Short-term Menhaden Oil Rich Diet Changes Renal Lipid Profile in Acute Kidney Injury

Autores
Ossani, Georgina Paula; Denninghoff, Valeria Cecilia; Uceda, Ana Margarita; Díaz, Maria L.; Uicich, Raúl Eduardo; Monserrat, Alberto Juan
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Weanling male Wistar rats fed a choline-deficient diet develop acute kidney injury. Menhaden oil, which is a very important source of omega-3 fatty acids, has a notorious protective effect. The mechanism of this protection is unknown; one possibility could be that menhaden oil changes renal lipid profile, with an impact on the functions of biological membranes. The aim of this work was to study the renal lipid profile in rats fed a choline-deficient diet with menhaden oil or vegetable oil as lipids. Rats were divided into 4 groups and fed four different diets for 7 days: choline-deficient or choline-supplemented diets with corn and hydrogenated oils or menhaden oil. Serum homocysteine, vitamin B12, and folic acid were analyzed. Renal lipid profile, as well as the fatty acid composition of the three oils, was measured. Choline-deficient rats fed vegetable oils showed renal cortical necrosis. Renal omega-6 fatty acids were higher in rats fed a choline-deficient diet and a choline-supplemented diet with vegetable oils, while renal omega-3 fatty acids were higher in rats fed a choline-deficient diet and a choline-supplemented diet with menhaden oil. Rats fed menhaden oil diets had higher levels of renal eicosapentaenoic and docosahexaenoic acids. Renal myristic acid was increased in rats fed menhaden oil. The lipid renal profile varied quickly according to the type of oil contented in the diet.
Fil: Ossani, Georgina Paula. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Patología. Centro de Patología Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Denninghoff, Valeria Cecilia. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Patología. Centro de Patología Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET.; Argentina
Fil: Uceda, Ana Margarita. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Patología. Centro de Patología Experimental; Argentina
Fil: Díaz, Maria L.. Hospital Británico de Buenos Aires; Argentina
Fil: Uicich, Raúl. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
Fil: Monserrat, Alberto Juan. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Patología. Centro de Patología Experimental; Argentina
Materia
Menhaden Oil
Choline Deficiency
Fatty Acids
Acute Kidney Injury
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/41563
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/41563
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Short-term Menhaden Oil Rich Diet Changes Renal Lipid Profile in Acute Kidney InjuryOssani, Georgina PaulaDenninghoff, Valeria CeciliaUceda, Ana MargaritaDíaz, Maria L.Uicich, Raúl EduardoMonserrat, Alberto JuanMenhaden OilCholine DeficiencyFatty AcidsAcute Kidney Injuryhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Weanling male Wistar rats fed a choline-deficient diet develop acute kidney injury. Menhaden oil, which is a very important source of omega-3 fatty acids, has a notorious protective effect. The mechanism of this protection is unknown; one possibility could be that menhaden oil changes renal lipid profile, with an impact on the functions of biological membranes. The aim of this work was to study the renal lipid profile in rats fed a choline-deficient diet with menhaden oil or vegetable oil as lipids. Rats were divided into 4 groups and fed four different diets for 7 days: choline-deficient or choline-supplemented diets with corn and hydrogenated oils or menhaden oil. Serum homocysteine, vitamin B12, and folic acid were analyzed. Renal lipid profile, as well as the fatty acid composition of the three oils, was measured. Choline-deficient rats fed vegetable oils showed renal cortical necrosis. Renal omega-6 fatty acids were higher in rats fed a choline-deficient diet and a choline-supplemented diet with vegetable oils, while renal omega-3 fatty acids were higher in rats fed a choline-deficient diet and a choline-supplemented diet with menhaden oil. Rats fed menhaden oil diets had higher levels of renal eicosapentaenoic and docosahexaenoic acids. Renal myristic acid was increased in rats fed menhaden oil. The lipid renal profile varied quickly according to the type of oil contented in the diet.Fil: Ossani, Georgina Paula. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Patología. Centro de Patología Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Denninghoff, Valeria Cecilia. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Patología. Centro de Patología Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET.; ArgentinaFil: Uceda, Ana Margarita. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Patología. Centro de Patología Experimental; ArgentinaFil: Díaz, Maria L.. Hospital Británico de Buenos Aires; ArgentinaFil: Uicich, Raúl. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaFil: Monserrat, Alberto Juan. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Patología. Centro de Patología Experimental; ArgentinaJapan Oil Chemists’ Society2015-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/41563Ossani, Georgina Paula; Denninghoff, Valeria Cecilia; Uceda, Ana Margarita; Díaz, Maria L.; Uicich, Raúl Eduardo; et al.; Short-term Menhaden Oil Rich Diet Changes Renal Lipid Profile in Acute Kidney Injury; Japan Oil Chemists’ Society; Journal of Oleo Science; 64; 5; 5-2015; 497-5031345-89571347-3352CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.5650/jos.ess14186info:eu-repo/semantics/altIdentifier/url/https://www.jstage.jst.go.jp/article/jos/64/5/64_ess14186/_articleinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:54:06Zoai:ri.conicet.gov.ar:11336/41563instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:54:06.953CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Short-term Menhaden Oil Rich Diet Changes Renal Lipid Profile in Acute Kidney Injury
title Short-term Menhaden Oil Rich Diet Changes Renal Lipid Profile in Acute Kidney Injury
spellingShingle Short-term Menhaden Oil Rich Diet Changes Renal Lipid Profile in Acute Kidney Injury
Ossani, Georgina Paula
Menhaden Oil
Choline Deficiency
Fatty Acids
Acute Kidney Injury
title_short Short-term Menhaden Oil Rich Diet Changes Renal Lipid Profile in Acute Kidney Injury
title_full Short-term Menhaden Oil Rich Diet Changes Renal Lipid Profile in Acute Kidney Injury
title_fullStr Short-term Menhaden Oil Rich Diet Changes Renal Lipid Profile in Acute Kidney Injury
title_full_unstemmed Short-term Menhaden Oil Rich Diet Changes Renal Lipid Profile in Acute Kidney Injury
title_sort Short-term Menhaden Oil Rich Diet Changes Renal Lipid Profile in Acute Kidney Injury
dc.creator.none.fl_str_mv Ossani, Georgina Paula
Denninghoff, Valeria Cecilia
Uceda, Ana Margarita
Díaz, Maria L.
