Bacterial nano cellulose as non-active pharmaceutical ingredient: Advances and perspectives

Autores
González, Exequiel Elías; Cerúsico, Nicolás Abel; Moreno, María Julieta; Sesto Cabral, María Eugenia
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Nano Cellulose is commonly produced by the top-down enzymatic, mechanical and/or chemical treatments. In contrast, Bacterial Nano Cellulose (BNC) can be obtained by a bottom-up approach, where is biosynthesized from glucose using the direct action of specific bacterial strains. BNC impart attractive combinations of biologic and physicochemical characteristics such as biocompatibility, biodegradability, light weight, sustainability, and improved mechanical properties. The trend towards environmental sustainability and development of renewable resources has significantly increased interest. A critical aspect in BNC production is to identify a low-cost culture medium that can improve the yield of BNC and can be used as an economically viable solution for application in a range of fields. There is an immense perspective of BNC in health care as well as drug applications. Potential uses include barrier films, antimicrobial films, pharmaceuticals and drug delivery systems. Even though BNC has been demonstrated as nongenotoxic and noncytotoxic, further studies are required to completely address such issue. Key aspects for future development include the design of BNC for specific user requirements, the reduction of production costs, and the customization/functionalization using post production steps and different types of compounding/processing.
Fil: González, Exequiel Elías. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
Fil: Cerúsico, Nicolás Abel. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
Fil: Moreno, María Julieta. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
Fil: Sesto Cabral, María Eugenia. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
Materia
BACTERIAL NANO CELLULOSE
PHARMACEUTICAL BIOTECHNOLOGY
PHARMACEUTICS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/148421
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Bacterial nano cellulose as non-active pharmaceutical ingredient: Advances and perspectivesGonzález, Exequiel ElíasCerúsico, Nicolás AbelMoreno, María JulietaSesto Cabral, María EugeniaBACTERIAL NANO CELLULOSEPHARMACEUTICAL BIOTECHNOLOGYPHARMACEUTICShttps://purl.org/becyt/ford/3.4https://purl.org/becyt/ford/3Nano Cellulose is commonly produced by the top-down enzymatic, mechanical and/or chemical treatments. In contrast, Bacterial Nano Cellulose (BNC) can be obtained by a bottom-up approach, where is biosynthesized from glucose using the direct action of specific bacterial strains. BNC impart attractive combinations of biologic and physicochemical characteristics such as biocompatibility, biodegradability, light weight, sustainability, and improved mechanical properties. The trend towards environmental sustainability and development of renewable resources has significantly increased interest. A critical aspect in BNC production is to identify a low-cost culture medium that can improve the yield of BNC and can be used as an economically viable solution for application in a range of fields. There is an immense perspective of BNC in health care as well as drug applications. Potential uses include barrier films, antimicrobial films, pharmaceuticals and drug delivery systems. Even though BNC has been demonstrated as nongenotoxic and noncytotoxic, further studies are required to completely address such issue. Key aspects for future development include the design of BNC for specific user requirements, the reduction of production costs, and the customization/functionalization using post production steps and different types of compounding/processing.Fil: González, Exequiel Elías. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; ArgentinaFil: Cerúsico, Nicolás Abel. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; ArgentinaFil: Moreno, María Julieta. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; ArgentinaFil: Sesto Cabral, María Eugenia. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; ArgentinaMedCrave2018-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/148421González, Exequiel Elías; Cerúsico, Nicolás Abel; Moreno, María Julieta; Sesto Cabral, María Eugenia; Bacterial nano cellulose as non-active pharmaceutical ingredient: Advances and perspectives; MedCrave; Drug Design Development and Therapy; 2; 6; 11-2018; 230-2331177-88812575-9094CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://medcraveonline.com/MOJDDT/bacterial-nano-cellulose-as-non-active-pharmaceutical-ingredient-advances-and-perspectives.htmlinfo:eu-repo/semantics/altIdentifier/doi/10.15406/mojddt.2018.02.00067info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-17T10:48:25Zoai:ri.conicet.gov.ar:11336/148421instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-17 10:48:25.716CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Bacterial nano cellulose as non-active pharmaceutical ingredient: Advances and perspectives
title Bacterial nano cellulose as non-active pharmaceutical ingredient: Advances and perspectives
spellingShingle Bacterial nano cellulose as non-active pharmaceutical ingredient: Advances and perspectives
González, Exequiel Elías
BACTERIAL NANO CELLULOSE
PHARMACEUTICAL BIOTECHNOLOGY
PHARMACEUTICS
