A new calcium releasing nano-composite biomaterial for bone tissue engineering scaffolds

Autores
Cattalini, Juan Pablo; Garcia, J,; Boccaccini, A. R.; Lucangioli, Silvia Edith; Mouriño, Viviana Silvia Lourdes
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A biomaterial with bioactive glass nanoparticles (nBG) and Ca2+ incorporated into alginate matrix was developed. Films characterization was carried out by SEM, IR, tensile strength measurements, bioactivity assay, degradation and swelling studies. Ca2+ release from films was analyzed. Freeze-dried-scaffolds were also fabricated. Films showed the development of a homogeneous matrix and the mechanical properties were improved when nBG were incorporated. The bioactive nature of nBG containing films was confirmed by studies in simulated body fluid. Degradation was negligible and a good swelling capacity was observed. Moreover Ca2+ was released in a controlled manner. In scaffolds fabricated by freeze-drying, pores were seen to be uniform and well distributed. According to the characterization results, these composite biomaterials are attractive candidates for the fabrication of bone tissue engineering scaffolds.
Fil: Cattalini, Juan Pablo. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Garcia, J,. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Boccaccini, A. R.. Universitat Erlangen-Nuremberg; Alemania;
Fil: Lucangioli, Silvia Edith. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Química Analítica y Fisicoquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
Fil: Mouriño, Viviana Silvia Lourdes. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
Materia
Composites
Biomaterials
Films
Calcium
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/1927
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/1927
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling A new calcium releasing nano-composite biomaterial for bone tissue engineering scaffoldsCattalini, Juan PabloGarcia, J,Boccaccini, A. R.Lucangioli, Silvia EdithMouriño, Viviana Silvia LourdesCompositesBiomaterialsFilmsCalciumhttps://purl.org/becyt/ford/2.10https://purl.org/becyt/ford/2https://purl.org/becyt/ford/2.9https://purl.org/becyt/ford/2A biomaterial with bioactive glass nanoparticles (nBG) and Ca2+ incorporated into alginate matrix was developed. Films characterization was carried out by SEM, IR, tensile strength measurements, bioactivity assay, degradation and swelling studies. Ca2+ release from films was analyzed. Freeze-dried-scaffolds were also fabricated. Films showed the development of a homogeneous matrix and the mechanical properties were improved when nBG were incorporated. The bioactive nature of nBG containing films was confirmed by studies in simulated body fluid. Degradation was negligible and a good swelling capacity was observed. Moreover Ca2+ was released in a controlled manner. In scaffolds fabricated by freeze-drying, pores were seen to be uniform and well distributed. According to the characterization results, these composite biomaterials are attractive candidates for the fabrication of bone tissue engineering scaffolds.Fil: Cattalini, Juan Pablo. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Garcia, J,. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Boccaccini, A. R.. Universitat Erlangen-Nuremberg; Alemania;Fil: Lucangioli, Silvia Edith. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Química Analítica y Fisicoquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; ArgentinaFil: Mouriño, Viviana Silvia Lourdes. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; ArgentinaElsevier2013-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/1927Cattalini, Juan Pablo; Garcia, J,; Boccaccini, A. R.; Lucangioli, Silvia Edith; Mouriño, Viviana Silvia Lourdes; A new calcium releasing nano-composite biomaterial for bone tissue engineering scaffolds; Elsevier; Procedia Engineering; 59; 5-2013; 78-841877-7058eng3rd International Conference on Tissue Engineering, ICTE 2013info:eu-repo/semantics/altIdentifier/doi/doi:10.1016/j.proeng.2013.05.096info:eu-repo/semantics/altIdentifier/url/http://ac.els-cdn.com/S1877705813010102/1-s2.0-S1877705813010102-main.pdf?_tid=f9936dfa-523f-11e5-94cd-00000aacb35f&acdnat=1441287222_5427528818030452e1e337c8b2e8206cinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:03:51Zoai:ri.conicet.gov.ar:11336/1927instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:03:51.627CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv A new calcium releasing nano-composite biomaterial for bone tissue engineering scaffolds
title A new calcium releasing nano-composite biomaterial for bone tissue engineering scaffolds
spellingShingle A new calcium releasing nano-composite biomaterial for bone tissue engineering scaffolds
Cattalini, Juan Pablo
Composites
Biomaterials
Films
Calcium
title_short A new calcium releasing nano-composite biomaterial for bone tissue engineering scaffolds
title_full A new calcium releasing nano-composite biomaterial for bone tissue engineering scaffolds
title_fullStr A new calcium releasing nano-composite biomaterial for bone tissue engineering scaffolds
title_full_unstemmed A new calcium releasing nano-composite biomaterial for bone tissue engineering scaffolds
title_sort A new calcium releasing nano-composite biomaterial for bone tissue engineering scaffolds
dc.creator.none.fl_str_mv Cattalini, Juan Pablo
Garcia, J,
Boccaccini, A. R.
