Antibacterial and cytotoxic activities of Acacia aroma extracts

Autores
Mattana, Claudia Maricel; Satorres, Sara Elena; Escobar, Franco Matias; Sabini, Maria Carola; Sabini, Liliana Ines; Fusco, María del Rosario; Alcaráz, Lucia Esther
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Acacia aroma, native plant from San Luis, Argentina, is used commonly like antiseptic and healing of wounds. The present study was conducted to investigate the in vitro antibacterial activity of extracts of A. aroma and its toxicity on Vero cell. The bacterial strains used were Staphylococcus aureus ATCC 43300, S. aureus ATCC 35556, Listeria monocytogenes CLIP 74910 and L. monocytogenes CLIP 74904. The minimal inhibitory concentration (MICs) and minimal bactericidal concentration (CBMs) was determined and tested at concentration ranges from 5000 to 78μg/mL. On the other hand, the cytotoxic activity on Vero cells was assayed by MTT method. The MIC values of EE and HAE against S. aureus was 156μg/mL and 625μg/mL respectively. MBC values were one or two fold higher than the corresponding MIC values in both extracts. Listeria strains studied gave MICs and MBCs values of 78μg/mL and 312μg/mLl respectively for EE, while HAE showed less antibacterial activity against this strain (MIC=1250μg/mL and MBC=5000μg/mL). The CC50 was 658μg/mL for EE and 1020μg/mL for HAE. The extracts of A. aroma tested in vitro showed inhibitory activity against Staphylococcus and Listeria. These results allow validating the external use of this plant.
Fil: Mattana, Claudia Maricel. Universidad Nacional de San Luis; Argentina
Fil: Satorres, Sara Elena. Universidad Nacional de San Luis; Argentina
Fil: Escobar, Franco Matias. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto; Argentina
Fil: Sabini, Maria Carola. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto; Argentina
Fil: Sabini, Liliana Ines. Universidad Nacional de Río Cuarto; Argentina
Fil: Fusco, María del Rosario. Universidad Nacional de San Luis; Argentina
Fil: Alcaráz, Lucia Esther. Universidad Nacional de San Luis; Argentina
Materia
ACACIA AROMA
ANTIBACTERIAL ACTIVITY
CYTOTOXICITY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/282013
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/282013
network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Antibacterial and cytotoxic activities of Acacia aroma extractsMattana, Claudia MaricelSatorres, Sara ElenaEscobar, Franco MatiasSabini, Maria CarolaSabini, Liliana InesFusco, María del RosarioAlcaráz, Lucia EstherACACIA AROMAANTIBACTERIAL ACTIVITYCYTOTOXICITYhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Acacia aroma, native plant from San Luis, Argentina, is used commonly like antiseptic and healing of wounds. The present study was conducted to investigate the in vitro antibacterial activity of extracts of A. aroma and its toxicity on Vero cell. The bacterial strains used were Staphylococcus aureus ATCC 43300, S. aureus ATCC 35556, Listeria monocytogenes CLIP 74910 and L. monocytogenes CLIP 74904. The minimal inhibitory concentration (MICs) and minimal bactericidal concentration (CBMs) was determined and tested at concentration ranges from 5000 to 78μg/mL. On the other hand, the cytotoxic activity on Vero cells was assayed by MTT method. The MIC values of EE and HAE against S. aureus was 156μg/mL and 625μg/mL respectively. MBC values were one or two fold higher than the corresponding MIC values in both extracts. Listeria strains studied gave MICs and MBCs values of 78μg/mL and 312μg/mLl respectively for EE, while HAE showed less antibacterial activity against this strain (MIC=1250μg/mL and MBC=5000μg/mL). The CC50 was 658μg/mL for EE and 1020μg/mL for HAE. The extracts of A. aroma tested in vitro showed inhibitory activity against Staphylococcus and Listeria. These results allow validating the external use of this plant.Fil: Mattana, Claudia Maricel. Universidad Nacional de San Luis; ArgentinaFil: Satorres, Sara Elena. Universidad Nacional de San Luis; ArgentinaFil: Escobar, Franco Matias. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto; ArgentinaFil: Sabini, Maria Carola. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto; ArgentinaFil: Sabini, Liliana Ines. Universidad Nacional de Río Cuarto; ArgentinaFil: Fusco, María del Rosario. Universidad Nacional de San Luis; ArgentinaFil: Alcaráz, Lucia Esther. Universidad Nacional de San Luis; ArgentinaUniversidad de Emiratos Árabes Unidos2012-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/282013Mattana, Claudia Maricel; Satorres, Sara Elena; Escobar, Franco Matias; Sabini, Maria Carola; Sabini, Liliana Ines; et al.; Antibacterial and cytotoxic activities of Acacia aroma extracts; Universidad de Emiratos Árabes Unidos; Emirates Journal of Food and Agriculture; 24; 4; 6-2012; 308-3132079-052x2079-0538CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://ejfa.me/index.php/journal/article/view/888info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2026-03-11T12:06:29Zoai:ri.conicet.gov.ar:11336/282013instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982026-03-11 12:06:29.493CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Antibacterial and cytotoxic activities of Acacia aroma extracts
title Antibacterial and cytotoxic activities of Acacia aroma extracts
spellingShingle Antibacterial and cytotoxic activities of Acacia aroma extracts
Mattana, Claudia Maricel
