Exaggerated interventricular dependence among patients with pectus excavatum: Combined assessment with cardiac MRI and Chest CT

Autores
Deviggiano, Alejandro; Vallejos, Javier; Vina, Natalia; Martinez Ferro, Marcelo; Bellia Munzon, Gaston; Carrascosa, Patricia; Rodriguez Granillo, Gaston Alfredo
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
OBJECTIVE. We sought to explore whether patients with pectus excavatum have exaggerated interventricular dependence and to evaluate the impact of the malformation severity (assessed on CT) on both anatomic and functional cardiac parameters (assessed on cardiac MRI). SUBJECTS AND METHODS. The current study involved consecutive patients with a diagnosis of pectus excavatum who were referred to undergo cardiac MRI and chest CT to establish surgical candidacy or to define treatment strategies. RESULTS. Sixty-two patients with pectus excavatum underwent cardiac MRI and chest CT. Fifty (81%) patients were male, and the median age was 17.5 years (range, 14.0-23.0 years). Forty-seven (76%) patients had evidence of right ventricular compression. The left ventricle showed a significantly decreased end-diastolic volume (inspiration vs expiration: 70.4 ± 11.6 vs 76.1 ± 13.7 mL/m2, respectively; p = 0.01) and a significantly higher eccentricity index (1.52 ± 0.2 vs 1.20 ± 0.1, p < 0.0001) during inspiration than during expiration. The median respiratory-related septal excursion was 8.1% (interquartile range, 5.1-11.7%). Patients with pericardial effusion showed a significantly higher pectus excavatum severity index than patients without pericardial effusion (6.3 ± 3.4 vs 4.4 ± 1.3, respectively; p = 0.003). Patients with a relative septal excursion equal to or larger than 11.8% showed a significantly higher pectus excavatum severity index than patients with a relative septal excursion of less than 11.8% (6.3 ± 2.6 vs 4.7 ± 2.4, respectively; p = 0.05). CONCLUSION. In this study, patients with pectus excavatum showed significant alterations of cardiac morphology and function that were related to the deformation severity and that manifest as an exaggerated interventricular dependence.
Fil: Deviggiano, Alejandro. Diagnostico Maipu; Argentina
Fil: Vallejos, Javier. Diagnostico Maipu; Argentina
Fil: Vina, Natalia. Diagnostico Maipu; Argentina
Fil: Martinez Ferro, Marcelo. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); Argentina
Fil: Bellia Munzon, Gaston. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); Argentina
Fil: Carrascosa, Patricia. Diagnostico Maipu; Argentina
Fil: Rodriguez Granillo, Gaston Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Diagnostico Maipu; Argentina
Materia
CHEST
CT
MRI
THORACIC MALFORMATION
THORACIC SURGERY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/66971
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/66971
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Exaggerated interventricular dependence among patients with pectus excavatum: Combined assessment with cardiac MRI and Chest CTDeviggiano, AlejandroVallejos, JavierVina, NataliaMartinez Ferro, MarceloBellia Munzon, GastonCarrascosa, PatriciaRodriguez Granillo, Gaston AlfredoCHESTCTMRITHORACIC MALFORMATIONTHORACIC SURGERYhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3OBJECTIVE. We sought to explore whether patients with pectus excavatum have exaggerated interventricular dependence and to evaluate the impact of the malformation severity (assessed on CT) on both anatomic and functional cardiac parameters (assessed on cardiac MRI). SUBJECTS AND METHODS. The current study involved consecutive patients with a diagnosis of pectus excavatum who were referred to undergo cardiac MRI and chest CT to establish surgical candidacy or to define treatment strategies. RESULTS. Sixty-two patients with pectus excavatum underwent cardiac MRI and chest CT. Fifty (81%) patients were male, and the median age was 17.5 years (range, 14.0-23.0 years). Forty-seven (76%) patients had evidence of right ventricular compression. The left ventricle showed a significantly decreased end-diastolic volume (inspiration vs expiration: 70.4 ± 11.6 vs 76.1 ± 13.7 mL/m2, respectively; p = 0.01) and a significantly higher eccentricity index (1.52 ± 0.2 vs 1.20 ± 0.1, p < 0.0001) during inspiration than during expiration. The median respiratory-related septal excursion was 8.1% (interquartile range, 5.1-11.7%). Patients with pericardial effusion showed a significantly higher pectus excavatum severity index than patients without pericardial effusion (6.3 ± 3.4 vs 4.4 ± 1.3, respectively; p = 0.003). Patients with a relative septal excursion equal to or larger than 11.8% showed a significantly higher pectus excavatum severity index than patients with a relative septal excursion of less than 11.8% (6.3 ± 2.6 vs 4.7 ± 2.4, respectively; p = 0.05). CONCLUSION. In this study, patients with pectus excavatum showed significant alterations of cardiac morphology and function that were related to the deformation severity and that manifest as an exaggerated interventricular dependence.Fil: Deviggiano, Alejandro. Diagnostico Maipu; ArgentinaFil: Vallejos, Javier. Diagnostico Maipu; ArgentinaFil: Vina, Natalia. Diagnostico Maipu; ArgentinaFil: Martinez Ferro, Marcelo. