Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats
- Autores
- Denzoin, Laura; Franci, Rodolfo J.; Tapia, Maria Ofelia; Soraci, Alejandro Luis
- Año de publicación
- 2008
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Glutathione is an important intracellular tripeptide with multiple functions. Abnormal glutathione metabolism is thought to play an important role in various diseases of cats. However, no data regarding concentration of plasma glutathione are available for domestic cats. This study discusses the development of a rapid, simple high pressure liquid chromatography method for measurement of reduced glutathione (GSH), oxidized glutathione (GSSH) and total glutathione (GSHt) in plasma, for the purpose of establishing baseline data for future studies. The mean concentrations of GSH, GSSH and GSHt were 4.51 1 mM; 19.44 3.79 mM (expressed as GSH equivalent) and 23.59 3.89 mM, respectively. This is the first report of plasma glutathione mM; 19.44 3.79 mM (expressed as GSH equivalent) and 23.59 3.89 mM, respectively. This is the first report of plasma glutathione concentrations in this species.
Fil: Denzoin, Laura. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; Argentina
Fil: Franci, Rodolfo J.. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Clínicas; Argentina
Fil: Tapia, Maria Ofelia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; Argentina
Fil: Soraci, Alejandro Luis. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina - Materia
-
REDUCED GLUTATHIONE
OXIDIZED GLUTATHIONE
PLASMA TOTAL GLUTATHIONE
CATS - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/103810
Ver los metadatos del registro completo
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Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy catsDenzoin, LauraFranci, Rodolfo J.Tapia, Maria OfeliaSoraci, Alejandro LuisREDUCED GLUTATHIONEOXIDIZED GLUTATHIONEPLASMA TOTAL GLUTATHIONECATShttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4Glutathione is an important intracellular tripeptide with multiple functions. Abnormal glutathione metabolism is thought to play an important role in various diseases of cats. However, no data regarding concentration of plasma glutathione are available for domestic cats. This study discusses the development of a rapid, simple high pressure liquid chromatography method for measurement of reduced glutathione (GSH), oxidized glutathione (GSSH) and total glutathione (GSHt) in plasma, for the purpose of establishing baseline data for future studies. The mean concentrations of GSH, GSSH and GSHt were 4.51 1 mM; 19.44 3.79 mM (expressed as GSH equivalent) and 23.59 3.89 mM, respectively. This is the first report of plasma glutathione mM; 19.44 3.79 mM (expressed as GSH equivalent) and 23.59 3.89 mM, respectively. This is the first report of plasma glutathione concentrations in this species.Fil: Denzoin, Laura. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; ArgentinaFil: Franci, Rodolfo J.. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Clínicas; ArgentinaFil: Tapia, Maria Ofelia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; ArgentinaFil: Soraci, Alejandro Luis. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaElsevier2008-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/103810Denzoin, Laura; Franci, Rodolfo J.; Tapia, Maria Ofelia; Soraci, Alejandro Luis; Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats; Elsevier; Journal of Feline Medicine and Surgery; 10; 3; 7-2008; 230-2341098-612XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.jfms.2007.11.005info:eu-repo/semantics/altIdentifier/url/https://journals.sagepub.com/doi/10.1016/j.jfms.2007.11.005info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:46:44Zoai:ri.conicet.gov.ar:11336/103810instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:46:44.684CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats |
title |
Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats |
spellingShingle |
Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats Denzoin, Laura REDUCED GLUTATHIONE OXIDIZED GLUTATHIONE PLASMA TOTAL GLUTATHIONE CATS |
title_short |
Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats |
title_full |
Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats |
title_fullStr |
Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats |
title_full_unstemmed |
Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats |
title_sort |
Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats |
dc.creator.none.fl_str_mv |
Denzoin, Laura Franci, Rodolfo J. Tapia, Maria Ofelia Soraci, Alejandro Luis |
author |
Denzoin, Laura |
author_facet |
Denzoin, Laura Franci, Rodolfo J. Tapia, Maria Ofelia Soraci, Alejandro Luis |
author_role |
author |
author2 |
Franci, Rodolfo J. Tapia, Maria Ofelia Soraci, Alejandro Luis |
author2_role |
author author author |
dc.subject.none.fl_str_mv |
REDUCED GLUTATHIONE OXIDIZED GLUTATHIONE PLASMA TOTAL GLUTATHIONE CATS |
topic |
REDUCED GLUTATHIONE OXIDIZED GLUTATHIONE PLASMA TOTAL GLUTATHIONE CATS |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/4.3 https://purl.org/becyt/ford/4 |
dc.description.none.fl_txt_mv |
Glutathione is an important intracellular tripeptide with multiple functions. Abnormal glutathione metabolism is thought to play an important role in various diseases of cats. However, no data regarding concentration of plasma glutathione are available for domestic cats. This study discusses the development of a rapid, simple high pressure liquid chromatography method for measurement of reduced glutathione (GSH), oxidized glutathione (GSSH) and total glutathione (GSHt) in plasma, for the purpose of establishing baseline data for future studies. The mean concentrations of GSH, GSSH and GSHt were 4.51 1 mM; 19.44 3.79 mM (expressed as GSH equivalent) and 23.59 3.89 mM, respectively. This is the first report of plasma glutathione mM; 19.44 3.79 mM (expressed as GSH equivalent) and 23.59 3.89 mM, respectively. This is the first report of plasma glutathione concentrations in this species. Fil: Denzoin, Laura. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; Argentina Fil: Franci, Rodolfo J.. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Clínicas; Argentina Fil: Tapia, Maria Ofelia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; Argentina Fil: Soraci, Alejandro Luis. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina |
description |
Glutathione is an important intracellular tripeptide with multiple functions. Abnormal glutathione metabolism is thought to play an important role in various diseases of cats. However, no data regarding concentration of plasma glutathione are available for domestic cats. This study discusses the development of a rapid, simple high pressure liquid chromatography method for measurement of reduced glutathione (GSH), oxidized glutathione (GSSH) and total glutathione (GSHt) in plasma, for the purpose of establishing baseline data for future studies. The mean concentrations of GSH, GSSH and GSHt were 4.51 1 mM; 19.44 3.79 mM (expressed as GSH equivalent) and 23.59 3.89 mM, respectively. This is the first report of plasma glutathione mM; 19.44 3.79 mM (expressed as GSH equivalent) and 23.59 3.89 mM, respectively. This is the first report of plasma glutathione concentrations in this species. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-07 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/103810 Denzoin, Laura; Franci, Rodolfo J.; Tapia, Maria Ofelia; Soraci, Alejandro Luis; Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats; Elsevier; Journal of Feline Medicine and Surgery; 10; 3; 7-2008; 230-234 1098-612X CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/103810 |
identifier_str_mv |
Denzoin, Laura; Franci, Rodolfo J.; Tapia, Maria Ofelia; Soraci, Alejandro Luis; Quantification of plasma reduced glutathione, oxidized glutathione and plasma total glutathione in healthy cats; Elsevier; Journal of Feline Medicine and Surgery; 10; 3; 7-2008; 230-234 1098-612X CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jfms.2007.11.005 info:eu-repo/semantics/altIdentifier/url/https://journals.sagepub.com/doi/10.1016/j.jfms.2007.11.005 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1842268813006995456 |
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13.13397 |