Rhodococcus as Biofactories for Microbial Oil Production

Autores
Alvarez, Hector Manuel; Hernández, Martín Alejandro; Lanfranconi, Mariana Patricia; Silva, Roxana Alejandra; Villalba, María Soledad
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Bacteria belonging to the Rhodococcus genus are frequent components of microbial communitiesin diverse natural environments. Some rhodococcal species exhibit the outstanding ability toproduce significant amounts of triacylglycerols (TAG) (>20% of cellular dry weight) in the presenceof an excess of the carbon source and limitation of the nitrogen source. For this reason, they canbe considered as oleaginous microorganisms. As occurs as well in eukaryotic single-cell oil (SCO)producers, these bacteria possess specific physiological properties and molecular mechanisms that differentiate them from other microorganisms unable to synthesize TAG. In this review, we summarized several of the well-characterized molecular mechanisms that enable oleaginous rhodococci to produce significant amounts of SCO. Furthermore, we highlighted the ability of these microorganisms to degrade a wide range of carbon sources coupled to lipogenesis. The qualitative and quantitative oil production by rhodococci from diverse industrial wastes has also been included. Finally, we summarized the genetic and metabolic approaches applied to oleaginous rhodococci to improve SCO production. This review provides a comprehensive and integrating vision on the potential of oleaginous rhodococci to be considered as microbial biofactories for microbial oil production.
Fil: Alvarez, Hector Manuel. Universidad Nacional de la Patagonia "San Juan Bosco". Instituto de Biociencias de la Patagonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto de Biociencias de la Patagonia; Argentina
Fil: Hernández, Martín Alejandro. Universidad Nacional de la Patagonia "San Juan Bosco". Instituto de Biociencias de la Patagonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto de Biociencias de la Patagonia; Argentina
Fil: Lanfranconi, Mariana Patricia. Universidad Nacional de la Patagonia "San Juan Bosco". Instituto de Biociencias de la Patagonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto de Biociencias de la Patagonia; Argentina
Fil: Silva, Roxana Alejandra. Universidad Nacional de la Patagonia "San Juan Bosco". Instituto de Biociencias de la Patagonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto de Biociencias de la Patagonia; Argentina
Fil: Villalba, María Soledad. Universidad Nacional de la Patagonia "San Juan Bosco". Instituto de Biociencias de la Patagonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto de Biociencias de la Patagonia; Argentina
Materia
RHODOCOCCUS
SINGLE-CELL OIL
BIOFACTORY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/170210
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/170210
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Rhodococcus as Biofactories for Microbial Oil ProductionAlvarez, Hector ManuelHernández, Martín AlejandroLanfranconi, Mariana PatriciaSilva, Roxana AlejandraVillalba, María SoledadRHODOCOCCUSSINGLE-CELL OILBIOFACTORYhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Bacteria belonging to the Rhodococcus genus are frequent components of microbial communitiesin diverse natural environments. Some rhodococcal species exhibit the outstanding ability toproduce significant amounts of triacylglycerols (TAG) (>20% of cellular dry weight) in the presenceof an excess of the carbon source and limitation of the nitrogen source. For this reason, they canbe considered as oleaginous microorganisms. As occurs as well in eukaryotic single-cell oil (SCO)producers, these bacteria possess specific physiological properties and molecular mechanisms that differentiate them from other microorganisms unable to synthesize TAG. In this review, we summarized several of the well-characterized molecular mechanisms that enable oleaginous rhodococci to produce significant amounts of SCO. Furthermore, we highlighted the ability of these microorganisms to degrade a wide range of carbon sources coupled to lipogenesis. The qualitative and quantitative oil production by rhodococci from diverse industrial wastes has also been included. Finally, we summarized the genetic and metabolic approaches applied to oleaginous rhodococci to improve SCO production. This review provides a comprehensive and integrating vision on the potential of oleaginous rhodococci to be considered as microbial biofactories for microbial oil production.Fil: Alvarez, Hector Manuel. Universidad Nacional de la Patagonia "San Juan Bosco". Instituto de Biociencias de la Patagonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto de Biociencias de la Patagonia; ArgentinaFil: Hernández, Martín Alejandro. Universidad Nacional de la Patagonia "San Juan Bosco". Instituto de Biociencias de la Patagonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto de Biociencias de la Patagonia; ArgentinaFil: Lanfranconi, Mariana Patricia. Universidad Nacional de la Patagonia "San Juan Bosco". Instituto de Biociencias de la Patagonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto de Biociencias de la Patagonia; ArgentinaFil: Silva, Roxana Alejandra. Universidad Nacional de la Patagonia "San Juan Bosco". Instituto de Biociencias de la Patagonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto de Biociencias de la Patagonia; ArgentinaFil: Villalba, María Soledad. Universidad Nacional de la Patagonia "San Juan Bosco". Instituto de Biociencias de la Patagonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto de Biociencias de la Patagonia; ArgentinaMolecular Diversity Preservation International2021-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/170210Alvarez, Hector Manuel; Hernández, Martín Alejandro; Lanfranconi, Mariana Patricia; Silva, Roxana Alejandra; Villalba, María Soledad; Rhodococcus as Biofactories for Microbial Oil Production; Molecular Diversity Preservation International; Molecules; 26; 16; 8-2021; 1-271420-3049CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.3390/molecules26164871info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/1420-3049/26/16/4871info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2026-01-14T12:44:32Zoai:ri.conicet.gov.ar:11336/170210instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982026-01-14 12:44:32.39CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Rhodococcus as Biofactories for Microbial Oil Production