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); ArgentinaFil: Bellia Munzon, Gaston. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); ArgentinaFil: Carrascosa, Patricia. Diagnostico Maipu; ArgentinaFil: Rodriguez Granillo, Gaston Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Diagnostico Maipu; ArgentinaAmerican Roentgen Ray Society2017-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/66971Deviggiano, Alejandro; Vallejos, Javier; Vina, Natalia; Martinez Ferro, Marcelo; Bellia Munzon, Gaston; et al.; Exaggerated interventricular dependence among patients with pectus excavatum: Combined assessment with cardiac MRI and Chest CT; American Roentgen Ray Society; American Journal of Roentgenology; 208; 4; 4-2017; 854-8610361-803XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.ajronline.org/doi/10.2214/AJR.16.17296info:eu-repo/semantics/altIdentifier/doi/10.2214/AJR.16.17296info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:07:48Zoai:ri.conicet.gov.ar:11336/66971instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:07:48.697CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Exaggerated interventricular dependence among patients with pectus excavatum: Combined assessment with cardiac MRI and Chest CT
title Exaggerated interventricular dependence among patients with pectus excavatum: Combined assessment with cardiac MRI and Chest CT
spellingShingle Exaggerated interventricular dependence among patients with pectus excavatum: Combined assessment with cardiac MRI and Chest CT
Deviggiano, Alejandro
CHEST
CT
MRI
THORACIC MALFORMATION
THORACIC SURGERY
title_short Exaggerated interventricular dependence among patients with pectus excavatum: Combined assessment with cardiac MRI and Chest CT
title_full Exaggerated interventricular dependence among patients with pectus excavatum: Combined assessment with cardiac MRI and Chest CT
title_fullStr Exaggerated interventricular dependence among patients with pectus excavatum: Combined assessment with cardiac MRI and Chest CT
title_full_unstemmed Exaggerated interventricular dependence among patients with pectus excavatum: Combined assessment with cardiac MRI and Chest CT
title_sort Exaggerated interventricular dependence among patients with pectus excavatum: Combined assessment with cardiac MRI and Chest CT
dc.creator.none.fl_str_mv Deviggiano, Alejandro
Vallejos, Javier
Vina, Natalia
Martinez Ferro, Marcelo
Bellia Munzon, Gaston
Carrascosa, Patricia
Rodriguez Granillo, Gaston Alfredo
author Deviggiano, Alejandro
author_facet Deviggiano, Alejandro
Vallejos, Javier
Vina, Natalia
Martinez Ferro, Marcelo
Bellia Munzon, Gaston
Carrascosa, Patricia
Rodriguez Granillo, Gaston Alfredo
author_role author
author2 Vallejos, Javier
Vina, Natalia
Martinez Ferro, Marcelo
Bellia Munzon, Gaston
Carrascosa, Patricia
Rodriguez Granillo, Gaston Alfredo
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv CHEST
CT
MRI
THORACIC MALFORMATION
THORACIC SURGERY
topic CHEST
CT
MRI
THORACIC MALFORMATION
THORACIC SURGERY
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv OBJECTIVE. We sought to explore whether patients with pectus excavatum have exaggerated interventricular dependence and to evaluate the impact of the malformation severity (assessed on CT) on both anatomic and functional cardiac parameters (assessed on cardiac MRI). SUBJECTS AND METHODS. The current study involved consecutive patients with a diagnosis of pectus excavatum who were referred to undergo cardiac MRI and chest CT to establish surgical candidacy or to define treatment strategies. RESULTS. Sixty-two patients with pectus excavatum underwent cardiac MRI and chest CT. Fifty (81%) patients were male, and the median age was 17.5 years (range, 14.0-23.0 years). Forty-seven (76%) patients had evidence of right ventricular compression. The left ventricle showed a significantly decreased end-diastolic volume (inspiration vs expiration: 70.4 ± 11.6 vs 76.1 ± 13.7 mL/m2, respectively; p = 0.01) and a significantly higher eccentricity index (1.52 ± 0.2 vs 1.20 ± 0.1, p < 0.0001) during inspiration than during expiration. The median respiratory-related septal excursion was 8.1% (interquartile range, 5.1-11.7%). Patients with pericardial effusion showed a significantly higher pectus excavatum severity index than patients without pericardial effusion (6.3 ± 3.4 vs 4.4 ± 1.3, respectively; p = 0.003). Patients with a relative septal excursion equal to or larger than 11.8% showed a significantly higher pectus excavatum severity index than patients with a relative septal excursion of less than 11.8% (6.3 ± 2.6 vs 4.7 ± 2.4, respectively; p = 0.05). CONCLUSION. In this study, patients with pectus excavatum showed significant alterations of cardiac morphology and function that were related to the deformation severity and that manifest as an exaggerated interventricular dependence.