title_short Bacterial nano cellulose as non-active pharmaceutical ingredient: Advances and perspectives
title_full Bacterial nano cellulose as non-active pharmaceutical ingredient: Advances and perspectives
title_fullStr Bacterial nano cellulose as non-active pharmaceutical ingredient: Advances and perspectives
title_full_unstemmed Bacterial nano cellulose as non-active pharmaceutical ingredient: Advances and perspectives
title_sort Bacterial nano cellulose as non-active pharmaceutical ingredient: Advances and perspectives
dc.creator.none.fl_str_mv González, Exequiel Elías
Cerúsico, Nicolás Abel
Moreno, María Julieta
Sesto Cabral, María Eugenia
author González, Exequiel Elías
author_facet González, Exequiel Elías
Cerúsico, Nicolás Abel
Moreno, María Julieta
Sesto Cabral, María Eugenia
author_role author
author2 Cerúsico, Nicolás Abel
Moreno, María Julieta
Sesto Cabral, María Eugenia
author2_role author
author
author
dc.subject.none.fl_str_mv BACTERIAL NANO CELLULOSE
PHARMACEUTICAL BIOTECHNOLOGY
PHARMACEUTICS
topic BACTERIAL NANO CELLULOSE
PHARMACEUTICAL BIOTECHNOLOGY
PHARMACEUTICS
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.4
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Nano Cellulose is commonly produced by the top-down enzymatic, mechanical and/or chemical treatments. In contrast, Bacterial Nano Cellulose (BNC) can be obtained by a bottom-up approach, where is biosynthesized from glucose using the direct action of specific bacterial strains. BNC impart attractive combinations of biologic and physicochemical characteristics such as biocompatibility, biodegradability, light weight, sustainability, and improved mechanical properties. The trend towards environmental sustainability and development of renewable resources has significantly increased interest. A critical aspect in BNC production is to identify a low-cost culture medium that can improve the yield of BNC and can be used as an economically viable solution for application in a range of fields. There is an immense perspective of BNC in health care as well as drug applications. Potential uses include barrier films, antimicrobial films, pharmaceuticals and drug delivery systems. Even though BNC has been demonstrated as nongenotoxic and noncytotoxic, further studies are required to completely address such issue. Key aspects for future development include the design of BNC for specific user requirements, the reduction of production costs, and the customization/functionalization using post production steps and different types of compounding/processing.
Fil: González, Exequiel Elías. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
Fil: Cerúsico, Nicolás Abel. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
Fil: Moreno, María Julieta. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
Fil: Sesto Cabral, María Eugenia. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina
description Nano Cellulose is commonly produced by the top-down enzymatic, mechanical and/or chemical treatments. In contrast, Bacterial Nano Cellulose (BNC) can be obtained by a bottom-up approach, where is biosynthesized from glucose using the direct action of specific bacterial strains. BNC impart attractive combinations of biologic and physicochemical characteristics such as biocompatibility, biodegradability, light weight, sustainability, and improved mechanical properties. The trend towards environmental sustainability and development of renewable resources has significantly increased interest. A critical aspect in BNC production is to identify a low-cost culture medium that can improve the yield of BNC and can be used as an economically viable solution for application in a range of fields. There is an immense perspective of BNC in health care as well as drug applications. Potential uses include barrier films, antimicrobial films, pharmaceuticals and drug delivery systems. Even though BNC has been demonstrated as nongenotoxic and noncytotoxic, further studies are required to completely address such issue. Key aspects for future development include the design of BNC for specific user requirements, the reduction of production costs, and the customization/functionalization using post production steps and different types of compounding/processing.
publishDate 2018
dc.date.none.fl_str_mv 2018-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/148421
González, Exequiel Elías; Cerúsico, Nicolás Abel; Moreno, María Julieta; Sesto Cabral, María Eugenia; Bacterial nano cellulose as non-active pharmaceutical ingredient: Advances and perspectives; MedCrave; Drug Design Development and Therapy; 2; 6; 11-2018; 230-233
1177-8881
2575-9094
CONICET Digital
CONICET
url http://hdl.handle.net/11336/148421
identifier_str_mv González, Exequiel Elías; Cerúsico, Nicolás Abel; Moreno, María Julieta; Sesto Cabral, María Eugenia; Bacterial nano cellulose as non-active pharmaceutical ingredient: Advances and perspectives; MedCrave; Drug Design Development and Therapy; 2; 6; 11-2018; 230-233
1177-8881
2575-9094
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://medcraveonline.com/MOJDDT/bacterial-nano-cellulose-as-non-active-pharmaceutical-ingredient-advances-and-perspectives.html
info:eu-repo/semantics/altIdentifier/doi/10.15406/mojddt.2018.02.00067
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv MedCrave
publisher.none.fl_str_mv MedCrave
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.001348

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