Ethanol Perinatal Exposure Induces Behavioral Alterations and Ethanol Preference in Adolescent Wistar Rats

Autores
Aronne, María Paula; Alimonta Rios, Ruben; Pecile, Andrea Noemi; Brusco, Herminia Alicia
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Ethanol-perinatally-exposed (EPE)Wistar rats show central nervous system morphological alterations that persist until adulthood. The aim of this work was to study whether adolescent EPE rats present alterations in behavior and develop ethanol (EtOH) preference. For behavioral analyses, locomotor and exploratory activity, anxiety and long-term memory standardized tests were performed on 40 to 45 dayold male rats. Another group of rats chose to drink between EtOH and water using the model of preference between two bottles, one with EtOH 6% v/v and the other with water. During eight weeks, the volume of EtOH consumed/kg/day was registered and blood EtOH concentration was determined at the end of the experiment. Results in EPE rats show a decrease in aerial exploration and anxiety, while locomotor activity and long-term memory were not affected. Bothmale and female EPE rats preferred EtOH earlier than control rats, showing a highest level of blood EtOH concentration.
Fil: Aronne, María Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencias "profesor Eduardo de Robertis"; Argentina
Fil: Alimonta Rios, Ruben. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencias "profesor Eduardo de Robertis"; Argentina
Fil: Pecile, Andrea Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencias "profesor Eduardo de Robertis"; Argentina
Fil: Brusco, Herminia Alicia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencias "profesor Eduardo de Robertis"; Argentina
Materia
ETHANOL PREFERENCE
ADOLESCENT RATS
PERINATAL ETHANOL EXPOSITION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/8515
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Ethanol Perinatal Exposure Induces Behavioral Alterations and Ethanol Preference in Adolescent Wistar RatsAronne, María PaulaAlimonta Rios, RubenPecile, Andrea NoemiBrusco, Herminia AliciaETHANOL PREFERENCEADOLESCENT RATSPERINATAL ETHANOL EXPOSITIONhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Ethanol-perinatally-exposed (EPE)Wistar rats show central nervous system morphological alterations that persist until adulthood. The aim of this work was to study whether adolescent EPE rats present alterations in behavior and develop ethanol (EtOH) preference. For behavioral analyses, locomotor and exploratory activity, anxiety and long-term memory standardized tests were performed on 40 to 45 dayold male rats. Another group of rats chose to drink between EtOH and water using the model of preference between two bottles, one with EtOH 6% v/v and the other with water. During eight weeks, the volume of EtOH consumed/kg/day was registered and blood EtOH concentration was determined at the end of the experiment. Results in EPE rats show a decrease in aerial exploration and anxiety, while locomotor activity and long-term memory were not affected. Bothmale and female EPE rats preferred EtOH earlier than control rats, showing a highest level of blood EtOH concentration.Fil: Aronne, María Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencias "profesor Eduardo de Robertis"; ArgentinaFil: Alimonta Rios, Ruben. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencias "profesor Eduardo de Robertis"; ArgentinaFil: Pecile, Andrea Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencias "profesor Eduardo de Robertis"; ArgentinaFil: Brusco, Herminia Alicia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencias "profesor Eduardo de Robertis"; ArgentinaAshdin Publishing2013-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/8515Aronne, María Paula; Alimonta Rios, Ruben; Pecile, Andrea Noemi; Brusco, Herminia Alicia; Ethanol Perinatal Exposure Induces Behavioral Alterations and Ethanol Preference in Adolescent Wistar Rats; Ashdin Publishing; Journal of Drug and Alcohol Research; 2; 10-2013; 1-9; 2357912090-8342enginfo:eu-repo/semantics/altIdentifier/url/http://www.ashdin.com/journals/JDAR/235791/info:eu-repo/semantics/altIdentifier/doi/10.4303/jdar/235791info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:31:57Zoai:ri.conicet.gov.ar:11336/8515instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:31:57.928CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Ethanol Perinatal Exposure Induces Behavioral Alterations and Ethanol Preference in Adolescent Wistar Rats
title Ethanol Perinatal Exposure Induces Behavioral Alterations and Ethanol Preference in Adolescent Wistar Rats
spellingShingle Ethanol Perinatal Exposure Induces Behavioral Alterations and Ethanol Preference in Adolescent Wistar Rats
Aronne, María Paula
ETHANOL PREFERENCE