title Rhodococcus as Biofactories for Microbial Oil Production
spellingShingle Rhodococcus as Biofactories for Microbial Oil Production
Alvarez, Hector Manuel
RHODOCOCCUS
SINGLE-CELL OIL
BIOFACTORY
title_short Rhodococcus as Biofactories for Microbial Oil Production
title_full Rhodococcus as Biofactories for Microbial Oil Production
title_fullStr Rhodococcus as Biofactories for Microbial Oil Production
title_full_unstemmed Rhodococcus as Biofactories for Microbial Oil Production
title_sort Rhodococcus as Biofactories for Microbial Oil Production
dc.creator.none.fl_str_mv Alvarez, Hector Manuel
Hernández, Martín Alejandro
Lanfranconi, Mariana Patricia
Silva, Roxana Alejandra
Villalba, María Soledad
author Alvarez, Hector Manuel
author_facet Alvarez, Hector Manuel
Hernández, Martín Alejandro
Lanfranconi, Mariana Patricia
Silva, Roxana Alejandra
Villalba, María Soledad
author_role author
author2 Hernández, Martín Alejandro
Lanfranconi, Mariana Patricia
Silva, Roxana Alejandra
Villalba, María Soledad
author2_role author
author
author
author
dc.subject.none.fl_str_mv RHODOCOCCUS
SINGLE-CELL OIL
BIOFACTORY
topic RHODOCOCCUS
SINGLE-CELL OIL
BIOFACTORY
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Bacteria belonging to the Rhodococcus genus are frequent components of microbial communitiesin diverse natural environments. Some rhodococcal species exhibit the outstanding ability toproduce significant amounts of triacylglycerols (TAG) (>20% of cellular dry weight) in the presenceof an excess of the carbon source and limitation of the nitrogen source. For this reason, they canbe considered as oleaginous microorganisms. As occurs as well in eukaryotic single-cell oil (SCO)producers, these bacteria possess specific physiological properties and molecular mechanisms that differentiate them from other microorganisms unable to synthesize TAG. In this review, we summarized several of the well-characterized molecular mechanisms that enable oleaginous rhodococci to produce significant amounts of SCO. Furthermore, we highlighted the ability of these microorganisms to degrade a wide range of carbon sources coupled to lipogenesis. The qualitative and quantitative oil production by rhodococci from diverse industrial wastes has also been included. Finally, we summarized the genetic and metabolic approaches applied to oleaginous rhodococci to improve SCO production. This review provides a comprehensive and integrating vision on the potential of oleaginous rhodococci to be considered as microbial biofactories for microbial oil production.
Fil: Alvarez, Hector Manuel. Universidad Nacional de la Patagonia "San Juan Bosco". Instituto de Biociencias de la Patagonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto de Biociencias de la Patagonia; Argentina
Fil: Hernández, Martín Alejandro. Universidad Nacional de la Patagonia "San Juan Bosco". Instituto de Biociencias de la Patagonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto de Biociencias de la Patagonia; Argentina
Fil: Lanfranconi, Mariana Patricia. Universidad Nacional de la Patagonia "San Juan Bosco". Instituto de Biociencias de la Patagonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto de Biociencias de la Patagonia; Argentina
Fil: Silva, Roxana Alejandra. Universidad Nacional de la Patagonia "San Juan Bosco". Instituto de Biociencias de la Patagonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto de Biociencias de la Patagonia; Argentina
Fil: Villalba, María Soledad. Universidad Nacional de la Patagonia "San Juan Bosco". Instituto de Biociencias de la Patagonia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto de Biociencias de la Patagonia; Argentina
description Bacteria belonging to the Rhodococcus genus are frequent components of microbial communitiesin diverse natural environments. Some rhodococcal species exhibit the outstanding ability toproduce significant amounts of triacylglycerols (TAG) (>20% of cellular dry weight) in the presenceof an excess of the carbon source and limitation of the nitrogen source. For this reason, they canbe considered as oleaginous microorganisms. As occurs as well in eukaryotic single-cell oil (SCO)producers, these bacteria possess specific physiological properties and molecular mechanisms that differentiate them from other microorganisms unable to synthesize TAG. In this review, we summarized several of the well-characterized molecular mechanisms that enable oleaginous rhodococci to produce significant amounts of SCO. Furthermore, we highlighted the ability of these microorganisms to degrade a wide range of carbon sources coupled to lipogenesis. The qualitative and quantitative oil production by rhodococci from diverse industrial wastes has also been included. Finally, we summarized the genetic and metabolic approaches applied to oleaginous rhodococci to improve SCO production. This review provides a comprehensive and integrating vision on the potential of oleaginous rhodococci to be considered as microbial biofactories for microbial oil production.
publishDate 2021
dc.date.none.fl_str_mv 2021-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/170210
Alvarez, Hector Manuel; Hernández, Martín Alejandro; Lanfranconi, Mariana Patricia; Silva, Roxana Alejandra; Villalba, María Soledad; Rhodococcus as Biofactories for Microbial Oil Production; Molecular Diversity Preservation International; Molecules; 26; 16; 8-2021; 1-27
1420-3049
CONICET Digital
CONICET
url http://hdl.handle.net/11336/170210
identifier_str_mv Alvarez, Hector Manuel; Hernández, Martín Alejandro; Lanfranconi, Mariana Patricia; Silva, Roxana Alejandra; Villalba, María Soledad; Rhodococcus as Biofactories for Microbial Oil Production; Molecular Diversity Preservation International; Molecules; 26; 16; 8-2021; 1-27
1420-3049
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.3390/molecules26164871
info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/1420-3049/26/16/4871
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Molecular Diversity Preservation International
publisher.none.fl_str_mv Molecular Diversity Preservation International
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.071171

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