Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats

Autores
Denzoin, Laura; Franci, Rodolfo J.; Tapia, Maria Ofelia; Soraci, Alejandro Luis
Año de publicación
2008
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Glutathione is an important intracellular tripeptide with multiple functions. Abnormal glutathione metabolism is thought to play an important role in various diseases of cats. However, no data regarding concentration of plasma glutathione are available for domestic cats. This study discusses the development of a rapid, simple high pressure liquid chromatography method for measurement of reduced glutathione (GSH), oxidized glutathione (GSSH) and total glutathione (GSHt) in plasma, for the purpose of establishing baseline data for future studies. The mean concentrations of GSH, GSSH and GSHt were 4.51 1 mM; 19.44 3.79 mM (expressed as GSH equivalent) and 23.59 3.89 mM, respectively. This is the first report of plasma glutathione mM; 19.44 3.79 mM (expressed as GSH equivalent) and 23.59 3.89 mM, respectively. This is the first report of plasma glutathione concentrations in this species.
Fil: Denzoin, Laura. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; Argentina
Fil: Franci, Rodolfo J.. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Clínicas; Argentina
Fil: Tapia, Maria Ofelia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; Argentina
Fil: Soraci, Alejandro Luis. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
REDUCED GLUTATHIONE
OXIDIZED GLUTATHIONE
PLASMA TOTAL GLUTATHIONE
CATS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/103810
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/103810
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy catsDenzoin, LauraFranci, Rodolfo J.Tapia, Maria OfeliaSoraci, Alejandro LuisREDUCED GLUTATHIONEOXIDIZED GLUTATHIONEPLASMA TOTAL GLUTATHIONECATShttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4Glutathione is an important intracellular tripeptide with multiple functions. Abnormal glutathione metabolism is thought to play an important role in various diseases of cats. However, no data regarding concentration of plasma glutathione are available for domestic cats. This study discusses the development of a rapid, simple high pressure liquid chromatography method for measurement of reduced glutathione (GSH), oxidized glutathione (GSSH) and total glutathione (GSHt) in plasma, for the purpose of establishing baseline data for future studies. The mean concentrations of GSH, GSSH and GSHt were 4.51 1 mM; 19.44 3.79 mM (expressed as GSH equivalent) and 23.59 3.89 mM, respectively. This is the first report of plasma glutathione mM; 19.44 3.79 mM (expressed as GSH equivalent) and 23.59 3.89 mM, respectively. This is the first report of plasma glutathione concentrations in this species.Fil: Denzoin, Laura. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; ArgentinaFil: Franci, Rodolfo J.. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Clínicas; ArgentinaFil: Tapia, Maria Ofelia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; ArgentinaFil: Soraci, Alejandro Luis. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaElsevier2008-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/103810Denzoin, Laura; Franci, Rodolfo J.; Tapia, Maria Ofelia; Soraci, Alejandro Luis; Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats; Elsevier; Journal of Feline Medicine and Surgery; 10; 3; 7-2008; 230-2341098-612XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.jfms.2007.11.005info:eu-repo/semantics/altIdentifier/url/https://journals.sagepub.com/doi/10.1016/j.jfms.2007.11.005info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:38:08Zoai:ri.conicet.gov.ar:11336/103810instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:38:08.959CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats
title Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats
spellingShingle Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats
Denzoin, Laura
REDUCED GLUTATHIONE
OXIDIZED GLUTATHIONE
PLASMA TOTAL GLUTATHIONE
CATS
title_short Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats
title_full Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats
title_fullStr Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats
title_full_unstemmed Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats
title_sort Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats
dc.creator.none.fl_str_mv Denzoin, Laura
Franci, Rodolfo J.
Tapia, Maria Ofelia
Soraci, Alejandro Luis
author Denzoin, Laura
author_facet Denzoin, Laura
Franci, Rodolfo J.
Tapia, Maria Ofelia
Soraci, Alejandro Luis
author_role author
author2 Franci, Rodolfo J.
Tapia, Maria Ofelia
Soraci, Alejandro Luis
author2_role author
author
author
dc.subject.none.fl_str_mv REDUCED GLUTATHIONE
OXIDIZED GLUTATHIONE
PLASMA TOTAL GLUTATHIONE
CATS
topic REDUCED GLUTATHIONE
OXIDIZED GLUTATHIONE
PLASMA TOTAL GLUTATHIONE
CATS
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv Glutathione is an important intracellular tripeptide with multiple functions. Abnormal glutathione metabolism is thought to play an important role in various diseases of cats. However, no data regarding concentration of plasma glutathione are available for domestic cats. This study discusses the development of a rapid, simple high pressure liquid chromatography method for measurement of reduced glutathione (GSH), oxidized glutathione (GSSH) and total glutathione (GSHt) in plasma, for the purpose of establishing baseline data for future studies. The mean concentrations of GSH, GSSH and GSHt were 4.51 1 mM; 19.44 3.79 mM (expressed as GSH equivalent) and 23.59 3.89 mM, respectively. This is the first report of plasma glutathione mM; 19.44 3.79 mM (expressed as GSH equivalent) and 23.59 3.89 mM, respectively. This is the first report of plasma glutathione concentrations in this species.
Fil: Denzoin, Laura. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; Argentina
Fil: Franci, Rodolfo J.. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Clínicas; Argentina
Fil: Tapia, Maria Ofelia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; Argentina
Fil: Soraci, Alejandro Luis. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description Glutathione is an important intracellular tripeptide with multiple functions. Abnormal glutathione metabolism is thought to play an important role in various diseases of cats. However, no data regarding concentration of plasma glutathione are available for domestic cats. This study discusses the development of a rapid, simple high pressure liquid chromatography method for measurement of reduced glutathione (GSH), oxidized glutathione (GSSH) and total glutathione (GSHt) in plasma, for the purpose of establishing baseline data for future studies. The mean concentrations of GSH, GSSH and GSHt were 4.51 1 mM; 19.44 3.79 mM (expressed as GSH equivalent) and 23.59 3.89 mM, respectively. This is the first report of plasma glutathione mM; 19.44 3.79 mM (expressed as GSH equivalent) and 23.59 3.89 mM, respectively. This is the first report of plasma glutathione concentrations in this species.
publishDate 2008
dc.date.none.fl_str_mv 2008-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/103810
Denzoin, Laura; Franci, Rodolfo J.; Tapia, Maria Ofelia; Soraci, Alejandro Luis; Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats; Elsevier; Journal of Feline Medicine and Surgery; 10; 3; 7-2008; 230-234
1098-612X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/103810
identifier_str_mv Denzoin, Laura; Franci, Rodolfo J.; Tapia, Maria Ofelia; Soraci, Alejandro Luis; Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats; Elsevier; Journal of Feline Medicine and Surgery; 10; 3; 7-2008; 230-234
1098-612X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jfms.2007.11.005
info:eu-repo/semantics/altIdentifier/url/https://journals.sagepub.com/doi/10.1016/j.jfms.2007.11.005
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.069144

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