Primary empathy deficits in frontotemporal dementia

Autores
Báez Buitrago, Sandra Jimena; Manes, Facundo Francisco; Huepe, David; Torralva, Teresa; Fiorentino, Natalia; Richter, Fabian; Huepe-Artigas, Daniela; Ferrari, Jesica Celeste; Montañes, Patricia; Reyes, Pablo; Matallana, Diana; Vigliecca, Nora Silvana; Decety, Jean; Ibanez Barassi, Agustin Mariano
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Loss of empathy is an early central symptom and diagnostic criterion of the behavioral variant frontotemporal dementia (bvFTD). Although changes in empathy are evident and strongly affect the social functioning of bvFTD patients, few studies have directly investigated this issue by means of experimental paradigms. The current study assessed multiple components of empathy (affective, cognitive and moral) in bvFTD patients. We also explored whether the loss of empathy constitutes a primary deficit of bvFTD or whether it is explained by impairments in executive functions (EF) or other social cognition domains. Thirty-seven bvFTD patients with early/mild stages of the disease and 30 healthy control participants were assessed with a task that involves the perception of intentional and accidental harm. Participants were also evaluated on emotion recognition, theory of mind (ToM), social norms knowledge and several EF domains. BvFTD patients presented deficits in affective, cognitive and moral aspects of empathy. However, empathic concern was the only aspect primarily affected in bvFTD that was neither related nor explained by deficits in EF or other social cognition domains. Deficits in the cognitive and moral aspects of empathy seem to depend on EF, emotion recognition and ToM. Our findings highlight the importance of using tasks depicting real-life social scenarios because of their greater sensitivity in the assessment of bvFTD. Moreover, our results contribute to the understanding of primary and intrinsic empathy deficits of bvFTD and have important theoretical and clinical implications.
Fil: Báez Buitrago, Sandra Jimena. Universidad Diego Portales; Chile. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; Argentina. Instituto de Neurología Cognitiva. Laboratorio de Psicología Experimental y Neurociencia; Argentina
Fil: Manes, Facundo Francisco. Universidad Diego Portales; Chile. Australian Research Council Centre Of Excellence In Cognition And Its Disorders; Australia. Universidad Favaloro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Neurología Cognitiva; Argentina
Fil: Huepe, David. Universidad Diego Portales; Chile
Fil: Torralva, Teresa. Universidad Favaloro; Argentina
Fil: Fiorentino, Natalia. Universidad Favaloro; Argentina. Universidad Diego Portales; Chile
Fil: Richter, Fabian. Universitat zu Köln; Alemania
Fil: Huepe-Artigas, Daniela. Universidad Diego Portales; Chile
Fil: Ferrari, Jesica Celeste. Universidad Favaloro; Argentina
Fil: Montañes, Patricia. Pontificia Universidad Javeriana; Colombia. Universidad Nacional de Colombia; Colombia
Fil: Reyes, Pablo. Pontificia Universidad Javeriana; Colombia
Fil: Matallana, Diana. Pontificia Universidad Javeriana; Colombia
Fil: Vigliecca, Nora Silvana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Humanidades. Universidad Nacional de Córdoba. Instituto de Humanidades; Argentina
Fil: Decety, Jean. University of Chicago; Estados Unidos
Fil: Ibanez Barassi, Agustin Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; Argentina. Universidad Diego Portales; Chile. Universidad de San Andrés; Argentina
Materia
BEHAVIORAL VARIANT OF FRONTOTEMPORAL DEMENTIA
EMPATHY
EMPATHIC CONCERN
SOCIAL COGNITION
EXECUTIVE FUNCTIONS
MORAL JUDGMENT
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/113944