ACACIA AROMA
ANTIBACTERIAL ACTIVITY
CYTOTOXICITY
title_short Antibacterial and cytotoxic activities of Acacia aroma extracts
title_full Antibacterial and cytotoxic activities of Acacia aroma extracts
title_fullStr Antibacterial and cytotoxic activities of Acacia aroma extracts
title_full_unstemmed Antibacterial and cytotoxic activities of Acacia aroma extracts
title_sort Antibacterial and cytotoxic activities of Acacia aroma extracts
dc.creator.none.fl_str_mv Mattana, Claudia Maricel
Satorres, Sara Elena
Escobar, Franco Matias
Sabini, Maria Carola
Sabini, Liliana Ines
Fusco, María del Rosario
Alcaráz, Lucia Esther
author Mattana, Claudia Maricel
author_facet Mattana, Claudia Maricel
Satorres, Sara Elena
Escobar, Franco Matias
Sabini, Maria Carola
Sabini, Liliana Ines
Fusco, María del Rosario
Alcaráz, Lucia Esther
author_role author
author2 Satorres, Sara Elena
Escobar, Franco Matias
Sabini, Maria Carola
Sabini, Liliana Ines
Fusco, María del Rosario
Alcaráz, Lucia Esther
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv ACACIA AROMA
ANTIBACTERIAL ACTIVITY
CYTOTOXICITY
topic ACACIA AROMA
ANTIBACTERIAL ACTIVITY
CYTOTOXICITY
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Acacia aroma, native plant from San Luis, Argentina, is used commonly like antiseptic and healing of wounds. The present study was conducted to investigate the in vitro antibacterial activity of extracts of A. aroma and its toxicity on Vero cell. The bacterial strains used were Staphylococcus aureus ATCC 43300, S. aureus ATCC 35556, Listeria monocytogenes CLIP 74910 and L. monocytogenes CLIP 74904. The minimal inhibitory concentration (MICs) and minimal bactericidal concentration (CBMs) was determined and tested at concentration ranges from 5000 to 78μg/mL. On the other hand, the cytotoxic activity on Vero cells was assayed by MTT method. The MIC values of EE and HAE against S. aureus was 156μg/mL and 625μg/mL respectively. MBC values were one or two fold higher than the corresponding MIC values in both extracts. Listeria strains studied gave MICs and MBCs values of 78μg/mL and 312μg/mLl respectively for EE, while HAE showed less antibacterial activity against this strain (MIC=1250μg/mL and MBC=5000μg/mL). The CC50 was 658μg/mL for EE and 1020μg/mL for HAE. The extracts of A. aroma tested in vitro showed inhibitory activity against Staphylococcus and Listeria. These results allow validating the external use of this plant.
Fil: Mattana, Claudia Maricel. Universidad Nacional de San Luis; Argentina
Fil: Satorres, Sara Elena. Universidad Nacional de San Luis; Argentina
Fil: Escobar, Franco Matias. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto; Argentina
Fil: Sabini, Maria Carola. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto; Argentina
Fil: Sabini, Liliana Ines. Universidad Nacional de Río Cuarto; Argentina
Fil: Fusco, María del Rosario. Universidad Nacional de San Luis; Argentina
Fil: Alcaráz, Lucia Esther. Universidad Nacional de San Luis; Argentina
description Acacia aroma, native plant from San Luis, Argentina, is used commonly like antiseptic and healing of wounds. The present study was conducted to investigate the in vitro antibacterial activity of extracts of A. aroma and its toxicity on Vero cell. The bacterial strains used were Staphylococcus aureus ATCC 43300, S. aureus ATCC 35556, Listeria monocytogenes CLIP 74910 and L. monocytogenes CLIP 74904. The minimal inhibitory concentration (MICs) and minimal bactericidal concentration (CBMs) was determined and tested at concentration ranges from 5000 to 78μg/mL. On the other hand, the cytotoxic activity on Vero cells was assayed by MTT method. The MIC values of EE and HAE against S. aureus was 156μg/mL and 625μg/mL respectively. MBC values were one or two fold higher than the corresponding MIC values in both extracts. Listeria strains studied gave MICs and MBCs values of 78μg/mL and 312μg/mLl respectively for EE, while HAE showed less antibacterial activity against this strain (MIC=1250μg/mL and MBC=5000μg/mL). The CC50 was 658μg/mL for EE and 1020μg/mL for HAE. The extracts of A. aroma tested in vitro showed inhibitory activity against Staphylococcus and Listeria. These results allow validating the external use of this plant.
publishDate 2012
dc.date.none.fl_str_mv 2012-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/282013
Mattana, Claudia Maricel; Satorres, Sara Elena; Escobar, Franco Matias; Sabini, Maria Carola; Sabini, Liliana Ines; et al.; Antibacterial and cytotoxic activities of Acacia aroma extracts; Universidad de Emiratos Árabes Unidos; Emirates Journal of Food and Agriculture; 24; 4; 6-2012; 308-313
2079-052x
2079-0538
CONICET Digital
CONICET
url http://hdl.handle.net/11336/282013
identifier_str_mv Mattana, Claudia Maricel; Satorres, Sara Elena; Escobar, Franco Matias; Sabini, Maria Carola; Sabini, Liliana Ines; et al.; Antibacterial and cytotoxic activities of Acacia aroma extracts; Universidad de Emiratos Árabes Unidos; Emirates Journal of Food and Agriculture; 24; 4; 6-2012; 308-313
2079-052x
2079-0538
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://ejfa.me/index.php/journal/article/view/888
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Universidad de Emiratos Árabes Unidos
publisher.none.fl_str_mv Universidad de Emiratos Árabes Unidos
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.977003

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