Role of Probiotics Against Mycotoxins and Their Deleterious Effects
- Autores
- Vinderola, Celso Gabriel; Ritieni, Alberto
- Año de publicación
- 2014
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Probiotics are live microorganisms which when administered in adequate amounts confer a health benefit on the host. They commonly belong to the genera Bifidobacterium and Lactobacillus. Fermented milks haven been used as the main vehicle, so far, for their delivery to consumers. Mycotoxins are secondary toxic fungal products with a long history of responsibility for foodborne disease outbreaks. Human and animals are continuously exposed to variable levels of these contaminants (aflatoxins, ochratoxin A, fumonisins, deoxynivalenol, patulin, zearalenone, among others) that occur naturally in the diet. The long term exposure might cause tissue and genetic damage. Certain probiotic strains can bind and remove mycotoxins from liquid media. Eukaryotic cell cultures showed that the complex probiotic-mycotoxin is less adhesive to enterocytes than the probiotic alone, then favouring maybe the elimination of this complex from the gut through feces. Probiotics were also shown capable of restoring some functions of the epithelial cells after the damage produced by mycotoxin exposure. Animal trials revealed that genetic damage and tissue oxidation might be also partially avoided by the oral administration of probiotics. Finally, human clinical trials conducted in people naturally exposed to mycotoxins in food that received probiotics, showed reduced levels of mycotoxin-DNA adducts in urine and in the content of mycotoxins in feces. However, it remains to know the fate of the ingested mycotoxins that were not found in feces. In vitro to in vivo evidence is gathering in order to determine the role of probiotics on the prevention or partial remediation of the damage induced by mycotoxins.
Fil: Vinderola, Celso Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Lactología Industrial. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Lactología Industrial; Argentina
Fil: Ritieni, Alberto. Università degli Studi di Napoli Federico II; Italia - Materia
-
Mycotoxin
Food
Probiotics
Removal - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/59334
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Role of Probiotics Against Mycotoxins and Their Deleterious EffectsVinderola, Celso GabrielRitieni, AlbertoMycotoxinFoodProbioticsRemovalhttps://purl.org/becyt/ford/2.11https://purl.org/becyt/ford/2Probiotics are live microorganisms which when administered in adequate amounts confer a health benefit on the host. They commonly belong to the genera Bifidobacterium and Lactobacillus. Fermented milks haven been used as the main vehicle, so far, for their delivery to consumers. Mycotoxins are secondary toxic fungal products with a long history of responsibility for foodborne disease outbreaks. Human and animals are continuously exposed to variable levels of these contaminants (aflatoxins, ochratoxin A, fumonisins, deoxynivalenol, patulin, zearalenone, among others) that occur naturally in the diet. The long term exposure might cause tissue and genetic damage. Certain probiotic strains can bind and remove mycotoxins from liquid media. Eukaryotic cell cultures showed that the complex probiotic-mycotoxin is less adhesive to enterocytes than the probiotic alone, then favouring maybe the elimination of this complex from the gut through feces. Probiotics were also shown capable of restoring some functions of the epithelial cells after the damage produced by mycotoxin exposure. Animal trials revealed that genetic damage and tissue oxidation might be also partially avoided by the oral administration of probiotics. Finally, human clinical trials conducted in people naturally exposed to mycotoxins in food that received probiotics, showed reduced levels of mycotoxin-DNA adducts in urine and in the content of mycotoxins in feces. However, it remains to know the fate of the ingested mycotoxins that were not found in feces. In vitro to in vivo evidence is gathering in order to determine the role of probiotics on the prevention or partial remediation of the damage induced by mycotoxins.Fil: Vinderola, Celso Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Lactología Industrial. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Lactología Industrial; ArgentinaFil: Ritieni, Alberto. Università degli Studi di Napoli Federico II; ItaliaWiley VCH Verlag2014-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/59334Vinderola, Celso Gabriel; Ritieni, Alberto; Role of Probiotics Against Mycotoxins and Their Deleterious Effects; Wiley VCH Verlag; Journal of Food Research; 4; 10-2014; 10-211927-0887CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.5539/jfr.v4n1p10info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:01:04Zoai:ri.conicet.gov.ar:11336/59334instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:01:04.732CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Role of Probiotics Against Mycotoxins and Their Deleterious Effects |
title |
Role of Probiotics Against Mycotoxins and Their Deleterious Effects |
spellingShingle |
Role of Probiotics Against Mycotoxins and Their Deleterious Effects Vinderola, Celso Gabriel Mycotoxin Food Probiotics Removal |
title_short |
Role of Probiotics Against Mycotoxins and Their Deleterious Effects |