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Primary empathy deficits in frontotemporal dementiaBáez Buitrago, Sandra JimenaManes, Facundo FranciscoHuepe, DavidTorralva, TeresaFiorentino, NataliaRichter, FabianHuepe-Artigas, DanielaFerrari, Jesica CelesteMontañes, PatriciaReyes, PabloMatallana, DianaVigliecca, Nora SilvanaDecety, JeanIbanez Barassi, Agustin MarianoBEHAVIORAL VARIANT OF FRONTOTEMPORAL DEMENTIAEMPATHYEMPATHIC CONCERNSOCIAL COGNITIONEXECUTIVE FUNCTIONSMORAL JUDGMENThttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Loss of empathy is an early central symptom and diagnostic criterion of the behavioral variant frontotemporal dementia (bvFTD). Although changes in empathy are evident and strongly affect the social functioning of bvFTD patients, few studies have directly investigated this issue by means of experimental paradigms. The current study assessed multiple components of empathy (affective, cognitive and moral) in bvFTD patients. We also explored whether the loss of empathy constitutes a primary deficit of bvFTD or whether it is explained by impairments in executive functions (EF) or other social cognition domains. Thirty-seven bvFTD patients with early/mild stages of the disease and 30 healthy control participants were assessed with a task that involves the perception of intentional and accidental harm. Participants were also evaluated on emotion recognition, theory of mind (ToM), social norms knowledge and several EF domains. BvFTD patients presented deficits in affective, cognitive and moral aspects of empathy. However, empathic concern was the only aspect primarily affected in bvFTD that was neither related nor explained by deficits in EF or other social cognition domains. Deficits in the cognitive and moral aspects of empathy seem to depend on EF, emotion recognition and ToM. Our findings highlight the importance of using tasks depicting real-life social scenarios because of their greater sensitivity in the assessment of bvFTD. Moreover, our results contribute to the understanding of primary and intrinsic empathy deficits of bvFTD and have important theoretical and clinical implications.Fil: Báez Buitrago, Sandra Jimena. Universidad Diego Portales; Chile. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; Argentina. Instituto de Neurología Cognitiva. Laboratorio de Psicología Experimental y Neurociencia; ArgentinaFil: Manes, Facundo Francisco. Universidad Diego Portales; Chile. Australian Research Council Centre Of Excellence In Cognition And Its Disorders; Australia. Universidad Favaloro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Neurología Cognitiva; ArgentinaFil: Huepe, David. Universidad Diego Portales; ChileFil: Torralva, Teresa. Universidad Favaloro; ArgentinaFil: Fiorentino, Natalia. Universidad Favaloro; Argentina. Universidad Diego Portales; ChileFil: Richter, Fabian. Universitat zu Köln; AlemaniaFil: Huepe-Artigas, Daniela. Universidad Diego Portales; ChileFil: Ferrari, Jesica Celeste. Universidad Favaloro; ArgentinaFil: Montañes, Patricia. Pontificia Universidad Javeriana; Colombia. Universidad Nacional de Colombia; ColombiaFil: Reyes, Pablo. Pontificia Universidad Javeriana; ColombiaFil: Matallana, Diana. Pontificia Universidad Javeriana; ColombiaFil: Vigliecca, Nora Silvana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Humanidades. Universidad Nacional de Córdoba. Instituto de Humanidades; ArgentinaFil: Decety, Jean. University of Chicago; Estados UnidosFil: Ibanez Barassi, Agustin Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; Argentina. Universidad Diego Portales; Chile. Universidad de San Andrés; ArgentinaFrontiers Research Foundation2014-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/113944Báez Buitrago, Sandra Jimena; Manes, Facundo Francisco; Huepe, David; Torralva, Teresa; Fiorentino, Natalia; et al.; Primary empathy deficits in frontotemporal dementia; Frontiers Research Foundation; Frontiers in Aging Neuroscience; 6; 262; 10-2014; 1-111663-4365CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00262/abstractinfo:eu-repo/semantics/altIdentifier/doi/10.3389/fnagi.2014.00262info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:52:16Zoai:ri.conicet.gov.ar:11336/113944instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:52:17.068CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Primary empathy deficits in frontotemporal dementia