ADOLESCENT RATS
PERINATAL ETHANOL EXPOSITION
title_short Ethanol Perinatal Exposure Induces Behavioral Alterations and Ethanol Preference in Adolescent Wistar Rats
title_full Ethanol Perinatal Exposure Induces Behavioral Alterations and Ethanol Preference in Adolescent Wistar Rats
title_fullStr Ethanol Perinatal Exposure Induces Behavioral Alterations and Ethanol Preference in Adolescent Wistar Rats
title_full_unstemmed Ethanol Perinatal Exposure Induces Behavioral Alterations and Ethanol Preference in Adolescent Wistar Rats
title_sort Ethanol Perinatal Exposure Induces Behavioral Alterations and Ethanol Preference in Adolescent Wistar Rats
dc.creator.none.fl_str_mv Aronne, María Paula
Alimonta Rios, Ruben
Pecile, Andrea Noemi
Brusco, Herminia Alicia
author Aronne, María Paula
author_facet Aronne, María Paula
Alimonta Rios, Ruben
Pecile, Andrea Noemi
Brusco, Herminia Alicia
author_role author
author2 Alimonta Rios, Ruben
Pecile, Andrea Noemi
Brusco, Herminia Alicia
author2_role author
author
author
dc.subject.none.fl_str_mv ETHANOL PREFERENCE
ADOLESCENT RATS
PERINATAL ETHANOL EXPOSITION
topic ETHANOL PREFERENCE
ADOLESCENT RATS
PERINATAL ETHANOL EXPOSITION
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Ethanol-perinatally-exposed (EPE)Wistar rats show central nervous system morphological alterations that persist until adulthood. The aim of this work was to study whether adolescent EPE rats present alterations in behavior and develop ethanol (EtOH) preference. For behavioral analyses, locomotor and exploratory activity, anxiety and long-term memory standardized tests were performed on 40 to 45 dayold male rats. Another group of rats chose to drink between EtOH and water using the model of preference between two bottles, one with EtOH 6% v/v and the other with water. During eight weeks, the volume of EtOH consumed/kg/day was registered and blood EtOH concentration was determined at the end of the experiment. Results in EPE rats show a decrease in aerial exploration and anxiety, while locomotor activity and long-term memory were not affected. Bothmale and female EPE rats preferred EtOH earlier than control rats, showing a highest level of blood EtOH concentration.
Fil: Aronne, María Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencias "profesor Eduardo de Robertis"; Argentina
Fil: Alimonta Rios, Ruben. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencias "profesor Eduardo de Robertis"; Argentina
Fil: Pecile, Andrea Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencias "profesor Eduardo de Robertis"; Argentina
Fil: Brusco, Herminia Alicia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencias "profesor Eduardo de Robertis"; Argentina
description Ethanol-perinatally-exposed (EPE)Wistar rats show central nervous system morphological alterations that persist until adulthood. The aim of this work was to study whether adolescent EPE rats present alterations in behavior and develop ethanol (EtOH) preference. For behavioral analyses, locomotor and exploratory activity, anxiety and long-term memory standardized tests were performed on 40 to 45 dayold male rats. Another group of rats chose to drink between EtOH and water using the model of preference between two bottles, one with EtOH 6% v/v and the other with water. During eight weeks, the volume of EtOH consumed/kg/day was registered and blood EtOH concentration was determined at the end of the experiment. Results in EPE rats show a decrease in aerial exploration and anxiety, while locomotor activity and long-term memory were not affected. Bothmale and female EPE rats preferred EtOH earlier than control rats, showing a highest level of blood EtOH concentration.
publishDate 2013
dc.date.none.fl_str_mv 2013-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/8515
Aronne, María Paula; Alimonta Rios, Ruben; Pecile, Andrea Noemi; Brusco, Herminia Alicia; Ethanol Perinatal Exposure Induces Behavioral Alterations and Ethanol Preference in Adolescent Wistar Rats; Ashdin Publishing; Journal of Drug and Alcohol Research; 2; 10-2013; 1-9; 235791
2090-8342
url http://hdl.handle.net/11336/8515
identifier_str_mv Aronne, María Paula; Alimonta Rios, Ruben; Pecile, Andrea Noemi; Brusco, Herminia Alicia; Ethanol Perinatal Exposure Induces Behavioral Alterations and Ethanol Preference in Adolescent Wistar Rats; Ashdin Publishing; Journal of Drug and Alcohol Research; 2; 10-2013; 1-9; 235791
2090-8342
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.ashdin.com/journals/JDAR/235791/
info:eu-repo/semantics/altIdentifier/doi/10.4303/jdar/235791
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Ashdin Publishing
publisher.none.fl_str_mv Ashdin Publishing
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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