title_full |
Role of Probiotics Against Mycotoxins and Their Deleterious Effects |
title_fullStr |
Role of Probiotics Against Mycotoxins and Their Deleterious Effects |
title_full_unstemmed |
Role of Probiotics Against Mycotoxins and Their Deleterious Effects |
title_sort |
Role of Probiotics Against Mycotoxins and Their Deleterious Effects |
dc.creator.none.fl_str_mv |
Vinderola, Celso Gabriel Ritieni, Alberto |
author |
Vinderola, Celso Gabriel |
author_facet |
Vinderola, Celso Gabriel Ritieni, Alberto |
author_role |
author |
author2 |
Ritieni, Alberto |
author2_role |
author |
dc.subject.none.fl_str_mv |
Mycotoxin Food Probiotics Removal |
topic |
Mycotoxin Food Probiotics Removal |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/2.11 https://purl.org/becyt/ford/2 |
dc.description.none.fl_txt_mv |
Probiotics are live microorganisms which when administered in adequate amounts confer a health benefit on the host. They commonly belong to the genera Bifidobacterium and Lactobacillus. Fermented milks haven been used as the main vehicle, so far, for their delivery to consumers. Mycotoxins are secondary toxic fungal products with a long history of responsibility for foodborne disease outbreaks. Human and animals are continuously exposed to variable levels of these contaminants (aflatoxins, ochratoxin A, fumonisins, deoxynivalenol, patulin, zearalenone, among others) that occur naturally in the diet. The long term exposure might cause tissue and genetic damage. Certain probiotic strains can bind and remove mycotoxins from liquid media. Eukaryotic cell cultures showed that the complex probiotic-mycotoxin is less adhesive to enterocytes than the probiotic alone, then favouring maybe the elimination of this complex from the gut through feces. Probiotics were also shown capable of restoring some functions of the epithelial cells after the damage produced by mycotoxin exposure. Animal trials revealed that genetic damage and tissue oxidation might be also partially avoided by the oral administration of probiotics. Finally, human clinical trials conducted in people naturally exposed to mycotoxins in food that received probiotics, showed reduced levels of mycotoxin-DNA adducts in urine and in the content of mycotoxins in feces. However, it remains to know the fate of the ingested mycotoxins that were not found in feces. In vitro to in vivo evidence is gathering in order to determine the role of probiotics on the prevention or partial remediation of the damage induced by mycotoxins. Fil: Vinderola, Celso Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Lactología Industrial. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Lactología Industrial; Argentina Fil: Ritieni, Alberto. Università degli Studi di Napoli Federico II; Italia |
description |
Probiotics are live microorganisms which when administered in adequate amounts confer a health benefit on the host. They commonly belong to the genera Bifidobacterium and Lactobacillus. Fermented milks haven been used as the main vehicle, so far, for their delivery to consumers. Mycotoxins are secondary toxic fungal products with a long history of responsibility for foodborne disease outbreaks. Human and animals are continuously exposed to variable levels of these contaminants (aflatoxins, ochratoxin A, fumonisins, deoxynivalenol, patulin, zearalenone, among others) that occur naturally in the diet. The long term exposure might cause tissue and genetic damage. Certain probiotic strains can bind and remove mycotoxins from liquid media. Eukaryotic cell cultures showed that the complex probiotic-mycotoxin is less adhesive to enterocytes than the probiotic alone, then favouring maybe the elimination of this complex from the gut through feces. Probiotics were also shown capable of restoring some functions of the epithelial cells after the damage produced by mycotoxin exposure. Animal trials revealed that genetic damage and tissue oxidation might be also partially avoided by the oral administration of probiotics. Finally, human clinical trials conducted in people naturally exposed to mycotoxins in food that received probiotics, showed reduced levels of mycotoxin-DNA adducts in urine and in the content of mycotoxins in feces. However, it remains to know the fate of the ingested mycotoxins that were not found in feces. In vitro to in vivo evidence is gathering in order to determine the role of probiotics on the prevention or partial remediation of the damage induced by mycotoxins. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-10 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/59334 Vinderola, Celso Gabriel; Ritieni, Alberto; Role of Probiotics Against Mycotoxins and Their Deleterious Effects; Wiley VCH Verlag; Journal of Food Research; 4; 10-2014; 10-21 1927-0887 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/59334 |
identifier_str_mv |
Vinderola, Celso Gabriel; Ritieni, Alberto; Role of Probiotics Against Mycotoxins and Their Deleterious Effects; Wiley VCH Verlag; Journal of Food Research; 4; 10-2014; 10-21 1927-0887 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.5539/jfr.v4n1p10 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Wiley VCH Verlag |
publisher.none.fl_str_mv |
Wiley VCH Verlag |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1844613800102199296 |
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13.070432 |