title Primary empathy deficits in frontotemporal dementia
spellingShingle Primary empathy deficits in frontotemporal dementia
Báez Buitrago, Sandra Jimena
BEHAVIORAL VARIANT OF FRONTOTEMPORAL DEMENTIA
EMPATHY
EMPATHIC CONCERN
SOCIAL COGNITION
EXECUTIVE FUNCTIONS
MORAL JUDGMENT
title_short Primary empathy deficits in frontotemporal dementia
title_full Primary empathy deficits in frontotemporal dementia
title_fullStr Primary empathy deficits in frontotemporal dementia
title_full_unstemmed Primary empathy deficits in frontotemporal dementia
title_sort Primary empathy deficits in frontotemporal dementia
dc.creator.none.fl_str_mv Báez Buitrago, Sandra Jimena
Manes, Facundo Francisco
Huepe, David
Torralva, Teresa
Fiorentino, Natalia
Richter, Fabian
Huepe-Artigas, Daniela
Ferrari, Jesica Celeste
Montañes, Patricia
Reyes, Pablo
Matallana, Diana
Vigliecca, Nora Silvana
Decety, Jean
Ibanez Barassi, Agustin Mariano
author Báez Buitrago, Sandra Jimena
author_facet Báez Buitrago, Sandra Jimena
Manes, Facundo Francisco
Huepe, David
Torralva, Teresa
Fiorentino, Natalia
Richter, Fabian
Huepe-Artigas, Daniela
Ferrari, Jesica Celeste
Montañes, Patricia
Reyes, Pablo
Matallana, Diana
Vigliecca, Nora Silvana
Decety, Jean
Ibanez Barassi, Agustin Mariano
author_role author
author2 Manes, Facundo Francisco
Huepe, David
Torralva, Teresa
Fiorentino, Natalia
Richter, Fabian
Huepe-Artigas, Daniela
Ferrari, Jesica Celeste
Montañes, Patricia
Reyes, Pablo
Matallana, Diana
Vigliecca, Nora Silvana
Decety, Jean
Ibanez Barassi, Agustin Mariano
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv BEHAVIORAL VARIANT OF FRONTOTEMPORAL DEMENTIA
EMPATHY
EMPATHIC CONCERN
SOCIAL COGNITION
EXECUTIVE FUNCTIONS
MORAL JUDGMENT
topic BEHAVIORAL VARIANT OF FRONTOTEMPORAL DEMENTIA
EMPATHY
EMPATHIC CONCERN
SOCIAL COGNITION
EXECUTIVE FUNCTIONS
MORAL JUDGMENT
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Loss of empathy is an early central symptom and diagnostic criterion of the behavioral variant frontotemporal dementia (bvFTD). Although changes in empathy are evident and strongly affect the social functioning of bvFTD patients, few studies have directly investigated this issue by means of experimental paradigms. The current study assessed multiple components of empathy (affective, cognitive and moral) in bvFTD patients. We also explored whether the loss of empathy constitutes a primary deficit of bvFTD or whether it is explained by impairments in executive functions (EF) or other social cognition domains. Thirty-seven bvFTD patients with early/mild stages of the disease and 30 healthy control participants were assessed with a task that involves the perception of intentional and accidental harm. Participants were also evaluated on emotion recognition, theory of mind (ToM), social norms knowledge and several EF domains. BvFTD patients presented deficits in affective, cognitive and moral aspects of empathy. However, empathic concern was the only aspect primarily affected in bvFTD that was neither related nor explained by deficits in EF or other social cognition domains. Deficits in the cognitive and moral aspects of empathy seem to depend on EF, emotion recognition and ToM. Our findings highlight the importance of using tasks depicting real-life social scenarios because of their greater sensitivity in the assessment of bvFTD. Moreover, our results contribute to the understanding of primary and intrinsic empathy deficits of bvFTD and have important theoretical and clinical implications.