Lucangioli, Silvia Edith
Mouriño, Viviana Silvia Lourdes
author Cattalini, Juan Pablo
author_facet Cattalini, Juan Pablo
Garcia, J,
Boccaccini, A. R.
Lucangioli, Silvia Edith
Mouriño, Viviana Silvia Lourdes
author_role author
author2 Garcia, J,
Boccaccini, A. R.
Lucangioli, Silvia Edith
Mouriño, Viviana Silvia Lourdes
author2_role author
author
author
author
dc.subject.none.fl_str_mv Composites
Biomaterials
Films
Calcium
topic Composites
Biomaterials
Films
Calcium
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.10
https://purl.org/becyt/ford/2
https://purl.org/becyt/ford/2.9
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv A biomaterial with bioactive glass nanoparticles (nBG) and Ca2+ incorporated into alginate matrix was developed. Films characterization was carried out by SEM, IR, tensile strength measurements, bioactivity assay, degradation and swelling studies. Ca2+ release from films was analyzed. Freeze-dried-scaffolds were also fabricated. Films showed the development of a homogeneous matrix and the mechanical properties were improved when nBG were incorporated. The bioactive nature of nBG containing films was confirmed by studies in simulated body fluid. Degradation was negligible and a good swelling capacity was observed. Moreover Ca2+ was released in a controlled manner. In scaffolds fabricated by freeze-drying, pores were seen to be uniform and well distributed. According to the characterization results, these composite biomaterials are attractive candidates for the fabrication of bone tissue engineering scaffolds.
Fil: Cattalini, Juan Pablo. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Garcia, J,. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Boccaccini, A. R.. Universitat Erlangen-Nuremberg; Alemania;
Fil: Lucangioli, Silvia Edith. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Química Analítica y Fisicoquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
Fil: Mouriño, Viviana Silvia Lourdes. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
description A biomaterial with bioactive glass nanoparticles (nBG) and Ca2+ incorporated into alginate matrix was developed. Films characterization was carried out by SEM, IR, tensile strength measurements, bioactivity assay, degradation and swelling studies. Ca2+ release from films was analyzed. Freeze-dried-scaffolds were also fabricated. Films showed the development of a homogeneous matrix and the mechanical properties were improved when nBG were incorporated. The bioactive nature of nBG containing films was confirmed by studies in simulated body fluid. Degradation was negligible and a good swelling capacity was observed. Moreover Ca2+ was released in a controlled manner. In scaffolds fabricated by freeze-drying, pores were seen to be uniform and well distributed. According to the characterization results, these composite biomaterials are attractive candidates for the fabrication of bone tissue engineering scaffolds.
publishDate 2013
dc.date.none.fl_str_mv 2013-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/1927
Cattalini, Juan Pablo; Garcia, J,; Boccaccini, A. R.; Lucangioli, Silvia Edith; Mouriño, Viviana Silvia Lourdes; A new calcium releasing nano-composite biomaterial for bone tissue engineering scaffolds; Elsevier; Procedia Engineering; 59; 5-2013; 78-84
1877-7058
url http://hdl.handle.net/11336/1927
identifier_str_mv Cattalini, Juan Pablo; Garcia, J,; Boccaccini, A. R.; Lucangioli, Silvia Edith; Mouriño, Viviana Silvia Lourdes; A new calcium releasing nano-composite biomaterial for bone tissue engineering scaffolds; Elsevier; Procedia Engineering; 59; 5-2013; 78-84
1877-7058
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 3rd International Conference on Tissue Engineering, ICTE 2013
info:eu-repo/semantics/altIdentifier/doi/doi:10.1016/j.proeng.2013.05.096
info:eu-repo/semantics/altIdentifier/url/http://ac.els-cdn.com/S1877705813010102/1-s2.0-S1877705813010102-main.pdf?_tid=f9936dfa-523f-11e5-94cd-00000aacb35f&acdnat=1441287222_5427528818030452e1e337c8b2e8206c
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846781281134706688
score 13.229304

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