Does cognitive remediation improve the functional outcomes of bipolar disorder individuals?

Autores
Samame, Cecilia
Año de publicación
2022
Idioma
inglés
Tipo de recurso
documento de conferencia
Estado
versión publicada
Descripción
Introduction: Bipolar disorder (BD) is associated with significant impairments in different areas of everyday functioning. Numerous studies have documented that, even during euthymia, about 70% of those affected present with cognitive impairments. These deficits are of variable magnitude and involve a number of domains, such as episodic memory, attention, and different aspects of executive functioning. In the last fifteen years, neuropsychological aspects of BD have gained increasing interest based on the consistent evidence of a significant negative correlation between cognitive deficits and functional adjustment. These considerations are particularly relevant since a significant percentage of affected individuals exhibit suboptimal general functioning despite receiving adequate pharmacological treatment. In this context, cognitive remediation (CR) hasbeen proposed as an emergent treatment that could help manage some manifestations of BD that pharmacological treatments fail to resolve. Within this context, the current study was conducted with the aim of exploring the efficacy of CR to improve functional outcomes in BD patients.Method: Meta-analysis of randomized controlled trials published up to February, 2022 that explore the effects of CR on the functional outcomes of BD individuals by means of standardized scales.Results: Five studies, with a total of 130 patients under treatment with CR and 125 controls were included. No significant between-group differences were found for longitudinal change in the scores obtained on scales assessing general functioning. Conclusion: The evidence available to date suggests that CR may not be an efficacious treatment for improving the functional outcomesof BD patients. Directions for future research are proposed.
Fil: Samame, Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Centro Interdisciplinario de Investigaciones en Psicología Matemática y Experimental Dr. Horacio J. A. Rimoldi; Argentina
24th Annual Conference of the International Society for Bipolar Disorders
Estados Unidos
International Society for Bipolar Disorders
Materia
Bipolar disorders
Cognitive remediation
Efficacy
Meta-analysis
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/216496
Acceder
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spelling Does cognitive remediation improve the functional outcomes of bipolar disorder individuals?Samame, CeciliaBipolar disordersCognitive remediationEfficacyMeta-analysishttps://purl.org/becyt/ford/5.1https://purl.org/becyt/ford/5Introduction: Bipolar disorder (BD) is associated with significant impairments in different areas of everyday functioning. Numerous studies have documented that, even during euthymia, about 70% of those affected present with cognitive impairments. These deficits are of variable magnitude and involve a number of domains, such as episodic memory, attention, and different aspects of executive functioning. In the last fifteen years, neuropsychological aspects of BD have gained increasing interest based on the consistent evidence of a significant negative correlation between cognitive deficits and functional adjustment. These considerations are particularly relevant since a significant percentage of affected individuals exhibit suboptimal general functioning despite receiving adequate pharmacological treatment. In this context, cognitive remediation (CR) hasbeen proposed as an emergent treatment that could help manage some manifestations of BD that pharmacological treatments fail to resolve. Within this context, the current study was conducted with the aim of exploring the efficacy of CR to improve functional outcomes in BD patients.Method: Meta-analysis of randomized controlled trials published up to February, 2022 that explore the effects of CR on the functional outcomes of BD individuals by means of standardized scales.Results: Five studies, with a total of 130 patients under treatment with CR and 125 controls were included. No significant between-group differences were found for longitudinal change in the scores obtained on scales assessing general functioning. Conclusion: The evidence available to date suggests that CR may not be an efficacious treatment for improving the functional outcomesof BD patients. Directions for future research are proposed.Fil: Samame, Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Centro Interdisciplinario de Investigaciones en Psicología Matemática y Experimental Dr. Horacio J. A. Rimoldi; Argentina24th Annual Conference of the International Society for Bipolar DisordersEstados UnidosInternational Society for Bipolar DisordersWiley2022info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectCongresoJournalhttp://purl.org/coar/resource_type/c_5794info:ar-repo/semantics/documentoDeConferenciaapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/216496Does cognitive remediation improve the functional outcomes of bipolar disorder individuals?; 24th Annual Conference of the International Society for Bipolar Disorders; Estados Unidos; 2022; 52-521398-56471399-5618CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/toc/13995618/2022/24/S1Internacionalinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:10:22Zoai:ri.conicet.gov.ar:11336/216496instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:10:22.795CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Does cognitive remediation improve the functional outcomes of bipolar disorder individuals?
title Does cognitive remediation improve the functional outcomes of bipolar disorder individuals?
spellingShingle Does cognitive remediation improve the functional outcomes of bipolar disorder individuals?