Uicich, Raúl Eduardo
Monserrat, Alberto Juan
author Ossani, Georgina Paula
author_facet Ossani, Georgina Paula
Denninghoff, Valeria Cecilia
Uceda, Ana Margarita
Díaz, Maria L.
Uicich, Raúl Eduardo
Monserrat, Alberto Juan
author_role author
author2 Denninghoff, Valeria Cecilia
Uceda, Ana Margarita
Díaz, Maria L.
Uicich, Raúl Eduardo
Monserrat, Alberto Juan
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Menhaden Oil
Choline Deficiency
Fatty Acids
Acute Kidney Injury
topic Menhaden Oil
Choline Deficiency
Fatty Acids
Acute Kidney Injury
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Weanling male Wistar rats fed a choline-deficient diet develop acute kidney injury. Menhaden oil, which is a very important source of omega-3 fatty acids, has a notorious protective effect. The mechanism of this protection is unknown; one possibility could be that menhaden oil changes renal lipid profile, with an impact on the functions of biological membranes. The aim of this work was to study the renal lipid profile in rats fed a choline-deficient diet with menhaden oil or vegetable oil as lipids. Rats were divided into 4 groups and fed four different diets for 7 days: choline-deficient or choline-supplemented diets with corn and hydrogenated oils or menhaden oil. Serum homocysteine, vitamin B12, and folic acid were analyzed. Renal lipid profile, as well as the fatty acid composition of the three oils, was measured. Choline-deficient rats fed vegetable oils showed renal cortical necrosis. Renal omega-6 fatty acids were higher in rats fed a choline-deficient diet and a choline-supplemented diet with vegetable oils, while renal omega-3 fatty acids were higher in rats fed a choline-deficient diet and a choline-supplemented diet with menhaden oil. Rats fed menhaden oil diets had higher levels of renal eicosapentaenoic and docosahexaenoic acids. Renal myristic acid was increased in rats fed menhaden oil. The lipid renal profile varied quickly according to the type of oil contented in the diet.
Fil: Ossani, Georgina Paula. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Patología. Centro de Patología Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Denninghoff, Valeria Cecilia. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Patología. Centro de Patología Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET.; Argentina
Fil: Uceda, Ana Margarita. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Patología. Centro de Patología Experimental; Argentina
Fil: Díaz, Maria L.. Hospital Británico de Buenos Aires; Argentina
Fil: Uicich, Raúl. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
Fil: Monserrat, Alberto Juan. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Patología. Centro de Patología Experimental; Argentina
description Weanling male Wistar rats fed a choline-deficient diet develop acute kidney injury. Menhaden oil, which is a very important source of omega-3 fatty acids, has a notorious protective effect. The mechanism of this protection is unknown; one possibility could be that menhaden oil changes renal lipid profile, with an impact on the functions of biological membranes. The aim of this work was to study the renal lipid profile in rats fed a choline-deficient diet with menhaden oil or vegetable oil as lipids. Rats were divided into 4 groups and fed four different diets for 7 days: choline-deficient or choline-supplemented diets with corn and hydrogenated oils or menhaden oil. Serum homocysteine, vitamin B12, and folic acid were analyzed. Renal lipid profile, as well as the fatty acid composition of the three oils, was measured. Choline-deficient rats fed vegetable oils showed renal cortical necrosis. Renal omega-6 fatty acids were higher in rats fed a choline-deficient diet and a choline-supplemented diet with vegetable oils, while renal omega-3 fatty acids were higher in rats fed a choline-deficient diet and a choline-supplemented diet with menhaden oil. Rats fed menhaden oil diets had higher levels of renal eicosapentaenoic and docosahexaenoic acids. Renal myristic acid was increased in rats fed menhaden oil. The lipid renal profile varied quickly according to the type of oil contented in the diet.
publishDate 2015
dc.date.none.fl_str_mv 2015-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/41563
Ossani, Georgina Paula; Denninghoff, Valeria Cecilia; Uceda, Ana Margarita; Díaz, Maria L.; Uicich, Raúl Eduardo; et al.; Short-term Menhaden Oil Rich Diet Changes Renal Lipid Profile in Acute Kidney Injury; Japan Oil Chemists’ Society; Journal of Oleo Science; 64; 5; 5-2015; 497-503
1345-8957
1347-3352
CONICET Digital
CONICET
url http://hdl.handle.net/11336/41563
identifier_str_mv Ossani, Georgina Paula; Denninghoff, Valeria Cecilia; Uceda, Ana Margarita; Díaz, Maria L.; Uicich, Raúl Eduardo; et al.; Short-term Menhaden Oil Rich Diet Changes Renal Lipid Profile in Acute Kidney Injury; Japan Oil Chemists’ Society; Journal of Oleo Science; 64; 5; 5-2015; 497-503
1345-8957
1347-3352
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.5650/jos.ess14186
info:eu-repo/semantics/altIdentifier/url/https://www.jstage.jst.go.jp/article/jos/64/5/64_ess14186/_article
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Japan Oil Chemists’ Society
publisher.none.fl_str_mv Japan Oil Chemists’ Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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