6203
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0043486
info:eu-repo/semantics/altIdentifier/doi/10.1371/journal.pone.0043486
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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