Seizures Induces Hypoxia and Hypoxia Induces Seizures: A Perverse Relationship that Increases the Risk of SUDEP

Autores
Auzmendi, Jerónimo Andrés; Lazarowski, Alberto Jorge
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
He uttered a cry and was seen to be rubbing his hands together. His pulse wasimmediately examined for but was not palpable.Hypoxia is a biological stimulus capable of promoting both rescue and survivalmechanisms, as well as triggering a sequence of irreversible events that lead to deathof cell, tissue and even individual. Brain and heart functions depend critically onadequate energy supply and they are highly susceptible to hypoxic conditions.Adequate oxygen supply is needed for the brain and heart to metabolize glucose asits major energy source. But how many type of hypoxia we know, and how muchsevere is the hypoxic condition, when more than one type of hypoxia aresimultaneously acting. Four types of hypoxia are distinguished in medicine: α- thehypoxemic hypoxia, due to a decrease in the amount of breathable oxygen orcardiopulmonary failure, b- the anemic hypoxia related with decreased amount offunctional hemoglobin, c- the stagnant hypoxia, secondary to reduced or unevenlydistributed flow of blood distribution to the tissues, and mainly result from heartdisease that impairs the circulation; and d- the histotoxic hypoxia, in which the tissuecells are poisoned and are therefore unable to make proper use of oxygen.
Fil: Auzmendi, Jerónimo Andrés. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
Fil: Lazarowski, Alberto Jorge. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina
Materia
SEIZURES
HYPOXIA
SUDEP
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/134927
Acceder
id CONICETDig_c75f87684a5c64ba2eae3a0d80b93ed1
oai_identifier_str oai:ri.conicet.gov.ar:11336/134927
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Seizures Induces Hypoxia and Hypoxia Induces Seizures: A Perverse Relationship that Increases the Risk of SUDEPAuzmendi, Jerónimo AndrésLazarowski, Alberto JorgeSEIZURESHYPOXIASUDEPhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3He uttered a cry and was seen to be rubbing his hands together. His pulse wasimmediately examined for but was not palpable.Hypoxia is a biological stimulus capable of promoting both rescue and survivalmechanisms, as well as triggering a sequence of irreversible events that lead to deathof cell, tissue and even individual. Brain and heart functions depend critically onadequate energy supply and they are highly susceptible to hypoxic conditions.Adequate oxygen supply is needed for the brain and heart to metabolize glucose asits major energy source. But how many type of hypoxia we know, and how muchsevere is the hypoxic condition, when more than one type of hypoxia aresimultaneously acting. Four types of hypoxia are distinguished in medicine: α- thehypoxemic hypoxia, due to a decrease in the amount of breathable oxygen orcardiopulmonary failure, b- the anemic hypoxia related with decreased amount offunctional hemoglobin, c- the stagnant hypoxia, secondary to reduced or unevenlydistributed flow of blood distribution to the tissues, and mainly result from heartdisease that impairs the circulation; and d- the histotoxic hypoxia, in which the tissuecells are poisoned and are therefore unable to make proper use of oxygen.Fil: Auzmendi, Jerónimo Andrés. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; ArgentinaFil: Lazarowski, Alberto Jorge. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; ArgentinaScientific Literature2020-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/134927Auzmendi, Jerónimo Andrés; Lazarowski, Alberto Jorge; Seizures Induces Hypoxia and Hypoxia Induces Seizures: A Perverse Relationship that Increases the Risk of SUDEP; Scientific Literature; Neurological Disorders & Epilepsy Journal; 10-2020; 1-62349-5014CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://scientificliterature.org/Neurologicaldisorders/Neurologicaldisorders-20-135.pdfinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:36:10Zoai:ri.conicet.gov.ar:11336/134927instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:36:11.119CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Seizures Induces Hypoxia and Hypoxia Induces Seizures: A Perverse Relationship that Increases the Risk of SUDEP
title Seizures Induces Hypoxia and Hypoxia Induces Seizures: A Perverse Relationship that Increases the Risk of SUDEP
spellingShingle Seizures Induces Hypoxia and Hypoxia Induces Seizures: A Perverse Relationship that Increases the Risk of SUDEP
Auzmendi, Jerónimo Andrés
SEIZURES
HYPOXIA
SUDEP