Samame, Cecilia
Bipolar disorders
Cognitive remediation
Efficacy
Meta-analysis
title_short Does cognitive remediation improve the functional outcomes of bipolar disorder individuals?
title_full Does cognitive remediation improve the functional outcomes of bipolar disorder individuals?
title_fullStr Does cognitive remediation improve the functional outcomes of bipolar disorder individuals?
title_full_unstemmed Does cognitive remediation improve the functional outcomes of bipolar disorder individuals?
title_sort Does cognitive remediation improve the functional outcomes of bipolar disorder individuals?
dc.creator.none.fl_str_mv Samame, Cecilia
author Samame, Cecilia
author_facet Samame, Cecilia
author_role author
dc.subject.none.fl_str_mv Bipolar disorders
Cognitive remediation
Efficacy
Meta-analysis
topic Bipolar disorders
Cognitive remediation
Efficacy
Meta-analysis
purl_subject.fl_str_mv https://purl.org/becyt/ford/5.1
https://purl.org/becyt/ford/5
dc.description.none.fl_txt_mv Introduction: Bipolar disorder (BD) is associated with significant impairments in different areas of everyday functioning. Numerous studies have documented that, even during euthymia, about 70% of those affected present with cognitive impairments. These deficits are of variable magnitude and involve a number of domains, such as episodic memory, attention, and different aspects of executive functioning. In the last fifteen years, neuropsychological aspects of BD have gained increasing interest based on the consistent evidence of a significant negative correlation between cognitive deficits and functional adjustment. These considerations are particularly relevant since a significant percentage of affected individuals exhibit suboptimal general functioning despite receiving adequate pharmacological treatment. In this context, cognitive remediation (CR) hasbeen proposed as an emergent treatment that could help manage some manifestations of BD that pharmacological treatments fail to resolve. Within this context, the current study was conducted with the aim of exploring the efficacy of CR to improve functional outcomes in BD patients.Method: Meta-analysis of randomized controlled trials published up to February, 2022 that explore the effects of CR on the functional outcomes of BD individuals by means of standardized scales.Results: Five studies, with a total of 130 patients under treatment with CR and 125 controls were included. No significant between-group differences were found for longitudinal change in the scores obtained on scales assessing general functioning. Conclusion: The evidence available to date suggests that CR may not be an efficacious treatment for improving the functional outcomesof BD patients. Directions for future research are proposed.
Fil: Samame, Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Centro Interdisciplinario de Investigaciones en Psicología Matemática y Experimental Dr. Horacio J. A. Rimoldi; Argentina
24th Annual Conference of the International Society for Bipolar Disorders
Estados Unidos
International Society for Bipolar Disorders
description Introduction: Bipolar disorder (BD) is associated with significant impairments in different areas of everyday functioning. Numerous studies have documented that, even during euthymia, about 70% of those affected present with cognitive impairments. These deficits are of variable magnitude and involve a number of domains, such as episodic memory, attention, and different aspects of executive functioning. In the last fifteen years, neuropsychological aspects of BD have gained increasing interest based on the consistent evidence of a significant negative correlation between cognitive deficits and functional adjustment. These considerations are particularly relevant since a significant percentage of affected individuals exhibit suboptimal general functioning despite receiving adequate pharmacological treatment. In this context, cognitive remediation (CR) hasbeen proposed as an emergent treatment that could help manage some manifestations of BD that pharmacological treatments fail to resolve. Within this context, the current study was conducted with the aim of exploring the efficacy of CR to improve functional outcomes in BD patients.Method: Meta-analysis of randomized controlled trials published up to February, 2022 that explore the effects of CR on the functional outcomes of BD individuals by means of standardized scales.Results: Five studies, with a total of 130 patients under treatment with CR and 125 controls were included. No significant between-group differences were found for longitudinal change in the scores obtained on scales assessing general functioning. Conclusion: The evidence available to date suggests that CR may not be an efficacious treatment for improving the functional outcomesof BD patients. Directions for future research are proposed.
publishDate 2022
dc.date.none.fl_str_mv 2022
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/conferenceObject
Congreso
Journal
http://purl.org/coar/resource_type/c_5794
info:ar-repo/semantics/documentoDeConferencia
status_str publishedVersion
format conferenceObject
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/216496
Does cognitive remediation improve the functional outcomes of bipolar disorder individuals?; 24th Annual Conference of the International Society for Bipolar Disorders; Estados Unidos; 2022; 52-52
1398-5647
1399-5618
CONICET Digital
CONICET
url http://hdl.handle.net/11336/216496
identifier_str_mv Does cognitive remediation improve the functional outcomes of bipolar disorder individuals?; 24th Annual Conference of the International Society for Bipolar Disorders; Estados Unidos; 2022; 52-52
1398-5647
1399-5618
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/toc/13995618/2022/24/S1
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.coverage.none.fl_str_mv Internacional
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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