Fil: Báez Buitrago, Sandra Jimena. Universidad Diego Portales; Chile. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; Argentina. Instituto de Neurología Cognitiva. Laboratorio de Psicología Experimental y Neurociencia; Argentina
Fil: Manes, Facundo Francisco. Universidad Diego Portales; Chile. Australian Research Council Centre Of Excellence In Cognition And Its Disorders; Australia. Universidad Favaloro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Neurología Cognitiva; Argentina
Fil: Huepe, David. Universidad Diego Portales; Chile
Fil: Torralva, Teresa. Universidad Favaloro; Argentina
Fil: Fiorentino, Natalia. Universidad Favaloro; Argentina. Universidad Diego Portales; Chile
Fil: Richter, Fabian. Universitat zu Köln; Alemania
Fil: Huepe-Artigas, Daniela. Universidad Diego Portales; Chile
Fil: Ferrari, Jesica Celeste. Universidad Favaloro; Argentina
Fil: Montañes, Patricia. Pontificia Universidad Javeriana; Colombia. Universidad Nacional de Colombia; Colombia
Fil: Reyes, Pablo. Pontificia Universidad Javeriana; Colombia
Fil: Matallana, Diana. Pontificia Universidad Javeriana; Colombia
Fil: Vigliecca, Nora Silvana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Humanidades. Universidad Nacional de Córdoba. Instituto de Humanidades; Argentina
Fil: Decety, Jean. University of Chicago; Estados Unidos
Fil: Ibanez Barassi, Agustin Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; Argentina. Universidad Diego Portales; Chile. Universidad de San Andrés; Argentina
description Loss of empathy is an early central symptom and diagnostic criterion of the behavioral variant frontotemporal dementia (bvFTD). Although changes in empathy are evident and strongly affect the social functioning of bvFTD patients, few studies have directly investigated this issue by means of experimental paradigms. The current study assessed multiple components of empathy (affective, cognitive and moral) in bvFTD patients. We also explored whether the loss of empathy constitutes a primary deficit of bvFTD or whether it is explained by impairments in executive functions (EF) or other social cognition domains. Thirty-seven bvFTD patients with early/mild stages of the disease and 30 healthy control participants were assessed with a task that involves the perception of intentional and accidental harm. Participants were also evaluated on emotion recognition, theory of mind (ToM), social norms knowledge and several EF domains. BvFTD patients presented deficits in affective, cognitive and moral aspects of empathy. However, empathic concern was the only aspect primarily affected in bvFTD that was neither related nor explained by deficits in EF or other social cognition domains. Deficits in the cognitive and moral aspects of empathy seem to depend on EF, emotion recognition and ToM. Our findings highlight the importance of using tasks depicting real-life social scenarios because of their greater sensitivity in the assessment of bvFTD. Moreover, our results contribute to the understanding of primary and intrinsic empathy deficits of bvFTD and have important theoretical and clinical implications.
publishDate 2014
dc.date.none.fl_str_mv 2014-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/113944
Báez Buitrago, Sandra Jimena; Manes, Facundo Francisco; Huepe, David; Torralva, Teresa; Fiorentino, Natalia; et al.; Primary empathy deficits in frontotemporal dementia; Frontiers Research Foundation; Frontiers in Aging Neuroscience; 6; 262; 10-2014; 1-11
1663-4365
CONICET Digital
CONICET
url http://hdl.handle.net/11336/113944
identifier_str_mv Báez Buitrago, Sandra Jimena; Manes, Facundo Francisco; Huepe, David; Torralva, Teresa; Fiorentino, Natalia; et al.; Primary empathy deficits in frontotemporal dementia; Frontiers Research Foundation; Frontiers in Aging Neuroscience; 6; 262; 10-2014; 1-11
1663-4365
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00262/abstract
info:eu-repo/semantics/altIdentifier/doi/10.3389/fnagi.2014.00262
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Frontiers Research Foundation
publisher.none.fl_str_mv Frontiers Research Foundation
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
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instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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