title_short Seizures Induces Hypoxia and Hypoxia Induces Seizures: A Perverse Relationship that Increases the Risk of SUDEP
title_full Seizures Induces Hypoxia and Hypoxia Induces Seizures: A Perverse Relationship that Increases the Risk of SUDEP
title_fullStr Seizures Induces Hypoxia and Hypoxia Induces Seizures: A Perverse Relationship that Increases the Risk of SUDEP
title_full_unstemmed Seizures Induces Hypoxia and Hypoxia Induces Seizures: A Perverse Relationship that Increases the Risk of SUDEP
title_sort Seizures Induces Hypoxia and Hypoxia Induces Seizures: A Perverse Relationship that Increases the Risk of SUDEP
dc.creator.none.fl_str_mv Auzmendi, Jerónimo Andrés
Lazarowski, Alberto Jorge
author Auzmendi, Jerónimo Andrés
author_facet Auzmendi, Jerónimo Andrés
Lazarowski, Alberto Jorge
author_role author
author2 Lazarowski, Alberto Jorge
author2_role author
dc.subject.none.fl_str_mv SEIZURES
HYPOXIA
SUDEP
topic SEIZURES
HYPOXIA
SUDEP
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv He uttered a cry and was seen to be rubbing his hands together. His pulse wasimmediately examined for but was not palpable.Hypoxia is a biological stimulus capable of promoting both rescue and survivalmechanisms, as well as triggering a sequence of irreversible events that lead to deathof cell, tissue and even individual. Brain and heart functions depend critically onadequate energy supply and they are highly susceptible to hypoxic conditions.Adequate oxygen supply is needed for the brain and heart to metabolize glucose asits major energy source. But how many type of hypoxia we know, and how muchsevere is the hypoxic condition, when more than one type of hypoxia aresimultaneously acting. Four types of hypoxia are distinguished in medicine: α- thehypoxemic hypoxia, due to a decrease in the amount of breathable oxygen orcardiopulmonary failure, b- the anemic hypoxia related with decreased amount offunctional hemoglobin, c- the stagnant hypoxia, secondary to reduced or unevenlydistributed flow of blood distribution to the tissues, and mainly result from heartdisease that impairs the circulation; and d- the histotoxic hypoxia, in which the tissuecells are poisoned and are therefore unable to make proper use of oxygen.
Fil: Auzmendi, Jerónimo Andrés. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
Fil: Lazarowski, Alberto Jorge. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina
description He uttered a cry and was seen to be rubbing his hands together. His pulse wasimmediately examined for but was not palpable.Hypoxia is a biological stimulus capable of promoting both rescue and survivalmechanisms, as well as triggering a sequence of irreversible events that lead to deathof cell, tissue and even individual. Brain and heart functions depend critically onadequate energy supply and they are highly susceptible to hypoxic conditions.Adequate oxygen supply is needed for the brain and heart to metabolize glucose asits major energy source. But how many type of hypoxia we know, and how muchsevere is the hypoxic condition, when more than one type of hypoxia aresimultaneously acting. Four types of hypoxia are distinguished in medicine: α- thehypoxemic hypoxia, due to a decrease in the amount of breathable oxygen orcardiopulmonary failure, b- the anemic hypoxia related with decreased amount offunctional hemoglobin, c- the stagnant hypoxia, secondary to reduced or unevenlydistributed flow of blood distribution to the tissues, and mainly result from heartdisease that impairs the circulation; and d- the histotoxic hypoxia, in which the tissuecells are poisoned and are therefore unable to make proper use of oxygen.
publishDate 2020
dc.date.none.fl_str_mv 2020-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/134927
Auzmendi, Jerónimo Andrés; Lazarowski, Alberto Jorge; Seizures Induces Hypoxia and Hypoxia Induces Seizures: A Perverse Relationship that Increases the Risk of SUDEP; Scientific Literature; Neurological Disorders & Epilepsy Journal; 10-2020; 1-6
2349-5014
CONICET Digital
CONICET
url http://hdl.handle.net/11336/134927
identifier_str_mv Auzmendi, Jerónimo Andrés; Lazarowski, Alberto Jorge; Seizures Induces Hypoxia and Hypoxia Induces Seizures: A Perverse Relationship that Increases the Risk of SUDEP; Scientific Literature; Neurological Disorders & Epilepsy Journal; 10-2020; 1-6
2349-5014
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://scientificliterature.org/Neurologicaldisorders/Neurologicaldisorders-20-135.pdf
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Scientific Literature
publisher.none.fl_str_mv Scientific Literature
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844613132763267072
score 13.070432

Publicaciones similares