Fil: Deviggiano, Alejandro. Diagnostico Maipu; Argentina
Fil: Vallejos, Javier. Diagnostico Maipu; Argentina
Fil: Vina, Natalia. Diagnostico Maipu; Argentina
Fil: Martinez Ferro, Marcelo. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); Argentina
Fil: Bellia Munzon, Gaston. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); Argentina
Fil: Carrascosa, Patricia. Diagnostico Maipu; Argentina
Fil: Rodriguez Granillo, Gaston Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Diagnostico Maipu; Argentina
description OBJECTIVE. We sought to explore whether patients with pectus excavatum have exaggerated interventricular dependence and to evaluate the impact of the malformation severity (assessed on CT) on both anatomic and functional cardiac parameters (assessed on cardiac MRI). SUBJECTS AND METHODS. The current study involved consecutive patients with a diagnosis of pectus excavatum who were referred to undergo cardiac MRI and chest CT to establish surgical candidacy or to define treatment strategies. RESULTS. Sixty-two patients with pectus excavatum underwent cardiac MRI and chest CT. Fifty (81%) patients were male, and the median age was 17.5 years (range, 14.0-23.0 years). Forty-seven (76%) patients had evidence of right ventricular compression. The left ventricle showed a significantly decreased end-diastolic volume (inspiration vs expiration: 70.4 ± 11.6 vs 76.1 ± 13.7 mL/m2, respectively; p = 0.01) and a significantly higher eccentricity index (1.52 ± 0.2 vs 1.20 ± 0.1, p < 0.0001) during inspiration than during expiration. The median respiratory-related septal excursion was 8.1% (interquartile range, 5.1-11.7%). Patients with pericardial effusion showed a significantly higher pectus excavatum severity index than patients without pericardial effusion (6.3 ± 3.4 vs 4.4 ± 1.3, respectively; p = 0.003). Patients with a relative septal excursion equal to or larger than 11.8% showed a significantly higher pectus excavatum severity index than patients with a relative septal excursion of less than 11.8% (6.3 ± 2.6 vs 4.7 ± 2.4, respectively; p = 0.05). CONCLUSION. In this study, patients with pectus excavatum showed significant alterations of cardiac morphology and function that were related to the deformation severity and that manifest as an exaggerated interventricular dependence.
publishDate 2017
dc.date.none.fl_str_mv 2017-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/66971
Deviggiano, Alejandro; Vallejos, Javier; Vina, Natalia; Martinez Ferro, Marcelo; Bellia Munzon, Gaston; et al.; Exaggerated interventricular dependence among patients with pectus excavatum: Combined assessment with cardiac MRI and Chest CT; American Roentgen Ray Society; American Journal of Roentgenology; 208; 4; 4-2017; 854-861
0361-803X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/66971
identifier_str_mv Deviggiano, Alejandro; Vallejos, Javier; Vina, Natalia; Martinez Ferro, Marcelo; Bellia Munzon, Gaston; et al.; Exaggerated interventricular dependence among patients with pectus excavatum: Combined assessment with cardiac MRI and Chest CT; American Roentgen Ray Society; American Journal of Roentgenology; 208; 4; 4-2017; 854-861
0361-803X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.ajronline.org/doi/10.2214/AJR.16.17296
info:eu-repo/semantics/altIdentifier/doi/10.2214/AJR.16.17296
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Roentgen Ray Society
publisher.none.fl_str_mv American Roentgen Ray Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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